1. Co-Mutation of FAT3 and LRP1B in Lung Adenocarcinoma Defines a Unique Subset Correlated With the Efficacy of Immunotherapy
    Mingyu Zhu et al, 2022, Frontiers in Immunology CrossRef
  2. Single-cell sequencing analysis and transcriptome analysis constructed the macrophage related gene-related signature in lung adenocarcinoma and verified by an independent cohort
    Ruixia Li et al, 2022, Genomics CrossRef
  3. Chromosome 5
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  4. Molecular and Clinical Spectrum of Primary Hyperparathyroidism
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  5. ALPK1 hotspot mutation as a driver of human spiradenoma and spiradenocarcinoma
    Mamunur Rashid et al, 2019, Nature Communications CrossRef
  6. Cell Line-, Protein-, and Sialoglycosite-Specific Control of Flux-Based Sialylation in Human Breast Cells: Implications for Cancer Progression
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  7. Facioscapulohumeral Muscular Dystrophy
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  8. A novel ferroptosis phenotype‐related clinical‐molecular prognostic signature for hepatocellular carcinoma
    Tuo Deng et al, 2021, Journal of Cellular and Molecular Medicine CrossRef
  9. FAT1: a potential target for monoclonal antibody therapy in colon cancer
    Piero Pileri et al, 2016, British Journal of Cancer CrossRef
  10. Whole-exome Sequencing Reveals New Potential Susceptibility Genes for Japanese Familial Pancreatic Cancer
    Erina Takai et al, 2022, Annals of Surgery CrossRef
  11. Systemic analysis of the expression levels and prognosis of breast cancer-related cadherins
    Mingfei Xu et al, 2021, Experimental Biology and Medicine CrossRef
  12. Regulation and function of the atypical cadherin FAT1 in hepatocellular carcinoma
    Daniela Valletta et al, 2014, Carcinogenesis CrossRef
  13. A step towards personalizing next line therapy for resected pancreatic and related cancer patients: A single institution's experience
    Cinthya Y. Lowder et al, 2020, Surgical Oncology CrossRef
  14. Upregulation of Atypical Cadherin FAT1 Promotes an Immunosuppressive Tumor Microenvironment via TGF-β
    Khushboo Irshad et al, 2022, Frontiers in Immunology CrossRef
  15. The atypical cadherin Dachsous1 localizes to the base of the ciliary apparatus in airway epithelia
    Cécile Dau et al, 2016, Biochemical and Biophysical Research Communications CrossRef
  16. The possible FAT1‐mediated apoptotic pathways in porcine cumulus cells
    Xinhui Wu et al, 2017, Cell Biology International CrossRef
  17. FAT4 hypermethylation and grade dependent downregulation in gastric adenocarcinoma
    Maryam Pilehchian Langroudi et al, 2017, Journal of Cell Communication and Signaling CrossRef
  18. FAT1 somatic mutations in head and neck carcinoma are associated with tumor progression and survival
    Shu-Chun Lin et al, 2018, Carcinogenesis CrossRef
  19. FAT1 biallelic truncating mutation causes a non-syndromic proteinuria in a child
    Rini Rossanti et al, 2021, CEN Case Reports CrossRef
  20. Fetal nuchal edema and developmental anomalies caused by gene mutations in mice
    Akira Sugiyama et al, 2022, Frontiers in Cell and Developmental Biology CrossRef
  21. WNT receptor signalling in lung physiology and pathology
    Wioletta Skronska-Wasek et al, 2018, Pharmacology & Therapeutics CrossRef
  22. Next-generation Sequencing in the Management of Gastric and Esophageal Cancers
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  23. Reciprocal fine-tuning of progesterone and prolactin-regulated gene expression in breast cancer cells
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  24. Exploring prognostic indicators in the pathological images of hepatocellular carcinoma based on deep learning
    Jie-Yi Shi et al, 2021, Gut CrossRef
  25. Overexpression of the giant FAT1 cadherin gene and its prognostic significance in de novo acute leukaemia patients
    Rania M. Gawdat et al, 2017, Comparative Clinical Pathology CrossRef
  26. The molecular landscape of the University of Michigan laryngeal squamous cell carcinoma cell line panel
    Jacqueline E. Mann et al, 2019, Head & Neck CrossRef
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    Ting Lan et al, 2022, Frontiers in Oncology CrossRef
  28. Integrated Analysis of Mutation Data from Various Sources Identifies Key Genes and Signaling Pathways in Hepatocellular Carcinoma
    Yuannv Zhang et al, 2014, PLoS ONE CrossRef
  29. Prognostic and Immunological Role of FAT Family Genes in Non-Small Cell Lung Cancer
    Zhenxing Feng et al, 2022, Cancer Control CrossRef
  30. Mutation in the Drosophila melanogaster adenosine receptor gene selectively decreases the mosaic hyperplastic epithelial outgrowth rates in wts or dco heterozygous flies
    Roman Sidorov et al, 2015, Purinergic Signalling CrossRef
  31. Dynamic gene expression by putative hair-cell progenitors during regeneration in the zebrafish lateral line
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  32. miR-30d-5p represses the proliferation, migration, and invasion of lung squamous cell carcinoma via targetingDBF4
    Yitian Qi et al, 2021, Journal of Environmental Science and Health, Part C CrossRef
  33. Revealing the transcriptional heterogeneity of organ‐specific metastasis in human gastric cancer using single‐cell RNA Sequencing
    Haiping Jiang et al, 2022, Clinical and Translational Medicine CrossRef
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  35. Investigating the prognostic value of mTORC1 signaling in bladder cancer via bioinformatics evaluation
    Xin Yu et al, 2023, Scientific Reports CrossRef
  36. Predictive modeling of gene mutations for the survival outcomes of epithelial ovarian cancer patients
    Mirielle C. Ma et al, 2024, PLOS ONE CrossRef
  37. Predictive capacity of FAT1 transcriptional expression in patients with head and neck squamous cell carcinomas treated with radiotherapy
    Xavier León et al, 2023, Acta Otorrinolaringologica (English Edition) CrossRef
  38. Targeting FAT1 Inhibits Carcinogenesis, Induces Oxidative Stress and Enhances Cisplatin Sensitivity through Deregulation of LRP5/WNT2/GSS Signaling Axis in Oral Squamous Cell Carcinoma
    Tung-Nien Hsu et al, 2019, Cancers CrossRef
  39. FAT4 activation inhibits epithelial-mesenchymal transition (EMT) by promoting autophagy in H2228/Cer cells
    Yuying Yang et al, 2022, Medical Oncology CrossRef
  40. Transcriptomic profile analysis of brain inferior colliculus following acute hydrogen sulfide exposure
    Dong-Suk Kim et al, 2020, Toxicology CrossRef
  41. Inhibitory Mechanism of FAT4 Gene Expression in Response to Actin Dynamics during Src-Induced Carcinogenesis
    Takao Ito et al, 2015, PLOS ONE CrossRef
  42. A Population-Based Study of Four Genes Associated with Heroin Addiction in Han Chinese
    Yunxiao Li et al, 2016, PLOS ONE CrossRef
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    Akira Takemoto et al, 2021, Cancer Science CrossRef
  44. An Aggressive Presentation of Mantle Cell Lymphoma With Unique Molecular Features
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  45. Epigenetic inactivation of FAT4 contributes to gastric field cancerization
    Satoshi Yoshida et al, 2017, Gastric Cancer CrossRef
  46. Effect of FAT1 gene expression on the prognosis of medulloblastoma in children
    Jingzhe Yu et al, 2020, Medicine CrossRef
  47. Oncogenic LINC00857 recruits TFAP2C to elevate FAT1 expression in gastric cancer
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  48. Upregulation of mesothelial genes in ovarian carcinoma cells is associated with an unfavorable clinical outcome and the promotion of cancer cell adhesion
    Kaire Ojasalu et al, 2020, Molecular Oncology CrossRef
  49. The quest for ligands and binding partners of atypical cadherin FAT1
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  50. Novel Genetic Variants Associated with Chronic Kidney Disease Progression
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  51. Copy number variations and expression of MPDZ are prognostic biomarkers for clear cell renal cell carcinoma
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  52. The Expression of FAT1 is Associated with Overall Survival in Children with Medulloblastoma
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  53. Comparison of gene mutation spectra in younger and older Chinese acute myeloid leukemia patients and its prognostic value
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  54. Identification of New Genes Involved in Germline Predisposition to Early-Onset Gastric Cancer
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  55. Disseminated Medulloblastoma in a Child with Germline BRCA2 6174delT Mutation and without Fanconi Anemia
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  56. Clinicopathologic features and genomic analysis of pulmonary blastomatoid carcinosarcoma
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  59. Planar Cell Polarity Gene Mutations in Autism Spectrum Disorder, Intellectual Disabilities, and Related Deletion/Duplication Syndromes
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  60. SpidermiR: An R/Bioconductor Package for Integrative Analysis with miRNA Data
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  61. FAT1 expression and mutations in adult acute lymphoblastic leukemia
    M Neumann et al, 2014, Blood Cancer Journal CrossRef
  62. Personalized prediction of genes with tumor-causing somatic mutations based on multi-modal deep Boltzmann machine
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  63. Linc00887 suppresses tumorigenesis of cervical cancer through regulating the miR-454-3p/FRMD6-Hippo axis
    Pei Li et al, 2021, Cancer Cell International CrossRef
  64. Recurrent somatic mutations of FAT family cadherins induce an aggressive phenotype and poor prognosis in anaplastic large cell lymphoma
    Matteo Villa et al, 2024, British Journal of Cancer CrossRef
  65. Yes-associated protein 1 (YAP1) promotes human gallbladder tumor growth via activation of the AXL/MAPK pathway
    Maolan Li et al, 2014, Cancer Letters CrossRef
  66. Identification of the atypical cadherin FAT1 as a novel glypican-3 interacting protein in liver cancer cells
    Panpan Meng et al, 2021, Scientific Reports CrossRef
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    Su Il Kim et al, 2022, Molecular Oncology CrossRef
  68. Neuron‐specific knockdown of the Drosophila fat induces reduction of life span, deficient locomotive ability, shortening of motoneuron terminal branches and defects in axonal targeting
    Aya Nakamura et al, 2017, Genes to Cells CrossRef
  69. A pan-cancer analysis of FAT atypical cadherin 4 (FAT4) in human tumors
    Weili Mao et al, 2022, Frontiers in Public Health CrossRef
  70. The FABRIC Cancer Portal: A Ranked Catalogue of Gene Selection in Tumors Over the Human Coding Genome
    Guy Kelman et al, 2021, Cancer Research CrossRef
  71. To be, or not to be: the dilemma of immunotherapy for non-small cell lung cancer harboring various driver mutations
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  72. Comprehensive characterization of viral integrations and genomic aberrations in HBV‐infected intrahepatic cholangiocarcinomas
    Jihyun An et al, 2022, Hepatology CrossRef
  73. Dissecting the role of polarity regulators in cancer through the use of mouse models
    Nathan J Gödde et al, 2014, Experimental Cell Research CrossRef
  74. Proteomic Dissection of Nanotopography-Sensitive Mechanotransductive Signaling Hubs that Foster Neuronal Differentiation in PC12 Cells
    Elisa Maffioli et al, 2018, Frontiers in Cellular Neuroscience CrossRef
  75. FAT4 silencing promotes epithelial-to-mesenchymal transition and invasion via regulation of YAP and β-catenin activity in ovarian cancer
    Shika Hanif Malgundkar et al, 2020, BMC Cancer CrossRef
  76. Integrated genomic analysis reveals aberrations in WNT signaling in germ cell tumors of childhood and adolescence
    Lin Xu et al, 2023, Nature Communications CrossRef
  77. Recursive Random Lasso (RRLasso) for Identifying Anti-Cancer Drug Targets
    Heewon Park et al, 2015, PLOS ONE CrossRef
  78. Heterogeneous addiction to transforming growth factor‐beta signalling in recessive dystrophic epidermolysis bullosa‐associated cutaneous squamous cell carcinoma*
    J.H.S. Dayal et al, 2021, British Journal of Dermatology CrossRef
  79. Loss of FAT Atypical Cadherin 4 Expression Is Associated with High Pathologic T Stage in Radically Resected Gastric Cancer
    Hae Yoen Jung et al, 2015, Journal of Gastric Cancer CrossRef
  80. Candidate driver genes involved in genome maintenance and DNA repair in Sézary syndrome
    Wesley J. Woollard et al, 2016, Blood CrossRef
  81. MiR-93-5p promotes gastric cancer-cell progression via inactivation of the Hippo signaling pathway
    Li Li et al, 2018, Gene CrossRef
  82. Molecular mechanisms underlying the regulation of tumour suppressor genes in lung cancer
    Jia Yee Lee et al, 2024, Biomedicine & Pharmacotherapy CrossRef
  83. Genomic Profiles of a Patient of Pulmonary Hepatoid Adenocarcinoma With High AFP Level: A Case Report
    Jinglin Li et al, 2019, Frontiers in Oncology CrossRef
  84. Novel ASAP1‐USP6, FAT1‐USP6, SAR1A‐USP6, and TNC‐USP6 fusions in primary aneurysmal bone cyst
    Daja Šekoranja et al, 2020, Genes, Chromosomes and Cancer CrossRef
  85. Low FAT4 expression is associated with a poor prognosis in gastric cancer patients
    Xiaoting Jiang et al, 2018, Oncotarget CrossRef
  86. Discovery of dearomatized isoprenylated acylphloroglucinols with colon tumor suppressive activities in mice via inhibiting NFκB-FAT1-PDCD4 signaling activation
    Na-Na Jiang et al, 2022, European Journal of Medicinal Chemistry CrossRef
  87. Immunohistochemical localization of a proto‐cadherin fat tumour‐suppressor homolog in the regenerating tail of lizard suggests a role in apical growth control
    Lorenzo Alibardi, 2020, Acta Zoologica CrossRef
  88. Does SCA45 Cause Very Late-Onset Pure Cerebellar Ataxia?
    Thiago Y. Tonholo Silva et al, 2021, Neurology Genetics CrossRef
  89. SARS-CoV-2 Kerala Isolate Spike Protein Induces Cancer Proliferating Markers for Lung and Breast Cancer: An In Silico Approach
    Stalin Selvaraj et al, 2022, Coronaviruses CrossRef
  90. Mutations and Copy Number Abnormalities of Hippo Pathway Components in Human Cancers
    Zhengjin He et al, 2021, Frontiers in Cell and Developmental Biology CrossRef
  91. Pan-Cancer Survey of Tumor Mass Dormancy and Underlying Mutational Processes
    Anna Julia Wiecek et al, 2021, Frontiers in Cell and Developmental Biology CrossRef
  92. From driver genes to gene families: A computational analysis of oncogenic mutations and ubiquitination anomalies in hepatocellular carcinoma
    Meng Wang et al, 2024, Computational Biology and Chemistry CrossRef
  93. A synthetic planar cell polarity system reveals localized feedback on Fat4-Ds1 complexes
    Olga Loza et al, 2017, eLife CrossRef
  94. Whole-exome sequencing and bioinformatics analysis of a case of non-alpha-fetoprotein-elevated lung hepatoid adenocarcinoma
    Yao Yao et al, 2022, Frontiers in Pharmacology CrossRef
  95. Comprehensive Genomic Profiling Identifies FAT1 as a Negative Regulator of EMT, CTCs, and Metastasis of Hepatocellular Carcinoma
    Zi-Li Huang et al, 2023, Journal of Hepatocellular Carcinoma CrossRef
  96. Capacidad predictiva de la expresión transcripcional de FAT1 en pacientes con carcinomas escamosos de cabeza y cuello tratados con radioterapia
    Xavier León et al, 2023, Acta Otorrinolaringológica Española CrossRef
  97. Genomic and Transcriptomic Characterization of Sporadic Medullary Thyroid Carcinoma
    Ning Qu et al, 2020, Thyroid CrossRef
  98. Exome and Tissue-Associated Microbiota as Predictive Markers of Response to Neoadjuvant Treatment in Locally Advanced Rectal Cancer
    Isabella Kuniko T. M. Takenaka et al, 2022, Frontiers in Oncology CrossRef
  99. Somatic Mutation of FAT Family Genes Implicated Superior Prognosis in Patients With Stomach Adenocarcinoma
    Qingjun Wang et al, 2022, Frontiers in Medicine CrossRef
  100. The novel FAT4 activator jujuboside A suppresses NSCLC tumorigenesis by activating HIPPO signaling and inhibiting YAP nuclear translocation
    Wensheng Wang et al, 2021, Pharmacological Research CrossRef
  101. The role of PKP1 in tumor progression in melanoma: Analysis of a cell adhesion‐related model
    Chao Yue et al, 2024, Environmental Toxicology CrossRef
  102. Integrated analysis of lncRNAs and mRNAs by RNA-Seq in secondary hair follicle development and cycling (anagen, catagen and telogen) of Jiangnan cashmere goat (Capra hircus)
    Cuiling Wu et al, 2022, BMC Veterinary Research CrossRef
  103. Fat3 and Ena/VASP proteins influence the emergence of asymmetric cell morphology in the developing retina
    Alexandra Krol et al, 2016, Development CrossRef
  104. Targeted genomic investigations in a population-based cohort of mantle cell lymphoma reveal novel clinically relevant targets
    Joana M. Rodrigues et al, 2021, Leukemia & Lymphoma CrossRef
  105. Prognostic and Therapeutic Implications of Cell Division Cycle 20 Homolog in Breast Cancer
    Samia S. Messeha et al, 2024, Cancers CrossRef
  106. Recurrent gene mutations detected in canine mast cell tumours by next generation sequencing
    Miluse Vozdova et al, 2020, Veterinary and Comparative Oncology CrossRef
  107. A transcriptional signature detects homologous recombination deficiency in pancreatic cancer at the individual level
    Shuping Zhuang et al, 2021, Molecular Therapy - Nucleic Acids CrossRef
  108. YAP Subcellular Localization and Hippo Pathway Transcriptome Analysis in Pediatric Hepatocellular Carcinoma
    Michael J. LaQuaglia et al, 2016, Scientific Reports CrossRef
  109. Somatic mutations in oral squamous cell carcinomas in 98 Japanese patients and their clinical implications
    Yuko Osawa et al, 2021, Cancer Treatment and Research Communications CrossRef
  110. Identification of mechanosensitive genes during skeletal development: alteration of genes associated with cytoskeletal rearrangement and cell signalling pathways
    Rebecca A Rolfe et al, 2014, BMC Genomics CrossRef
  111. Whole exome sequencing reveals recurrent mutations in BRCA2 and FAT genes in acinar cell carcinomas of the pancreas
    Toru Furukawa et al, 2015, Scientific Reports CrossRef
  112. Whole-exome mutational landscape of neuroendocrine carcinomas of the gallbladder
    Fatao Liu et al, 2021, Signal Transduction and Targeted Therapy CrossRef
  113. Mutational interactions define novel cancer subgroups
    Jack Kuipers et al, 2018, Nature Communications CrossRef
  114. The transcriptional landscape and biomarker potential of circular RNAs in prostate cancer
    Emma Bollmann Hansen et al, 2022, Genome Medicine CrossRef
  115. Machine learning and multi-omics data reveal driver gene-based molecular subtypes in hepatocellular carcinoma for precision treatment
    Meng Wang et al, 2024, PLOS Computational Biology CrossRef
  116. FAT4 Fine-Tunes Kidney Development by Regulating RET Signaling
    Hongtao Zhang et al, 2019, Developmental Cell CrossRef
  117. Antitumor immunity and prognosis value elicited by FAT3 and LRP1B co-mutation in endometrial cancer
    Zhansheng Jiang et al, 2024, Gynecologic Oncology CrossRef
  118. Expanding the Spectrum of FAT1 Nephropathies by Novel Mutations That Affect Hippo Signaling
    Francesca Fabretti et al, 2021, Kidney International Reports CrossRef
  119. The Role of Human Papilloma Virus in Dictating Outcomes in Head and Neck Squamous Cell Carcinoma
    Shane Brennan et al, 2021, Frontiers in Molecular Biosciences CrossRef
  120. Activating Mutations in PTPN3 Promote Cholangiocarcinoma Cell Proliferation and Migration and Are Associated With Tumor Recurrence in Patients
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  121. A novel mutation of the FAT2 gene in spinal meningioma
    Genshu Tate et al, 2016, Oncology Letters CrossRef
  122. The critical role of the Hippo signaling pathway in kidney diseases
    Yuting Sun et al, 2022, Frontiers in Pharmacology CrossRef
  123. Genomic characterization of sarcomatoid transformation in clear cell renal cell carcinoma
    Mark Bi et al, 2016, Proceedings of the National Academy of Sciences CrossRef
  124. Hepatoid Adenocarcinoma of the Lung: A Review of the Most Updated Literature and a Presentation of Three Cases
    Alessandro Bonis et al, 2023, Journal of Clinical Medicine CrossRef
  125. FAT4 Mutation is Related to Tumor Mutation Burden and Favorable Prognosis in Gastric Cancer
    Qingqing Li et al, 2024, Current Genomics CrossRef
  126. Endothelial FAT1 inhibits angiogenesis by controlling YAP/TAZ protein degradation via E3 ligase MIB2
    Rui Li et al, 2023, Nature Communications CrossRef
  127. YAP is closely correlated with castration-resistant prostate cancer, and downregulation of YAP reduces proliferation and induces apoptosis of PC-3 cells
    XIA SHENG et al, 2015, Molecular Medicine Reports CrossRef
  128. Inactivation of Hippo pathway characterizes a poor-prognosis subtype of esophageal cancer
    Zihang Mai et al, 2022, JCI Insight CrossRef
  129. FAT4 expression in peripheral blood mononuclear cells is associated with prognosis and immune cell infiltration in hepatocellular carcinoma
    Jing Li et al, 2023, Scientific Reports CrossRef
  130. Reduced SERCA Function Preferentially Affects Wnt Signaling by Retaining E-Cadherin in the Endoplasmic Reticulum
    Annabelle Suisse et al, 2019, Cell Reports CrossRef
  131. Investigation of BRCA1 methylation and FAT3 mutation as a potential biomarker in ovarian cancer samples
    Manish Pratap Singh et al, 2022, Human Gene CrossRef
  132. Inferring the progression of multifocal liver cancer from spatial and temporal genomic heterogeneity
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  133. The architecture of clonal expansions in morphologically normal tissue from cancerous and non-cancerous prostates
    Claudia Buhigas et al, 2022, Molecular Cancer CrossRef
  134. FAT1 prevents epithelial mesenchymal transition (EMT) via MAPK/ERK signaling pathway in esophageal squamous cell cancer
    Xiaoling Hu et al, 2017, Cancer Letters CrossRef
  135. A urinary microRNA signature can predict the presence of bladder urothelial carcinoma in patients undergoing surveillance
    Nikhil Sapre et al, 2016, British Journal of Cancer CrossRef
  136. Genomic Hippo Pathway Alterations and Persistent YAP/TAZ Activation: New Hallmarks in Head and Neck Cancer
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  138. Exploring potential molecular resistance and clonal evolution in advanced HER2-positive gastric cancer under trastuzumab therapy
    Qi Xu et al, 2023, Oncogenesis CrossRef
  139. Gastric adenocarcinoma
    Jaffer A. Ajani et al, 2017, Nature Reviews Disease Primers CrossRef
  140. A comprehensive genomic pan-cancer classification using The Cancer Genome Atlas gene expression data
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  142. A platform of functional studies of ESCC-associated gene mutations identifies the roles of TGFBR2 in ESCC progression and metastasis
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  143. Aberrant activation, nuclear localization, and phosphorylation of yes-associated protein-1 in the embryonic kidney and Wilms tumor
    Andrew J. Murphy et al, 2014, Pediatric Blood & Cancer CrossRef
  144. Loss of FAT1 during the progression from DCIS to IDC and predict poor clinical outcome in breast cancer
    Li Wang et al, 2016, Experimental and Molecular Pathology CrossRef
  145. Novel genetic alterations in liver cancer distinguish distinct clinical outcomes and combination immunotherapy responses
    Yizhou Wang et al, 2024, Frontiers in Pharmacology CrossRef
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    Haifeng Zhuang et al, 2020, PeerJ CrossRef
  147. Identification of the RP11-21C4.1/SVEP1 gene pair associated with FAT2 mutations as a potential biomarker in gastric cancer
    Lingshan Zhou et al, 2021, Bioengineered CrossRef
  148. Mutant Presenilin 1 Dysregulates Exosomal Proteome Cargo Produced by Human-Induced Pluripotent Stem Cell Neurons
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  149. Whole-Exome Sequencing Revealed the Mutational Profiles of Primary Central Nervous System Lymphoma
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