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  2. Thymoquinone Augments Cisplatin-Induced Apoptosis on Esophageal Carcinoma Through Mitigating the Activation of JAK2/STAT3 Pathway
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  3. Therapeutic Potential of Thymoquinone in Glioblastoma Treatment: Targeting Major Gliomagenesis Signaling Pathways
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  4. Improvement of antihyperglycemic activity of nano-thymoquinone in rat model of type-2 diabetes
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  5. Modulation of diverse oncogenic transcription factors by thymoquinone, an essential oil compound isolated from the seeds of Nigella sativa Linn.
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  6. Anticancer Action of Thymoquinone
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  7. Loading of doxorubicin and thymoquinone with F2 gel nanofibers improves the antitumor activity and ameliorates doxorubicin-associated nephrotoxicity
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  8. Thymoquinone inhibits cell proliferation, migration, and invasion by regulating the elongation factor 2 kinase (eEF-2K) signaling axis in triple-negative breast cancer
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  10. Thymoquinone synergizes gemcitabine anti-breast cancer activity via modulating its apoptotic and autophagic activities
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  11. Thymoquinone attenuates phosphorylation of AKT to inhibit kidney cancer cell proliferation
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  13. Stress response due to sodium azide treatment inside Nigella sativa L. plant and its effect on antioxidative property
    Mohammed Shariq Iqbal et al, 2019, Biocatalysis and Agricultural Biotechnology CrossRef
  14. Thymoquinone Enhances the Effect of Gamma Knife in B16-F10 Melanoma Through Inhibition of Phosphorylated STAT3
    Mustafa Aziz Hatiboglu et al, 2019, World Neurosurgery CrossRef
  15. Thymoquinone loaded mesoporous silica nanoparticles retard cell invasion and enhance in vitro cytotoxicity due to ROS mediated apoptosis in HeLa and MCF-7 cell lines
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  17. Fabrication of stimuli gated nanoformulation for site-specific delivery of TQ for colon cancer treatment – Insight into thymoquinone’s improved physicochemical properties
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  18. Thymoquinone and pentoxifylline enhance the chemotherapeutic effect of cisplatin by targeting Notch signaling pathway in mice
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  19. Thymoquinone Enhances Paclitaxel Anti-Breast Cancer Activity via Inhibiting Tumor-Associated Stem Cells Despite Apparent Mathematical Antagonism
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  20. Synthesis and characterization of folic acid-chitosan nanoparticles loaded with thymoquinone to target ovarian cancer cells
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  23. Thymoquinone reduces spinal cord injury by inhibiting inflammatory response, oxidative stress and apoptosis via PPAR-γ and PI3K/Akt pathways.
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  24. Pharmacologically targetable vulnerability in prostate cancer carrying RB1-SUCLA2 deletion
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    Rohini Gomathinayagam et al, 2020, J Cancer Prev CrossRef

  26. Formulation, Cellular Uptake and Cytotoxicity of Thymoquinone-Loaded PLGA Nanoparticles in Malignant Melanoma Cancer Cells


    Wisam Nabeel Ibrahim et al, 2020, IJN CrossRef
  27. Health-Promoting Activities of Nigella sativa Fixed Oil
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  28. Anticancer Activity of Thymoquinone Cubic Phase Nanoparticles Against Human Breast Cancer: Formulation, Cytotoxicity and Subcellular Localization


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  29. Thymoquinone, an Active Compound of Nigella sativa: Role in Prevention and Treatment of Cancer
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  30. Thymoquinone chemosensitizes human colorectal cancer cells to imatinib via uptake/efflux genes modulation.
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  32. Recent Findings on Thymoquinone and Its Applications as a Nanocarrier for the Treatment of Cancer and Rheumatoid Arthritis
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  33. Therapeutic perspectives of the black cumin component thymoquinone: A review
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  34. Thymoquinone and its nanoformulation attenuate colorectal and breast cancers and alleviate doxorubicin-induced cardiotoxicity
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  36. Induction of Autophagic Cell Death by Thymoquinone in Docetaxel Resistant Prostate Cancer Cells
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  37. Triangulating the pharmacological properties of thymoquinone in regulating reactive oxygen species, inflammation, and cancer: Therapeutic applications and mechanistic pathways
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  38. Thymoquinone nanoparticles protect against cisplatin-induced nephrotoxicity in Ehrlich carcinoma model without compromising cisplatin anti-cancer efficacy
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  39. Combinatorial Effect of Thymoquinone with Chemo Agents for Tumor Therapy
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  40. Plants in Anticancer Drug Discovery: From Molecular Mechanism to Chemoprevention
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  42. Thymoquinone Radiosensitizes Human Colorectal Cancer Cells in 2D and 3D Culture Models
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  43. Metformin and Thymoquinone Synergistically Inhibit Proliferation of Imatinib-Resistant Human Leukemic Cells
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  45. Effect of Thymoquinone and Transforming Growth Factor-β1 on the Cell Viability of Nasal Polyp-Derived Fibroblast
    Ferryan Sofyan et al, 2022, Open Access Maced J Med Sci CrossRef
  46. Targeting HIF-1α by Natural and Synthetic Compounds: A Promising Approach for Anti-Cancer Therapeutics Development
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  47. Thymoquinone: A Review on its Pharmacological Importance, and its Association with Oxidative Stress, COVID-19, and Radiotherapy
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  48. Ethnomedicinal uses of Indian spices used for cancer treatment: A treatise on structure-activity relationship and signaling pathways
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  49. Response of Skin-Derived and Metastatic Human Malignant Melanoma Cell Lines to Thymoquinone and Thymoquinone-Loaded Liposomes
    Patrycja Kłos et al, 2022, Pharmaceutics CrossRef
  50. Anticancer Potential of Thymoquinone: A Novel Bioactive Natural Compound from Nigella sativa L.
    Prince Ahad Mir et al, 2022, ACAMC CrossRef
  51. Nigella sativa callus treated with sodium azide exhibit augmented antioxidant activity and DNA damage inhibition
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  53. Natural Compounds Targeting the Autophagy Pathway in the Treatment of Colorectal Cancer
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  54. Characterization of Thymoquinone-Sulfobutylether-β-Cyclodextrin Inclusion Complex for Anticancer Applications
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  55. Potential anticancer properties and mechanisms of thymoquinone in colorectal cancer
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  56. Thymoquinone: A Promising Therapeutic Agent for the Treatment of Colorectal Cancer
    Natalia Kurowska et al, 2023, CIMB CrossRef
  57. A Study on Thymoquinone: Antioxidant Capacity and Anticancer Activities in LoVo Colorectal Cancer Cells.
    Kubra Bozali et al, 2024, Chem Biodivers CrossRef
  58. Investigating anti-cancer activity of dual-loaded liposomes with thymoquinone and vitamin C
    Ahmed Munef et al, 2024, Therapeutic Delivery CrossRef
  59. Tumoricidal properties of thymoquinone on human colorectal adenocarcinoma cells via the modulation of autophagy
    Mohammad Saleh Moulana et al, 2024, BMC Complement Med Ther CrossRef
  60. Effect of Black Cumin (Nigella sativa) on Prostate Health: Narrative Review
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  61. Essential Oils Pharmacological Activity: Chemical Markers, Biogenesis, Plant Sources, and Commercial Products
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  62. Innovative Strategies to Combat 5-Fluorouracil Resistance in Colorectal Cancer: The Role of Phytochemicals and Extracellular Vesicles
    Muttiah Barathan et al, 2024, IJMS CrossRef
  63. Apoptotic and Non-Apoptotic Modalities of Thymoquinone-Induced Lymphoma Cell Death: Highlight of the Role of Cytosolic Calcium and Necroptosis
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  64. Exploring the Therapeutic Potential of 5-Fluorouracil-Loaded Calcium Carbonate Nanoparticles Combined with Natural Compound Thymoquinone for Colon Cancer Treatment
    Xi Deng et al, 2024, Pharmaceutics CrossRef
  65. Nanoalchemy: Unveiling the Power of Carbon Nanostructures and Carbon–Metal Nanocomposites in Synthesis and Photocatalytic Activity
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  66. Comprehensive Insights Into the Combinatorial Uses of Selected Phytochemicals in Colorectal Cancer Prevention and Treatment: Isothiocyanates, Quinones, Carotenoids, and Alkaloids
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  67. Unleashing of cytotoxic effects of thymoquinone-bovine serum albumin nanoparticles on A549 lung cancer cells
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  68. Molecular Mechanisms and Signaling Pathways Underlying the Therapeutic Potential of Thymoquinone Against Colorectal Cancer
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