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2. Mechanistic Study of Human Glucose Transport Mediated by GLUT1
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3. Perspective on the dynamics of cancer
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4. A mitochondria targeting Mn nanoassembly of BODIPY for LDH-A, mitochondria modulated therapy and bimodal imaging of cancer
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5. Assessment of the low inhibitory specificity of oxamate, aminooxyacetate and dichloroacetate on cancer energy metabolism
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6. An aptamer-Fe 3+ modified nanoparticle for lactate oxidation and tumor photodynamic therapy
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7. Cancer cell metabolic plasticity allows resistance to NAMPT inhibition but invariably induces dependence on LDHA
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8. Oxamate, but Not Selective Targeting of LDH-A, Inhibits Medulloblastoma Cell Glycolysis, Growth and Motility
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9. Metabolic reprogramming enables hepatocarcinoma cells to efficiently adapt and survive to a nutrient-restricted microenvironment
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10. Warburg effect, lactate dehydrogenase, and radio/chemo-therapy efficacy
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11. Prognostic significance of pretreated serum lactate dehydrogenase level in nasopharyngeal carcinoma among Chinese population
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12. Prognostic Value of Lactate Dehydrogenase in Patients with Hepatocellular Carcinoma: A Meta-Analysis
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13. Novel Peptide Inhibitors for Lactate Dehydrogenase A (LDHA): A Survey to Inhibit LDHA Activity via Disruption of Protein-Protein Interaction
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14. ROS homeostasis and metabolism: a dangerous liason in cancer cells
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15. Unappreciated Role of LDHA and LDHB to Control Apoptosis and Autophagy in Tumor Cells.
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16. Pluronic block copolymers enhance the anti-myeloma activity of proteasome inhibitors
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17. Targeting Mitochondria: A Powerhouse Approach to Cancer Treatment
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18. Inhibition of EGFR-induced glucose metabolism sensitizes chondrosarcoma cells to cisplatin
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19. MiR-451 increases radiosensitivity of nasopharyngeal carcinoma cells by targeting ras-related protein 14 (RAB14)
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20. Targeting Cellular Metabolism Modulates Head and Neck Oncogenesis
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21. Fenofibrate Increases Radiosensitivity in Head and Neck Squamous Cell Carcinoma via Inducing G2/M Arrest and Apoptosis
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22. Enzymes of the central carbon metabolism: Are they linkers between transcription, DNA replication, and carcinogenesis?
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23. Lactate dehydrogenase 5: An old friend and a new hope in the war on cancer
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24. Prognostic role of lactate dehydrogenase in solid tumors: A systematic review and meta-analysis of 76 studies
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25. Identification of N-acylhydrazone derivatives as novel lactate dehydrogenase A inhibitors
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26. The Regulation and Function of Lactate Dehydrogenase A: Therapeutic Potential in Brain Tumor
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27. Fragment‐Based Discovery of Inhibitors of Lactate Dehydrogenase A
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28. Oxamate Improves Glycemic Control and Insulin Sensitivity via Inhibition of Tissue Lactate Production in db/db Mice
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29. Tributyltin induces G2/M cell cycle arrest via NAD⁺-dependent isocitrate dehydrogenase in human embryonic carcinoma cells
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30. N -Acetyl- l -cysteine enhances ex-vivo amplification of deciduous teeth dental pulp stem cells
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31. 125I suppressed the Warburg effect viaregulating miR-338/PFKL axis in hepatocellular carcinoma
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32. Transformation by different oncogenes relies on specific metabolic adaptations.
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33. Oroxylin a could be a Promising Radiosensitizer for Esophageal Squamous Cell Carcinoma by Inducing G2/M Arrest and Activating Apoptosis
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34. Reexamining cancer metabolism: lactate production for carcinogenesis could be the purpose and explanation of the Warburg Effect
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35. Pretreatment elevated serum lactate dehydrogenase as a significant prognostic factor in malignant mesothelioma
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36. LDHA Promotes Oral Squamous Cell Carcinoma Progression Through Facilitating Glycolysis and Epithelial-Mesenchymal Transition.
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37. Modulation of dysregulated cancer metabolism by plant secondary metabolites: A mechanistic review
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38. Antagonistic effects of selenium on cadmium-induced apoptosis by restoring the mitochondrial dynamic equilibrium and energy metabolism in chicken spleens
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39. The preclinical study of predicting radiosensitivity in human nasopharyngeal carcinoma xenografts by 18F-ML-10 animal- PET/CT imaging
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40. microRNA-33a-5p increases radiosensitivity by inhibiting glycolysis in melanoma
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41. Identification of genes and pathways in nasopharyngeal carcinoma by bioinformatics analysis.
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42. Post-treatment serum lactic dehydrogenase as a predictive indicator for distant metastasis and survival of patients with nasopharyngeal carcinoma
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43. MiR-34b-3 and miR-449a inhibit malignant progression of nasopharyngeal carcinoma by targeting lactate dehydrogenase A
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44. Different effects of LDH-A inhibition by oxamate in non-small cell lung cancer cells
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45. The synergistic antitumour effect of multi-components from Pulsatilla chinensis saponins in NCI-H460 lung cancer cell line through induction of apoptosis
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46. Circle RNA circABCB10 Modulates PFN2 to Promote Breast Cancer Progression, as Well as Aggravate Radioresistance Through Facilitating Glycolytic Metabolism Via miR-223-3p
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47. Tumor necrosis factor-α triggers opposing signals in head and neck squamous cell carcinoma and induces apoptosis via mitochondrial- and non-mitochondrial-dependent pathways
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48. Lactate production by Staphylococcus aureus biofilm inhibits HDAC11 to reprogramme the host immune response during persistent infection
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49. Bioinformatics analysis identifies hub genes and pathways in nasopharyngeal carcinoma
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50. Flavonoids against the Warburg phenotype—concepts of predictive, preventive and personalised medicine to cut the Gordian knot of cancer cell metabolism
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51. Lanthanide(III) complexes with N-(2,6-dimethylphenyl)oxamate and 1,10-phenanthroline: Synthesis, characterisation and cytotoxicity against MCF-7, HEC-1A and THP-1 cell lines
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52. Clinical Characteristics and Prognostic Factors of Early and Late Recurrence After Definitive Radiotherapy for Nasopharyngeal Carcinoma
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53. MUC-1 aptamer conjugated InP/ZnS quantum dots/nanohydrogel fluorescent composite for mitochondria-mediated apoptosis in MCF-7 cells
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54. The Warburg Effect 97 Years after Its Discovery
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55. Lactate dehydrogenase inhibition affects homologous recombination repair independently of cell metabolic asset; implications for anticancer treatment
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56. Conformational features of lactate dehydrogenase: temperature effect in presence of small molecules, mathematical model
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57. Broad-complex transcription factor mediates opposing hormonal regulation of two phylogenetically distant arginine kinase genes in Tribolium castaneum
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58. FOXM1 Promotes the Warburg Effect and Pancreatic Cancer Progression via Transactivation of LDHA Expression
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59. Beyond the Warburg Effect: Oxidative and Glycolytic Phenotypes Coexist within the Metabolic Heterogeneity of Glioblastoma
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60. Targeting Cancer Metabolism and Current Anti-Cancer Drugs
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61. Warburg effect in keloids: A unique feature different from other types of scars
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62. Inhibition of LDH-A by Oxamate Enhances the Efficacy of Anti-PD-1 Treatment in an NSCLC Humanized Mouse Model
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63. Microarray Analysis of Novel Genes Involved in Nasopharyngeal Carcinoma
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64. Acetate Induces Growth Arrest in Colon Cancer Cells Through Modulation of Mitochondrial Function
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65. Targeting Mitochondria through the Use of Mitocans as Emerging Anticancer Agents
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66. Targeting lactate dehydrogenase a improves radiotherapy efficacy in non-small cell lung cancer: from bedside to bench
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67. Combination of Metformin, Sodium Oxamate and Doxorubicin Induces Apoptosis and Autophagy in Colorectal Cancer Cells via Downregulation HIF-1α
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68. Harnessing Lactate Metabolism for Radiosensitization
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69. Rapid and Highly Sensitive Electrochemical Technique for Cell Viability Assay via Monitoring of Intracellular NADH with New Double Mediator System
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70. Targeting the tumor metabolism by oxamate potentiates the impact of chemotherapeutics in colorectal cancer cells
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71. Metabolic Reprogramming and Immune Evasion in Nasopharyngeal Carcinoma
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72. An Insight to the Toxic Effect of Sulfamerazine on Porcine Pancreatic Amylase and Lactate Dehydrogenase Activity: An In Vitro Study
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73. Protein Lactylation Critically Regulates Energy Metabolism in the Protozoan Parasite Trypanosoma brucei
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74. Identification of the first highly selective inhibitor of human lactate dehydrogenase B
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75. Ribosomal Protein S6: A Potential Therapeutic Target against Cancer?
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76. LINC01128 facilitates the progression of pancreatic cancer through up-regulation of LDHA by targeting miR-561-5p.
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77. Oxamate Attenuates Glycolysis and ER Stress in Silicotic Mice
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78. Inhibition of LDHA suppresses cell proliferation and increases mitochondrial apoptosis via the JNK signaling pathway in cervical cancer cells
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79. Knockdown of Annexin A2 Enhances Radiosensitivity by Increasing G2/M-Phase Arrest, Apoptosis and Activating the p38 MAPK-HSP27 Pathway in Nasopharyngeal Carcinoma
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80. Knockdown or inhibition of arginine kinases enhances susceptibility of Tribolium castaneum to deltamethrin
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81. Lactic Acidosis in Patients with Solid Cancer.
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82. Associations between local acidosis induced by renal LDHA and renal fibrosis and mitochondrial abnormalities in patients with diabetic kidney disease
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83. Inhibiting Warburg Effect Can Suppress the Biological Activity and Secretion Function of Keloid Fibroblasts
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84. Targeting lactate-related cell cycle activities for cancer therapy
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85. Role of LDH in tumor glycolysis: Regulation of LDHA by small molecules for cancer therapeutics
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86. The Lactate and the Lactate Dehydrogenase in Inflammatory Diseases and Major Risk Factors in COVID-19 Patients
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87. Cisplatin-based concurrent chemoradiotherapy improved the survival of locoregionally advanced nasopharyngeal carcinoma after induction chemotherapy by reducing early treatment failure
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88. Clinical characteristics and prognostic factors affecting survival after radical radiotherapy for early and late post-treatment metastatic nasopharyngeal carcinoma
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89. NRF2 activation induces NADH-reductive stress, providing a metabolic vulnerability in lung cancer
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90. A triple-drug combination induces apoptosis in cervical cancer-derived cell lines
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91. Intra-Articular Lactate Dehydrogenase A Inhibitor Oxamate Reduces Experimental Osteoarthritis and Nociception in Rats via Possible Alteration of Glycolysis-Related Protein Expression in Cartilage Tissue
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92. The Presence of Pyruvate Carboxylase in the Human Brain and its Role in the Survival of Cultured Human Astrocytes
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93. Restoration of energy homeostasis under oxidative stress: Duo synergistic AMPK pathways regulating arginine kinases
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94. Cholesterol reprograms glucose and lipid metabolism to promote proliferation in colon cancer cells
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95. Targeting the lactic acid metabolic pathway for antitumor therapy
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96. Targeting acidic pre-metastatic niche in lungs by pH low insertion peptide and its utility for anti-metastatic therapy
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97. The effect of lactate dehydrogenase inhibitors on proliferation, motility and invasion of breast cancer cells in vitro highlights a new role for lactate
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98. ROLE OF CONTEMPORARY IMAGING METHODS IN RADIOTHERAPY PLANNING AND MONITORING OF GYNECOLOGICAL CANCER PATIENTS (REVIEW)
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99. The opposite role of lactate dehydrogenase a (LDHA) in cervical cancer under energy stress conditions
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100. Targeting metabolic reprogramming promotes the efficacy of transarterial chemoembolization in the rabbit VX2 liver tumor model
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101. Histone lactylation bridges metabolic reprogramming and epigenetic rewiring in driving carcinogenesis: Oncometabolite fuels oncogenic transcription
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102. Lactate dehydrogenase A is implicated in the pathogenesis of B‐cell lymphoma through regulation of the FER signaling pathway
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103. MicroRNAs as the critical regulators of epithelial mesenchymal transition in pancreatic tumor cells
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104. Inhibition of lactate dehydrogenase A by diclofenac sodium induces apoptosis in HeLa cells through activation of AMPK
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105. Glucose Metabolism and Glucose Transporters in Head and Neck Squamous Cell Carcinoma
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106. Lactate and lactylation in gastrointestinal cancer: Current progress and perspectives (Review)
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107. Delactylase effects of SIRT1 on a positive feedback loop involving the H19-glycolysis-histone lactylation in gastric cancer
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108. Dual inhibition of oxidative phosphorylation and glycolysis exerts a synergistic antitumor effect on colorectal and gastric cancer by creating energy depletion and preventing metabolic switch
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109. UBE2Q2 promotes tumor progression and glycolysis of hepatocellular carcinoma through NF-κB/HIF1α signal pathway
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