- A new niclosamide derivatives-B17 can inhibit urological cancers growth through apoptosis-related pathway
Chia-Lun Wu et al, 2018, Cancer Med CrossRef - Conjugation of Ginsenoside with Dietary Amino Acids: A Promising Strategy To Suppress Cell Proliferation and Induce Apoptosis in Activated Hepatic Stellate Cells
Lu Ma et al, 2019, J. Agric. Food Chem. CrossRef - Research Advances in the Use of Histone Deacetylase Inhibitors for Epigenetic Targeting of Cancer.
Yu Bai et al, 2019, Curr Top Med Chem CrossRef - Current overview on the clinical update of Bcl-2 anti-apoptotic inhibitors for cancer therapy
Vasanti Suvarna et al, 2019, European Journal of Pharmacology CrossRef - Calreticulin regulated intrinsic apoptosis through mitochondria-dependent and independent pathways mediated by ER stress in arsenite exposed HT-22 cells
Xiaotong Wang et al, 2020, Chemosphere CrossRef - Bcl-2/Bcl-xl inhibitor APG-1252-M1 is a promising therapeutic strategy for gastric carcinoma.
Hanjie Yi et al, 2020, Cancer Med CrossRef - Inhibition of Anti-Apoptotic Bcl-2 Proteins in Preclinical and Clinical Studies: Current Overview in Cancer.
Simona D'Aguanno et al, 2020, Cells CrossRef - Anticancer Agents Based on Vulnerable Components in a Signalling Pathway
Ankur Vaidya et al, 2020, MRMC CrossRef - Rational design, synthesis and biological evaluation of triphenylphosphonium-ginsenoside conjugates as mitochondria-targeting anti-cancer agents
Lu Ma et al, 2020, Bioorganic Chemistry CrossRef - The interplay between apoptosis and cellular senescence: Bcl-2 family proteins as targets for cancer therapy.
Alakananda Basu, 2022, Pharmacol Ther CrossRef - Gemcitabine and APG-1252, a novel small molecule inhibitor of BCL-2/BCL-XL, display a synergistic antitumor effect in nasopharyngeal carcinoma through the JAK-2/STAT3/MCL-1 signaling pathway
Fan Luo et al, 2021, Cell Death Dis CrossRef -
Strategies to Reduce the On‐Target Platelet Toxicity of Bcl‐x
L
Inhibitors: PROTACs, SNIPERs and Prodrug‐Based Approaches
Arvind Negi et al, 2022, ChemBioChem CrossRef - Mcl-1 levels critically impact the sensitivities of human colorectal cancer cells to APG-1252-M1, a novel Bcl-2/Bcl-XL dual inhibitor that induces Bax-dependent apoptosis
Weilong Yao et al, 2022, Neoplasia CrossRef -
Therapeutic potential of the novel Bcl‐2/Bcl‐X
L
dual inhibitor, APG1252, alone or in combination against non‐small cell lung cancer
Luxi Qian et al, 2022, Molecular Carcinogenesis CrossRef - Anti-tumor effect of antibody drug conjugate ASP1235 targeting Fms-like tyrosine kinase 3 with venetoclax plus azacitidine in an acute myeloid leukemia xenograft mouse model
Hirofumi Tsuzuki et al, 2022, Oncotarget CrossRef - Programmed cell death, redox imbalance, and cancer therapeutics.
Xiaofeng Dai et al, 2021, Apoptosis CrossRef - Recent advances in targeting the “undruggable” proteins: from drug discovery to clinical trials
Xin Xie et al, 2023, Sig Transduct Target Ther CrossRef - B‐cell lymphoma‐2 family proteins in the crosshairs: Small molecule inhibitors and activators for cancer therapy
Qineng Gong et al, 2023, Medicinal Research Reviews CrossRef - BCL-2 inhibition in haematological malignancies: Clinical application and complications
Dominic J. Fowler-Shorten et al, 2024, Blood Reviews CrossRef - Brucine Inhibits Proliferation of Pancreatic Ductal Adenocarcinoma
through PI3K/AKT Pathway-induced Mitochondrial Apoptosis
You Wu et al, 2024, CCDT CrossRef - APG-1252 combined with Cabozantinib inhibits hepatocellular carcinoma by suppressing MEK/ERK and CREB/Bcl-xl pathways
Tian Di et al, 2024, International Immunopharmacology CrossRef - The novel BCL-2/BCL-XL inhibitor APG-1252-mediated cleavage of GSDME enhances the antitumor efficacy of HER2-targeted therapy in HER2-positive gastric cancer
Qiu-yun Luo et al, 2024, Acta Pharmacol Sin CrossRef