1. Anti-Inflammatory Pyranochalcone Derivative Attenuates LPS-Induced Acute Kidney Injury via Inhibiting TLR4/NF-κB Pathway
    Min Shi et al, 2017, Molecules CrossRef
  2. Lipopolysaccharide-induced neutrophil extracellular trap formation in canine neutrophils is dependent on histone H3 citrullination by peptidylarginine deiminase
    Ronald H.L. Li et al, 2017, Veterinary Immunology and Immunopathology CrossRef
  3. Neutrophil Phenotype Correlates With Postoperative Inflammatory Outcomes in Infants Undergoing Cardiopulmonary Bypass
    Jody N. Huber et al, 2017, Pediatric Critical Care Medicine CrossRef
  4. Polymorphonuclear (PMN) elastase in patients after severe traumatic brain injury
    Lukas Kurt Postl et al, 2018, Eur J Med Res CrossRef
  5. Neutrophil-released enzymes can influence composition of circulating immune complexes in multiple sclerosis
    S. Paryzhak et al, 2018, Autoimmunity CrossRef
  6. Role of using two-route ulinastatin injection to alleviate intestinal injury in septic rats
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  7. Neutrophil Elastase Damages the Pulmonary Endothelial Glycocalyx in Lipopolysaccharide-Induced Experimental Endotoxemia
    Kodai Suzuki et al, 2019, The American Journal of Pathology CrossRef
  8. Mechanisms of haemolysis-induced kidney injury
    Kristof Van Avondt et al, 2019, Nat Rev Nephrol CrossRef
  9. HMGB1 in kidney diseases
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  10. Neutrophil Elastase Inhibition Ameliorates Endotoxin-induced Myocardial Injury Accompanying Degradation of Cardiac Capillary Glycocalyx
    Tetsuya Fukuta et al, 2020 CrossRef
  11. Physics-driven identification of FDA-approved drugs against human neutrophil serine protease 4 (NSP4): A Virtual Drug Repurposing Study
    Jamshaid Ahmad et al, 2020, Journal of Molecular Graphics and Modelling CrossRef
  12. Sivelestat-loaded nanostructured lipid carriers modulate oxidative and inflammatory stress in human dental pulp and mesenchymal stem cells subjected to oxygen-glucose deprivation
    Ravi Prakash et al, 2020, Materials Science and Engineering: C CrossRef
  13. Neutrophil elastase inhibitor (MPH-966) improves intestinal mucosal damage and gut microbiota in a mouse model of 5-fluorouracil–induced intestinal mucositis
    Kung-Ju Chen et al, 2021, Biomedicine & Pharmacotherapy CrossRef
  14. Tofacitinib Ameliorates Lipopolysaccharide-Induced Acute Kidney Injury by Blocking the JAK-STAT1/STAT3 Signaling Pathway
    Yang Yun et al, 2021, BioMed Research International CrossRef
  15. Characterization and functional analysis of cathelicidin-MH, a novel frog-derived peptide with anti-septicemic properties.
    Jinwei Chai et al, 2021, Elife CrossRef
  16. The Therapeutic Value of Hydralazine in Reducing Inflammatory Response, Oxidative Stress, and Mortality in Animal Sepsis: Involvement of the PI3K/AKT Pathway
    Danillo Menezes dos Santos et al, 2021 CrossRef
  17. Tissue neutrophil elastase contributes to extracorporeal shock wave lithotripsy-induced kidney damage and the neutrophil elastase inhibitor, sivelestat, attenuates kidney damage with gratifying immunohistopathological and biochemical findings: an experimental study
    Aykut Colakerol et al, 2021, Urolithiasis CrossRef
  18. Positive Effects of Neutrophil Elastase Inhibitor (Sivelestat) on Gut Microbiome and Metabolite Profiles of Septic Rats
    Yali Sun et al, 2022, Front. Cell. Infect. Microbiol. CrossRef
  19. Granulocyte microvesicles with a high plasmin generation capacity promote clot lysis and improve outcome in septic shock
    Sylvie Cointe et al, 2022 CrossRef
  20. Egg white protein hydrolysate ameliorated sepsis-induced inflammatory injuries in kidney and liver based on metabolomics analysis
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  21. Clinical Utility of the Sivelestat for the Treatment of ALI/ARDS: Moving on in the Controversy?
    Qiongli Ding et al, 2022, Intensive Care Res CrossRef
  22. A new approach to combat the sepsis including COVID-19 by accelerating detoxification of hemolysis-related DAMPs
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  23. The Potential Importance of CXCL1 in the Physiological State and in Noncancer Diseases of the Cardiovascular System, Respiratory System and Skin
    Jan Korbecki et al, 2022, IJMS CrossRef
  24. Polysulfone Membranes Doped with Human Neutrophil Elastase Inhibitors: Assessment of Bioactivity and Biocompatibility
    Susana Rocha et al, 2023, Membranes CrossRef
  25. Predictive Value of Lactate Dehydrogenase Combined with the Abbreviated Burn Severity Index for Acute Kidney Injury and Mortality in Severe Burn Patients
    Ming Jiang et al, 2023, Burns CrossRef
  26. Tofacitinib reduces acute lung injury and improves survival in a rat model of sepsis by inhibiting the JAK-STAT/NF-κB pathway
    Xinxin Zhang et al, 2023, J Inflamm CrossRef
  27. Trypsin is inhibited by phytocompounds liquiritin and terpinen-4-ol from the herb Glycyrrhiza glabra: in vitro and in silico studies
    J. Abhithaj et al, 2023, Journal of Biomolecular Structure and Dynamics CrossRef
  28. Resolving neutrophils due to TRAM deletion renders protection against experimental sepsis
    RuiCi Lin et al, 2023, Inflamm. Res. CrossRef
  29. Decreased neutrophil counts prolong inflammation in acute pancreatitis and cause inflammation spillover to distant organs
    Yohei Fukuda et al, 2023, Pancreatology CrossRef
  30. Sivelestat ameliorates sepsis-induced myocardial dysfunction by activating the PI3K/AKT/mTOR signaling pathway
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  31. Human neutrophil elastase inhibitors: Classification, biological‐synthetic sources and their relevance in related diseases
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  32. A neutrophil elastase inhibitor, sivelestat, attenuates sepsis-induced acute kidney injury by inhibiting oxidative stress
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  33. Taking advantage of the interaction between the sulfoxide and heme cofactor to develop indoleamine 2, 3-dioxygenase 1 inhibitors
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