1. Mechanisms of Invasion in Head and Neck Cancer
    Lizandra Jimenez et al, 2015, Archives of Pathology & Laboratory Medicine CrossRef
  2. SOX2 Promotes the Epithelial to Mesenchymal Transition of Esophageal Squamous Cells by Modulating Slug Expression through the Activation of STAT3/HIF-α Signaling.
    Hui Gao et al, 2015, Int J Mol Sci CrossRef
  3. Functional significance of the long non-coding RNA RP11-169D4.1 as a metastasis suppressor in laryngeal squamous cell carcinoma by regulating CDH1
    Jing Zhao et al, 2017 CrossRef
  4. Roles of sex-determining region Y-box 2 in cell pluripotency and tumor-related signaling pathways
    JINGJIE WANG et al, 2015 CrossRef
  5. Cyclic mechanical stretching promotes migration but inhibits invasion of rat bone marrow stromal cells
    Bingyu Zhang et al, 2015, Stem Cell Research CrossRef
  6. Podocalyxin promotes glioblastoma multiforme cell invasion and proliferation by inhibiting angiotensin-(1-7)/Mas signaling
    BO LIU et al, 2015 CrossRef
  7. Cancer cell reprogramming to identify the genes competent for generating liver cancer stem cells
    Kenly Wuputra et al, 2017, Inflamm Regener CrossRef
  8. Toxicological effects of NCKU-21, a phenanthrene derivative, on cell growth and migration of A549 and CL1-5 human lung adenocarcinoma cells
    Hsien-Feng Liao et al, 2017, PLoS ONE CrossRef
  9. Chelerythrine inhibits human hepatocellular carcinoma metastasis in vitro
    Yuanzhang Zhu et al, 2018, Biological & Pharmaceutical Bulletin CrossRef
  10. Sinulariolide Suppresses Cell Migration and Invasion by Inhibiting Matrix Metalloproteinase-2/-9 and Urokinase through the PI3K/AKT/mTOR Signaling Pathway in Human Bladder Cancer Cells.
    Te-Chih Cheng et al, 2017, Mar Drugs CrossRef
  11. Silencing SOX2 Expression by RNA Interference Inhibits Proliferation, Invasion and Metastasis, and Induces Apoptosis through MAP4K4/JNK Signaling Pathway in Human Laryngeal Cancer TU212 Cells
    Ning Yang et al, 2015, J Histochem Cytochem. CrossRef
  12. Flaccidoxide-13-Acetate Extracted from the Soft Coral Cladiella kashmani Reduces Human Bladder Cancer Cell Migration and Invasion through Reducing Activation of the FAK/PI3K/AKT/mTOR Signaling Pathway
    Choo-Aun Neoh et al, 2017, Molecules CrossRef
  13. Metformin inhibits endothelial progenitor cell migration by decreasing matrix metalloproteinases, MMP-2 and MMP-9, via the AMPK/mTOR/autophagy pathway
    Wen-Dong Li et al, 2017 CrossRef
  14. Downregulation of miRNA-26b inhibits cancer proliferation of laryngeal carcinoma through autophagy by targeting ULK2 and inactivation of the PTEN/AKT pathway
    Shujing Wang et al, 2017 CrossRef
  15. MicroRNA-21 promotes migration and invasion of glioma cells via activation of Sox2 and β-catenin signaling
    Guoxuan Luo et al, 2017 CrossRef
  16. miR-218 inhibits the invasion and migration of colon cancer cells by targeting the PI3K/Akt/mTOR signaling pathway
    XIANGLIANG ZHANG et al, 2015 CrossRef
  17. The ginsenoside metabolite compound K inhibits growth, migration and stemness of glioblastoma cells
    Sanghun Lee et al, 2017 CrossRef
  18. Matrix stiffness regulates the proliferation, stemness and chemoresistance of laryngeal squamous cancer cells
    Lian Hui et al, 2017 CrossRef
  19. HOXC6 promotes gastric cancer cell invasion by upregulating the expression of MMP9
    Shi-Wei Chen et al, 2016 CrossRef
  20. 11-epi-Sinulariolide Acetate Reduces Cell Migration and Invasion of Human Hepatocellular Carcinoma by Reducing the Activation of ERK1/2, p38MAPK and FAK/PI3K/AKT/mTOR Signaling Pathways
    Jen-Jie Lin et al, 2014, Marine Drugs CrossRef
  21. Salivary gland stem cells: A review of development, regeneration and cancer
    Elaine Emmerson et al, 2018, genesis CrossRef
  22. Loss of SOX2 expression induces cell motility via vimentin up-regulation and is an unfavorable risk factor for survival of head and neck squamous cell carcinoma
    Pilar Bayo et al, 2015 CrossRef
  23. Bioinformatics analysis to identify action targets in NCI-N87 gastric cancer cells exposed to quercetin
    Yun Zeng et al, 2018, Pharmaceutical Biology CrossRef
  24. Targeting SOX2 in anticancer therapy.
    Laura Hüser et al, 2018, Expert Opin Ther Targets CrossRef
  25. Spondin-2 is a novel diagnostic biomarker for laryngeal squamous cell carcinoma
    Haosheng Ni et al, 2018, Pathology - Research and Practice CrossRef
  26. Tra2β silencing suppresses cell proliferation in laryngeal squamous cell carcinoma via inhibiting PI3K/AKT signaling
    Hao-Sheng Ni et al, 2018, The Laryngoscope CrossRef
  27. Sex-determining Region of Y Chromosome-related High-mobility-group Box 2 in Malignant Tumors
    Shi-Guang Cao et al, 2015, Chinese Medical Journal CrossRef
  28. Involvement of endoplasmic reticulum stress in regulation of endometrial stromal cell invasiveness: possible role in pathogenesis of endometriosis
    JongYeob Choi et al, 2019 CrossRef
  29. High expression level of SOX2 is significantly associated with shorter survival in patients with thymic epithelial tumors
    Guk Jin Lee et al, 2019, Lung Cancer CrossRef
  30. Metformin treatment alleviates polycystic ovary syndrome by decreasing the expression of MMP‐2 and MMP‐9 via H19/miR‐29b‐3p and AKT/mTOR/autophagy signaling pathways
    Zhilan Chen et al, 2019, J Cell Physiol CrossRef
  31. PRL-3 activates mTORC1 in Cancer Progression
    Zu Ye et al, 2015, Sci Rep CrossRef
  32. Metastatic potential and prognostic significance of SOX2: A meta-analysis
    Arslaan Javaeed et al, 2019, WJCO CrossRef
  33. Cancer Stem Cell–Suppressing Activity of Chrysotoxine, a Bibenzyl from Dendrobium pulchellum
    Narumol Bhummaphan et al, 2018, J Pharmacol Exp Ther CrossRef
  34. Curcumin inhibits the proliferation and invasiveness of MHCC97-H cells via p38 signaling pathway.
    Kai Zhang et al, 2014, Drug Dev. Res. CrossRef
  35. SOX 1, contrary to SOX 2, suppresses proliferation, migration, and invasion in human laryngeal squamous cell carcinoma by inhibiting the Wnt/β-catenin pathway
    Ning Yang et al, 2015, Tumor Biol. CrossRef
  36. Autophagy inhibits endothelial progenitor cells migration via the regulation of MMP2, MMP9 and uPA under normoxia condition.
    Wen-Dong Li et al, 0 CrossRef
  37. Effects of SOX2 on Proliferation, Migration and Adhesion of Human Dental Pulp Stem Cells
    Pengfei Liu et al, 2015, PLoS ONE CrossRef
  38. TGF-βinduces SOX2 expression in a time-dependent manner in human melanoma cells
    Kasia Weina et al, 2016, Pigment Cell Melanoma Res. CrossRef
  39. Yin Yang 1 is associated with cancer stem cell transcription factors (SOX2, OCT4, BMI1) and clinical implication.
    Samantha Kaufhold et al, 0 CrossRef
  40. Genomic Profile and BRCA-1 Promoter Methylation Status in BRCA Mutated Ovarian Cancer: New Insights in Predictive Biomarkers of Olaparib Response
    Elisena Franzese et al, 2019, Front. Oncol. CrossRef
  41. Epithelial-Mesenchymal Transition in Skin Cancers: A Review
    Anastasia Hodorogea et al, 2019, Analytical Cellular Pathology CrossRef
  42. TP3, an antimicrobial peptide, inhibits infiltration and motility of glioblastoma cells via modulating the tumor microenvironment
    Ying-Fa Chen et al, 2020, Cancer Med CrossRef
  43. Effect of 3q oncogenes SEC62 and SOX2 on lymphatic metastasis and clinical outcome of head and neck squamous cell carcinomas
    Florian Bochen et al, 2017, Oncotarget CrossRef
  44. CMV70-3P miRNA contributes to the CMV mediated glioma stemness and represents a target for glioma experimental therapy
    Ilya V. Ulasov et al, 2017, Oncotarget CrossRef
  45. SOX2 and cancer: current research and its implications in the clinic.
    Kasia Weina et al, 2014, Clin Transl Med CrossRef
  46. MiR-34c induces apoptosis and inhibits the viability of M4e cells by targeting BCL2
    Rui Li et al, 2017, Oncol Lett CrossRef
  47. Salidroside promotes human periodontal ligament cell proliferation and osteocalcin secretion via ERK1/2 and PI3K/Akt signaling pathways.
    Yukang Ying et al, 2018, Exp Ther Med CrossRef
  48. Differential expression of claudin‑4, occludin, SOX2 and proliferating cell nuclear antigen between basaloid squamous cell carcinoma and squamous cell carcinoma
    Fuyuki Sato et al, 2019, Mol Med Report CrossRef
  49. Downregulation of SOX3 leads to the inhibition of the proliferation, migration and invasion of osteosarcoma cells
    Yanjie Guo et al, 2018, Int J Oncol CrossRef
  50. Inhibition of Ezrin suppresses cell migration and invasion in human nasopharyngeal carcinoma
    Yuanyuan Tang et al, 2019, Oncol Lett CrossRef
  51. SOX2 knockdown inhibits the migration and invasion of basal cell carcinoma cells by targeting the SRPK1‑mediated PI3K/AKT signaling pathway
    Zhuo‑Ran Li et al, 2018, Oncol Lett CrossRef
  52. Functional characterization of SOX2 as an anticancer target
    Shizhen Zhang et al, 2020, Sig Transduct Target Ther CrossRef
  53. The deubiquitinase USP34 stabilizes SOX2 and induces cell survival and drug resistance in laryngeal squamous cell carcinoma
    Wei‐Li Dai et al, 2020, The Kaohsiung Journal of Medical Sciences CrossRef
  54. Relevance of iNOS expression in tumor growth and maintenance of cancer stem cells in a bladder cancer model
    Denise Belgorosky et al, 2020, J Mol Med CrossRef

  55. microRNA-139-3p Inhibits Malignant Behaviors of Laryngeal Cancer Cells via the KDM5B/SOX2 Axis and the Wnt/β-Catenin Pathway


    Yifei Ma et al, 2020, CMAR CrossRef
  56. Case report: 16-yr life history and genomic evolution of an ER+ HER2− breast cancer
    Bing Xu et al, 2020, Cold Spring Harb Mol Case Stud CrossRef
  57. PTCH1 regulates anchorage-independent growth and bone invasion of non-small cell lung cancer cells
    Ji-Yoon Choi et al, 2021, Bone CrossRef
  58. Targeting miRNAs with anesthetics in cancer: Current understanding and future perspectives
    Peyman Tabnak et al, 2021, Biomedicine & Pharmacotherapy CrossRef
  59. Ginsenoside Rg3 Alleviates Cisplatin Resistance of Gastric Cancer Cells Through Inhibiting SOX2 and the PI3K/Akt/mTOR Signaling Axis by Up-Regulating miR-429
    Xiaofeng Wang et al, 2022, Front. Genet. CrossRef
  60. The Effect of GPX2 on the Prognosis of Lung Adenocarcinoma Diagnosis and Proliferation, Migration, and Epithelial Mesenchymal Transition
    Yu-peng Li et al, 2022, Journal of Oncology CrossRef
  61. KRT17 Accelerates Cell Proliferative and Invasive Potential of Laryngeal Squamous Cell Carcinoma (LSCC) through Regulating AKT/mTOR and Wnt/β-Catenin Pathways
    JianQiu Wang et al, 2022, Evidence-Based Complementary and Alternative Medicine CrossRef
  62. SOX2 Promotes Invasion in Human Bladder Cancers through MMP2 Upregulation and FOXO1 Downregulation
    Qipeng Xie et al, 2022, IJMS CrossRef
  63. Impact of SOX2 function and regulation on therapy resistance in bladder cancer
    Guodong Chen et al, 2022, Front. Oncol. CrossRef
  64. Revisiting laminin and extracellular matrix remodeling in metastatic squamous cell carcinoma: What have we learned after more than four decades of research?
    John D Aleman et al, 2022, Mol Carcinog CrossRef
  65. null
    Said M. Afify et al, 2022 CrossRef
  66. SOX2-associated signaling pathways regulate biological phenotypes of cancers
    L.N. Ding et al, 2023, Biomedicine & Pharmacotherapy CrossRef
  67. How is the AKT/mTOR pathway involved in cell migration and invasion?
    JINGYAO XU et al, 2023 CrossRef
  68. The roles of the SOX2 protein in the development of esophagus and esophageal squamous cell carcinoma, and pharmacological target for therapy
    Jiaying Zhang et al, 2023, Biomedicine & Pharmacotherapy CrossRef
  69. Vitamin D inhibits osteosarcoma by reprogramming nonsense-mediated RNA decay and SNAI2-mediated epithelial-to-mesenchymal transition
    Enrico Capobianco et al, 2023, Front. Oncol. CrossRef
  70. SOX2 promotes a cancer stem cell-like phenotype and local spreading in oral squamous cell carcinoma
    Alessandro Sacco et al, 2023, PLoS ONE CrossRef
  71. Loss of monopolar spindle-binding protein 3B expression promotes colorectal cancer malignant behaviors by activation of target of rapamycin kinase/autophagy signaling
    Juan Sun et al, 2024, World J Gastroenterol CrossRef