Autophagy: A new treatment strategy for MSC-based therapy in acute kidney injury (Review)

  • Authors:
    • Haoyuan Jia
    • Yongmin Yan
    • Zhaofeng Liang
    • Nitin Tandra
    • Bin Zhang
    • Juanjuan Wang
    • Wenrong Xu
    • Hui Qian
  • View Affiliations

  • Published online on: December 19, 2017     https://doi.org/10.3892/mmr.2017.8311
  • Pages: 3439-3447
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Abstract

Acute kidney injury (AKI) is a common and serious medical condition associated with poor health outcomes. Autophagy is a conserved multistep pathway that serves a major role in many biological processes and diseases. Recent studies have demonstrated that autophagy is induced in proximal tubular cells during AKI. Autophagy serves a pro‑survival or pro‑death role under certain conditions. Furthermore, mesenchymal stem cells (MSCs) have therapeutic potential in the repair of renal injury. This review summarizes the recent progress on the role of autophagy in AKI and MSCs‑based therapy for AKI. Further research is expected to prevent and treat acute kidney injury.
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March-2018
Volume 17 Issue 3

Print ISSN: 1791-2997
Online ISSN:1791-3004

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Spandidos Publications style
Jia H, Yan Y, Liang Z, Tandra N, Zhang B, Wang J, Xu W and Qian H: Autophagy: A new treatment strategy for MSC-based therapy in acute kidney injury (Review). Mol Med Rep 17: 3439-3447, 2018
APA
Jia, H., Yan, Y., Liang, Z., Tandra, N., Zhang, B., Wang, J. ... Qian, H. (2018). Autophagy: A new treatment strategy for MSC-based therapy in acute kidney injury (Review). Molecular Medicine Reports, 17, 3439-3447. https://doi.org/10.3892/mmr.2017.8311
MLA
Jia, H., Yan, Y., Liang, Z., Tandra, N., Zhang, B., Wang, J., Xu, W., Qian, H."Autophagy: A new treatment strategy for MSC-based therapy in acute kidney injury (Review)". Molecular Medicine Reports 17.3 (2018): 3439-3447.
Chicago
Jia, H., Yan, Y., Liang, Z., Tandra, N., Zhang, B., Wang, J., Xu, W., Qian, H."Autophagy: A new treatment strategy for MSC-based therapy in acute kidney injury (Review)". Molecular Medicine Reports 17, no. 3 (2018): 3439-3447. https://doi.org/10.3892/mmr.2017.8311