1. Risk factors for MEK-associated retinopathy in patients with advanced melanoma treated with combination BRAF and MEK inhibitor therapy
    Andrew E. C. Booth et al, 2020, Therapeutic Advances in Medical Oncology CrossRef
  2. Detrimental Effects of UVB on Retinal Pigment Epithelial Cells and Its Role in Age-Related Macular Degeneration
    Camille Keisha Mahendra et al, 2020, Oxidative Medicine and Cellular Longevity CrossRef
  3. Exudative retinal detachment
    Radgonde Amer et al, 2017, Survey of Ophthalmology CrossRef
  4. New features in MEK retinopathy
    Pallavi Tyagi et al, 2018, BMC Ophthalmology CrossRef
  5. Favorable Management of Repeated Serous Retinal Detachment with Continued Tumor Response in a Patient with Intrahepatic Cholangiocarcinoma during Treatment with Pemigatinib
    Masanobu Yukutake et al, 2023, Internal Medicine CrossRef
  6. Drug-Induced Pseudo-Central Serous Chorioretinopathy in Carcinoma Patients
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  7. Wide field retinal imaging and the detection of drug associated retinal toxicity
    Giulia Corradetti et al, 2019, International Journal of Retina and Vitreous CrossRef
  8. Retinal toxicities of systemic anticancer drugs
    Supriya Arora et al, 2022, Survey of Ophthalmology CrossRef
  9. Cystoid Macular Edema
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  10. Neoplasia and intraocular inflammation: From masquerade syndromes to immunotherapy-induced uveitis
    Sara Touhami et al, 2019, Progress in Retinal and Eye Research CrossRef
  11. Bilateral Serous Retinal Detachment Associated with a Mitogen-activated Protein KinaseKinase Inhibitor in a Patient with BRAF-mutant Colorectal Cancer
    Miho Sakumura et al, 2022, Internal Medicine CrossRef
  12. 5-Hydroxymethyl-Furfural and Structurally Related Compounds Block the Ion Conductance in Human Aquaporin-1 Channels and Slow Cancer Cell Migration and Invasion
    Pak Hin Chow et al, 2020, Molecular Pharmacology CrossRef
  13. Ocular Inflammatory Complications of Treatment for Metastatic Melanoma
    Andrew M. Philip et al, 2023, Ocular Immunology and Inflammation CrossRef
  14. Bilateral Multifocal Central Serous-Like Chorioretinopathy due to MEK Inhibition for Metastatic Cutaneous Melanoma
    Scott D. Schoenberger et al, 2013, Case Reports in Ophthalmological Medicine CrossRef
  15. Assessment of Retinal Pigment Epithelium Alterations and Chorioretinal Vascular Network Analyses in Patients under Treatment with BRAF/MEK Inhibitor for Different Malignancies: A Pilot Study
    Giuseppe Fasolino et al, 2023, Journal of Clinical Medicine CrossRef
  16. MEK inhibitor-associated retinopathy (MEKAR) in metastatic melanoma: Long-term ophthalmic effects
    U. Urner-Bloch et al, 2016, European Journal of Cancer CrossRef
  17. Trametinib-associated Hyponatremia in a Child With Low-grade Glioma is Not Seen Following Treatment With Alternative MEK Inhibitor
    Margot A. Lazow et al, 2021, Journal of Pediatric Hematology/Oncology CrossRef
  18. MEK inhibitors: a new class of chemotherapeutic agents with ocular toxicity
    K E Duncan et al, 2015, Eye CrossRef
  19. Ocular changes in metastatic melanoma patients treated with MEK inhibitor cobimetinib and BRAF inhibitor vemurafenib
    Ana Ursula Gavric et al, 2018, Radiology and Oncology CrossRef
  20. ACUTE EXUDATIVE POLYMORPHOUS VITELLIFORM MACULOPATHY ASSOCIATED WITH PRIMARY EPSTEIN–BARR VIRUS INFECTION
    Anna M. Lentzsch et al, 2022, RETINAL Cases & Brief Reports CrossRef
  21. Diagnostic and Therapeutic Challenges
    Céline Faure et al, 2016, Retina CrossRef
  22. Retinal Toxicity Associated With MEK Inhibitor Use for Metastatic Cancer: A Rising Trend in Ophthalmology
    Daniel P. Nolan et al, 2016, Ophthalmic Surgery, Lasers and Imaging Retina CrossRef
  23. Modification of aquaporin expression in response to fenretinide‐induced transdifferentiation of ARPE‐19 cells into neuronal‐like cells
    Dany Salik et al, 2016, Acta Ophthalmologica CrossRef
  24. LYTAK1 attenuates proliferation of retinal pigment epithelial cells through TGF‑β‑mediated epithelial‑mesenchymal transition via the ERK/AKT signaling pathway
    Zhen Chen et al, 2017, Experimental and Therapeutic Medicine CrossRef
  25. Silk lutein extract and its combination with vitamin E reduce UVB-mediated oxidative damage to retinal pigment epithelial cells
    Sathid Aimjongjun et al, 2013, Journal of Photochemistry and Photobiology B: Biology CrossRef
  26. Ultraviolet B Downregulated Aquaporin 1 Expression via the MEK/ERK pathway in the Dermal Fibroblasts
    Won-Oh Kim et al, 2020, Annals of Dermatology CrossRef
  27. Risk of Ophthalmic Adverse Effects in Patients Treated with MEK Inhibitors: A Systematic Review and Meta-Analysis
    Carlos Alves et al, 2017, Ophthalmic Research CrossRef
  28. Rapamycin sensitive mTOR activation mediates nerve growth factor (NGF) induced cell migration and pro-survival effects against hydrogen peroxide in retinal pigment epithelial cells
    Guo-Fan Cao et al, 2011, Biochemical and Biophysical Research Communications CrossRef
  29. Aquaporin-1: a potential membrane channel for facilitating the adaptability of rabbit nucleus pulposus cells to an extracellular matrix environment
    Feng Wang et al, 2011, Journal of Orthopaedic Science CrossRef
  30. Clinical features of serous retinopathy observed with cobimetinib in patients with BRAF-mutated melanoma treated in the randomized coBRIM study
    Luis de la Cruz-Merino et al, 2017, Journal of Translational Medicine CrossRef
  31. Involvement of NYD‐SP15 in growth and oxidative‐stress responses of ARPE‐19
    Yidan Xu et al, 2019, Journal of Cellular Biochemistry CrossRef
  32. Wild chrysanthemum extract prevents UVB radiation-induced acute cell death and photoaging
    Sujiao Sun et al, 2016, Cytotechnology CrossRef
  33. Ocular toxicities of MEK inhibitors and other targeted therapies
    N. Stjepanovic et al, 2016, Annals of Oncology CrossRef
  34. Trametinib Toxicities in Patients With Low-grade Gliomas and Diabetes Insipidus: Related Findings?
    Grace Egan et al, 2020, Journal of Pediatric Hematology/Oncology CrossRef
  35. PBEF promotes the apoptosis of pulmonary microvascular endothelial cells and regulates the expression of inflammatory factors and AQP1 through the MAPK pathways
    GUANG-FENG MING et al, 2015, International Journal of Molecular Medicine CrossRef
  36. Early Optical Coherence Tomography Signs of Erdafitinib-Induced Retinopathy
    Carson W Ercanbrack et al, 2024, Cureus CrossRef
  37. Malignant melanoma with retinal detachment due to combination therapy of dabrafenib and trametinib : A case report
    Arisa KISHI et al, 2020, Skin Cancer CrossRef
  38. Oral Selumetinib Does Not Negatively Impact Photoreceptor Survival in Murine Experimental Retinal Detachment
    Colleen M. Cebulla et al, 2019, Investigative Opthalmology & Visual Science CrossRef
  39. Ocular Toxicity Profile of ST-162 and ST-168 as Novel Bifunctional MEK/PI3K Inhibitors
    Andrew Smith et al, 2018, Journal of Ocular Pharmacology and Therapeutics CrossRef
  40. Choriocapillaris Assessment In Patients Under Mek-Inhibitor Therapy For Cutaneous Melanoma: An Optical Coherence Tomography Angiography Study
    Giuseppe Fasolino et al, 2021, Seminars in Ophthalmology CrossRef
  41. OCULAR ADVERSE EVENTS ASSOCIATED WITH MEK INHIBITORS
    Silvia Méndez-Martínez et al, 2019, Retina CrossRef
  42. Two cases of acute‐onset cystoid macular edema and serous retinal detachment associated with combined use of encorafenib and binimetinib for advanced melanoma: A possible confounding risk for drug intolerance
    Takumi Hasegawa et al, 2023, Journal of Cutaneous Immunology and Allergy CrossRef
  43. Mechanisms of macular edema: Beyond the surface
    Alejandra Daruich et al, 2018, Progress in Retinal and Eye Research CrossRef
  44. Loss of MAPK Pathway Activation in Post-Mitotic Retinal Cells as Mechanism in MEK Inhibition-Related Retinopathy in Cancer Patients
    Elon H. C. van Dijk et al, 2016, Medicine CrossRef
  45. Cobimetinib‑/Vemurafenib-assoziierte bilaterale seröse Retinopathie: ein Fallbericht
    Gregor Kastl, 2019, Der Ophthalmologe CrossRef
  46. Age-Related Changes in Male Skin: Quantitative Evaluation of One Hundred and Fifty Male Subjects
    S. Luebberding et al, 2014, Skin Pharmacology and Physiology CrossRef
  47. Toxicité oculaire des thérapies ciblées anti-MEK et anti-BRAF dans le traitement des mélanomes cutanés métastatiques
    E. Fauviaux et al, 2022, Journal Français d'Ophtalmologie CrossRef
  48. FREQUENT SUBCLINICAL MACULAR CHANGES IN COMBINED BRAF/MEK INHIBITION WITH HIGH-DOSE HYDROXYCHLOROQUINE AS TREATMENT FOR ADVANCED METASTATIC BRAF MUTANT MELANOMA
    Akosua A. Nti et al, 2019, Retina CrossRef
  49. Friends or Foes? An Update on Retinal Toxicities of Systemic Medications
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  50. Fibroblast Growth Factor Receptor Inhibitor–Associated Multifocal Serous Retinal Detachments: A Case Report
    Diana H. Kim et al, 2022, Journal of VitreoRetinal Diseases CrossRef
  51. Clinical and Morphologic Characteristics of MEK Inhibitor–Associated Retinopathy
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  52. Sun‐induced changes of stratum corneum hydration vary with age and gender in a normal Chinese population
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  53. Characterization of Serous Retinopathy Associated with Cobimetinib: Integrated Safety Analysis of Four Studies
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  54. Choriorétinopathie séreuse multifocale secondaire à l’utilisation des inhibiteurs MEK : illustration et exemple de prise en charge à travers 2 cas
    A. Coutu et al, 2016, Journal Français d'Ophtalmologie CrossRef
  55. Tumor necrosis factor-alpha (TNF-α)-mediated in vitro human retinal pigment epithelial (RPE) cell migration mainly requires Akt/mTOR complex 1 (mTORC1), but not mTOR complex 2 (mTORC2) signaling
    Yuan Liu et al, 2012, European Journal of Cell Biology CrossRef
  56. Die seröse Retinopathie: eine wichtige Nebenwirkung in der Tumorbehandlung
    I. Lüdeke et al, 2017, Der Ophthalmologe CrossRef
  57. Inhaled gold nanoparticles cause cerebral edema and upregulate endothelial aquaporin 1 expression, involving caveolin 1 dependent repression of extracellular regulated protein kinase activity
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