1. The role of NEDD4 related HECT-type E3 ubiquitin ligases in defective autophagy in cancer cells: molecular mechanisms and therapeutic perspectives
    Rui Zhang et al, 2023, Molecular Medicine CrossRef
  2. Loss of NEDD4 causes complete XY gonadal sex reversal in mice
    Simon P. Windley et al, 2022, Cell Death & Disease CrossRef
  3. CFDP1 promotes hepatocellular carcinoma progression through activating NEDD4/PTEN/PI3K/AKT signaling pathway
    Yan Zhou et al, 2023, Cancer Medicine CrossRef
  4. LINC01419-mediated epigenetic silencing of ZIC1 promotes metastasis in hepatocellular carcinoma through the PI3K/Akt signaling pathway
    Yifu Hou et al, 2021, Laboratory Investigation CrossRef
  5. Targeting the E3 ligase NEDD4 as a novel therapeutic strategy for IGF1 signal pathway-driven gastric cancer
    Ke Wang et al, 2023, Oncogene CrossRef
  6. miR-382-5p promotes cell invasion in hepatocellular carcinoma by targeting PTEN to activate PI3K/Akt signaling pathway
    Bo Lv et al, 2022, World Journal of Surgical Oncology CrossRef
  7. The many substrates and functions of NEDD4-1
    Xi Huang et al, 2019, Cell Death & Disease CrossRef
  8. BRCA1 mutations in high-grade serous ovarian cancer are associated with proteomic changes in DNA repair, splicing, transcription regulation and signaling
    Melissa Bradbury et al, 2022, Scientific Reports CrossRef
  9. NEDD4 regulates ubiquitination and stability of the cell adhesion molecule IGPR-1 via lysosomal pathway
    Linzi Sun et al, 2021, Journal of Biomedical Science CrossRef
  10. The E3 ubiquitin ligase NEDD4 mediates cell migration signaling of EGFR in lung cancer cells
    Genbao Shao et al, 2018, Molecular Cancer CrossRef
  11. Pharmacological Modulation of Ubiquitin-Proteasome Pathways in Oncogenic Signaling
    Anmol Sharma et al, 2021, International Journal of Molecular Sciences CrossRef
  12. NEDD4 E3 ubiquitin ligases: Promising biomarkers and therapeutic targets for cancer
    Xianyan Tian et al, 2023, Biochemical Pharmacology CrossRef
  13. Unraveling the Potential Role of NEDD4-like E3 Ligases in Cancer
    Sujitha Jayaprakash et al, 2022, International Journal of Molecular Sciences CrossRef
  14. Folic-Acid-Adorned PEGylated Graphene Oxide Interferes with the Cell Migration of Triple Negative Breast Cancer Cell Line, MDAMB-231 by Targeting miR-21/PTEN Axis through NFκB
    Arijita Basu et al, 2019, ACS Biomaterials Science & Engineering CrossRef
  15. The NEDD4‐1 E3 ubiquitin ligase: A potential molecular target for bortezomib sensitivity in multiple myeloma
    Xi Huang et al, 2020, International Journal of Cancer CrossRef
  16. Integrated bioinformatics analysis of the NEDD4 family reveals a prognostic value of NEDD4L in clear-cell renal cell cancer
    Hui Zhao et al, 2021, PeerJ CrossRef
  17. Clinicopathological and prognostic correlations of HER3 expression and its degradation regulators, NEDD4–1 and NRDP1, in primary breast cancer
    Satu Luhtala et al, 2018, BMC Cancer CrossRef
  18. The NEDD4 ubiquitin E3 ligase: a snapshot view of its functional activity and regulation
    Daria Sicari et al, 2022, Biochemical Society Transactions CrossRef
  19. miR‑494‑3p promotes the progression of endometrial cancer by regulating the PTEN/PI3K/AKT pathway
    Lichao Zhu et al, 2018, Molecular Medicine Reports CrossRef
  20. Insufficient ablation induces E3-ligase Nedd4 to promote hepatocellular carcinoma progression by tuning TGF-β signaling
    Kai Li et al, 2022, Oncogene CrossRef
  21. Ubiquitination/de-ubiquitination: A promising therapeutic target for PTEN reactivation in cancer
    Ke Wang et al, 2022, Biochimica et Biophysica Acta (BBA) - Reviews on Cancer CrossRef
  22. MicroRNA‐155‐5p in serum derived‐exosomes promotes ischaemia–reperfusion injury by reducing CypD ubiquitination by NEDD4
    Chenkai Hu et al, 2023, ESC Heart Failure CrossRef
  23. NEDD4 E3 ligase: Functions and mechanism in human cancer
    Zhi-wei Wang et al, 2020, Seminars in Cancer Biology CrossRef
  24. Ubiquitin–proteasome system (UPS) as a target for anticancer treatment
    Jinyoung Park et al, 2020, Archives of Pharmacal Research CrossRef
  25. The role of ubiquitination and deubiquitination in PI3K/AKT/mTOR pathway: A potential target for cancer therapy
    Jiabei Jin et al, 2023, Gene CrossRef
  26. E3 ubiquitin ligase neural precursor cell‐expressed developmentally downregulated gene 4 motivates FOXA1 ubiquitination and restrains proliferation of diffuse large B‐cell lymphoma cells via the Wnt/β‐Catenin pathway
    Li Yang et al, 2023, Cell Biology International CrossRef