Journal Articles

Article

Overexpression of eukaryotic elongation factor eEF2 in gastrointestinal cancers and its involvement in G2/M progression in the cell cycle

Junya Nakamura, Sayaka Aoyagi, Isamu Nanchi, Shin-Ichi Nakatsuka, Erika Hirata, Shohei Shibata, Mari Fukuda, Yumiko Yamamoto, Ikuyo Fukuda, Naoya Tatsumi, Tazu Ueda, Fumihiro Fujiki, Masaya Nomura, Sumiyuki Nishida, Toshiaki Shirakata, Naoki Hosen, Akihoro Tsuboi, Yoshihiro Oka, Riichiro Nezu, Masaki Mori, Yuichiro Doki, Katsuyuki Aozasa, Haruo Sugiyama, Yusuke Oji

Pages: 1181-1189 Published online on: 01 May 2009
Article

Human keratinocytes derived from the bulge region of hair follicles are refractory to differentiation

Yusuke Sasahara, Yoshie Yoshikawa, Tomonori Morinaga, Yoshiro Nakano, Nozomi Kanazawa, Joji Kotani, Shin Kawamata, Yoshinobu Murakami, Katsuyuki Takeuchi, Chizuko Inoue, Yukio Kitano, Tomoko Hashimoto-Tamaoki

Pages: 1191-1199 Published online on: 01 May 2009
Article

Tumor initiating potential of side population cells in human gastric cancer

Kazumasa Fukuda, Yoshiro Saikawa, Masaki Ohashi, Koshi Kumagai, Masaki Kitajima, Hideyuki Okano, Yumi Matsuzaki, Yuko Kitagawa

Pages: 1201-1207 Published online on: 01 May 2009
Article

Stat3-siRNA induces Fas-mediated apoptosis in vitro and in vivo in breast cancer

Sateesh Kunigal, Sajani S. Lakka, Prasanna Kumar Sodadasu, Norman Estes, Jasti S. Rao

Pages: 1209-1220 Published online on: 01 May 2009
Article

Berberine inhibits p53-dependent cell growth through induction of apoptosis of prostate cancer cells

Myoung Suk Choi, Ju Hoon Oh, Sun Mi Kim, Hai Young Jung, Hwan Soo Yoo, Yong Moon Lee, Dong Cheul Moon, Sang Bae Han, Jin Tae Hong

Pages: 1221-1230 Published online on: 01 May 2009
Article Open Access

Adenovirus-mediated eukaryotic initiation factor 4E binding protein-1 in combination with rapamycin inhibits tumor growth of pancreatic ductal adenocarcinoma in vivo

Roshan Mishra, Masaki Miyamoto, Tatsuya Yoshioka, Keidai Ishikawa, Yoshiyuki Matsumura, Yasuhito Shoji, Kazuomi Ichinokawa, Tommo Itoh, Toshiaki Shichinohe, Satoshi Hirano, Satoshi Kondo

Pages: 1231-1240 Published online on: 01 May 2009
Article

Gene silencing of translationally controlled tumor protein (TCTP) by siRNA inhibits cell growth and induces apoptosis of human prostate cancer cells

Munirathinam Gnanasekar, Sivasakthivel Thirugnanam, Guoxing Zheng, Aoshuang Chen, Kalyanasundaram Ramaswamy

Pages: 1241-1246 Published online on: 01 May 2009
Article

Human precision-cut liver tumor slices as a tumor patient-individual predictive test system for oncolytic measles vaccine viruses

Martina Zimmermann, Sorin Armeanu, Irina Smirnow, Susan Kupka, Silvia Wagner, Manfred Wehrmann, Marianne G. Rots, Geny M.M. Groothuis, Thomas S. Weiss, Alfred Königsrainer, Michael Gregor, Michael Bitzer, Ulrich M. Lauer

Pages: 1247-1256 Published online on: 01 May 2009
Article

Immunohistochemical determination of the appropriate anti-hTERT antibodies for in situ detection of telomerase activity in frozen sections of head and neck squamous cell carcinomas and tumor margin tissues

Eva-Maria Fabricius, Ute Kruse-Boitschenko, Reem Khoury, Gustav-Paul Wildner, Jan-Dirk Raguse, Martin Klein

Pages: 1257-1279 Published online on: 01 May 2009
Article

Identification of proteins associated to multi-drug resistance in LoVo human colon cancer cells

Michele Visentin, Maria Paola Simula, Franca Sartor, Alessandra Petrucco, Valli De Re, Giuseppe Toffoli

Pages: 1281-1289 Published online on: 01 May 2009
Article

Tyrosine phosphorylation of PP2A is regulated by HER-2 signalling and correlates with breast cancer progression

Lee Lee Wong, Chan Fong Chang, Evelyn S.C. Koay, Daohai Zhang

Pages: 1291-1301 Published online on: 01 May 2009
Article

P-glycoprotein expression affects 18F-fluorodeoxyglucose accumulation in hepatocellular carcinoma in vivo and in vitro

Satoru Seo, Etsuro Hatano, Tatsuya Higashi, Akio Nakajima, Yuji Nakamoto, Masaharu Tada, Nobuyuki Tamaki, Keiko Iwaisako, Koji Kitamura, Iwao Ikai, Shinji Uemoto

Pages: 1303-1312 Published online on: 01 May 2009
Article

A novel germline mutation of hMLH1 in a Korean hereditary non-polyposis colorectal cancer family

Ki-Hwan Kim, Ju-Young Kim, Se-Ig Oh, Haing-Woon Baik, Dong-Wook Kang, Sung-Hee Jung, Jeong-Hoon Rho, In-Taek Hwang

Pages: 1313-1318 Published online on: 01 May 2009
Article

Curcumin blocks CCL2-induced adhesion, motility and invasion, in part, through down-regulation of CCL2 expression and proteolytic activity

Jeffery G. Herman, Henry L. Stadelman, Charles E. Roselli

Pages: 1319-1327 Published online on: 01 May 2009
Article

Bone marrow CFU-GM and human tumor xenograft efficacy of three antitumor nucleoside analogs

Rebecca G. Bagley, Stephanie Roth, Leslie S. Kurtzberg, Cecile Rouleau, Min Yao, Jennifer Crawford, Roy Krumbholz, Dennis Lovett, Steven Schmid, Beverly A. Teicher

Pages: 1329-1340 Published online on: 01 May 2009
Article Open Access

AMT: Preclinical pharmacology studies

Faiz Niazi, Joachim Drevs, Klaus Diergarten, Annette Dorn, Armin Maier, Heinz Herbert Fiebig, Eddy Bruyns, Jürgen Scheele

Pages: 1341-1352 Published online on: 01 May 2009
Article

Efficacy on anaplastic thyroid carcinoma of valproic acid alone or in combination with doxorubicin, a synthetic chenodeoxycholic acid derivative, or lactacystin

Tae Hyun Kim, Young Hyun Yoo, Do-Young Kang, Hongsuk Suh, Moon Ki Park, Ki-Jae Park, Sung-Heun Kim

Pages: 1353-1362 Published online on: 01 May 2009
Article

Down-regulation of hTERT expression plays an important role in 15-deoxy-Δ12,14-prostaglandin J2-induced apoptosis in cancer cells

Mikako Moriai, Naoki Tsuji, Daisuke Kobayashi, Kageaki Kuribayashi, Naoki Watanabe

Pages: 1363-1372 Published online on: 01 May 2009
Article

1-(3-C-Ethynyl-β-D-ribo-pentofuranosyl)cytosine (ECyd, TAS-106), a novel potent inhibitor of RNA polymerase, potentiates the cytotoxicity of CDDP in human cancer cells both in vitro and in vivo

Hiromi Kazuno, Akio Fujioka, Masakazu Fukushima, Yusuke Wataya, Akira Matsuda, Takuma Sasaki

Pages: 1373-1380 Published online on: 01 May 2009
Article

Sphere-forming stem-like cell populations with drug resistance in human sarcoma cell lines

Hiromasa Fujii, Kanya Honoki, Toshifumi Tsujiuchi, Akira Kido, Kazuhiro Yoshitani, Yoshinori Takakura

Pages: 1381-1386 Published online on: 01 May 2009
Article

Immunogenic properties of renal cell carcinoma and the pathogenesis of osteolytic bone metastases

Francesca Perut, Elisabetta Cenni, Ronald E. Unger, C. James Kirkpatrick, Armando Giunti, Nicola Baldini

Pages: 1387-1393 Published online on: 01 May 2009
Article Open Access

The MDM2 antagonist nutlin-3 sensitizes p53-null neuroblastoma cells to doxorubicin via E2F1 and TAp73

Susan K. Peirce, Harry W. Findley

Pages: 1395-1402 Published online on: 01 May 2009
Article

Down-regulation of myopodin expression reduces invasion and motility of PC-3 prostate cancer cells

Ariane De Ganck, Veerle De Corte, Erik Bruyneel, Marc Bracke, Joel Vandekerckhove, Jan Gettemans

Pages: 1403-1409 Published online on: 01 May 2009
Article

Transcriptional regulation of WNT2B based on the balance of Hedgehog, Notch, BMP and WNT signals

Masuko Katoh, Masaru Katoh

Pages: 1411-1415 Published online on: 01 May 2009
Article

Transcription factor YY1 expression in human gastrointestinal cancer cells

Dharmaraj Chinnappan, Dongmei Xiao, Anita Ratnasari, Chris Andry, Thomas C. King, H. Christian Weber

Pages: 1417-1423 Published online on: 01 May 2009
Article

High Cks1 expression in transgenic and carcinogen-initiated mammary tumors is not always accompanied by reduction in p27Kip1

Louise Westbrook, Harish N. Ramanathan, Tatyana Isayeva, Anshu Roy Mittal, Zhican Qu, Michael D. Johnson, Francis G. Kern, Selvarangan Ponnazhagan, Clinton J. Grubbs, Jaideep V. Thottassery

Pages: 1425-1431 Published online on: 01 May 2009
Article

Three-dimensional culture using a radial flow bioreactor induces matrix metalloprotease 7-mediated EMT-like process in tumor cells via TGFβ1/Smad pathway

Shun-Ichi Shibata, Hideki Marushima, Tadashi Asakura, Tomokazu Matsuura, Homare Eda, Katsuhiko Aoki, Hiroshi Matsudaira, Kazu Ueda, Kiyoshi Ohkawa

Pages: 1433-1448 Published online on: 01 May 2009
Article

Tumor initiating cancer stem cells from human breast cancer cell lines

Ji Seung Han, David L. Crowe

Pages: 1449-1453 Published online on: 01 May 2009
Article

Se-methylselenocysteine sensitized TRAIL-mediated apoptosis via down-regulation of Bcl-2 expression

Jung Tae Lee, Tae-Jin Lee, Jong-Wook Park, Taeg Kyu Kwon

Pages: 1455-1460 Published online on: 01 May 2009
Article

miR-145 inhibits breast cancer cell growth through RTKN

Shihua Wang, Chunjing Bian, Zhuo Yang, Ye Bo, Jing Li, Lifen Zeng, Hong Zhou, Robert Chunhua Zhao

Pages: 1461-1466 Published online on: 01 May 2009
Article

Nimesulide, a selective COX-2 inhibitor, acts synergistically with ionizing radiation against A549 human lung cancer cells through the activation of caspase-8 and caspase-3

Byeong Mo Kim, Juyoon Won, Kyung Ah Maeng, Young Soo Han, Yeon-Sook Yun, Sung Hee Hong

Pages: 1467-1473 Published online on: 01 May 2009
Journal Cover

Cover Legend PDF

May 2009
Volume 34 Issue 5

Print ISSN: 1019-6439
Online ISSN: 1791-2423

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