Primary primitive neuroectodermal tumor of the cervix: A report of two cases and review of the literature

  • Authors:
    • Xiaofeng Wang
    • Yan Gao
    • Yanning Xu
    • Yixin Liu
    • Pengpeng Qu
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  • Published online on: March 13, 2017     https://doi.org/10.3892/mco.2017.1193
  • Pages: 697-700
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Abstract

Peripheral primitive neuroectodermal tumor (PNET) of the cervix uteri is extremely rare. Two cases of PNET of the cervix are presented herein. Two female patients, aged 48 and 43 years, presented with irregular uterine bleeding over the course of 1 year, and increased urinary frequency for 1 month, respectively. On gynecological examination, a mass in the cervix was palpated and a biopsy performed. The findings of the initial biopsy revealed small‑cell carcinoma in both patients. Following neoadjuvant chemotherapy and radiotherapy, radical hysterectomy was performed in both patients. One patient received 5 courses of consolidation chemotherapy and postoperative radiotherapy, whereas the other patient received 1 course of consolidation chemotherapy. At the time of the article submission, both patients remained disease-free at 27 and 12 months, respectively, after their initial diagnosis. Only a limited number of cases of PNET of the cervix uteri have been reported in the literature to date. Multimodal therapies, including total excision, adjuvant chemotherapy and/or radiotherapy, have been adopted to treat patients with PNET of the cervix.
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May-2017
Volume 6 Issue 5

Print ISSN: 2049-9450
Online ISSN:2049-9469

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Spandidos Publications style
Wang X, Gao Y, Xu Y, Liu Y and Qu P: Primary primitive neuroectodermal tumor of the cervix: A report of two cases and review of the literature. Mol Clin Oncol 6: 697-700, 2017
APA
Wang, X., Gao, Y., Xu, Y., Liu, Y., & Qu, P. (2017). Primary primitive neuroectodermal tumor of the cervix: A report of two cases and review of the literature. Molecular and Clinical Oncology, 6, 697-700. https://doi.org/10.3892/mco.2017.1193
MLA
Wang, X., Gao, Y., Xu, Y., Liu, Y., Qu, P."Primary primitive neuroectodermal tumor of the cervix: A report of two cases and review of the literature". Molecular and Clinical Oncology 6.5 (2017): 697-700.
Chicago
Wang, X., Gao, Y., Xu, Y., Liu, Y., Qu, P."Primary primitive neuroectodermal tumor of the cervix: A report of two cases and review of the literature". Molecular and Clinical Oncology 6, no. 5 (2017): 697-700. https://doi.org/10.3892/mco.2017.1193