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2. Shikonin ameliorates isoproterenol (ISO)-induced myocardial damage through suppressing fibrosis, inflammation, apoptosis and ER stress.
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3. Decorin reduces hypertrophic scarring through inhibition of the TGF-β1/Smad signaling pathway in a rat osteomyelitis model
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4. Growth factor pathways in hypertrophic scars: Molecular pathogenesis and therapeutic implications
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5. Shikonin suppresses pulmonary fibroblasts proliferation and activation by regulating Akt and p38 MAPK signaling pathways
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6. Inactivation of Beclin-1-dependent autophagy promotes ursolic acid-induced apoptosis in hypertrophic scar fibroblasts
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7. Cutaneous wound healing using polymeric surgical dressings based on chitosan, sodium hyaluronate and resveratrol. A preclinical experimental study
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8. Development of a Porcine Full-Thickness Burn Hypertrophic Scar Model and Investigation of the Effects of Shikonin on Hypertrophic Scar Remediation
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9. Alleviation of hepatic fibrosis and autophagy via inhibition of transforming growth factor-β 1/Smads pathway through shikonin
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10. Current and upcoming therapies to modulate skin scarring and fibrosis.
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11. Application of “macromolecular crowding” in vitro to investigate the naphthoquinones shikonin, naphthazarin and related analogues for the treatment of dermal scars
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12. Baicalein inhibits proliferation and collagen synthesis of mice fibroblast cell line NIH/3T3 by regulation of miR-9/insulin-like growth factor-1 axis
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13. The evidence for natural therapeutics as potential anti-scarring agents in burn-related scarring
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15. Role of Early Application of Pressure Garments following Burn Injury and Autografting
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16. Wnt4 negatively regulates the TGF-β1-induced human dermal fibroblast-to-myofibroblast transition via targeting Smad3 and ERK
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17. Research on function and mechanisms of a novel small molecule WG 449E for hypertrophic scar
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19. Evidence-based therapy in hypertrophic scars: An update of a systematic review.
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20. MicroRNA-26a inhibits hyperplastic scar formation by targeting Smad2
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21. Downregulation of Epac Reduces Fibrosis and Induces Apoptosis Through Akt Signaling in Human Keloid Fibroblasts
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22. Plants of the Genus Terminalia: An Insight on Its Biological Potentials, Pre-Clinical and Clinical Studies
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23. Tanshinone IIA down-regulated p-Smad3 signaling to inhibit TGF-β1-mediated fibroblast proliferation via lncRNA-HSRL/SNX9
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24. The Biology of Extracellular Matrix Proteins in Hypertrophic Scarring
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25. Transdermal delivery of Chinese herbal medicine extracts using dissolvable microneedles for hypertrophic scar treatment
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26. USP15 Enhances the Proliferation, Migration, and Collagen Deposition of Hypertrophic Scar–Derived Fibroblasts by Deubiquitinating TGF-βR1 In Vitro
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27. Shikonin, a naphthalene ingredient: Therapeutic actions, pharmacokinetics, toxicology, clinical trials and pharmaceutical researches
    Qiang Sun et al, 2021, Phytomedicine CrossRef
28. In vitro antioxidant, anticholinesterase inhibitory, and antimicrobial activity studies of Terminalia chebula (Retz) and Terminalia arjuna (Roxb)
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29. Therapeutic Effects of Shikonin on Skin Diseases: A Review
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30. Plants and phytochemicals inhibit scar formation: A systematic review
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31. Assessment of Skin Photoallergy Risk in Cosmetics Containing Herbal Extract Ingredients
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32. Exploring the mechanism of MP gel against skin photoaging based on network pharmacology, molecular docking, and experimental validation
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33. High-performance thin-layer chromatography fingerprint profile analysis and spectro-densitometric evaluation of antiproliferative antioxidants such as ellagic acid and gallic acid from four widely used Terminalia species
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34. A Study on Phytochemical and Pharmacological activity of Terminalia arjuna: A Review
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35. Gallic Acid Treats Hypertrophic Scar in Rabbit Ears via the TGF-β/Smad and TRPC3 Signaling Pathways
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37. Potential Efficacy of Shiunko for Anti-Epidermal Growth Factor Receptor (EGFR) Monoclonal Antibody-Induced Skin Fissure: A Single Institutional Case Series
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38. Pharmacotherapy for Keloids and Hypertrophic Scars
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