Augmentation of the anticancer activity of CYT997 in human prostate cancer by inhibiting Src activity
Yong Teng et al, 2017, Journal of Hematology & Oncology CrossRef
Angiogenesis and anti-leukaemia activity of novel indole derivatives as potent colchicine binding site inhibitors
Yongfang Yao et al, 2022, Journal of Enzyme Inhibition and Medicinal Chemistry CrossRef
Early investigational tubulin inhibitors as novel cancer therapeutics
Kunal Nepali et al, 2016, Expert Opinion on Investigational Drugs CrossRef
Identification and validation of microtubule depolymerizing agent, CYT997, as a potential drug candidate for hepatocellular carcinoma
Faiz Ahmad et al, 2023, Liver International CrossRef
Structures of a diverse set of colchicine binding site inhibitors in complex with tubulin provide a rationale for drug discovery
Yuxi Wang et al, 2016, The FEBS Journal CrossRef
Patient-tailored design for selective co-inhibition of leukemic cell subpopulations
Aleksandr Ianevski et al, 2021, Science Advances CrossRef
Plumbagin inhibits cell proliferation and promotes apoptosis in multiple myeloma cells through inhibition of the PI3K/Akt-mTOR pathway
Hongwei Wu et al, 2016, Oncology Letters CrossRef
PP2A inhibition from LB100 therapy enhances daunorubicin cytotoxicity in secondary acute myeloid leukemia via miR-181b-1 upregulation
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Mitochondrial ROS accumulation inhibiting JAK2/STAT3 pathway is a critical modulator of CYT997-induced autophagy and apoptosis in gastric cancer
Ya Cao et al, 2020, Journal of Experimental & Clinical Cancer Research CrossRef
Autophagy blockade sensitizes human head and neck squamous cell carcinoma towards CYT997 through enhancing excessively high reactive oxygen species-induced apoptosis
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Transcriptomic analysis reveals proinflammatory signatures associated with acute myeloid leukemia progression
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