Synchronous multiple primary gallbladder and gastric malignancies: Report of two cases and review of the literature

  • Authors:
    • Shuo Zhou
    • Zheng Lu
    • Hua Wu
    • Cong‑You Gu
    • Deng‑Yong Zhang
    • Wan‑Liang Sun
    • Xiang Ma
    • Hui‑Chun Liu
  • View Affiliations

  • Published online on: August 28, 2017     https://doi.org/10.3892/mco.2017.1397
  • Pages: 869-873
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Abstract

Multiple primary malignancies (MPM) are rare. In particular, synchronous gallbladder and gastric malignancies are extremely rare, are associated with a concealed onset and atypical symptoms, and are highly likely to be overlooked or misdiagnosed. The clinical data of two patients with synchronous gallbladder and gastric malignancies are herein reported and integrated with the relevant literature to retrospectively analyze and summarize the pathogenesis and clinical characteristics of MPM. Case 1 was a male 46‑year‑old patient who underwent laparoscopic cholecystectomy, and succumbed to extensive tumor metastasis 2 months after the operation. Case 2 was an 80‑year‑old female patient who was treated with distal gastrectomy for gastric cancer, cholecystectomy, gastrojejunostomy and dissection of 5 suprapyloric, 6 subpyloric, 7 left gastric and 8 common hepatic artery lymph nodes, and succumbed to multiple organ failure induced by extensive tumor invasion within 1 week after the operation. Clinical physicians must pay closer attention to early symptoms of MPM in order to make an accurate diagnosis, perform timely radical surgical treatment and achieve favorable therapeutic outcomes, in terms of significantly increasing long‑term patient survival rates.

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November-2017
Volume 7 Issue 5

Print ISSN: 2049-9450
Online ISSN:2049-9469

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Spandidos Publications style
Zhou S, Lu Z, Wu H, Gu CY, Zhang DY, Sun WL, Ma X and Liu HC: Synchronous multiple primary gallbladder and gastric malignancies: Report of two cases and review of the literature. Mol Clin Oncol 7: 869-873, 2017
APA
Zhou, S., Lu, Z., Wu, H., Gu, C., Zhang, D., Sun, W. ... Liu, H. (2017). Synchronous multiple primary gallbladder and gastric malignancies: Report of two cases and review of the literature. Molecular and Clinical Oncology, 7, 869-873. https://doi.org/10.3892/mco.2017.1397
MLA
Zhou, S., Lu, Z., Wu, H., Gu, C., Zhang, D., Sun, W., Ma, X., Liu, H."Synchronous multiple primary gallbladder and gastric malignancies: Report of two cases and review of the literature". Molecular and Clinical Oncology 7.5 (2017): 869-873.
Chicago
Zhou, S., Lu, Z., Wu, H., Gu, C., Zhang, D., Sun, W., Ma, X., Liu, H."Synchronous multiple primary gallbladder and gastric malignancies: Report of two cases and review of the literature". Molecular and Clinical Oncology 7, no. 5 (2017): 869-873. https://doi.org/10.3892/mco.2017.1397