Open Access

Clinical applications of mesenchymal stem cells in chronic lung diseases (Review)

  • Authors:
    • Katerina M. Antoniou
    • Konstantinos Karagiannis
    • Eliza Tsitoura
    • Eleni Bibaki
    • Ismini Lasithiotaki
    • Athanasia Proklou
    • Demetrios A. Spandidos
    • Nikos Tzanakis
  • View Affiliations

  • Published online on: February 16, 2018     https://doi.org/10.3892/br.2018.1067
  • Pages: 314-318
  • Copyright: © Antoniou et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )


Abstract

Mesenchymal stem (stromal) cells (MSCs) are multipotent stromal cells that have the ability to modulate immune response to tissue injury and promote repair in vivo. The therapeutic potential of ex vivo expanded MSCs are currently under investigation for a variety of chronic and acute lung diseases. This review summarizes the encouraging results regarding the safety of MSCs administration from recent and current clinical trials for idiopathic pulmonary fibrosis, acute respiratory distress syndrome, and chronic obstructive pulmonary disease. It also reviews the early preliminary data extracted by the same trials regarding the efficacy of MSCs in the aforementioned lung diseases.
View References

Related Articles

Journal Cover

April-2018
Volume 8 Issue 4

Print ISSN: 2049-9434
Online ISSN:2049-9442

Sign up for eToc alerts

Recommend to Library

Copy and paste a formatted citation
x
Spandidos Publications style
Antoniou KM, Karagiannis K, Tsitoura E, Bibaki E, Lasithiotaki I, Proklou A, Spandidos DA and Tzanakis N: Clinical applications of mesenchymal stem cells in chronic lung diseases (Review). Biomed Rep 8: 314-318, 2018
APA
Antoniou, K.M., Karagiannis, K., Tsitoura, E., Bibaki, E., Lasithiotaki, I., Proklou, A. ... Tzanakis, N. (2018). Clinical applications of mesenchymal stem cells in chronic lung diseases (Review). Biomedical Reports, 8, 314-318. https://doi.org/10.3892/br.2018.1067
MLA
Antoniou, K. M., Karagiannis, K., Tsitoura, E., Bibaki, E., Lasithiotaki, I., Proklou, A., Spandidos, D. A., Tzanakis, N."Clinical applications of mesenchymal stem cells in chronic lung diseases (Review)". Biomedical Reports 8.4 (2018): 314-318.
Chicago
Antoniou, K. M., Karagiannis, K., Tsitoura, E., Bibaki, E., Lasithiotaki, I., Proklou, A., Spandidos, D. A., Tzanakis, N."Clinical applications of mesenchymal stem cells in chronic lung diseases (Review)". Biomedical Reports 8, no. 4 (2018): 314-318. https://doi.org/10.3892/br.2018.1067