1. Jiangtang decoction ameliorate diabetic nephropathy through the regulation of PI3K/Akt-mediated NF-κB pathways in KK-Ay mice.
   Jin-Ni Hong et al, 2017, Chin Med CrossRef
2. Therapeutic Potential and Mechanisms of Berberine in Cardiovascular Disease
   Ming Zhang et al, 2016, Curr Pharmacol Rep CrossRef
3. Study on the Absorption Mechanism of Geniposide in the Chinese Formula Huang-Lian-Jie-Du-Tang in Rats
   Dan Yu et al, 2017, AAPS PharmSciTech CrossRef
4. Rhizoma Coptidis: A Potential Cardiovascular Protective Agent
   Hui-Li Tan et al, 2016, Front. Pharmacol. CrossRef
5. Immune and Metabolic Regulation Mechanism of Dangguiliuhuang Decoction against Insulin Resistance and Hepatic Steatosis
   Hui Cao et al, 2017, Front. Pharmacol. CrossRef
6. Simultaneous determination of anemoside B4, phellodendrine, berberine, palmatine, obakunone, esculin, esculetin in rat plasma by UPLC–ESI–MS/MS and its application to a comparative pharmacokinetic study in normal and ulcerative colitis rats
   Lianrong Yang et al, 2017, Journal of Pharmaceutical and Biomedical Analysis CrossRef
7. Protective effect of berberine against cardiac ischemia/reperfusion injury by inhibiting apoptosis through the activation of Smad7
   Weidong Yao et al, 2017, Molecular and Cellular Probes CrossRef
8. Berberine alleviates symptoms of anxiety by enhancing dopamine expression in rats with post-traumatic stress disorder
   Bombi Lee et al, 2018, Korean J Physiol Pharmacol CrossRef
9. Coptidis rhizoma and its main bioactive components: recent advances in chemical investigation, quality evaluation and pharmacological activity
   Fan-Cheng Meng et al, 2018, Chin Med CrossRef
10. Antioxidant and anti-inflammatory activities of berberine attenuate hepatic fibrosis induced by thioacetamide injection in rats
    Laila Ahmed Eissa et al, 2018, Chemico-Biological Interactions CrossRef
11. Long noncoding RNA RMRP upregulation aggravates myocardial ischemia-reperfusion injury by sponging miR-206 to target ATG3 expression
    Fei Kong et al, 2019, Biomedicine & Pharmacotherapy CrossRef
12. LDK378 improves micro- and macro-circulation via alleviating STING-mediated inflammatory injury in a Sepsis rat model induced by Cecal ligation and puncture
    Weiwei Ge et al, 2019, J Inflamm CrossRef
13. Targeting autophagy in cardiac ischemia/reperfusion injury: A novel therapeutic strategy
    Mehrdad Aghaei et al, 2019, J Cell Physiol CrossRef
14. Attenuation of Myocardial ischemia reperfusion injury by Geniposide preconditioning in diabetic rats
    Jia wang et al, 2019, Current Research in Translational Medicine CrossRef
15. Coptidis Rhizoma: a comprehensive review of its traditional uses, botany, phytochemistry, pharmacology and toxicology.
    Jin Wang et al, 2019, Pharm Biol CrossRef
16. Up-regulation of microRNA-203 inhibits myocardial fibrosis and oxidative stress in mice with diabetic cardiomyopathy through the inhibition of PI3K/Akt signaling pathway via PIK3CA.
    Xubin Yang et al, 2019, Gene CrossRef
17. Allicin Attenuates Myocardial Ischemia Reperfusion Injury in Rats by Inhibition of Inflammation and Oxidative Stress
    Shengzhong Liu et al, 2019, Transplantation Proceedings CrossRef
18. Tetrahydroberberrubine attenuates lipopolysaccharide-induced acute lung injury by down-regulating MAPK, AKT, and NF-κB signaling pathways.
    Xiu Yu et al, 2016, Biomed Pharmacother CrossRef
19. Chronic over-nutrition and dysregulation of GSK3 in diseases
    Xunxian Liu et al, 2016, Nutr Metab (Lond) CrossRef
20. Effects and mechanisms of compound Chinese medicine and major ingredients on microcirculatory dysfunction and organ injury induced by ischemia/reperfusion
    Jing-Yan Han et al, 2017, Pharmacology & Therapeutics CrossRef
21. Berberine alleviates monosodium glutamate induced postnatal metabolic disorders associated vascular endothelial dysfunction in newborn rats: possible role of matrix metalloproteinase-1
    Abeer A. Abo Zeid et al, 2020, Archives of Physiology and Biochemistry CrossRef
22. Metabolic characterization and pathway analysis of berberine protects against prostate cancer
    Xianna Li et al, 2017, Oncotarget CrossRef
23. NLRP3 Inflammasome Activation in Lung Vascular Endothelial Cells Contributes to Intestinal Ischemia/Reperfusion-Induced Acute Lung Injury
    Homare Ito et al, 2020, J.I. CrossRef
24. Protective effects of berberine in a rat model of polycystic ovary syndrome mediated via the PI3K / AKT pathway
    Jia Yu et al, 2021, J. Obstet. Gynaecol. Res. CrossRef
25. Therapeutic modulation of the phosphatidylinositol 3-kinases (PI3K) pathway in cerebral ischemic injury
    Heena Khan et al, 2021, Brain Research CrossRef
26. Pre-clinical Evidence: Berberine as a Promising Cardioprotective Candidate for Myocardial Ischemia/Reperfusion Injury, a Systematic Review, and Meta-Analysis
    Cong Chen et al, 2021, Front. Cardiovasc. Med. CrossRef
27. LianXia Formula Granule Attenuates Cardiac Sympathetic Remodeling in Rats with Myocardial Infarction via the NGF/TrKA/PI3K/AKT Signaling Pathway
    Sai-Sai Li et al, 2021, Evidence-Based Complementary and Alternative Medicine CrossRef
28. Akt Inhibition as Preconditioning Treatment to Protect Kidney Cells against Anoxia
    Nicolas Melis et al, 2021, IJMS CrossRef
29. Efficacy and safety of Chinese herbal for carotid atherosclerosis
    Haitao Li et al, 2021 CrossRef
30. Promising Antioxidative Effect of Berberine in Cardiovascular Diseases
    Na An et al, 2022, Front. Pharmacol. CrossRef
31. Berberine up‐regulates miR‐340‐5p to protect myocardial ischaemia/reperfusion from HMGB1‐mediated inflammatory injury
    Tianyi Long et al, 2022, ESC Heart Failure CrossRef
32. Efficacy and safety of berberine for several cardiovascular diseases: a systematic review and meta-analysis of randomized controlled trials
    Lele Yang et al, 2023, Phytomedicine CrossRef
33. Natural Products Targeting PI3K/AKT in Myocardial Ischemic Reperfusion Injury: A Scoping Review
    Syarifah Aisyah Syed Abd Halim et al, 2023, Pharmaceuticals CrossRef
34. The pharmacological effects of Berberine and its therapeutic potential in different diseases: Role of the phosphatidylinositol 3‐kinase/AKT signaling pathway
    Mohammad Rafi Khezri et al, 2023, Phytotherapy Research CrossRef
35. Exploring the therapeutic mechanisms of Coptidis Rhizoma in gastric precancerous lesions: a network pharmacology approach
    Xuxing Ye et al, 2024, Discov Onc CrossRef
36. Research progress on pharmacological effects and bioavailability of berberine
    Yulong Cui et al, 2024, Naunyn-Schmiedeberg's Arch Pharmacol CrossRef
37. Berberine Alleviates Uterine Inflammation in Rats via Modulating the TLR-2/p-PI3K/p-AKT Axis
    Rawan H. Hareeri et al, 2024, International Immunopharmacology CrossRef