1. Preventative and Therapeutic Effects of Metformin in Gastric Cancer: A New Contribution of an Old Friend


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  2. An SGLT2 inhibitor modulates SHH expression by activating AMPK to inhibit the migration and induce the apoptosis of cervical carcinoma cells
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  3. Chemopreventive Effect of Metformin on Gastric Cancer Development
    Ka Shing Cheung et al, 2022, Gut and Liver CrossRef
  4. Repurposed Biguanide Drugs in Glioblastoma Exert Antiproliferative Effects via the Inhibition of Intracellular Chloride Channel 1 Activity
    Federica Barbieri et al, 2019, Frontiers in Oncology CrossRef
  5. Metformin exerts anti-tumor effects via Sonic hedgehog signaling pathway by targeting AMPK in HepG2 cells
    Ang Hu et al, 2022, Biochemistry and Cell Biology CrossRef
  6. The Relationship between Diabetes Mellitus and Gastric Cancer and the Potential Benefits of Metformin: An Extensive Review of the Literature
    Chin-Hsiao Tseng, 2021, Biomolecules CrossRef
  7. Sulforaphane inhibits self-renewal of lung cancer stem cells through the modulation of sonic Hedgehog signaling pathway and polyhomeotic homolog 3
    Fanping Wang et al, 2021, AMB Express CrossRef
  8. Repurposed Drugs in Gastric Cancer
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  9. Saikosaponin-d Inhibits the Hepatoma Cells and Enhances Chemosensitivity Through SENP5-Dependent Inhibition of Gli1 SUMOylation Under Hypoxia
    Chun-Yan Zhang et al, 2019, Frontiers in Pharmacology CrossRef
  10. Integrated or Independent Actions of Metformin in Target Tissues Underlying Its Current Use and New Possible Applications in the Endocrine and Metabolic Disorder Area
    Giovanni Tulipano, 2021, International Journal of Molecular Sciences CrossRef
  11. Research Progress on Anti-Tumor Effect of Metformin in Gastric Cancer
    礼琴 贺, 2019, Advances in Clinical Medicine CrossRef
  12. The Neurodevelopmental and Molecular Landscape of Medulloblastoma Subgroups: Current Targets and the Potential for Combined Therapies
    Hasan Slika et al, 2023, Cancers CrossRef
  13. Metformin regulates macrophage polarization via the Shh signaling pathway to improve pulmonary vascular development in bronchopulmonary dysplasia
    Xiaowen Xiang et al, 2022, IUBMB Life CrossRef
  14. Molecular mechanisms underlying the action of carcinogens in gastric cancer with a glimpse into targeted therapy
    Elham Patrad et al, 2022, Cellular Oncology CrossRef
  15. Drug Repurposing in Gastric Cancer: Current Status and Future Perspectives
    Marina Leite et al, 2023, Hereditary Gastric and Breast Cancer Syndrome CrossRef
  16. Formulation and Characterization of Metformin-Loaded Ethosomes for Topical Application to Experimentally Induced Skin Cancer in Mice
    Ibrahim A. Mousa et al, 2022, Pharmaceuticals CrossRef
  17. Cepharanthine hydrochloride inhibits the Wnt/β‑catenin/Hedgehog signaling axis in liver cancer
    Gui-Feng Su et al, 2022, Oncology Reports CrossRef
  18. AMPK: An odyssey of a metabolic regulator, a tumor suppressor, and now a contextual oncogene
    Vasudevarao Penugurti et al, 2022, Biochimica et Biophysica Acta (BBA) - Reviews on Cancer CrossRef
  19. Harnessing drug/radiation interaction through daily routine practice: Leverage medical and methodological point of view (MORSE 02-17 study)
    A. Vallard et al, 2018, Radiotherapy and Oncology CrossRef
  20. The therapeutic potential of metformin in gastric cancer
    Sarah Courtois et al, 2019, Gastric Cancer CrossRef
  21. Cancer as a biophysical disease: Targeting the mechanical-adaptability program
    Ly T.S. Nguyen et al, 2022, Biophysical Journal CrossRef
  22. Efficacy of Metformin and Chemotherapeutic Agents on the Inhibition of Colony Formation and Shh/Gli1 Pathway: Metformin/Docetaxel Versus Metformin/5-Fluorouracil
    Maryam Fatehi-Agdam et al, 2021, Drug Research CrossRef
  23. Cross-talk between AMP-activated protein kinase and the sonic hedgehog pathway in the high-fat diet triggered colorectal cancer
    T.B. Beena et al, 2023, Archives of Biochemistry and Biophysics CrossRef
  24. Metformin is associated with decreased risk of basal cell carcinoma: A whole-population case-control study from Iceland
    Jonas A. Adalsteinsson et al, 2021, Journal of the American Academy of Dermatology CrossRef