1. Escin induces caspase-dependent apoptosis and autophagy through the ROS/p38 MAPK signalling pathway in human osteosarcoma cells in vitro and in vivo
    Jian Zhu et al, 2017, Cell Death Dis CrossRef
  2. Molecular targets and anti-cancer potential of escin
    Dorothy H.J. Cheong et al, 2018, Cancer Letters CrossRef
  3. Bidesmosidic betulin saponin bearing L-rhamnopyranoside moieties induces apoptosis and inhibition of lung cancer cells growth in vitro and in vivo
    Mouadh Mihoub et al, 2018, PLoS ONE CrossRef
  4. In vitro ovicidal and larvicidal activities of some saponins and flavonoids against parasitic nematodes of goats
    Acidália Carine Vieira Santos et al, 2018, Parasitology CrossRef
  5. Escin-induced DNA damage promotes escin-induced apoptosis in human colorectal cancer cells via p62 regulation of the ATM/γH2AX pathway
    Zhong Wang et al, 2018, Acta Pharmacol Sin CrossRef
  6. Aescin-induced reactive oxygen species play a pro-survival role in human cancer cells via ATM/AMPK/ULK1-mediated autophagy
    Bin Li et al, 2018, Acta Pharmacol Sin CrossRef
  7. Escin induces apoptosis in human bladder cancer cells: An in vitro and in vivo study
    Chen-Li Cheng et al, 2018, European Journal of Pharmacology CrossRef
  8. Natural barrigenol–like triterpenoids: A comprehensive review of their contributions to medicinal chemistry
    Xinxin Zhang et al, 2019, Phytochemistry CrossRef
  9. Phytochemical, ethanomedicinal and pharmacological applications of escin from Aesculus hippocastanum L. towards future medicine
    Sahar Idris et al, 2020 CrossRef
  10. Natural Products Targeting the Mitochondria in Cancers.
    Yue Yang et al, 2020, Molecules CrossRef
  11. The Natural Product β-Escin Targets Cancer and Stromal Cells of the Tumor Microenvironment to Inhibit Ovarian Cancer Metastasis
    Hilary A. Kenny et al, 2021, Cancers CrossRef
  12. Preparation of a Horse Chestnut Extract with a 50% Content of Escin and its Actions on Tumor Cell Proliferation and Isolated Mitochondria
    T. A. Fedotcheva et al, 2019, Pharm Chem J CrossRef
  13. Escin Sodium Improves the Prognosis of Acute Pancreatitis via Promoting Cell Apoptosis by Suppression of the ERK/STAT3 Signaling Pathway
    Qian Zhang et al, 2021, Oxidative Medicine and Cellular Longevity CrossRef
  14. β-Escin reduces cancer progression in aggressive MDA-MB-231 cells by inhibiting glutamine metabolism through downregulation of c-myc oncogene
    Sakine AKAR et al, 2022, Mol Biol Rep CrossRef
  15. No Time to Die: How Kidney Cancer Evades Cell Death
    Carlo Ganini et al, 2022, IJMS CrossRef
  16. Phytochemicals for the Prevention and Treatment of Renal Cell Carcinoma: Preclinical and Clinical Evidence and Molecular Mechanisms
    Essa M. Bajalia et al, 2022, Cancers CrossRef
  17. Natural products as chemo-radiation therapy sensitizers in cancers
    Sabah Nisar et al, 2022, Biomedicine & Pharmacotherapy CrossRef
  18. Aesculus hippocastanum L.
    Sefa Gözcü, 2022 CrossRef
  19. UNDERSTANDING MECHANISTIC ASPECTS AND THERAPEUTIC POTENTIAL OF NATURAL SUBSTANCES AS ANTICANCER AGENTS
    Aakash Deep et al, 2023, Phytomedicine Plus CrossRef
  20. Escin’s Multifaceted Therapeutic Profile in Treatment and Post-Treatment of Various Cancers: A Comprehensive Review
    Sunnatullo Fazliev et al, 2023, Biomolecules CrossRef
  21. Role of Escin in breast cancer therapy: potential mechanism for inducing ferroptosis and synergistic antitumor activity with cisplatin
    Chenyuan Li et al, 2023, Apoptosis CrossRef
  22. The Effect of Diosmin, Escin, and Bromelain on Human Endothelial Cells Derived from the Umbilical Vein and the Varicose Vein—A Preliminary Study
    Lukasz Gwozdzinski et al, 2023, Biomedicines CrossRef
  23. Molecular regulation of autophagy and suppression of protein kinases by aescin, a triterpenoid saponin impedes lung cancer cell proliferation and mobility
    Jyoti Singh et al, 2023, International Journal of Biological Macromolecules CrossRef
  24. Escin enhanced the efficacy of sorafenib by autophagy‐mediated apoptosis in lung cancer cells
    Yusuf Hussain et al, 2023, Phytotherapy Research CrossRef
  25. Enhanced mitochondrial co-localization of β-escin micelle and pancreatic tumor accumulation relation
    Burcu Uner et al, 2023, Journal of Drug Delivery Science and Technology CrossRef
  26. Escin induces cell death in human skin melanoma cells through apoptotic mechanisms
    Canan Vejselova Sezer, 2024 CrossRef
  27. Natural Compounds Derived from Plants on Prevention and Treatment of Renal Cell Carcinoma: A Literature Review
    Zhenjie Yin et al, 2024, Advanced Biology CrossRef
  28. Current Trends in Herbal Medicines Targeting to Renal Cell Metabolic Pathways in the Treatment of Cancer
    Ashish Majumdar et al, 2024, Pharmacological Research - Natural Products CrossRef