1
|
Antoni S, Ferlay J, Soerjomataram I, Znaor
A, Jemal A and Bray F: Bladder cancer incidence and mortality: A
global overview and recent trends. Eur Urol. 71:96–108. 2017.
View Article : Google Scholar : PubMed/NCBI
|
2
|
Abufaraj M, Shariat SF, Haitel A, Moschini
M, Foerster B, Chłosta P, Gust K, Babjuk M, Briganti A, Karakiewicz
PI and Albrecht W: Prognostic role of N-cadherin expression in
patients with non-muscle-invasive bladder cancer. Urol Oncol.
35:264–271. 2017. View Article : Google Scholar : PubMed/NCBI
|
3
|
Liu CK, Chen Z, Fang J, Xu A, Zhang W and
Wang Z: H19-derived miR-675 contributes to bladder cancer cell
proliferation by regulating p53 activation. Tumor Biol. 37:263–270.
2016. View Article : Google Scholar
|
4
|
Liu J, Xu R and Zhao X: Mechanisms for
effect of osthole on inhibiting the growth and invasion of bladder
cancer cells. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 41:345–352.
2016.(In Chinese). PubMed/NCBI
|
5
|
Hashida H, Takabayashi A, Kanai M, Adachi
M, Kondo K, Kohno N, Yamaoka Y and Miyake M: Aminopeptidase N is
involved in cell motility and angiogenesis: Its clinical
significance in human colon cancer. Gastroenterology. 122:376–386.
2002. View Article : Google Scholar : PubMed/NCBI
|
6
|
Mina-Osorio P: The moonlighting enzyme
CD13: Old and new functions to target. Trends Mol Med. 14:361–371.
2008. View Article : Google Scholar : PubMed/NCBI
|
7
|
Ishii K, Usui S, Sugimura Y, Yoshida S,
Hioki T, Tatematsu M, Yamamoto H and Hirano K: Aminopeptidase N
regulated by zinc in human prostate participates in tumor cell
invasion. Int J Cancer. 92:49–54. 2001. View Article : Google Scholar : PubMed/NCBI
|
8
|
Fontijn D, Duyndam MC, van Berkel MP,
Yuana Y, Shapiro LH, Pinedo HM, Broxterman HJ and Boven E:
CD13/aminopeptidase N overexpression by basic fibroblast growth
factor mediates enhanced invasiveness of 1F6 human melanoma cells.
Br J Cancer. 94:1627–1636. 2006. View Article : Google Scholar : PubMed/NCBI
|
9
|
Wang X, Niu Z, Jia Y, Cui M, Han L, Zhang
Y, Liu Z, Bi D and Liu S: Ubenimex inhibits cell proliferation,
migration and invasion by inhibiting the expression of APN and
inducing autophagic cell death in prostate cancer cells. Oncol Rep.
35:2121–2130. 2016. View Article : Google Scholar : PubMed/NCBI
|
10
|
Maiuri MC, Zalckvar E, Kimchi A and
Kroemer G: Self-eating and self-killing: Crosstalk between
autophagy and apoptosis. Nat Rev Mol Cell Biol. 8:741–752. 2007.
View Article : Google Scholar : PubMed/NCBI
|
11
|
Horita H, Frankel AE and Thorburn A: Acute
myeloid leukemia-targeted toxin activates both apoptotic and
necroptotic death mechanisms. PLoS One. 3:e39092008. View Article : Google Scholar : PubMed/NCBI
|
12
|
Yuan CH, Horng CT, Lee CF, Chiang NN, Tsai
FJ, Lu CC, Chiang JH, Hsu YM, Yang JS and Chen FA: Epigallocatechin
gallate sensitizes cisplatin-resistant oral cancer CAR cell
apoptosis and autophagy through stimulating AKT/STAT3 pathway and
suppressing multidrug resistance 1 signaling. Environ Toxicol.
32:845–855. 2017. View Article : Google Scholar : PubMed/NCBI
|
13
|
Mujtaba SF, Dwivedi A, Yadav N, Ch R,
Kushwaha HN, Mudiam MK, Singh G and Ray RS: Superoxide mediated
photomodification and DNA damage induced apoptosis by
Benz(a)anthracene via mitochondrial mediated pathway. J Photochem
Photobiol B. 142:92–102. 2015. View Article : Google Scholar : PubMed/NCBI
|
14
|
Zhai B, Hu F, Jiang X, Xu J, Zhao D, Liu
B, Pan S, Dong X, Tan G, Wei Z, et al: Inhibition of Akt reverses
the acquired resistance to sorafenib by switching protective
autophagy to autophagic cell death in hepatocellular carcinoma. Mol
Cancer Ther. 13:1589–1598. 2014. View Article : Google Scholar : PubMed/NCBI
|
15
|
Wan J, Liu T, Mei L, Li J, Gong K, Yu C
and Li W: Synergistic antitumour activity of sorafenib in
combination with tetrandrine is mediated by reactive oxygen species
(ROS)/Akt signaling. Br J Cancer. 109:342–350. 2013. View Article : Google Scholar : PubMed/NCBI
|
16
|
Tsukamoto H, Shibata K, Kajiyama H,
Terauchi M, Nawa A and Kikkawa F: Aminopeptidase N (APN)/CD13
inhibitor, Ubenimex, enhances radiation sensitivity in human
cervical cancer. BMC Cancer. 8:742008. View Article : Google Scholar : PubMed/NCBI
|
17
|
Sekine K, Fujii H and Abe F: Induction of
apoptosis by bestatin (ubenimex) in human leukemic cell lines.
Leukemia. 13:729–734. 1999. View Article : Google Scholar : PubMed/NCBI
|
18
|
Liu S, Xie F, Wang H, Liu Z, Liu X, Sun L
and Niu Z: Ubenimex inhibits cell proliferation, migration and
invasion in renal cell carcinoma: The effect is
autophagy-associated. Oncol Rep. 33:1372–1380. 2015. View Article : Google Scholar : PubMed/NCBI
|
19
|
Liang W, Gao B, Xu G, Weng D, Xie M and
Qian Y: Possible contribution of aminopeptidase N (APN/CD13) to
migration and invasion of human osteosarcoma cell lines. Int J
Oncol. 45:2475–2485. 2014. View Article : Google Scholar : PubMed/NCBI
|
20
|
Li J, Wang X, Hou J, Huang Y, Zhang Y and
Xu W: Enhanced anticancer activity of 5-FU in combination with
Bestatin: Evidence in human tumor-derived cell lines and an H22
tumor-bearing mouse. Drug Discov Ther. 9:45–52. 2015. View Article : Google Scholar : PubMed/NCBI
|
21
|
Yamashita M, Wada H, Eguchi H, Ogawa H,
Yamada D, Noda T, Asaoka T, Kawamoto K, Gotoh K, Umeshita K, et al:
A CD13 inhibitor, ubenimex, synergistically enhances the effects of
anticancer drugs in hepatocellular carcinoma. Int J Oncol.
49:89–98. 2016. View Article : Google Scholar : PubMed/NCBI
|
22
|
Nohara S, Kato K, Fujiwara D, Sakuragi N,
Yanagihara K, Iwanuma Y and Kajiyama Y: Aminopeptidase N (APN/CD13)
as a target molecule for scirrhous gastric cancer. Clin Res Hepatol
Gastroenterol. 40:494–503. 2016. View Article : Google Scholar : PubMed/NCBI
|
23
|
Tokuhara T, Hattori N, Ishida H, Hirai T,
Higashiyama M, Kodama K and Miyake M: Clinical significance of
aminopeptidase N in non-small cell lung cancer. Clin Cancer Res.
12:3971–3978. 2006. View Article : Google Scholar : PubMed/NCBI
|
24
|
Pang L, Zhang N, Xia Y, Wang D, Wang G and
Meng X: Serum APN/CD13 as a novel diagnostic and prognostic
biomarker of pancreatic cancer. Oncotarget. 7:77854–77864. 2016.
View Article : Google Scholar : PubMed/NCBI
|
25
|
Kehlen A, Lendeckel U, Dralle H, Langner J
and Hoang-Vu C: Biological significance of aminopeptidase N/CD13 in
thyroid carcinomas. Cancer Res. 63:8500–8506. 2003.PubMed/NCBI
|
26
|
Wang SN, Yang SF, Tsai HH, Lee KT and Yeh
YT: Increased adiponectin associated with poor survival in
hepatocellular carcinoma. J Gastroenterol. 49:1342–1351. 2014.
View Article : Google Scholar : PubMed/NCBI
|
27
|
Mizushima N, Levine B, Cuervo AM and
Klionsky DJ: Autophagy fights disease through cellular
self-digestion. Nature. 451:1069–1075. 2008. View Article : Google Scholar : PubMed/NCBI
|
28
|
Yang ZJ, Chee CE, Huang S and Sinicrope F:
Autophagy modulation for cancer therapy. Cancer Biol Ther.
11:169–176. 2011. View Article : Google Scholar : PubMed/NCBI
|
29
|
Takeuchi H, Kondo Y, Fujiwara K, Kanzawa
T, Aoki H, Mills GB and Kondo S: Synergistic augmentation of
rapamycin-induced autophagy in malignant glioma cells by
phosphatidylinositol 3-kinase/protein kinase B inhibitors. Cancer
Res. 65:3336–3346. 2005. View Article : Google Scholar : PubMed/NCBI
|
30
|
Chen W, Wu J, Shi H, Wang Z, Zhang G, Cao
Y, Jiang C and Ding Y: Hepatic stellate cell coculture enables
sorafenib resistance in Huh7 cells through HGF/c-Met/Akt and
Jak2/Stat3 pathways. Biomed Res Int. 2014:7649812014.PubMed/NCBI
|
31
|
Song G, Ouyang G and Bao S: The activation
of Akt/PKB signaling pathway and cell survival. J Cell Mol Med.
9:59–71. 2005. View Article : Google Scholar : PubMed/NCBI
|
32
|
Yang L, Liu Y, Wang M, Qian Y, Dai X, Zhu
Y, Chen J, Guo S and Hisamitsu T: Celastrus orbiculatus extract
triggers apoptosis and autophagy via PI3K/Akt/mTOR inhibition in
human colorectal cancer cells. Oncol Lett. 12:3771–3778. 2016.
View Article : Google Scholar : PubMed/NCBI
|
33
|
Chang CH, Lee CY, Lu CC, Tsai FJ, Hsu YM,
Tsao JW, Juan YN, Chiu HY, Yang JS and Wang CC: Resveratrol-induced
autophagy and apoptosis in cisplatin-resistant human oral cancer
CAR cells: A key role of AMPK and Akt/mTOR signaling. Int J Oncol.
50:873–882. 2017. View Article : Google Scholar : PubMed/NCBI
|