1. Psoralidin inhibits proliferation and enhances apoptosis of human esophageal carcinoma cells via NF-κB and PI3K/Akt signaling pathways
    Zhiliang Jin et al, 2016 CrossRef
  2. MicroRNA-136 functions as a tumor suppressor in osteosarcoma via regulating metadherin
    Tao Guo et al, 2018, CBM CrossRef
  3. AEG-1 Contributes to Metastasis in Hypoxia-Related Ovarian Cancer by Modulating the HIF-1alpha/NF-kappaB/VEGF Pathway
    Xiaoyu Yu et al, 2018, BioMed Research International CrossRef
  4. Epigenetic Regulators of PD-L1 Expression in Human Cancers
    Sachin Kumar et al, 2018, Translational Research CrossRef
  5. Efficient and tumor-specific knockdown of MTDH gene attenuates paclitaxel resistance of breast cancer cells both in vivo and in vitro
    Liu Yang et al, 2018, Breast Cancer Res CrossRef
  6. Effects of lentivirus-mediated astrocyte elevated gene-1 overexpression on proliferation and apoptosis of human retinoblastoma cells
    Haixia Bai et al, 2019, Acta Ophthalmol CrossRef
  7. Activation of EMT in colorectal cancer by MTDH/NF-κB p65 pathway
    Nahla E. El-Ashmawy et al, 2019, Mol Cell Biochem CrossRef
  8. Effect of modification of MTDH gene expression on colorectal cancer aggressiveness
    Nahla E. El-Ashmawy et al, 2019, Gene CrossRef
  9. MiR-145 acts as a metastasis suppressor by targeting metadherin in lung cancer.
    Mingzhi Wang et al, 2015, Med Oncol CrossRef
  10. MicroRNA-542-3p suppresses cell growth of gastric cancer cells via targeting oncogene astrocyte-elevated gene-1
    Xinsheng Shen et al, 2015, Med Oncol CrossRef
  11. HTRA1(High Temperature Requirement A Serine Peptidase 1) Gene Is Transcriptionally Regulated by Insertion/Deletion Nucleotides Located at the 3′ End of theARMS2(Age-related Maculopathy Susceptibility 2) Gene in Patients with Age-related Macular Degeneration
    Daisuke Iejima et al, 2015, J. Biol. Chem. CrossRef
  12. MTDH/AEG-1-based DNA vaccine suppresses metastasis and enhances chemosensitivity to paclitaxel in pelvic lymph node metastasis.
    Chun Zhang et al, 2015, Biomed Pharmacother CrossRef
  13. MiR-302c-3p suppresses invasion and proliferation of glioma cells via down-regulating metadherin (MTDH) expression
    Yonghong Wang et al, 2015, Cancer Biology & Therapy CrossRef
  14. High-Content Functional Screening ofAEG-1andAKR1C2for the Promotion of Metastasis in Liver Cancer
    Cong Li et al, 2016, J Biomol Screen CrossRef
  15. How does the oncogene astrocyte elevated gene-1 (AEG-1) augment glioma progression?
    Luni Emdad et al, 2015, Future Neurology CrossRef
  16. Overexpression of microRNA-30a-5p inhibits liver cancer cell proliferation and induces apoptosis by targeting MTDH/PTEN/AKT pathway.
    Wen-Fang Li et al, 2016, Tumour Biol CrossRef
  17. Metadherin Expression is Associated with Extrathyroidal Extension in Papillary Thyroid Cancer Patients
    Robert F. Moore et al, 2016, Ann Surg Oncol CrossRef
  18. MicroRNA-124 inhibits proliferation, invasion, migration and epithelial-mesenchymal transition of cervical carcinoma cells by targeting astrocyte-elevated gene-1
    Xia Zhang et al, 2016 CrossRef
  19. AEG-1 promotes mesenchymal transition through the activation of Rho GTPases in human glioblastoma cells
    Sang-Yoon Park et al, 2016 CrossRef
  20. MicroRNA-1297 inhibits prostate cancer cell proliferation and invasion by targeting the AEG-1/Wnt signaling pathway
    Xuan Liang et al, 2016, Biochemical and Biophysical Research Communications CrossRef
  21. Knockdown of astrocyte elevated gene-1 inhibited cell growth and induced apoptosis and suppressed invasion in ovarian cancer cells
    Jiewen Wang et al, 2017, Gene CrossRef
  22. Silencing of astrocyte elevated gene-1 inhibits proliferation and migration of melanoma cells and induces apoptosis.
    Yue Zhang et al, 0 CrossRef
  23. Overexpression of microRNA-448 inhibits osteosarcoma cell proliferation and invasion through targeting of astrocyte elevated gene-1
    Weibo Jiang et al, 2017 CrossRef
  24. Reduced microRNA 375 in colorectal cancer upregulates metadherin-mediated signaling
    Seol-Hee Han et al, 2019, WJG CrossRef

  25. Long Noncoding RNA DLGAP1-AS1 Promotes the Aggressive Behavior of Gastric Cancer by Acting as a ceRNA for microRNA-628-5p and Raising Astrocyte Elevated Gene 1 Expression


    Jiying Deng et al, 2020, CMAR CrossRef
  26. miR-217 inhibits laryngeal cancer metastasis by repressing AEG-1 and PD-L1 expression
    Susheng Miao et al, 2017, Oncotarget CrossRef
  27. Astrocyte-elevated gene-1 confers resistance to pemetrexed in non-small cell lung cancer by upregulating thymidylate synthase expression
    Chung-Yu Chen et al, 2017, Oncotarget CrossRef
  28. Dual-strand tumor-suppressor microRNA-145 (miR-145-5p and miR-145-3p) coordinately targeted MTDH in lung squamous cell carcinoma
    Hiroko Mataki et al, 2016, Oncotarget CrossRef
  29. Silencing the expression of MTDH increases the radiation sensitivity of SKOV3 ovarian cancer cells and reduces their proliferation and metastasis
    Jun Chen et al, 2018, Int J Oncol CrossRef
  30. MicroRNA‑675 inhibits cell proliferation and invasion in melanoma by directly targeting metadherin
    Ke Liu et al, 2017, Mol Med Report CrossRef
  31. MicroRNA-499 Suppresses the Growth of Hepatocellular Carcinoma by Downregulating Astrocyte Elevated Gene-1
    Jing Wang et al, 2020, Technol Cancer Res Treat CrossRef
  32. Long non-coding RNA PRNCR1 modulates non-small cell lung cancer cell proliferation, apoptosis, migration, invasion, and EMT through PRNCR1/miR-126-5p/MTDH axis.
    Ran Guo et al, 2020, Biosci Rep CrossRef
  33. Transposon mutagenesis identifies cooperating genetic drivers during keratinocyte transformation and cutaneous squamous cell carcinoma progression
    Aziz Aiderus et al, 2021, PLoS Genet CrossRef
  34. AEG-1 silencing attenuates M2-polarization of glioma-associated microglia/macrophages and sensitizes glioma cells to temozolomide
    Jing Li et al, 2021, Sci Rep CrossRef
  35. AEG-1 Promotes Metastasis Through Downstream AKR1C2 and NF1 in Liver Cancer
    Cong Li et al, 2015, oncol res CrossRef
  36. MicroRNA-342-3p Inhibits the Proliferation, Migration, and Invasion of Osteosarcoma Cells by Targeting Astrocyte-Elevated Gene-1 (AEG-1).
    Shaokun Zhang et al, 0 CrossRef
  37. Metadherin (AEG-1/MTDH/LYRIC) expression: Significance in malignancy and crucial role in colorectal cancer
    Muhammad T. Abdel Ghafar et al, 2022 CrossRef
  38. Role of serum Metadherin mRNA expression in the diagnosis and prediction of survival in patients with colorectal cancer.
    Muhammad Tarek Abdel Ghafar et al, 2020, Mol Biol Rep CrossRef
  39. Metabolomics and biochemical insights on the regulation of aging-related diabetes by a low-molecular-weight polysaccharide from green microalga Chlorella pyrenoidosa
    Yinghui Qiu et al, 2022, Food Chemistry: X CrossRef
  40. Advances in the Biological Functions and Mechanisms of miRNAs in the Development of Osteosarcoma
    Zihe Dong et al, 2022, Technol Cancer Res Treat CrossRef
  41. Molecular biology of microRNA-342 during tumor progression and invasion
    Negin Taghehchian et al, 2023, Pathology - Research and Practice CrossRef
  42. Profiling Kinase Activities for Precision Oncology in Diffuse Gastric Cancer
    Smrita Singh et al, 2024, OMICS: A Journal of Integrative Biology CrossRef