Early Online

Open Access

Connexin 43 in splenic lymphocytes is involved in the regulation of CD4+CD25+ T lymphocyte proliferation and cytokine production in hypertensive inflammation

Hai-Chao Zhang, Zhong-Shuang Zhang, Liang Zhang, Ai Wang, He Zhu, Li Li, Jun-Qiang Si, Xin-Zhi Li, Ke-Tao Ma

Published online on: October 20, 2017

Effect on the dopaminergic metabolism induced by oral exposure to simazine during the prepubertal period in rats

Xueting Li, Jia Yu, Yanping Wu, Baixiang Li

Published online on: October 20, 2017

Antinociceptive effect of Valeriana fauriei regulates BDNF signaling in an animal model of fibromyalgia

Hwayoung Lee, Jiyun Im, Hansol Won, Jun Young Kim, Hyung‑Ki Kim, Jun‑Tack Kwon, Young Ock Kim, Sanghyun Lee, Ik‑Hyun Cho, Sang Won Lee, Hak‑Jae Kim

Published online on: October 20, 2017
Open Access

Renoprotective effect of erythropoietin via modulation of the STAT6/MAPK/NF-κB pathway in ischemia/reperfusion injury after renal transplantation

Jinhua Zhang, Daqiang Zhao, Ning Na, Heng Li, Bin Miao, Liangqing Hong, Zhengyu Huang

Published online on: October 20, 2017

Persistent STAT5-mediated ROS production and involvement of aberrant p53 apoptotic signaling in the resistance of chronic myeloid leukemia to imatinib

Yanhong Cheng, Yingchan Hao, Aimei Zhang, Chaojie Hu, Xiaoxiao Jiang, Quan Wu, Xiucai Xu

Published online on: October 20, 2017
Open Access

A novel method of neural differentiation of PC12 cells by using Opti-MEM as a basic induction medium

Rendong Hu, Qiaoyu Cao, Zhongqing Sun, Jinying Chen, Qing Zheng, Fei Xiao

Published online on: October 19, 2017

CCDC134 serves a crucial role in embryonic development

Biaoyi Yu, Tianzhuo Zhang, Peng Xia, Xiaoting Gong, Xiaoyan Qiu, Jing Huang

Published online on: October 19, 2017

Inhibition of Rho kinase protects against colitis in mice by attenuating intestinal epithelial barrier dysfunction via MLC and the NF-κB pathway

Yanting Zou, Lili Ma, Yuan Zhao, Shuncai Zhang, Chaohui Zhou, Yu Cai

Published online on: October 19, 2017
Open Access

Metabolic profiles of adipose-derived and bone marrow-derived stromal cells from elderly coronary heart disease patients by capillary liquid chromatography quadrupole time-of-flight mass spectrometry

Jian-Zhong Li, Hui Qu, Jian Wu, Fan Zhang, Zhi-Bo Jia, Jian-Yong Sun, Bo Lv, Yue Kang, Shu-Lin Jiang, Kai Kang

Published online on: October 19, 2017
Open Access

Induced pluripotent stem cell-conditioned medium suppresses pulmonary fibroblast-to-myofibroblast differentiation via the inhibition of TGF-β1/Smad pathway

Yan Zhou, Qiang Zhang, Yuan Gao, Mingqi Tan, Rui Zheng, Li Zhao, Xiaoye Zhang

Published online on: October 19, 2017
Open Access

Atorvastatin protects the proliferative ability of human umbilical vein endothelial cells inhibited by angiotensin II by changing mitochondrial energy metabolism

Ye Chang, Yuan Li, Ning Ye, Xiaofan Guo, Zhao Li, Guozhe Sun, Yingxian Sun

Published online on: October 19, 2017
Open Access

Altered expression profiles of circular RNA in colorectal cancer tissues from patients with lung metastasis

Yujian Zeng, Yu Xu, Ruo Shu, Liang Sun, Yan Tian, Chengmin Shi, Zhibin Zheng, Kunhua Wang, Huayou Luo

Published online on: October 16, 2017
Open Access

Hepatic differentiation of human iPSCs in different 3D models: A comparative study

Florian Meier, Nora Freyer, Joanna Brzeszczynska, Fanny Knöspel, Lyle Armstrong, Majlinda Lako, Selina Greuel, Georg Damm, Eva Ludwig-Schwellinger, Ulrich Deschl, James A. Ross, Mario Beilmann, Katrin Zeilinger

Published online on: October 16, 2017
Open Access

Hydrogen sulfide alleviates myocardial fibrosis in mice with alcoholic cardiomyopathy by downregulating autophagy

Biao Liang, Ting Xiao, Junrong Long, Maojun Liu, Zining Li, Shengquan Liu, Jun Yang

Published online on: October 16, 2017

DNA polymerase 5 acetylation by Eso1 is essential for Schizosaccharomyces pombe viability

Zhiming Chen, Hongshi Cao, Yingqiang Lu, Qiang Ren, Liankun Sun

Published online on: October 16, 2017

Protective effects of compounds from Garcinia mangostana L. (mangosteen) against UVB damage in HaCaT cells and hairless mice

A-Rang Im, Young-Mi Kim, Young-Won Chin, Sungwook Chae

Published online on: October 13, 2017

Puerarin attenuates the daunorubicin-induced apoptosis of H9c2 cells by activating the PI3K/Akt signaling pathway via the inhibition of Ca2+ influx

Weihua Li, Min Lu, Yanhong Zhang, Danqin Xia, Zebin Chen, Linhua Wang, Nina Yin, Zhigang Wang

Published online on: October 12, 2017

Prospective lncRNA-miRNA-mRNA regulatory network of long non-coding RNA LINC00968 in non-small cell lung cancer A549 cells: A miRNA microarray and bioinformatics investigation

Dong-Yao Li, Wen-Jie Chen, Lei Luo, Yong-Kun Wang, Jun Shang, Yu Zhang, Gang Chen, Shi-Kang Li

Published online on: October 12, 2017

Anti-inhibitory potential of an ethanolic extract of Distromium decumbens on pro-inflammatory cytokine production in Pseudomonas aeruginosa lipopolysaccharide-stimulated nasal polyp-derived fibroblasts

Dae-Sung Lee, Chang-Min Lee, Seong Kook Park, Mi-Jin Yim, Jeong Min Lee, Grace Choi, Jong Su Yoo, Won-Kyo Jung, Saegwang Park, Su-Kil Seo, Won Sun Park, Il-Whan Choi

Published online on: October 11, 2017
Open Access

Black rice-derived anthocyanins inhibit HER-2-positive breast cancer epithelial-mesenchymal transition-mediated metastasis in vitro by suppressing FAK signaling

Jie Zhou, Yan-Feng Zhu, Xiang-Yan Chen, Bin Han, Fei Li, Jing-Yao Chen, Xiao-Li Peng, Li-Ping Luo, Wei Chen, Xiao-Ping Yu

Published online on: October 11, 2017

Transformation of liver cells by 3-methylcholanthrene potentiates oxidative stress via the downregulation of glutathione synthesis

Sou Hyun Kim, Dahye Yoon, Yun-Hee Lee, Jaewon Lee, Nam Deuk Kim, Suhkmann Kim, Young-Suk Jung

Published online on: October 11, 2017
Open Access

High-throughput sequencing reveals novel lincRNA in age-related cataract

Na Zhang, Chunmei Zhang, Xu Wang, Yanhua Qi

Published online on: October 11, 2017

Protective effects of neem (Azadirachta indica A. Juss.) leaf extract against cigarette smoke- and lipopolysaccharide-induced pulmonary inflammation

Jae-Won Lee, Hyung Won Ryu, So-Yeon Park, Hyun Ah Park, Ok-Kyoung Kwon, Heung Joo Yuk, Krishna K. Shrestha, Minwoo Park, Jung Hee Kim, Sangwoo Lee, Sei-Ryang Oh, Kyung-Seop Ahn

Published online on: October 10, 2017
Open Access

MicroRNA-125a-3p is involved in early behavioral disorders in stroke-afflicted rats through the regulation of Cadm2

Yuqing Liu, Yunjun Li, Zhenxing Ren, Wenwen Si, Yiwei Li, Gang Wei, Wenguang Zhao, Jianhong Zhou, Yage Tian, Dongfeng Chen

Published online on: October 10, 2017

The association of LMP7 and TAP2 gene polymorphisms with treatment response to interferon/ribavirin in patients with genotype 1 chronic hepatitis C

Feng Zang, Yinan Yao, Mei Liu, Haozhi Fan, Ming Yue, Mingzhu Chen, Jie Wang, Rongbin Yu, Peng Huang

Published online on: October 10, 2017

Phosphorylation of eIF2α suppresses cisplatin-induced p53 activation and apoptosis by attenuating oxidative stress via ATF4-mediated HO-1 expression in human renal proximal tubular cells

Sung-Min Ju, Yong-Seok Jo, Yoo-Min Jeon, Hyun-Ock Pae, Dae-Gill Kang, Ho-Sub Lee, Jun-Sang Bae, Byung-Hun Jeon

Published online on: October 10, 2017
Open Access

Vaspin protects against LPS‑induced ARDS by inhibiting inflammation, apoptosis and reactive oxygen species generation in pulmonary endothelial cells via the Akt/GSK‑3β pathway

Di Qi, Daoxin Wang, Chunrong Zhang, Xumao Tang, Jing He, Yan Zhao, Wang Deng, Xinyu Deng

Published online on: October 9, 2017
Open Access

Analysis of miRNA expression profiling in human umbilical vein endothelial cells affected by heat stress

Jie Liu, Guoguo Zhu, Siya Xu, Shixin Liu, Qiping Lu, Zhongzhi Tang

Published online on: October 5, 2017
Open Access

Internal driving factors leading to extrahepatic manifestation of the hepatitis C virus infection

Zhou-Yi Wu, Jian-Rui Li, Meng-Hao Huang, Jun-Jun Cheng, Hu Li, Jin-Hua Chen, Xiao-Qin Lv, Zong-Gen Peng, Jian-Dong Jiang

Published online on: October 5, 2017
Open Access

Cell-penetrating peptides and their utility in genome function modifications (Review)

Maciej Gagat, Wioletta Zielińska, Alina Grzanka

Published online on: October 4, 2017
Open Access

SOX4 arrests lung development in rats with hyperoxia‑induced bronchopulmonary dysplasia by controlling EZH2 expression

Bingting Pan, Xindong Xue, Dan Zhang, Mengyun Li, Jianhua Fu

Published online on: October 3, 2017
Open Access

Characterization of tree shrew (Tupaia belangeri) interleukin-6 and its expression pattern in response to exogenous challenge

Yuanyuan Han, Xiaomei Sun, Dexuan Kuang, Pinfen Tong, Caixia Lu, Wenguang Wang, Na Li, Yang Chen, Xiaoping Wang, Jiejie Dai, Huatang Zhang

Published online on: October 2, 2017

Insulin restores UCP3 activity and decreases energy surfeit to alleviate lipotoxicity in skeletal muscle

Wenjuan Tang, Sunyinyan Tang, Hongdong Wang, Zhijuan Ge, Dalong Zhu, Yan Bi

Published online on: October 2, 2017
Open Access

Transcription factors Nrf2 and NF-κB contribute to inflammation and apoptosis induced by intestinal ischemia-reperfusion in mice

Qing-Tao Meng, Rong Chen, Cheng Chen, Ke Su, Wei Li, Ling-Hua Tang, Hui-Min Liu, Rui Xue, Qian Sun, Yan Leng, Jia-Bao Hou, Yang Wu, Zhong-Yuan Xia

Published online on: October 2, 2017
Open Access

Expression, regulation and mechanism of action of the miR-17-92 cluster in tumor cells (Review)

Li-Li Fang, Xing-Hui Wang, Bao-Fei Sun, Xiao-Dong Zhang, Xu-Hui Zhu, Zi-Jiang Yu, Heng Luo

Published online on: September 29, 2017
Open Access

Crosstalk between TLR2 and Sphk1 in microglia in the cerebral ischemia/reperfusion-induced inflammatory response

Wei Sun, Zhaoming Ding, Shengjie Xu, Zhiqiang Su, Hulun Li

Published online on: September 29, 2017
Open Access

Rivaroxaban attenuates thrombosis by targeting the NF-κB signaling pathway in a rat model of deep venous thrombus

Junhao Ma, Xinxi Li, Yang Wang, Zhenwei Yang, Jun Luo

Published online on: September 29, 2017
Open Access

Hypothermia inhibits the proliferation of bone marrow-derived mesenchymal stem cells and increases tolerance to hypoxia by enhancing SUMOylation

Xiaozhi Liu, Wenbo Ren, Zhongmin Jiang, Zhiguo Su, Xiaofang Ma, Yanxia Li, Rongcai Jiang, Jianning Zhang, Xinyu Yang

Published online on: September 29, 2017
Open Access

Protective effect of autophagy in neural ischemia and hypoxia: Negative regulation of the Wnt/β-catenin pathway

Zhen-Yu Shi, Jie-Xin Deng, Su Fu, Lai Wang, Qiang Wang, Bin Liu, Yong-Qiang Li, Jin-Bo Deng

Published online on: September 28, 2017
Open Access

Angiogenic effects of apigenin on endothelial cells after hypoxia-reoxygenation via the caveolin-1 pathway

Fengxia Tu, Qiongyi Pang, Xiang Chen, Tingting Huang, Meixia Liu, Qiongxiang Zhai

Published online on: September 28, 2017
Open Access

Naringin inhibits vascular endothelial cell apoptosis via endoplasmic reticulum stress‑ and mitochondrial‑mediated pathways and promotes intraosseous angiogenesis in ovariectomized rats

Wen‑Ji Shangguan, Yue‑Hui Zhang, Zhan‑Chun Li, Lu‑Min Tang, Jiang Shao, He Li

Published online on: September 28, 2017
Open Access

Grape seed proanthocyanidins inhibit the proliferation, migration and invasion of tongue squamous cell carcinoma cells through suppressing the protein kinase B/nuclear factor-κB signaling pathway

Ninggang Yang, Jing Gao, Xin Cheng, Cuilan Hou, Yaya Yang, Yanxin Qiu, Mengrou Xu, Yuan Zhang, Shuangsheng Huang

Published online on: September 28, 2017
Open Access

Betulinic acid induces apoptosis by regulating PI3K/Akt signaling and mitochondrial pathways in human cervical cancer cells

Tao Xu, Qiuying Pang, Yang Wang, Xiufeng Yan

Published online on: September 28, 2017

RACK1 silencing attenuates renal fibrosis by inhibiting TGF-β signaling

Jie Feng, Liyi Xie, Ranran Kong, Yali Zhang, Kehui Shi, Wanhong Lu, Hongli Jiang

Published online on: September 27, 2017

RUNX3 plays an important role in mediating the BMP9-induced osteogenic differentiation of mesenchymal stem cells

Yufeng Wang, Qiaoling Feng, Caixia Ji, Xiaohua Liu, Li Li, Jinyong Luo

Published online on: September 27, 2017
Open Access

Astragaloside IV attenuates the H2O2-induced apoptosis of neuronal cells by inhibiting α-synuclein expression via the p38 MAPK pathway

Xiang Liu, Jun Zhang, Shibo Wang, Jinfu Qiu, Chao Yu

Published online on: September 27, 2017
Journal Cover

Print ISSN: 1107-3756
Online ISSN: 1791-244X

2016 Impact Factor: 2.341
Ranked #21/128 Medicine Research and Experimental
(total number of cites)

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