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  3. Serum Cyr61 as a potential biomarker for diagnosis of colorectal cancer
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  4. Human pancreatic cancer progression: an anarchy among CCN-siblings
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  5. Hypoxia and Redox Signaling on Extracellular Matrix Remodeling: From Mechanisms to Pathological Implications
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  6. TGF-β1 Inhibits Human Trophoblast Cell Invasion by Upregulating Connective Tissue Growth Factor Expression.
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  7. Advanced glycation end products promote VEGF expression and thus choroidal neovascularization via Cyr61-PI3K/AKT signaling pathway
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  10. Molecular Determinants of Malignant Brain Cancers: From Intracellular Alterations to Invasion Mediated by Extracellular Vesicles
    Gabriella Schiera et al, 2017, IJMS CrossRef
  11. WISP1 genetic variants as predictors of tumor development with urothelial cell carcinoma
    Hsiang-Lin Lee et al, 2017, Urologic Oncology: Seminars and Original Investigations CrossRef
  12. Clinical relevance of Cyr61 expression in patients with hormone-dependent breast cancer
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  13. Association Between Genetic Polymorphisms of WNT1 Inducible Signaling Pathway Protein 1 and Uterine Cervical Cancer
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  16. Rare germline variants in DNA repair genes and the angiogenesis pathway predispose prostate cancer patients to develop metastatic disease
    Martina Mijuskovic et al, 2018, Br J Cancer CrossRef
  17. Role of CCN5 (WNT1 inducible signaling pathway protein 2) in pancreatic islets
    Jun-Li Liu et al, 2017, J Diabetes CrossRef
  18. LncRNA-p23154 promotes the invasion-metastasis potential of oral squamous cell carcinoma by regulating Glut1-mediated glycolysis
    Yun Wang et al, 2018, Cancer Letters CrossRef
  19. Polymorphisms of the CYR61 gene in patients with acute myeloid leukemia in a Han Chinese population
    Chang-Chun Niu et al, 2018, Medicine CrossRef
  20. CCN6-mediated MMP-9 activation enhances metastatic potential of human chondrosarcoma.
    Huey-En Tzeng et al, 2018, Cell Death Dis CrossRef
  21. Maternal western-style diet enhances the effects of chemically-induced mammary tumors in female rat offspring through transcriptome changes
    Tony F. Grassi et al, 2018, Nutrition Research CrossRef
  22. Novel treatment avenues for uterine leiomyoma: a new implication for endothelin?
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  23. CCN3 and DLL1 co-regulate osteogenic differentiation of mouse embryonic fibroblasts in a Hey1-dependent manner
    Xin Su et al, 2018, Cell Death Dis CrossRef
  24. WISP2 exhibits its potential antitumor activity via targeting ERK and E-cadherin pathways in esophageal cancer cells
    Da-Min Chai et al, 2019, J Exp Clin Cancer Res CrossRef
  25. WISP1 is associated to advanced disease, EMT and an inflamed tumor microenvironment in multiple solid tumors
    Pierre-Olivier Gaudreau et al, 2019, OncoImmunology CrossRef
  26. WISP1 Is a Marker of Systemic and Adipose Tissue Inflammation in Dysmetabolic Subjects With or Without Type 2 Diabetes
    Ilaria Barchetta et al, 2017 CrossRef
  27. Role of the CCN protein family in cancer
    Hyungjoo Kim et al, 2018, BMB Rep. CrossRef
  28. CCN3/Nephroblastoma Overexpressed Is a Functional Mediator of Prostate Cancer Bone Metastasis That Is Associated with Poor Patient Prognosis
    Matthew Dankner et al, 2019, The American Journal of Pathology CrossRef
  29. CCN2–MAPK–Id-1 loop feedback amplification is involved in maintaining stemness in oxaliplatin-resistant hepatocellular carcinoma
    Xia Liao et al, 2019, Hepatol Int CrossRef
  30. Expression analysis of genes located within the common deleted region of del(20q) in patients with myelodysplastic syndromes
    Masayuki Shiseki et al, 2019, Leukemia Research CrossRef
  31. Overexpression of connective tissue growth factor is associated with tumor progression and unfavorable prognosis in endometrial cancer
    Xue-Ting Li et al, 2019, CBM CrossRef
  32. Adhesion molecules and the extracellular matrix as drug targets for glioma
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  34. The CCN family of proteins: a 25th anniversary picture
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  35. Role of Matricellular Proteins in Disorders of the Central Nervous System
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  36. Effect of genetic variation in microRNA binding site in WNT1-inducible signaling pathway protein 1 gene on oral squamous cell carcinoma susceptibility
    Hon-Kit Lau et al, 2017, PLoS ONE CrossRef
  37. Difference in morphology and interactome profiles between orthotopic and subcutaneous gastric cancer xenograft models
    Kiyotaka Nakano et al, 2018, J Toxicol Pathol CrossRef
  38. RASSF1A–Hippo pathway link in patients with urothelial carcinoma of bladder: plausible therapeutic target
    Madhuram Khandelwal et al, 2019, Mol Cell Biochem CrossRef
  39. Remodeling of hepatic stellate cells orchestrated the stroma-derived oxaliplatin-resistance through CCN3 paracrine in hepatocellular carcinoma
    Xia Liao et al, 2019, BMC Cancer CrossRef
  40. ROCK2 deprivation leads to the inhibition of tumor growth and metastatic potential in osteosarcoma cells through the modulation of YAP activity
    Cinzia Zucchini et al, 2019, J Exp Clin Cancer Res CrossRef
  41. The thrombospondin module 1 domain of the matricellular protein CCN3 shows an atypical disulfide pattern and incomplete CWR layers
    Emma-Ruoqi Xu et al, 2020, Acta Crystallogr D Struct Biol CrossRef
  42. Nov/CCN3 Enhances Cord Blood Engraftment by Rapidly Recruiting Latent Human Stem Cell Activity
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  43. Reduced NOV expression correlates with disease progression in colorectal cancer and is associated with survival, invasion and chemoresistance of cancer cells
    Jun Li et al, 2017, Oncotarget CrossRef
  44. WISP-3 inhibition of miR-452 promotes VEGF-A expression in chondrosarcoma cells and induces endothelial progenitor cells angiogenesis
    Chih-Yang Lin et al, 2017, Oncotarget CrossRef
  45. Sphingosine-1-phosphate promotes ovarian cancer cell proliferation by disrupting Hippo signaling.
    Qianlan Fan et al, 0 CrossRef
  46. Matricellular protein CCN1 mediates doxorubicin-induced cardiomyopathy in mice
    Pei-Ling Hsu et al, 2016, Oncotarget CrossRef
  47. CCN3 promotes epithelial-mesenchymal transition in prostate cancer via FAK/Akt/HIF-1α-induced twist expression
    Po-Chun Chen et al, 2017, Oncotarget CrossRef
  48. Eyeing the Extracellular Matrix in Vascular Development and Microvascular Diseases and Bridging the Divide between Vascular Mechanics and Function
    Brahim Chaqour et al, 2020, IJMS CrossRef
  49. WISP1 Predicts Clinical Prognosis and Is Associated With Tumor Purity, Immunocyte Infiltration, and Macrophage M2 Polarization in Pan-Cancer
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  50. Dual Role of WISP1 in maintaining glioma stem cells and tumor-supportive macrophages in glioblastoma
    Weiwei Tao et al, 2020, Nat Commun CrossRef
  51. WISP2 promotes cell proliferation via targeting ERK and YAP in ovarian cancer cells
    Zi-Qing Shi et al, 2020, J Ovarian Res CrossRef
  52. Verteporfin inhibits cell proliferation and induces apoptosis in different subtypes of breast cancer cell lines without light activation
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  54. The Matrix Revolution: Matricellular Proteins and Restructuring of the Cancer Microenvironment.
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  55. Endothelial YAP/TAZ Signaling in Angiogenesis and Tumor Vasculature
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  56. CCN Family Proteins in Cancer: Insight Into Their Structures and Coordination Role in Tumor Microenvironment
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  57. Nephroblastoma overexpressed protein (NOV) enhances 5-Fu-mediated inhibitory effect of colorectal cancer cell proliferation via JNK/AP-1/caspase-8/caspase-3 pathway.
    Dong Wang et al, 2021, Discov Oncol CrossRef
  58. Role of Matricellular CCN Proteins in Skeletal Muscle: Focus on CCN2/CTGF and Its Regulation by Vasoactive Peptides
    Daniela L. Rebolledo et al, 2021, IJMS CrossRef
  59. The Emerging Roles of CCN3 Protein in Immune-Related Diseases
    Linan Peng et al, 2021, Mediators of Inflammation CrossRef
  60. Cellular communication network factor 3 in cartilage development and maintenance
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  61. Functions of Matricellular Proteins in Dental Tissues and Their Emerging Roles in Orofacial Tissue Development, Maintenance, and Disease
    Georgia Nikoloudaki, 2021, IJMS CrossRef
  62. Plasminogen Regulates Fracture Repair by Promoting the Functions of Periosteal Mesenchymal Progenitors
    Luqiang Wang et al, 2021, J Bone Miner Res CrossRef
  63. Rapid testing of candidate oncogenes and tumour suppressor genes in signal transduction and neoplastic transformation
    Sha Liu et al, 2021, Advances in Biological Regulation CrossRef
  64. The multifaceted role of Matricellular Proteins in health and cancer, as biomarkers and therapeutic targets
    Prarthana Gopinath et al, 2022, Gene CrossRef
  65. Multifunctional regulatory protein connective tissue growth factor (CTGF): A potential therapeutic target for diverse diseases
    Minyang Fu et al, 2022, Acta Pharmaceutica Sinica B CrossRef
  66. Lamin A and the LINC complex act as potential tumor suppressors in Ewing Sarcoma
    Francesca Chiarini et al, 2022, Cell Death Dis CrossRef
  67. Hypoxia reveals a new function of Foxn1 in the keratinocyte antioxidant defense system
    Sylwia Machcinska et al, 2022, The FASEB Journal CrossRef
  68. Regulation of CyR61 expression and release by 3-mercaptopyruvate sulfurtransferase in colon cancer cells
    Kelly Ascenção et al, 2022, Redox Biology CrossRef
  69. CCN6 improves hepatic steatosis, inflammation, and fibrosis in non‐alcoholic steatohepatitis
    Yiran Song et al, 2022, Liver International CrossRef
  70. Reprogramming of cancer-associated fibroblasts by apoptotic cancer cells inhibits lung metastasis via Notch1-WISP-1 signaling
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  73. Decidualization of human endometrial stromal cells requires steroid receptor coactivator-3
    Vineet K. Maurya et al, 2022, Front. Reprod. Health CrossRef
  74. CCN1 promotes hepatic steatosis and inflammation in non-alcoholic steatohepatitis
    Linling Ju et al, 2020, Sci Rep CrossRef
  75. Insulin-like growth factor-binding protein-7 (IGFBP7) links senescence to heart failure
    Liyong Zhang et al, 2022, Nat Cardiovasc Res CrossRef
  76. TYRO3 blockade enhances anti-PD-1 therapy response by modulating expression of CCN1 in tumor microenvironment
    Miso Park et al, 2023, J Immunother Cancer CrossRef
  77. From outside to inside and back again: the lysophosphatidic acid-CCN axis in signal transduction
    Pravita Balijepalli et al, 2023, J. Cell Commun. Signal. CrossRef
  78. Knockdown SENP1 Suppressed the Angiogenic Potential of Mesenchymal Stem Cells by Impacting CXCR4-Regulated MRTF-A SUMOylation and CCN1 Expression
    Rui Zhang et al, 2023, Biomedicines CrossRef
  79. CCN proteins: opportunities for clinical studies—a personal perspective
    Herman Yeger, 2023, J. Cell Commun. Signal. CrossRef
  80. WISP2 downregulation inhibits the osteogenic differentiation of BMSCs in congenital scoliosis by regulating Wnt/β-catenin pathway
    Yang Zheng et al, 2023, Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease CrossRef
  81. Ligand-independent signaling and migration of breast cancer cells expressing membrane androgen receptor, ZIP9 (SLC39A9)
    Peter Thomas et al, 2023, Molecular and Cellular Endocrinology CrossRef
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  83. YAP silencing by RB1 mutation is essential for small-cell lung cancer metastasis
    Zhengming Wu et al, 2023, Nat Commun CrossRef
  84. Therapeutic strategies to target connective tissue growth factor in fibrotic lung diseases
    Takuma Isshiki et al, 2023, Pharmacology & Therapeutics CrossRef
  85. Cancer stem cells: Signaling pathways and therapeutic targeting
    Joyeeta Talukdar et al, 2023, MedComm – Oncology CrossRef
  86. Role for CCN1 in lysophosphatidic acid response in PC‐3 human prostate cancer cells
    Pravita Balijepalli et al, 2024, Journal of Cell Communication and Signaling CrossRef