Schwannoma of the hypoglossal nerve: Review of the literature based on an illustrative case

  • Authors:
    • Rosario Fornaro
    • Alexander Salerno
    • David Constantin Filip
    • Elisa Caratto
    • Michela Caratto
    • Marco Casaccia
  • View Affiliations

  • Published online on: June 21, 2017     https://doi.org/10.3892/mco.2017.1297
  • Pages: 288-294
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Abstract

Schwannomas are benign tumours that originate from the myelin sheath of peripheral nerves. They are characterised by a slow growth tendency. Benign schwannomas represent 35% of the head and neck district tumours. Hypoglossal schwannomas account for 5% of non‑vestibular schwannomas, and malignant schwannomas occur very rarely. In the present case report, the case of a 49‑year‑old man who presented with paraesthesias in the left parotid and submandibular region, associated with sensation of foreign bodies and dysphagia for solids, is described. A clinical examination revealed the presence of an ovoid palpable mass in the lateral‑cervical region of the neck. The patient subsequently underwent excisional surgery, and neuropathological evaluation of the specimen confirmed the diagnosis of benign schwannoma with Antoni areas A and B. Despite the rarity of schwannomas, this condition should be considered in differential diagnoses for masses localised in the neck, as in cases where they reach considerable sizes (>3 cm in diameter). Surgery therefore represents the first‑choice treatment.

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August-2017
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Spandidos Publications style
Fornaro R, Salerno A, Filip DC, Caratto E, Caratto M and Casaccia M: Schwannoma of the hypoglossal nerve: Review of the literature based on an illustrative case. Mol Clin Oncol 7: 288-294, 2017
APA
Fornaro, R., Salerno, A., Filip, D.C., Caratto, E., Caratto, M., & Casaccia, M. (2017). Schwannoma of the hypoglossal nerve: Review of the literature based on an illustrative case. Molecular and Clinical Oncology, 7, 288-294. https://doi.org/10.3892/mco.2017.1297
MLA
Fornaro, R., Salerno, A., Filip, D. C., Caratto, E., Caratto, M., Casaccia, M."Schwannoma of the hypoglossal nerve: Review of the literature based on an illustrative case". Molecular and Clinical Oncology 7.2 (2017): 288-294.
Chicago
Fornaro, R., Salerno, A., Filip, D. C., Caratto, E., Caratto, M., Casaccia, M."Schwannoma of the hypoglossal nerve: Review of the literature based on an illustrative case". Molecular and Clinical Oncology 7, no. 2 (2017): 288-294. https://doi.org/10.3892/mco.2017.1297