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2. NLRP3 inflammasome activation promotes inflammation-induced carcinogenesis in head and neck squamous cell carcinoma
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3. In Search of a Converging Cellular Mechanism in Nanotoxicology and Nanomedicine in the Treatment of Cancer
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4. Resveratrol Attenuates Early Brain Injury after Experimental Subarachnoid Hemorrhage via Inhibition of NLRP3 Inflammasome Activation
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5. The IL-1 family of cytokines. Do they have a role in scleroderma fibrosis?
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6. NLRP3 Inflammasome Inhibition Attenuates Silica-Induced Epithelial to Mesenchymal Transition (EMT) in Human Bronchial Epithelial Cells
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7. Inflammasomes, the cardinal pathology mediators are activated by pathogens, allergens and mutagens: A critical review with focus on NLRP3
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8. Luteoloside Inhibits Proliferation and Promotes Intrinsic and Extrinsic Pathway-Mediated Apoptosis Involving MAPK and mTOR Signaling Pathways in Human Cervical Cancer Cells
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9. The correlation of NLRC3 expression to the progression and prognosis of hepatocellular carcinoma
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10. Lung Diseases
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11. Polydatin suppresses proliferation and metastasis of non-small cell lung cancer cells by inhibiting NLRP3 inflammasome activation via NF-κB pathway
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12. The Beta-Hydroxybutyrate Suppresses the Migration of Glioma Cells by Inhibition of NLRP3 Inflammasome
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13. Role of the NLRP3 inflammasome in cancer.
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14. Ergosterol peroxide from marine fungus Phoma sp. induces ROS-dependent apoptosis and autophagy in human lung adenocarcinoma cells
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15. Inflammasomes: Emerging Central Players in Cancer Immunology and Immunotherapy
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16. Growth of breast cancer cells by leptin is mediated via activation of the inflammasome: Critical roles of estrogen receptor signaling and reactive oxygen species production
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17. NLRP3 deletion inhibits inflammation-driven mouse lung tumorigenesis induced by benzo(a)pyrene and lipopolysaccharide
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18. Nox1/Ref-1-Mediated Activation of CREB Promotes Gremlin1-Driven Endothelial Cell Proliferation & Migration
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19. LXRα promotes cell metastasis by regulating the NLRP3 inflammasome in renal cell carcinoma
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20. miR-16 inhibits NLRP3 inflammasome activation by directly targeting TLR4 in acute lung injury
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21. Diverging inflammasome signals in tumorigenesis and potential targeting.
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22. Is mitochondrial dysfunction a driving mechanism linking COPD to nonsmall cell lung carcinoma?
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23. AIM2 promotes non-small-cell lung cancer cell growth through inflammasome-dependent pathway.
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24. NOD-like receptor signaling in inflammation-associated cancers: From functions to targeted therapies.
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25. The platelet NLRP3 inflammasome is upregulated in a murine model of pancreatic cancer and promotes platelet aggregation and tumor growth
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26. Correlation Between the NLRP3 Inflammasome and the Prognosis of Patients With LSCC
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27. The Multifaceted Roles of Pyroptotic Cell Death Pathways in Cancer
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28. Transcriptional regulation of inflammasome-associated pattern recognition receptors, and the relevance to disease pathogenesis
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29. Inflammasomes: Key Mediators of Lung Immunity
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30. Airborne particulate matter in vitro exposure induces cytoskeleton remodeling through activation of the ROCK-MYPT1-MLC pathway in A549 epithelial lung cells
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31. Is NLRP3 or NLRP6 inflammasome activation associated with inflammation-related lung tumorigenesis induced by benzo(a)pyrene and lipopolysaccharide?
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32. NLRP3 participates in the regulation of EMT in bleomycin-induced pulmonary fibrosis.
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33. The role of NLRP3 inflammasome in 5-fluorouracil resistance of oral squamous cell carcinoma.
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34. The association of aberrant expression of NLRP3 and p-S6K1 in colorectal cancer
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35. Opportunities and Challenges of the Human Microbiome in Ovarian Cancer
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36. Insulin-like growth factor-I activates NFκB and NLRP3 inflammatory signalling via ROS in cancer cells
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37. Caffeic Acid Phenethyl Ester Prevents Colitis-Associated Cancer by Inhibiting NLRP3 Inflammasome.
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38. Targeting CREB-binding protein overrides LPS induced radioresistance in non-small cell lung cancer cell lines
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39. Chikusetsu saponin IVa ameliorates high fat diet-induced inflammation in adipose tissue of mice through inhibition of NLRP3 inflammasome activation and NF-κB signaling
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40. Ginkgolide B inhibits lung cancer cells promotion via beclin-1-dependent autophagy
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41. The NLRP3 Inflammasome as a Critical Actor in the Inflammaging Process
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42. NLRP3 Inflammasome Activation in Cancer: A Double-Edged Sword
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43. NLRP3 in human glioma is correlated with increased WHO grade, and regulates cellular proliferation, apoptosis and metastasis via epithelial-mesenchymal transition and the PTEN/AKT signaling pathway
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44. Crystalline silica particles cause rapid NLRP3-dependent mitochondrial depolarization and DNA damage in airway epithelial cells
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45. NLRP3 Inflammasome From Bench to Bedside: New Perspectives for Triple Negative Breast Cancer
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46. Features of regulation and function of inflammasomes in inflammatory diseases of the female reproductive system
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47. AKT Regulates NLRP3 Inflammasome Activation by Phosphorylating NLRP3 Serine 5
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48. Serum amyloid A and inflammasome activation: A link to breast cancer progression?
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49. Inflammasome Activation in Pollution-Induced Skin Conditions
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50. NLRP3 inflammasome: a new therapeutic target for high-risk reproductive disorders?
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51. Therapeutic regulation of the NLRP3 inflammasome in chronic inflammatory diseases
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52. Role of the NLRP3 Inflammasome: Insights Into Cancer Hallmarks
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53. The Endocannabinoid, Anandamide, Acts as a Novel Inhibitor of LPS-Induced Inflammasome Activation in Human Gastric Cancer AGS Cell Line: Involvement of CB1 and TRPV1 Receptors
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54. Roles of Inflammasomes in Epstein–Barr Virus-Associated Nasopharyngeal Cancer
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55. The pyrin inflammasome aggravates inflammatory cell migration in patients with familial Mediterranean fever
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56. NLRP3 induces the autocrine secretion of IL-1β to promote epithelial–mesenchymal transition and metastasis in breast cancer
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57. Zerumbone Suppresses the LPS-Induced Inflammatory Response and Represses Activation of the NLRP3 Inflammasome in Macrophages
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58. Glyburide attenuates B(a)p and LPS ‐induced inflammation‐related lung tumorigenesis in mice
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59. Hedyotis diffusa plus Scutellaria barbata Suppress the Growth of Non-Small-Cell Lung Cancer via NLRP3/NF-Κb/MAPK Signaling Pathways
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60. NLRP3 Inflammasome Promotes the Progression of Acute Myeloid Leukemia via IL-1β Pathway
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61. Pyroptosis in Cancer: Friend or Foe?
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62. Salidroside Suppresses the Proliferation and Migration of Human Lung Cancer Cells through AMPK-Dependent NLRP3 Inflammasome Regulation
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63. A novel pyroptosis-related lncRNA signature for prognostic prediction in patients with lung adenocarcinoma.
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64. Identification and Validation of the Pyroptosis-Related Molecular Subtypes of Lung Adenocarcinoma by Bioinformatics and Machine Learning
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65. NLRP3 Inflammasome Activation Enhances ADK Expression to Accelerate Epilepsy in Mice
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66. A Novel Pyroptosis-Related Signature for Predicting Prognosis and Indicating Immune Microenvironment Features in Osteosarcoma
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67. Ketoprofen and Loxoprofen Platinum(IV) Complexes Displaying Antimetastatic Activities by Inducing DNA Damage, Inflammation Suppression, and Enhanced Immune Response
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69. An Integrative Network Approach to Identify Common Genes for the Therapeutics in Tuberculosis and Its Overlapping Non-Communicable Diseases
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70. The role of α5-nicotinic acetylcholine receptor/NLRP3 signaling pathway in lung adenocarcinoma cell proliferation and migration
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71. The Interplay of Hypoxia Signaling on Mitochondrial Dysfunction and Inflammation in Cardiovascular Diseases and Cancer: From Molecular Mechanisms to Therapeutic Approaches
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72. Identification of a novel prognostic signature related to PANoptosis and its regulatory mechanism as well as targeted treatment of active ingredients and traditional Chinese medicine in lung adenocarcinoma
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73. Pan-cancer analyses of pyroptosis with functional implications for prognosis and immunotherapy in cancer
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74. The role of pyroptosis in lung cancer and compounds regulated pyroptosis of lung cancer cells
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75. Comprehensive molecular analysis of a four-pyroptosis-gene signature with prognosis and immune landscape in lung adenocarcinoma
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77. Uterus globulin associated protein 1 (UGRP1) binds podoplanin (PDPN) to promote a novel inflammation pathway during Streptococcus pneumoniae infection.
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78. Mitophagy Induction and Aryl Hydrocarbon Receptor-Mediated Redox Signaling Contribute to the Suppression of Breast Cancer Cell Growth by Taloxifene via Regulation of Inflammasomes Activation
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79. Novel Inflammasome-Based Risk Score for Predicting Survival and Efficacy to Immunotherapy in Early-Stage Non-Small Cell Lung Cancer
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80. Ubiquitination as a key regulatory mechanism for O3-induced cutaneous redox inflammasome activation
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81. Signature based on RNA-binding protein-related genes for predicting prognosis and guiding therapy in non-small cell lung cancer
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82. Hesperetin from Root Extract of Clerodendrum petasites S. Moore Inhibits SARS-CoV-2 Spike Protein S1 Subunit-Induced NLRP3 Inflammasome in A549 Lung Cells via Modulation of the Akt/MAPK/AP-1 Pathway
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83. Design, Synthesis, and Biological Evaluation of Dual-Target COX-2/CYP51 Inhibitors for the Treatment of Fungal Infectious Diseases
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84. Neutrophil Extracellular Traps (NETs) Promote Non-Small Cell Lung Cancer Metastasis by Suppressing lncRNA MIR503HG to Activate the NF-κB/NLRP3 Inflammasome Pathway
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85. AIM2 upregulation promotes metastatic progression and PD‐L1 expression in lung adenocarcinoma
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86. MiR-223-3p attenuates the migration and invasion of NSCLC cells by regulating NLRP3
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87. Uncovering the Anticancer Potential of Polydatin: A Mechanistic Insight.
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89. Differential expression of immune-regulatory proteins C5AR1, CLEC4A and NLRP3 on peripheral blood mononuclear cells in early-stage non-small cell lung cancer patients
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91. Tumor-intrinsic NLRP3-HSP70-TLR4 axis drives premetastatic niche development and hyperprogression during anti–PD-1 immunotherapy
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93. Implications of reactive oxygen species in lung cancer and exploiting it for therapeutic interventions
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96. Myeloid-cell-specific role of Gasdermin D in promoting lung cancer progression in mice
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98. Inflammasomes driven inflammation in lung cancer revisited: a short review
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99. Involvement of inflammasomes in tumor microenvironment and tumor therapies
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102. NLRP3 inflammasome-induced pyroptosis in digestive system tumors
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103. Pyroptosis and its role in cancer
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104. Progress in the study of molecular mechanisms of cell pyroptosis in tumor therapy
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105. Pyroptosis: A promising target for lung cancer therapy
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106. Pyroptosis-related genes prognostic model for predicting targeted therapy and immunotherapy response in soft tissue sarcoma
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107. Targeting Spike Glycoprotein S1 Mediated by NLRP3 Inflammasome Machinery and the Cytokine Releases in A549 Lung Epithelial Cells by Nanocurcumin
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108. Clonal Hematopoiesis: Updates and Implications at the Solid Tumor-Immune Interface
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109. NR1D1 deficiency in the tumor microenvironment promotes lung tumor development by activating the NLRP3 inflammasome
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110. IL-17A functions and the therapeutic use of IL-17A and IL-17RA targeted antibodies for cancer treatment.
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111. Machine Learning-Based Integration Develops a Macrophage-Related Index for Predicting Prognosis and Immunotherapy Response in Lung Adenocarcinoma
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112. Pyroptosis: shedding light on the mechanisms and links with cancers
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113. New prospects of cancer therapy based on pyroptosis and pyroptosis inducers
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115. A novel necroptosis related gene signature and regulatory network for overall survival prediction in lung adenocarcinoma
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117. Screening of novel tumor-associated antigens for lung adenocarcinoma mRNA vaccine development based on pyroptosis phenotype genes
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118. Clinical-mediated discovery of pyroptosis in CD8+ T cell and NK cell reveals melanoma heterogeneity by single-cell and bulk sequence
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119. Crosstalk between hypoxia-induced pyroptosis and immune escape in cancer: from mechanisms to therapy
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