1. Anti-Cancer Stem-like Cell Compounds in Clinical Development – An Overview and Critical Appraisal
   Fabrizio Marcucci et al, 2016, Front. Oncol. CrossRef
2. Multiple regulation pathways and pivotal biological functions of STAT3 in cancer.
   Jie Yuan et al, 2015, Sci Rep CrossRef
3. CCR7 Regulates Cell Migration and Invasion through JAK2/STAT3 in Metastatic Squamous Cell Carcinoma of the Head and Neck
   Fa-Yu Liu et al, 2014, BioMed Research International CrossRef
4. MicroRNA-214 acts as a potential oncogene in breast cancer by targeting the PTEN-PI3K/Akt signaling pathway
   FANG WANG et al, 2016 CrossRef
5. Selective FGFR inhibitor BGJ398 inhibits phosphorylation of AKT and STAT3 and induces cytotoxicity in sphere-cultured ovarian cancer cells
   Hwa Jun Cha et al, 2017 CrossRef
6. Evasion of anti-growth signaling: A key step in tumorigenesis and potential target for treatment and prophylaxis by natural compounds
   A.R.M. Ruhul Amin et al, 2015, Seminars in Cancer Biology CrossRef
7. Activation of peroxisome proliferator-activated receptor γ ameliorates monocrotaline-induced pulmonary arterial hypertension in rats
   XINMING XIE et al, 2015 CrossRef
8. Silencing of RegIV by shRNA causes the loss of stemness properties of cancer stem cells in MKN45 gastric cancer cells
   WEI ZHOU et al, 2013 CrossRef
9. PIWI family emerging as a decisive factor of cell fate: An overview
   Murugavel Ponnusamy et al, 2017, European Journal of Cell Biology CrossRef
10. PTEN drives Th17 cell differentiation by preventing IL-2 production
    Hyeong Su Kim et al, 2017, J. Exp. Med. CrossRef
11. C6 glioma-conditioned medium induces malignant transformation of mesenchymal stem cells: Possible role of S100B/RAGE pathway
    Bin Tan et al, 2017, Biochemical and Biophysical Research Communications CrossRef
12. Arctigenin induced gallbladder cancer senescence through modulating epidermal growth factor receptor pathway
    Mingdi Zhang et al, 2017, Tumour Biol. CrossRef
13. Morusin Induces TRAIL Sensitization by Regulating EGFR and DR5 in Human Glioblastoma Cells
    Dain Park et al, 2016, J. Nat. Prod. CrossRef
14. miR-148a-3p overexpression contributes to glomerular cell proliferation by targeting PTEN in lupus nephritis
    Liu Qingjuan et al, 2016, American Journal of Physiology-Cell Physiology CrossRef
15. The PTEN/PI3K/Akt signaling pathway mediates HMGB1-induced cell proliferation by regulating the NF-κB/cyclin D1 pathway in mouse mesangial cells
    Xiao-Juan Feng et al, 2014, American Journal of Physiology-Cell Physiology CrossRef
16. Overexpression of the Transmembrane Protein IQGAP3 Is Associated with Poor Survival of Patients with Gastric Cancer
    Naohide Oue et al, 2017, Pathobiology CrossRef
17. Reduced expression levels of PTEN are associated with decreased sensitivity of HCC827 cells to icotinib
    Yang Zhai et al, 2017 CrossRef
18. Biomimetic models to examine microenvironmental regulation of glioblastoma stem cells
    Pinaki S. Nakod et al, 2018, Cancer Letters CrossRef
19. Cytokeratin 19 (KRT19) has a Role in the Reprogramming of Cancer Stem Cell-Like Cells to Less Aggressive and More Drug-Sensitive Cells
    Subbroto Saha et al, 2018, IJMS CrossRef
20. IL-1β promotes the nuclear translocaiton of S100A4 protein in gastric cancer cells MGC803 and the cell's stem-like properties through PI3K pathway
    Aiwen Yu et al, 2018, J. Cell. Biochem. CrossRef
21. Microcystin-LR promotes migration via the cooperation between microRNA-221/PTEN and STAT3 signal pathway in colon cancer cell line DLD-1
    Yan Ren et al, 2019, Ecotoxicology and Environmental Safety CrossRef
22. Loss of PTEN induces lung fibrosis via alveolar epithelial cell senescence depending on NF‐κB activation
    Yaqiong Tian et al, 2018, Aging Cell CrossRef
23. Overexpression of the cancer stem cell marker CD133 confers a poor prognosis in invasive breast cancer.
    Chitra Joseph et al, 2019, Breast Cancer Res Treat CrossRef
24. Deregulated Gab2 phosphorylation mediates aberrant AKT and STAT3 signaling upon PIK3R1 loss in ovarian cancer.
    Xinran Li et al, 2019, Nat Commun CrossRef
25. Combined Inhibition of HDAC and EGFR Reduces Viability and Proliferation and Enhances STAT3 mRNA Expression in Glioblastoma Cells
    Marienela Buendia Duque et al, 2019, J Mol Neurosci CrossRef
26. α-Mangostin suppresses human gastric adenocarcinoma cells in vitro via blockade of Stat3 signaling pathway
    Tao Shan et al, 2014, Acta Pharmacol Sin CrossRef
27. MiR-202-5p/PTEN mediates doxorubicin-resistance of breast cancer cells via PI3K/Akt signaling pathway
    Tao Liu et al, 2019, Cancer Biology & Therapy CrossRef
28. KRT19 directly interacts with β-catenin/RAC1 complex to regulate NUMB-dependent NOTCH signaling pathway and breast cancer properties
    S K Saha et al, 2017, Oncogene CrossRef
29. PTEN status is a crucial determinant of the functional outcome of combined MEK and mTOR inhibition in cancer
    Michele Milella et al, 2017, Sci Rep CrossRef
30. Cryptotanshinone inhibits human glioma cell proliferation in vitro and in vivo through SHP-2-dependent inhibition of STAT3 activation
    Liang Lu et al, 2017, Cell Death Dis CrossRef
31. Alterations in Wnt- and/or STAT3 signaling pathways and the immune microenvironment during metastatic progression
    S. J. Kim et al, 2019, Oncogene CrossRef
32. Identification of Secreted Phosphoprotein 1 (SPP1) as a Prognostic Factor in Lower-Grade Gliomas
    Jiawei Chen et al, 2019, World Neurosurgery CrossRef
33. Casticin suppresses self-renewal and invasion of lung cancer stem-like cells from A549 cells through down-regulation of pAkt
    F. Liu et al, 2014, Acta Biochimica et Biophysica Sinica CrossRef
34. Melittin Restores PTEN Expression by Down-Regulating HDAC2 in Human Hepatocelluar Carcinoma HepG2 Cells
    Hui Zhang et al, 2014, PLoS ONE CrossRef
35. The emerging role of tumor-suppressive microRNA-218 in targeting glioblastoma stemness
    Xingchun Gao et al, 2014, Cancer Letters CrossRef
36. Roles of PTEN (Phosphatase and Tensin Homolog) in Gastric Cancer Development and Progression
    Wen-Ting Xu et al, 2014, Asian Pacific Journal of Cancer Prevention CrossRef
37. Pten Regulates Development and Lactation in the Mammary Glands of Dairy Cows
    Zhuoran Wang et al, 2014, PLoS ONE CrossRef
38. Fucoxanthin induces apoptosis in human cervical cancer cell line HeLa via PI3K/Akt pathway
    Guoliu Ye et al, 2014, Tumor Biol. CrossRef
39. Biological and clinical significance of cancer stem cell plasticity
    Yongyou Zhu et al, 2014, Clin Trans Med CrossRef
40. MicroRNA-106b promotes pituitary tumor cell proliferation and invasion through PI3K/AKT signaling pathway by targeting PTEN
    Kai Zhou et al, 2016, Tumor Biol. CrossRef
41. Signal transducer and activator of transcription 3 as a therapeutic target for cancer and the tumor microenvironment
    Byung-Hak Kim et al, 2016, Arch. Pharm. Res. CrossRef
42. MiR-200a acts as an oncogene in colorectal carcinoma by targeting PTEN
    Yijun Li et al, 2016, Experimental and Molecular Pathology CrossRef
43. The role of STAT3 in glioblastoma progression through dual influences on tumor cells and the immune microenvironment
    Nakho Chang et al, 2017, Molecular and Cellular Endocrinology CrossRef
44. An IKK/NF-κB Activation/p53 Deletion Sequence Drives Liver Carcinogenesis and Tumor Differentiation
    Michael Svinarenko et al, 2019, Cancers CrossRef
45. Role of PI3K/AKT Signaling Pathway in Proliferation, Migration and Odontogenic Differentiation of Human Dental Pulp Stem Cells
    Fang Zhang et al, 2020, J. hard tissue biol. CrossRef
46. Impact of STAT3 phosphorylation in glioblastoma stem cells radiosensitization and patient outcome
    Konstantin Masliantsev et al, 2018, Oncotarget CrossRef
47. BIS-mediated STAT3 stabilization regulates glioblastoma stem cell-like phenotypes
    Chang-Nim Im et al, 2016, Oncotarget CrossRef
48. 4-Methoxydalbergione suppresses growth and induces apoptosis in human osteosarcoma cells in vitro and in vivo xenograft model through down-regulation of the JAK2/STAT3 pathway
    Kyung-Ran Park et al, 2016, Oncotarget CrossRef
49. Identification of stem-like cells and clinical significance of candidate stem cell markers in gastric cancer
    Xiaowei Zhang et al, 2016, Oncotarget CrossRef
50. A microRNA signature profile in EBV+ diffuse large B-cell lymphoma of the elderly
    Tathiana Azevedo de Andrade et al, 2014, Oncotarget CrossRef
51. NLRP3 in human glioma is correlated with increased WHO grade, and regulates cellular proliferation, apoptosis and metastasis via epithelial-mesenchymal transition and the PTEN/AKT signaling pathway
    Xiao-Feng Yin et al, 2018, Int J Oncol CrossRef
52. Myristoylated alanine-rich C-kinase substrate effector domain phosphorylation regulates the growth and radiation sensitization of glioblastoma
    Nicholas Eustace et al, 2019, Int J Oncol CrossRef
53. miRNA‐216 knockdown has effects to suppress osteosarcoma via stimulating PTEN
    Ping Jiang et al, 2020, Food Sci Nutr CrossRef
54. MicroRNA miR-100 Decreases Glioblastoma Growth by Targeting SMARCA5 and ErbB3 in Tumor-Initiating Cells
    Bahauddeen M. Alrfaei et al, 2020, Technol Cancer Res Treat CrossRef
55. Mechanisms of cancer stem cell senescence: Current understanding and future perspectives
    Da‐Yong Zhang et al, 2021, Clin Exp Pharmacol Physiol CrossRef
56. Targeting the molecular mechanisms of glioma stem cell resistance to chemotherapy
    Jawad Fares et al, 2021 CrossRef
57. Identification of the Prognostic Signatures of Glioma With Different PTEN Status
    Pei Zhang et al, 2021, Front. Oncol. CrossRef
58. The roles of FOXM1 in pancreatic stem cells and carcinogenesis
    Ming Quan et al, 2013, Mol Cancer CrossRef
59. Tackling of Renal Carcinogenesis in Wistar Rats by Silybum marianum Total Extract, Silymarin, and Silibinin via Modulation of Oxidative Stress, Apoptosis, Nrf2, PPARγ, NF-κB, and PI3K/Akt Signaling Pathways
    Nour Y. S. Yassin et al, 2021, Oxidative Medicine and Cellular Longevity CrossRef
60. PIM1 Inhibition Affects Glioblastoma Stem Cell Behavior and Kills Glioblastoma Stem-like Cells
    Carolin Seifert et al, 2021, IJMS CrossRef
61. USP25 Regulates the Proliferation and Apoptosis of Ovarian Granulosa Cells in Polycystic Ovary Syndrome by Modulating the PI3K/AKT Pathway via Deubiquitinating PTEN
    Yue Gao et al, 2021, Front. Cell Dev. Biol. CrossRef
62. Let-7a suppresses Ewing sarcoma CSCs’ malignant phenotype via forming a positive feedback circuit with STAT3 and lin28
    Jiang Xu et al, 2021, Journal of Bone Oncology CrossRef
63. Ipilimumab, Pembrolizumab, or Nivolumab in Combination with BBI608 in Patients with Advanced Cancers Treated at MD Anderson Cancer Center
    Henry Hiep Vo et al, 2022, Cancers CrossRef
64. PTEN in cancer associated fibroblasts
    Julia E. Lefler et al, 2022 CrossRef
65. A Tumor Suppressor Gene, N-myc Downstream-Regulated Gene 1 (NDRG1), in Gliomas and Glioblastomas
    Yukiko Nakahara et al, 2022, Brain Sciences CrossRef
66. STAT3 in tumor fibroblasts promotes an immunosuppressive microenvironment in pancreatic cancer
    Julia E Lefler et al, 2022, Life Sci. Alliance CrossRef
67. Signaling pathways governing glioma cancer stem cells behavior
    Ava Nasrolahi et al, 2022, Cellular Signalling CrossRef
68. Emerging trends and research foci of epithelial–mesenchymal transition in gliomas: A scientometric analysis and review
    Yang Xing et al, 2022, Front. Oncol. CrossRef
69. Functional and Molecular Characters of Cancer Stem Cells Through Development to Establishment
    Said M. Afify et al, 2022 CrossRef
70. ERBB Signaling Pathway in Cancer Stem Cells
    Ghmkin Hassan et al, 2022 CrossRef
71. Progress in targeting PTEN/PI3K/Akt axis in glioblastoma therapy: Revisiting molecular interactions
    Mehrdad Hashemi et al, 2023, Biomedicine & Pharmacotherapy CrossRef
72. MEK5-ERK5 Axis Promotes Self-renewal and Tumorigenicity of Glioma Stem Cells
    Kazuya Fukasawa et al, 2023 CrossRef
73. USP25 Regulates the Proliferation and Apoptosis of Ovarian Granulosa Cells In Polycystic Ovary Syndrome by Modulating the PI3K/AKT Pathway via Deubiquitinating PTEN
    Yue Gao et al, 2021, SSRN Journal CrossRef
74. Multi-Omics Identification of Genetic Alterations in Head and Neck Squamous Cell Carcinoma and Therapeutic Efficacy of HNC018 as a Novel Multi-Target Agent for c-MET/STAT3/AKT Signaling Axis
    Harshita Nivrutti Khedkar et al, 2023, IJMS CrossRef
75. Ginseng polysaccharide promotes the apoptosis of colon cancer cells via activating the NLRP3 inflammasome
    Xiaoyan Tian et al, 2024, Immunopharmacology and Immunotoxicology CrossRef
76. Interleukin 6 and cancer resistance in glioblastoma multiforme
    Donald Detchou et al, 2024, Neurosurg Rev CrossRef
77. PP2 Suppresses Proliferation and Migration of C6 Glioma and MDA-MB-231 Cells by Targeting both Fibroblast Growth Factor Receptor 1 and Src
    Yanyan Yang et al, 2024, Chemico-Biological Interactions CrossRef