A rare case of advanced lung cancer presenting as a symptomatic gastric tumor

  • Authors:
    • Cornelia Nitipir
    • Octav Ginghina
    • Liliana Popa
    • Florin Andrei
    • Nicolaie Tudor
    • Irina Radu
    • Cristian Iaciu
    • Cristina Orlov
    • Florina Vasilescu
    • Cristian Balalau
    • Grigoris Leon
    • Carolina Negrei
    • Maria Alexandra Barbu
  • View Affiliations

  • Published online on: February 2, 2018     https://doi.org/10.3892/mco.2018.1565
  • Pages: 595-599
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Abstract

Although gastric metastases have been estimated to occur in less than 2% of cancer patients, an increased use of upper digestive tract endoscopy allows for a higher detection of secondary gastric tumors. We describe the case of a 66-year-old male patient presenting with mild pain in the sternum and upper abdominal area. Physical examination revealed a right parietal skull tumor, with no other significant clinical changes. Upon exclusion of an acute coronary syndrome, upper digestive tract endoscopy was performed, showing the presence of an ulcerated tumor located in the gastric fundus. Histopathologic examination of the biopsy sample and immunohistochemical tests suggested a pulmonary origin of the gastric tumor. Whole body computer tomography showed the presence of tumors in the gastric fundus, left lung, liver, kidneys, bones and brain. Transbronchial biopsy of the lung tumor certified the diagnosis of non-small cell lung cancer, with the same immunohistochemical profile as the gastric tumor. Hence, it was considered the origin of the metastases. Biopsy of the skull tumor also had the identical tumor histology. Whole brain radiotherapy was performed for the brain metastases and subsequent chemotherapy was administered. Although non-specific, gastrointestinal signs and symptoms occurring in lung cancer patients should alert the clinicians as to the possibility of gastrointestinal metastases and prompt endoscopic evaluation.
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April-2018
Volume 8 Issue 4

Print ISSN: 2049-9450
Online ISSN:2049-9469

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Spandidos Publications style
Nitipir C, Ginghina O, Popa L, Andrei F, Tudor N, Radu I, Iaciu C, Orlov C, Vasilescu F, Balalau C, Balalau C, et al: A rare case of advanced lung cancer presenting as a symptomatic gastric tumor. Mol Clin Oncol 8: 595-599, 2018
APA
Nitipir, C., Ginghina, O., Popa, L., Andrei, F., Tudor, N., Radu, I. ... Barbu, M.A. (2018). A rare case of advanced lung cancer presenting as a symptomatic gastric tumor. Molecular and Clinical Oncology, 8, 595-599. https://doi.org/10.3892/mco.2018.1565
MLA
Nitipir, C., Ginghina, O., Popa, L., Andrei, F., Tudor, N., Radu, I., Iaciu, C., Orlov, C., Vasilescu, F., Balalau, C., Leon, G., Negrei, C., Barbu, M. A."A rare case of advanced lung cancer presenting as a symptomatic gastric tumor". Molecular and Clinical Oncology 8.4 (2018): 595-599.
Chicago
Nitipir, C., Ginghina, O., Popa, L., Andrei, F., Tudor, N., Radu, I., Iaciu, C., Orlov, C., Vasilescu, F., Balalau, C., Leon, G., Negrei, C., Barbu, M. A."A rare case of advanced lung cancer presenting as a symptomatic gastric tumor". Molecular and Clinical Oncology 8, no. 4 (2018): 595-599. https://doi.org/10.3892/mco.2018.1565