Cancer stem cells: involvement in pancreatic cancer pathogenesis and perspectives on cancer therapeutics. Cristiana Pistol Tanase et al, 2014, World J. Gastroenterol. CrossRef
Novel therapeutic targets for pancreatic cancer Shing-Chun Tang, 2014, WJG CrossRef
Epithelial-mesenchymal transition - activating transcription factors - multifunctional regulators in cancer Minal Garg, 2013, WJSC CrossRef
Activation of sonic hedgehog signaling enhances cell migration and invasion by induction of matrix metalloproteinase-2 and -9 via the phosphoinositide-3 kinase/AKT signaling pathway in glioblastoma LIANG CHANG et al, 2015 CrossRef
Identification of dysregulated pathways associated with pancreatic cancer by survival analysis QIONG-YING YUAN et al, 2015 CrossRef
A sesquiterpene lactone from Siegesbeckia glabrescens suppresses Hedgehog/Gli-mediated transcription in pancreatic cancer cells Hwa Jin Lee et al, 2016 CrossRef
TNF-α enhances the effect of TGF-β on Gli2 expression in the KG-1 leukemic cell line ZHE LI et al, 2014 CrossRef
Molecular Drivers of Pancreatic Cancer Pathogenesis: Looking Inward to Move Forward Mohammad Aslam Khan et al, 2017, IJMS CrossRef
Endometrial stem cell-derived granulocyte-colony stimulating factor attenuates endometrial fibrosis via sonic hedgehog transcriptional activator Gli2† Xiaona Lin et al, 2018 CrossRef
Hedgehog signalling in the tumourigenesis and metastasis of osteosarcoma, and its potential value in the clinical therapy of osteosarcoma Zhihong Yao et al, 2018, Cell Death Dis CrossRef
The influence of aberrant expression of GLI1/p-S6K on colorectal cancer Xuchao Wang et al, 2018, Biochemical and Biophysical Research Communications CrossRef
Epigenetic silencing of sonic hedgehog elicits antitumor immune response and suppresses tumor growth by inhibiting the hedgehog signaling pathway in metastatic spine tumors in Sprague-Dawley rats Guang Shi et al, 2018, J Cell Biochem CrossRef
Inhibition of sonic hedgehog and PI3K/Akt/mTOR pathways cooperate in suppressing survival, self-renewal and tumorigenic potential of glioblastoma-initiating cells Rajesh Nanta et al, 2018, Mol Cell Biochem CrossRef
Targeting Hedgehog signaling pathway: paving the road for cancer therapy Ioana Berindan-Neagoe et al, 2019, Pharmacological Research CrossRef
The Molecular Connections between Lung and Pancreatic Cancer Metastases: are we not seeing the Forest for the Trees? Angelo Wilson, 2017, JCPCR CrossRef
Ellagic acid inhibits human pancreatic cancer growth in Balb c nude mice Min Zhao et al, 2013, Cancer Letters CrossRef
Crosstalk between hedgehog and other signaling pathways as a basis for combination therapies in cancer Jillian Brechbiel et al, 2014, Cancer Treatment Reviews CrossRef
Embelin Suppresses Growth of Human Pancreatic Cancer Xenografts, and Pancreatic Cancer Cells Isolated from KrasG12D Mice by Inhibiting Akt and Sonic Hedgehog Pathways Minzhao Huang et al, 2014, PLoS ONE CrossRef
Rottlerin suppresses growth of human pancreatic tumors in nude mice, and pancreatic cancer cells isolated from KrasG12D mice Minzhao Huang et al, 2014, Cancer Letters CrossRef
Anti-fibrotic and Anti-tumorigenic Effects of Rhein, a Natural Anthraquinone Derivative, in Mammalian Stellate and Carcinoma Cells Siu Wai Tsang et al, 2015, Phytother. Res. CrossRef
Potential molecular, cellular and microenvironmental mechanism of sorafenib resistance in hepatocellular carcinoma. Jiang Chen et al, 2015, Cancer Lett. CrossRef
Pharmacological GLI2 inhibition prevents myofibroblast cell-cycle progression and reduces kidney fibrosis Rafael Kramann et al, 2015, J. Clin. Invest. CrossRef
The sonic hedgehog signaling pathway contributes to the development of salivary gland neoplasms regardless of perineural infiltration Manuela Torres Andion Vidal et al, 2016, Tumor Biol. CrossRef
Hedgehog signaling: modulation of cancer properies and tumor mircroenvironment Ann Hanna et al, 2016, Mol Cancer CrossRef
Design, Synthesis and Biological Evaluation of novel Hedgehog Inhibitors for treating Pancreatic Cancer Vinod Kumar et al, 2017, Sci Rep CrossRef
Matrix metalloproteinase-9 regulates the blood brain barrier via the hedgehog pathway in a rat model of traumatic brain injury. Mu-Yao Wu et al, 2020, Brain Res CrossRef
Down-regulation of ATAD2 restrains cancer stem cell properties in esophageal squamous cell carcinoma via blockade of the Hedgehog signaling pathway Nuo Li et al, 2019, American Journal of Physiology-Cell Physiology CrossRef
Sonic Hedgehog gene as a potential target for the early prophylactic detection of cancer C. RupikaSunidhi et al, 2019, Medical Hypotheses CrossRef
Receptor activator for nuclear factor-κB ligand signaling promotes progesterone-mediated estrogen-induced mammary carcinogenesis. Ramadevi Subramani et al, 2015, Cancer Sci. CrossRef
Dauricine suppresses the growth of pancreatic cancer in�vivo by modulating the Hedgehog signaling pathway Ying‑Bo Zhang et al, 2019, Oncol Lett CrossRef
Expression of Smo in pancreatic cancer CD44+CD24+cells and construction of a lentiviral expression vector to silence Smo Peng Cong et al, 2018, Oncol Lett CrossRef
Crosstalk of Hedgehog and mTORC1 Pathways Lasse Jonsgaard Larsen et al, 2020, Cells CrossRef
Forkhead Box S1 Inhibits the Progression of Hepatocellular Carcinoma
Inhibition of TGF-β1 on Gli2 expression was promoted by TNF-α in primary leukemia cells Zhe Li et al, 2021, Journal of Receptors and Signal Transduction CrossRef
Therapeutic Status and Available Strategies in Pancreatic Ductal Adenocarcinoma Gitika Thakur et al, 2021, Biomedicines CrossRef
Expression pattern and prognostic value of circadian clock genes in pancreatic adenocarcinoma Le-Le Zhang et al, 2021, Chronobiology International CrossRef
The roles of FOXM1 in pancreatic stem cells and carcinogenesis Ming Quan et al, 2013, Mol Cancer CrossRef
Proteogenomic analysis of pancreatic cancer subtypes Doris Kafita et al, 2021, PLoS ONE CrossRef
Arsenic trioxide inhibits the Hedgehog pathway which is aberrantly activated in acute promyelocytic leukemia. Dongguang Yang et al, 0 CrossRef
Evaluation of the toxicity of Caralluma europaea (C.E) extracts and their effects on apoptosis and chemoresistance in pancreatic cancer cells Fatima Ez-Zahra Amrati et al, 2022, Journal of Biomolecular Structure and Dynamics CrossRef
CBC-1 as a Cynanbungeigenin C derivative inhibits the growth of colorectal cancer through targeting Hedgehog pathway component GLI 1 Jinwen Chen et al, 2024, Steroids CrossRef
New Smoothened ligands based on the purine scaffold as potential agents for treating pancreatic cancer Christian Espinosa-Bustos et al, 2024, Bioorganic Chemistry CrossRef
Mapping the intricacies of GLI1 in hedgehog signaling: A combined bioinformatics and clinical analysis in Head & Neck cancer in Western India Hitarth V. Patel et al, 2024, Current Problems in Cancer CrossRef
miR-630 as a therapeutic target in pancreatic cancer stem cells: modulation of the PRKCI-Hedgehog signaling axis Jun Zou et al, 2024, Biol Direct CrossRef
Synthesis, antitumoral activity, and in silico studies on Smoothened receptor of new 2,6,9-trisubstituted purine derivatives Christian Espinosa-Bustos et al, 2025, Journal of Molecular Structure CrossRef