Early Online

TGF‑β1 expression in adults with non‑traumatic osteonecrosis of the femoral head

Jun Tao, Bin Dong, Li‑Xin Yang, Ke‑Qing Xu, Shuai Ma, Jun Lu

Published online on: October 19, 2017
Open Access

Hepatic differentiation of mouse bone marrow‑derived mesenchymal stem cells using a novel 3D culture system

Qiong Wu, Jing Tang, Yi Li, Li Li, Yujia Wang, Ji Bao, Hong Bu

Published online on: October 19, 2017

miR-320a modulates cell growth and chemosensitivity via regulating ADAM10 in gastric cancer

Xiancai Ge, Haiyan Cui, Yanbing Zhou, Deying Yin, Yuanyuan Feng, Qun Xin, Xianhui Xu, Weijing Liu, Shanglong Liu, Qin Zhang

Published online on: October 19, 2017
Open Access

HMGA1 participates in MHCC97H cell proliferation and invasion through the ILK/Akt/GSK3β signaling pathway

Li Liu, Shuang Zhang, Lei Hu, Linhua Liu, Wuhua Guo, Jixiang Zhang

Published online on: October 19, 2017
Open Access

miR-214 promotes periodontal ligament stem cell osteoblastic differentiation by modulating Wnt/β‑catenin signaling

Fengdi Cao, Jialin Zhan, Xufeng Chen, Kai Zhang, Renfa Lai, Zhiqiang Feng

Published online on: October 19, 2017
Open Access

Naringin protects myocardial cells from doxorubicin‑induced apoptosis partially by inhibiting the p38MAPK pathway

Chun‑Yan Jian, Han‑Bin Ouyang, Xian‑Hong Xiang, Jia‑Li Chen, Yong‑Xin Li, Xin Zhou, Jin‑Yang Wang, Yang Yang, En‑Yi Zhong, Wen‑Hua Huang, Hong‑Wu Zhang

Published online on: October 19, 2017
Open Access

Therapeutic effects of STAT3 inhibition by nifuroxazide on murine acute graft graft-vs.-host disease: Old drug, new use

Huijie Jia, Jing Cui, Xiaolong Jia, Jingjing Zhao, Yuchen Feng, Peijuan Zhao, Dan Zang, Jian Yu, Tiesuo Zhao, Hui Wang, Kailin Xu

Published online on: October 19, 2017
Open Access

Tumor suppressive role of miR-194-5p in glioblastoma multiforme

Zhao Zhang, Bo Lei, Honggang Wu, Xiaoli Zhang, Niandong Zheng

Published online on: October 19, 2017
Open Access

Effects of WD‑3 on tumor growth and the expression of integrin αvβ3 and ERK1/2 in mice bearing human gastric cancer using the 18F‑RGD PET/CT imaging system

Chunhui Jin, Bao‑Nan Zhang, Zhipeng Wei, Bo Ma, Qi Pan, Pingping Hu

Published online on: October 19, 2017
Open Access

MicroRNA‑137 has a suppressive role in liver cancer via targeting EZH2

Shichang Cui, Yanlei Sun, Yang Liu, Chengbiao Liu, Jinbao Wang, Guang Hao, Qidong Sun

Published online on: October 19, 2017

MicroRNA‑216b inhibits cell proliferation and invasion in glioma by directly targeting metadherin

Zhihua Chen, Yaxiang Wu, Shuxin Song, Xingen Zhu, Jianming Zhu

Published online on: October 19, 2017
Open Access

Elaidic acid induces cell apoptosis through induction of ROS accumulation and endoplasmic reticulum stress in SH‑SY5Y cells

Wei‑Wei Ma, Lei Zhao, Lin‑Hong Yuan, Huan‑Ling Yu, Hui Wang, Xin‑Yuan Gong, Feng Wei, Rong Xiao

Published online on: October 19, 2017

Apolipoprotein status in type 2 diabetes mellitus and its complications (Review)

Puhong Zhang, Jialin Gao, Chun Pu, Yao Zhang

Published online on: October 19, 2017

Dihydroartemisinin treatment exhibits antitumor effects in glioma cells through induction of apoptosis

Chun‑Hua Xu, Yue Liu, Li‑Min Xiao, Chang‑Gui Guo, Su‑Yue Zheng, Er‑Ming Zeng, Dong‑Hai Li

Published online on: October 19, 2017
Open Access

Identification of key genes in glioma CpG island methylator phenotype via network analysis of gene expression data

Lijuan Bo, Bo Wei, Zhanfeng Wang, Daliang Kong, Zheng Gao, Zhuang Miao

Published online on: October 19, 2017
Open Access

Semi‑random mutagenesis profile of BCR‑ABL during imatinib resistance acquirement in K562 cells

Yan Dong, Xiaotong Gao, Yingxin Zhao, Mengying Wei, Lingmin Xu, Guodong Yang, Li Liu

Published online on: October 19, 2017
Open Access

Melatonin inhibits colon cancer RKO cell migration by downregulating Rho‑associated protein kinase expression via the p38/MAPK signaling pathway

Zhen Liu, Duobing Zou, Xiaoping Yang, Xiaolong Xue, Li  Zuo, Qing Zhou, Ruolei Hu, Yuan Wang

Published online on: October 19, 2017
Open Access

Nephrin loss is reduced by grape seed proanthocyanidins in the experimental diabetic nephropathy rat model

Xianhua Li, Zhaoli Gao, Haiqing Gao, Baoying Li, Tao Peng, Bei Jiang, Xiangdong Yang, Zhao Hu

Published online on: October 19, 2017

MicroRNA‑663 suppresses the proliferation and invasion of colorectal cancer cells by directly targeting FSCN1

Shaojun Yu, Haiting Xie, Jingjing Zhang, Da Wang, Yongmao Song, Suzhan Zhang, Shu Zheng, Jian Wang

Published online on: October 17, 2017
Open Access

MicroRNA‑218 promotes prostaglandin E2 to inhibit osteogenic differentiation in synovial mesenchymal stem cells by targeting 15‑hydroxyprostaglandin dehydrogenase [NAD(+)]

Ruijun Cong, Kun Tao, Peiliang Fu, Lieming Lou, Yuchang Zhu, Song Chen, Xinyu Cai, Lingzhou Mao

Published online on: October 17, 2017

Clinical implications of progranulin in gastric cancer and its regulation via a positive feedback loop involving AKT and ERK signaling pathways

Dong Yang, Ruidong Li, Huili Wang, Junye Wang, Lei Han, Lihua Pan, Xueqin Li, Qingli Kong, Guijuan Wang, Xiujun Su

Published online on: October 17, 2017

Leptin promotes IL‑18 secretion by activating the NLRP3 inflammasome in RAW 264.7 cells

Sisi Fu, Lei Liu, Lei Han, Yiyun Yu

Published online on: October 17, 2017

Expression of key enzymes in the mevalonate pathway are altered in monocrotaline-induced pulmonary arterial hypertension in rats

Dongmei Jiang, Yu Chen, Yuxiang Zhu, Guosheng Fu, Shiming Xu

Published online on: October 17, 2017
Open Access

Whole‑genome scale identification of methylation markers specific for cerebral palsy in monozygotic discordant twins

Zhe Jiao, Zhimei Jiang, Jingtao Wang, Hui Xu, Qiang Zhang, Shuang Liu, Ning Du, Yuanyuan Zhang, Hongbin Qiu

Published online on: October 17, 2017
Open Access

Elevated pentose phosphate pathway is involved in the recovery of hypoxia‑induced erythrocytosis

Chang Liu, Bao Liu, Er‑Long Zhang, Wen‑Ting Liao, Jie Liu, Bing‑Da Sun, Gang Xu, Jian Chen, Yu‑Qi Gao

Published online on: October 17, 2017

Inhibition of human lung cancer proliferation through targeting stromal fibroblasts by dihydromyricetin

Kai-Jie Fan, Bo Yang, Yang Liu, Xiao-Dong Tian, Bo Wang

Published online on: October 17, 2017

20-Hydroxyeicosatetraenoic acid regulates the expression of Nedd4‑2 in kidney and liver through a neddylation modification pathway

Jianzhu Zhao, Bijun Zhang, Guangrui Lai, Runhong Xu, Guoming Chu, Yanyan Zhao

Published online on: October 17, 2017

Protective effects of rosmarinic acid against hydrogen peroxide‑induced cellular senescence and the inflammatory response in normal human dermal fibroblasts

Hyung Jin Hahn, Ki Bbeum Kim, In‑Sook An, Kyu Joong Ahn, Hyun Joo Han

Published online on: October 17, 2017
Open Access

Identification of genome variations in patients with lung adenocarcinoma using whole genome re‑sequencing

Guiyuan Li, Yunqing Mei, Fan Yang, Shengming Yi, Lemin Wang

Published online on: October 17, 2017

Juglone potentiates TRAIL‑induced apoptosis in human melanoma cells via activating the ROS‑p38‑p53 pathway

Xiao Liu, Yan Chen, Yaohua Zhang, Juan Du, Yubao Lv, Shuming Mo, Yingchao Liu, Feng Ding, Jinfeng Wu, Ji Li

Published online on: October 17, 2017
Open Access

Proteomic analysis of serum deprivation in tongue squamous cell carcinoma

Junfeng Zhang, Wei Dong, Yufen Meng, Miao Jiang, Zhen Zhan

Published online on: October 17, 2017
Open Access

MicroRNA-23a-3p inhibitor decreases osteonecrosis incidence in a rat model

Yulei Dong, Tao Li, Yulong Li, Shaoda Ren, Junfen Fan, Xisheng Weng

Published online on: October 17, 2017

Hepatitis C virus p7 induces mitochondrial depolarization of isolated liver mitochondria

Deok‑Gyun You, Hye‑Ra Lee, Won‑Ki Kim, Hyung Jung Kim, Gi Young Lee, Young Do Yoo

Published online on: October 17, 2017

Effects of deferoxamine on the osteogenic differentiation of human periodontal ligament cells

Sen Mu, Shuanlong Guo, Xiang Wang, Yuanbo Zhan, Ying Li, Ying Jiang, Ruimin Zhang, Bin Zhang

Published online on: October 17, 2017

Modulation of mitogen‑activated protein kinase attenuates sepsis‑induced acute lung injury in acute respiratory distress syndrome rats

Wei Fang, Shi‑Xia Cai, Chuan‑Lei Wang, Xiao‑Xia Sun, Kun Li, Xiao‑Wen Yan, Yun‑Bo Sun, Xiao‑Zhe Sun, Chuan‑Kai Gu, Ming‑Ying Dai, Hui‑Ming Wang, Zhen Zhou

Published online on: October 17, 2017

Effect of SOX2 on odontoblast differentiation of dental pulp stem cells

Yali Yang, Yifan Zhao, Xiaobo Liu, Yaoyu Chen, Pengfei Liu, Lei Zhao

Published online on: October 17, 2017
Open Access

Hydrogen sulfide regulates bone remodeling and promotes orthodontic tooth movement

Haiya Pu, Yongmei Hua

Published online on: October 17, 2017

MicroRNA‑760 inhibits cell proliferation and invasion of colorectal cancer by targeting the SP1‑mediated PTEN/AKT signalling pathway

Xiaoyan Li, Yuansheng Ding, Naiqing Liu, Qinli Sun, Jie Zhang

Published online on: October 17, 2017

Autophagy is essential for flavopiridol‑induced cytotoxicity against MCF‑7 breast cancer cells

Shuo Wang, Kai Wang, Huaiquan Wang, Jiankui Han, Hukui Sun

Published online on: October 17, 2017
Open Access

The role of the miR-99b-5p/mTOR signaling pathway in neuroregeneration in mice following spinal cord injury

Fujiang Cao, Tao Liu, Shiwei Sun, Shiqing Feng

Published online on: October 17, 2017
Open Access

Oxidized low density lipoprotein facilitates tumor necrosis factor‑α mediated chondrocyte death via autophagy pathway

Pengcheng Shen, Yu Zhu, Lifan Zhu, Fengbiao Weng, Xiaolin Li, Yaozeng Xu

Published online on: October 13, 2017

Upregulation of Rho7 in the temporal lobe tissue of humans with intractable epilepsy

Xinglong Yang, Baiyuan Yang, Haonan Li, Hui Ren

Published online on: October 13, 2017

3,3'‑Diindolylmethane attenuates cardiomyocyte hypoxia by modulating autophagy in H9c2 cells

Kai Liang, Wen‑Hao Qian, Jing Zong

Published online on: October 13, 2017
Open Access

Caveolin‑1 regulates oxidative stress‑induced senescence in nucleus pulposus cells primarily via the p53/p21 signaling pathway in vitro

Lei Ding, Qingmin Zeng, Jingping Wu, Defang Li, Houlei Wang, Wei Lu, Zengxin Jiang, Guoxiong Xu

Published online on: October 13, 2017

MicroRNA‑455 inhibits cell proliferation and invasion of epithelial ovarian cancer by directly targeting Notch1

Lixia Xu, Haiyan Li, Lei Su, Qian Lu, Zhenfeng Liu

Published online on: October 13, 2017

TRAIL mutant membrane penetrating peptide alike (TMPPA) TRAIL‑Mu3 enhances the antitumor effects of TRAIL in vitro and in vivo

Hong Zhu, Juan Yan, Qi Xu, Lijia Wei, Xianzhou Huang, Shouchun Chen, Cheng Yi

Published online on: October 13, 2017

Vasohibin2 promotes adriamycin resistance of breast cancer cells through regulating ABCG2 via AKT signaling pathway

Deliang Ma, Liang Wu, Shuangjie Li, Zhigang Sun, Kai Wang

Published online on: October 13, 2017

Inhibitory effect of 1‑tetradecanol on Helicobacter pylori‑induced production of interleukin‑8 and vascular endothelial growth factor in gastric epithelial cells

Green Kim, Jae‑Eun Kim, Min‑Jung Kang, Ah‑Ra Jang, Young Ran Kim, Sunoh Kim, Kyu‑Tae Chang, Jung Joo Hong, Jong‑Hwan Park

Published online on: October 13, 2017
Open Access

Hyperthermia with different temperatures inhibits proliferation and promotes apoptosis through the EGFR/STAT3 pathway in C6 rat glioma cells

Yao‑Dong Chen, Yu Zhang, Tian‑Xiu Dong, Yu‑Tong Xu, Wei Zhang, Ting‑Ting An, Peng‑Fei Liu, Xiu‑Hua Yang

Published online on: October 12, 2017

Potential lncRNA diagnostic biomarkers for early gastric cancer

Qin Lu, Ting Yu, Xilong Ou, Dazhong Cao, Ting Xie, Xia Chen

Published online on: October 12, 2017

Sporamin suppresses growth of human esophageal squamous cell carcinoma cells by inhibition of NF‑κB via an AKT‑independent pathway

Cui‑Juan Qian, Yong‑Xiao Qi, Xiao‑Ying Chen, Ju‑Ping Zeng, Jun Yao

Published online on: October 12, 2017

SIRT1 activation by resveratrol reduces brain edema and neuronal apoptosis in an experimental rat subarachnoid hemorrhage model

Cong Qian, Jianxiang Jin, Jingyin Chen, Jianru Li, Xiaobo Yu, Hangbo Mo, Gao Chen

Published online on: October 12, 2017
Open Access

Effect of the adenovirus‑mediated Wip1 gene on lumbar intervertebral disc degeneration in a rabbit model

Yuan Wang, Yong Yang, Jing‑Chuan Sun, Qin‑Jie Kong, Hai‑Bo Wang, Jian‑Gang Shi

Published online on: October 12, 2017

lncRNA ROR promotes the proliferation of renal cancer and is negatively associated with favorable prognosis

Jianguo Shi, Wen Zhang, Hongyang Tian, Qiang Zhang, Tongyi Men

Published online on: October 12, 2017

Concentration‑dependent effects of paeoniflorin on proliferation and apoptosis of vascular smooth muscle cells

Yanan Guo, Yintao Zhao, Ling Li, Xiaoyun Wei, Pingjun Gao, Yanqiang Zhou, Yuan Liu, Haibo Yang

Published online on: October 12, 2017

Isoimperatorin ameliorates osteoarthritis by downregulating the mammalian target of rapamycin C1 signaling pathway

Jiayao Ouyang, Huaji Jiang, Hang Fang, Wenbo Cui, Daozhang Cai

Published online on: October 12, 2017
Open Access

Calcitonin gene‑related peptide induces IL‑6 expression in RAW264.7 macrophages mediated by mmu_circRNA_007893

Tian Deng, Lan Yang, Zhichao Zheng, Yuanjing Li, Wen Ren, Caijuan Wu, Lvhua Guo

Published online on: October 12, 2017
Open Access

Frequency and distribution of CD4+CXCR5+ follicular B helper T cells within involved tissues in IgG4‑related ophthalmic disease

Huimin Yang, Ruili Wei, Qiang Liu, Yongheng Shi, Jin Li

Published online on: October 12, 2017

Synthesis of regioselectively acylated quercetin analogues with improved antiplatelet activity

Yu Duan, Na Sun, Min Xue, Xiaolan Wang, Hu Yang

Published online on: October 12, 2017

Adipose‑derived mesenchymal stem cells attenuate cisplatin‑induced apoptosis in epithelial ovarian cancer cells

Yiping Wen, Yan Guo, Zaiju Huang, Jing Cai, Zehua Wang

Published online on: October 12, 2017
Open Access

Combination of oncolytic adenovirus and luteolin exerts synergistic antitumor effects in colorectal cancer cells and a mouse model

Boduan Xiao, Yun Qin, Chang Ying, Buyun Ma, Binrong Wang, Fei Long, Ruwei Wang, Ling Fang, Yigang Wang

Published online on: October 12, 2017
Open Access

Adenoviral‑bone morphogenetic protein‑7 and/or doxazosin therapies promote the reversion of fibrosis/cirrhosis in a cirrhotic hamster model

Daniel Cervantes‑Garcia, Adriana Guadalupe Cuellar‑Juarez, Gissela Borrego‑Soto, Augusto Rojas‑Martinez, Liseth Rubi Aldaba‑Muruato, Eva Salinas, Javier Ventura‑Juarez, Martin Humberto Muñoz‑Ortega

Published online on: October 12, 2017
Open Access

An investigation of methyl tert‑butyl ether‑induced cytotoxicity and protein profile in Chinese hamster ovary cells

Guangshan Xie, Wen‑Xu Hong, Li Zhou, Xifei Yang, Haiyan Huang, Desheng Wu, Xinfeng Huang, Weiguo Zhu, Jianjun Liu

Published online on: October 11, 2017
Open Access

Prognostic implications and procoagulant activity of phosphatidylserine exposure of blood cells and microparticles in patients with atrial fibrillation treated with pulmonary vein isolation

Huan Meng, Junjie Kou, Ruishuang Ma, Wenbo Ding, Yan Kou, Muhua Cao, Zengxiang Dong, Yayan Bi, Hemant S. Thatte, Jialan Shi

Published online on: October 11, 2017

Inhibitory effects of ubiquitination of synoviolin by PADI4

Satoko Aratani, Hidetoshi Fujita, Naoko Yagishita, Yoshihisa Yamano, Yukari Okubo, Kusuki Nishioka, Toshihiro Nakajima

Published online on: October 11, 2017

Propofol regulates the expression of TLR4 through miR‑21 in human umbilical vein endothelial cells

Ling Ma, Yue Yang, Xuechen Sun, Meiling Jiang, Yang Ma, Xilun Yang, Zhiwei Guo

Published online on: October 11, 2017

Co‑expression of murine double minute 2 siRNA and wild‑type p53 induces G1 cell cycle arrest in H1299 cells

Long Liu, Ping Zhang, Hua Guo, Xinyu Tang, Lianqin Liu, Jiuling Li, Rui Guo, Yangyang Cai, Yanan Liu, Yang Li

Published online on: October 11, 2017

Inhibitory effects of lupane‑type triterpenoid saponins from the leaves of Acanthopanax gracilistylus on lipopolysaccharide-induced TNF‑α, IL‑1β and high‑mobility group box 1 release in macrophages

Qin‑Peng Zou, Xiang‑Qian Liu, Jian‑Jun Huang, Chang‑Soo Yook, Wan‑Kyunn Whang, Hyeong‑Kyu Lee, Ok‑Kyoung Kwon

Published online on: October 11, 2017
Open Access

Serum metabolomic profile in genetically modified cows carrying human α‑lactalbumin gene

Qin Wang, Wei Fu, Xiaofei Liu, Jianwu Wang, Chunyan Feng, Songyin Qiu, Xiaolin Li, Dandan Liu, Shuifang Zhu, Xiangmei Lin

Published online on: October 11, 2017
Open Access

Staphylococcus aureus colonisation in patients from a primary regional hospital

Anca Ungureanu, Ovidiu Zlatian, George Mitroi, Andrei Drocaş, Tiberiu Ţîrcă, Daniela Călina, Cristina Dehelean, Anca Oana Docea, Boris N. Izotov, Valerii N. Rakitskii, Ramona Cioboată, Demetrios A. Spandidos, Aristides M. Tsatsakis, Alice Găman

Published online on: October 10, 2017

IL‑8 promotes proliferation and inhibition of apoptosis via STAT3/AKT/NF‑κB pathway in prostate cancer

Yidi Guo, Ying Zang, Lianzheng Lv, Feng Cai, Tingting Qian, Guoying Zhang, Quancheng Feng

Published online on: October 10, 2017

Baicalin alleviates H2O2‑induced injury of H9c2 cardiomyocytes through suppression of the Wnt/β‑catenin signaling pathway

Liman Qiu, Jinxiao Chen, Jing Lin, Da Wo, Jianfeng Chu, Jun Peng

Published online on: October 10, 2017

Analysis of MEN1 c.482G>A (p.Gly161Asp) mutation in a pedigree with familial multiple endocrine neoplasia type 1

Yuanyuan Luo, Yongxiang Sun, Xiaofan Zhu, Xialian Li

Published online on: October 10, 2017
Open Access

BIRC5 is a novel target of peroxisome proliferator‑activated receptor γ in brain microvascular endothelium cells during cerebral ischemia

Mingjing Xu, Xianli Yang, Qing Zeng, He He, Pengcheng Lu, Guozhi Huang

Published online on: October 10, 2017

Characterization of acid‑tolerance‑associated small RNAs in clinical isolates of Streptococcus mutans: Potential biomarkers for caries prevention

Wenhui Zhu, Shanshan Liu, Peilin Zhuang, Jia Liu, Yan Wang, Huancai Lin

Published online on: October 10, 2017

Insulin in combination with cisplatin induces the apoptosis of ovarian cancer cells via p53 and JNK activation

Ting Zhao, Jun Bai, Qingyun Zou, Feng Chen, Yan Xie

Published online on: October 10, 2017

Homocysteine‑induced oxidative stress through TLR4/NF‑κB/DNMT1‑mediated LOX‑1 DNA methylation in endothelial cells

Sheng‑Chao Ma, Yin‑Ju Hao, Yun Jiao, Yan‑Hua Wang, Ling‑Bo Xu, Cai‑Yan Mao, Xiao‑Ling Yang, An‑Ning Yang, Jue Tian, Ming‑Hao Zhang, Shao‑Ju Jin, Hua Xu, Yi‑Deng Jiang, Hui‑Ping Zhang

Published online on: October 10, 2017
Open Access

Evaluation of a novel dry eye model induced by oral administration of finasteride

Kai Li, Chuanwei Zhang, Zichao Yang, Yuliang Wang, Haipeng Si

Published online on: October 10, 2017

Leflunomide inhibits proliferation and tumorigenesis of oral squamous cell carcinoma

Aishu Ren, Gang Fu, Yu Qiu, Hongjuan Cui

Published online on: October 10, 2017
Open Access

Antitumor effects of baicalin on ovarian cancer cells through induction of cell apoptosis and inhibition of cell migration in vitro

Chen Gao, Yinglu Zhou, Huatao Li, Xia Cong, Zhongling Jiang, Xin Wang, Rongfeng Cao, Wenru Tian

Published online on: October 10, 2017

miR‑203 contributes to IL‑17‑induced VEGF secretion by targeting SOCS3 in keratinocytes

Yuanyuan Xu, Yongzhi Ji, Xiaoou Lan, Xinghua Gao, Hong‑Duo Chen, Long Geng

Published online on: October 10, 2017
Open Access

Partial monosomy 8p and trisomy 16q in two children with developmental delay detected by array comparative genomic hybridization

Zoe Papadopoulou, Ioannis Papoulidis, Stavros Sifakis, Georgios Markopoulos, Annalisa Vetro, Angeliki‑Maria Vlaikou, Monica Ziegler, Thomas Liehr, Loretta Thomaidis, Orsetta Zuffardi, Maria Syrrou, Kitsos George, Emmanouil Manolakos

Published online on: October 10, 2017
Open Access

Calcium dobesilate may alleviate diabetes‑induced endothelial dysfunction and inflammation

Yijun Zhou, Jiangzi Yuan, Chaojun Qi, Xinghua Shao, Shan Mou, Zhaohui Ni

Published online on: October 9, 2017
Open Access

Gene expression profile identifies potential biomarkers for human intervertebral disc degeneration

Wei Guo, Bin Zhang, Yan Li, Hui‑Quan Duan, Chao Sun, Yun‑Qiang Xu, Shi‑Qing Feng

Published online on: October 9, 2017

Dihydromyricetin protects against lipopolysaccharide‑induced cardiomyocyte injury through the toll‑like receptor‑4/nuclear factor‑κB pathway

Meng‑Qiao Zhou, Ling Shao, Jing Wu, Na Peng, Lu‑Ping Jin, Guo‑Zhen Wei, Wei Cheng, Chang‑Jin Deng

Published online on: October 9, 2017

Tanshinone IIA inhibits high glucose‑induced proliferation, migration and vascularization of human retinal endothelial cells

Keshun Fan, Suyan Li, Gaoqin Liu, Honghua Yuan, Li Ma, Peirong Lu

Published online on: October 9, 2017
Open Access

ID1 contributes to cell growth invasion and migration in salivary adenoid cystic carcinoma

Xiao‑Meng Hu, Ting Lin, Xiao‑Yu Huang, Rui‑Huan Gan, Yong Zhao, Yan Feng, Lin‑Can Ding, Bo‑Hua Su, Da‑Li Zheng, You‑Guang Lu

Published online on: October 9, 2017

The FNR modules contribute to control nitric oxide synthase catalysis revealed by chimera enzymes

Ruiqiang Wang, Biyue Wang, Bowen Zheng, Pupu Ma, Rong Gou, Yuanyuan Guo, Fengmei Chen, Hua Li, Yi Wang, Juanjuan Pu, Lin Tang

Published online on: October 9, 2017
Open Access

Administration of erythropoietin prevents bone loss in osteonecrosis of the femoral head in mice

Taotao Xu, Hongting Jin, Yangjun Lao, Pinger Wang, Shanxing Zhang, Hongfeng Ruan, Qiang Mao, Li Zhou, Luwei Xiao, Peijian Tong, Chengliang Wu

Published online on: October 6, 2017
Open Access

Matrine in association with FD‑2 stimulates F508del‑cystic fibrosis transmembrane conductance regulator activity in the presence of corrector VX809

Barbara Marengo, Andrea Speciale, Lisa Senatore, Silvano Garibaldi, Francesca Musumeci, Erika Nieddu, Benedetta Pollarolo, Maria Adelaide Pronzato, Silvia Schenone, Mauro Mazzei, Cinzia Domenicotti

Published online on: October 6, 2017
Open Access

Effects of ginsenoside‑Rg1 on the proliferation and glial‑like directed differentiation of embryonic rat cortical neural stem cells in vitro

Jian Gao, Feng Wan, Mo Tian, Yuanyuan Li, Yuxuan Li, Qiang Li, Jianping Zhang, Yongxue Wang, Xiang Huang, Lijuan Zhang, Yinchu Si

Published online on: October 6, 2017
Open Access

Role of artesunate in TGF‑β1‑induced renal tubular epithelial‑mesenchymal transdifferentiation in NRK‑52E cells

Yaqian Zhang, Huanhuan Li, Jiajun Zhu, Tiantian Wei, Yingxian Peng, Ran Li, Rui Xu, Mei Li, Anzhou Xia

Published online on: October 5, 2017

Impact of biopersistent fibrous dusts on glycolysis, glutaminolysis and serine metabolism in A549 cells

Sybille Wache, Simone Helmig, Dirk Walter, Joachim Schneider, Sybille Mazurek

Published online on: October 5, 2017
Open Access

Antiangiogenic properties of caudatin in vitro and in vivo by suppression of VEGF‑VEGFR2‑AKT/FAK signal axis

Xinzhi Wang, Xiaoting Fu, Shijun Zhao, Xiaoyan Fu, Huifang Zhang, Lurong Shao, Gang Li, Cundong Fan

Published online on: October 5, 2017
Open Access

miR‑342‑5p promotes Zmpste24‑deficient mouse embryonic fibroblasts proliferation by suppressing GAS2

Chun‑Long Zhang, Xinguang Liu, Qiu‑Jing He, Huiling Zheng, Shun Xu, Xing‑Dong Xiong, Yuan Yuan, Jie Ruan, Jiang‑Bin Li, Yu Xing, Zhongjun Zhou, Shixiong Deng

Published online on: October 5, 2017

MicroRNA‑720 inhibits pancreatic cancer cell proliferation and invasion by directly targeting cyclin D1

Yu Zhang, Yueying Su, Yabing Zhao, Guoqiang Lv, Ying Luo

Published online on: October 5, 2017
Open Access

Τhe genetics of juvenile idiopathic arthritis: Searching for new susceptibility loci

Maria I. Zervou, Despoina G. Dimopoulou, Elias Eliopoulos, Maria Trachana, Polyxeni Pratsidou‑Gkertsi, Athena Andreou, Prodromos Sidiropoulos, Demetrios A. Spandidos, Alexandros Garyfallos, George N. Goulielmos

Published online on: October 5, 2017

Leber's hereditary optic neuropathy is potentially associated with a novel m.5587T>C mutation in two pedigrees

Yanchun Ji, Lihua Qiao, Xiaoyang Liang, Ling Zhu, Yinglong Gao, Juanjuan  Zhang, Zidong Jia, Qi‑Ping Wei, Xiaoling Liu, Pingping Jiang, Min‑Xin Guan

Published online on: October 5, 2017

Silver nanoparticles coupled to anti‑EGFR antibodies sensitize nasopharyngeal carcinoma cells to irradiation

Dahai Yu, Yan Zhang, Hong Lu, Di Zhao

Published online on: October 4, 2017

MicroRNA‑24‑2 is associated with cell proliferation, invasion, migration and apoptosis in renal cell carcinoma

Lu Jin, Yifan Li, Liping Nie, Tao He, Jia Hu, Jiaju Liu, Mingwei Chen, Min Shi, Zhimao Jiang, Yaoting Gui, Shangqi Yang, Yongqing Lai

Published online on: October 4, 2017
Open Access

Imperatorin possesses notable anti‑inflammatory activity in vitro and in vivo through inhibition of the NF‑κB pathway

Xiaoxia Zhang, Wenchao Li, Aikebaier Abudureheman, Tao Cheng, Peng Peng

Published online on: October 4, 2017
Open Access

Metformin accelerates wound healing in type 2 diabetic db/db mice

Xue Han, Yulong Tao, Yaping Deng, Jiawen Yu, Yuannan Sun, Guojun Jiang

Published online on: October 4, 2017
Open Access

WWC1 promotes podocyte survival via stabilizing slit diaphragm protein dendrin

Ting Lin, Li Zhang, Shuangxin Liu, Yuanhan Chen, Hong Zhang, Xingchen Zhao, Ruizhao Li, Qianmei Zhang, Ruyi Liao, Zongshun Huang, Bin Zhang, Wenjian Wang, Xinling Liang, Wei Shi

Published online on: October 4, 2017
Open Access

miR‑494 inhibits cell proliferation and metastasis via targeting of CDK6 in osteosarcoma

Wei Yuan, Du Wang, Yang Liu, Dongdong Tian, Yang Wang, Ranxi Zhang, Liangjun Yin, Zhongliang Deng

Published online on: October 4, 2017

Ginsenoside Rb1 inhibits free fatty acids‑induced oxidative stress and inflammation in 3T3‑L1 adipocytes

Min Wang, Yanming Chen, Zhaojun Xiong, Shujie Yu, Bin Zhou, Yesheng Ling, Zhenda Zheng, Guangyao Shi, Yongxiang Wu, Xiaoxian Qian

Published online on: October 4, 2017
Open Access

Integrated microarray analysis provided novel insights to the pathogenesis of glaucoma

Jinhui Wang, Daofei Qu, Jinghong An, Guoming Yuan, Yufu Liu

Published online on: October 4, 2017

Thevetiaflavone from Wikstroemia indica ameliorates PC12 cells injury induced by OGD/R via improving ROS‑mediated mitochondrial dysfunction

Huankai Yao, Zhenhai Yuan, Guangming Wei, Chun Chen, Jingyu Duan, Yan Li, Yunru Wang, Chunping Zhang, Yuanhua Liu

Published online on: October 4, 2017
Open Access

Effect of miR‑146a‑5p on tumor growth in NSCLC using chick chorioallantoic membrane assay and bioinformatics investigation

Wen‑Ting Huang, Wei‑Luan Cen, Rong‑Quan He, You Xie, Yu Zhang, Ping Li, Ting‑Qing Gan, Gang Chen, Xiao‑Hua Hu

Published online on: October 4, 2017
Open Access

Gaseous signalling molecule SO2 via Hippo‑MST pathway to improve myocardial fibrosis of diabetic rats

Maojun Liu, Shengquan Liu, Wenting Tan, Fen Tang, Junrong Long, Zining Li, Biao Liang, Chun Chu, Jun Yang

Published online on: October 4, 2017

SiRNA directed against NF‑κB inhibits mononuclear macrophage cells releasing proinflammatory cytokines in vitro

Chunting Wu, Jiahui Zhao, Guangfa Zhu, Yan Huang, Liyan Jin

Published online on: October 4, 2017

Kangfuxin promotes apoptosis of gastric cancer cells through activating ER‑stress and autophagy

Pian‑Pian Chen, Xiu‑Ying Ma, Qian Lin, He‑Lin Xu, Hong‑Xue Shi, Hong‑Yu Zhang, Jian Xiao, Fu‑Neng Geng, Ying‑Zheng Zhao

Published online on: October 4, 2017

Confirmation and preliminary analysis of circRNAs potentially involved in human intervertebral disc degeneration

Fei Zou, Zhiwen Ding, Jianyuan Jiang, Feizhou Lu, Xinlei Xia, Xiaosheng Ma

Published online on: October 4, 2017

Fluid shear stress induces osteoblast differentiation and arrests the cell cycle at the G0 phase via the ERK1/2 pathway

Liyin Yu, Xingfeng Ma, Junqin Sun, Jie Tong, Liang Shi, Lijun Sun, Jianbao Zhang

Published online on: October 4, 2017
Open Access

MACC1 facilitates chemoresistance and cancer stem cell‑like properties of colon cancer cells through the PI3K/AKT signaling pathway

Jiankai Wang, Wenjuan Wang, Hongyi Cai, Binbin Du, Lijuan Zhang, Wen Ma, Yongguo Hu, Shifang Feng, Guoying Miao

Published online on: October 4, 2017
Open Access

MicroRNA expression profiling of intestinal mucosa tissue predicts multiple crucial regulatory molecules and signaling pathways for gut barrier dysfunction of AIDS patients

Yu Xu, Hua‑Wei Wang, Hua‑You Luo, Ruo Shu, Jia Liu, Liang Sun, Xue‑Fei Han, Na Lin, Ting‑Hua Wang, Yu‑Jian Zeng, Kun‑Hua Wang

Published online on: October 4, 2017

Downregulation of SYT7 inhibits glioblastoma growth by promoting cellular apoptosis

Bing Xiao, Jianbin Li, Yanghua Fan, Minhua Ye, Shigang Lv, Bin Xu, Yi Chai, Zhiqing Zhou, Miaojing Wu, Xingen Zhu

Published online on: October 4, 2017

ID3 may protect mice from anti‑GBM glomerulonephritis by regulating the differentiation of Th17 and Treg cells

Huan Zhou, Le Wang, Qing Xu, Qingquan Liu, Hui Liu, Wenhui Qiu, Tingyang Hu, Yongman Lv, Qian Zhang

Published online on: October 4, 2017
Open Access

Neuroprotective effect of chondroitin sulfate on SH‑SY5Y cells overexpressing wild‑type or A53T mutant α‑synuclein

Chuanxia Ju, Jianjun Gao, Lin Hou, Lei Wang, Fang Zhang, Fusheng Sun, Tingting Zhang, Pingping Xu, Zhenyan Shi, Fang Hu, Congxiao Zhang

Published online on: October 4, 2017
Open Access

Identification and bioinformatics analysis of miRNAs associated with human muscle invasive bladder cancer

Liang Chen, Lushun Yuan, Gang Wang, Rui Cao, Jianping Peng, Bo Shu, Guofeng Qian, Xinghuan Wang, Yu Xiao

Published online on: October 4, 2017

SNPs of CD14 change the mastitis morbidity of Chinese Holstein

Jun Li, Qiang Wang, Fanghui Chen, Haosen Wang, Jie Chen, Zhao Wang, Jiayan Huo, Yafei Cai

Published online on: October 4, 2017
Open Access

Mechanism of the effect of saikosaponin on atherosclerosis in vitro is based on the MAPK signaling pathway

Lin Yang, Jianlin Liu, Guangyu Qi

Published online on: October 3, 2017
Open Access

Rapamycin promotes osteogenesis under inflammatory conditions

Xing Li, Bei Chang, Banchao Wang, Wenhuan Bu, Liang Zhao, Jie Liu, Lin Meng, Lu Wang, Ying Xin, Dandan Wang, Qi Tang, Changyu Zheng, Hongchen Sun

Published online on: October 3, 2017
Open Access

Kinin B1 receptor as a novel, prognostic progression biomarker for carotid atherosclerotic plaques

Tiantian Liu, Hengfang Liu, Li Feng, Bo Xiao

Published online on: October 3, 2017

Anti‑inflammatory effect of Amomum xanthioides in a mouse atopic dermatitis model

Young‑Ae Choi, Jin Kyeong Choi, Yong Hyun Jang, Soyoung Lee, Sang‑Rae Lee, Jung Ho Choi, Jee Hun Park, Tae‑Yong Shin, Sang‑Hyun Kim

Published online on: October 3, 2017
Open Access

Low molecular weight heparin may benefit nephrotic remission in steroid‑sensitive nephrotic syndrome via inhibiting elastase

Songhui Zhai, Lijuan Hu, Lin Zhong, Yuhong Tao, Zheng Wang

Published online on: October 3, 2017
Open Access

[Corrigendum] Farnesoid X receptor deletion improves cardiac function, structure and remodeling following myocardial infarction in mice

Jianshu Gao, Xiaoqiang Liu, Bingjian Wang, Haiyan Xu, Qiang Xia, Tianfei Lu, Fang Wang

Published online on: October 3, 2017
Open Access

Estradiol‑enhanced osteogenesis of rat bone marrow stromal cells is associated with the JNK pathway

Nan Song, Zhi‑Min Wang, Li‑Juan He, Yan Xu, Yan‑Ling Ren

Published online on: October 3, 2017

Effects of butylphthalide on cognitive decline in diabetic rats

Zhiyan Tian, Jinhua Wang, Yan Wang, Miao Zhang, Yuying Zhou

Published online on: October 3, 2017

Puerarin inhibits β‑amyloid peptide 1‑42‑induced tau hyperphosphorylation via the Wnt/β‑catenin signaling pathway

Ying Yao, Xianchun Chen, Yuting Bao, Yangsheng Wu

Published online on: October 3, 2017

Identifying dysregulated pathways in postmenopausal osteoporosis through investigation of crosstalk between pathways

Jian-Hua Han, Xiao-Jun Cai, Hou-Jie Sun, Ge-Hui Dong, Bin He, Han-Xiang Zhang, Xin Zhou, Jia-Qiang Yan

Published online on: October 3, 2017

Arctiin regulates collagen type 1α chain 1 mRNA expression in human dermal fibroblasts via the miR‑378b‑SIRT6 axis

Karam Kim, Sungkwan An, Byung Gon Choi, Dahye Joo, Young Min Choi, Kyu Joong Ahn, In‑Sook An, Hwa Jun Cha

Published online on: October 2, 2017
Open Access

2,3,5,4‑tetrahydroxy diphenylethylene‑2‑O‑glucoside inhibits the adhesion and invasion of A549 human lung cancer cells

Ming Xu, Cong Wang, Minglin Zhu, Xianguo Wang, Li Zhang, Jinping Zhao

Published online on: October 2, 2017

Increased expression of high mobility group box protein 1 and vascular endothelial growth factor in placenta previa

Han Xie, Ping Qiao, Yi Lu, Ying Li, Yuping Tang, Yiying Huang, Yirong Bao, Hao Ying

Published online on: October 2, 2017
Open Access

Elevated expression of SATB1 is involved in pancreatic tumorigenesis and is associated with poor patient survival

Lei Guo, Jianjiang Zheng, Tao Yu, Yuequan Liu, Lukun Duo

Published online on: October 2, 2017
Open Access

Macrophage migration inhibitory factor knockdown inhibit viability and induce apoptosis of PVM/Ms

Wenjing Zhang, Jian Zheng, Juan Meng, Lingling Neng, Xiaohua Chen, Zhaobing Qin

Published online on: October 2, 2017

Inhibitory effect of the anthelmintic drug pyrvinium pamoate on T315I BCR‑ABL‑positive CML cells

Jing Zhang, Yanli Jin, Jingxuan Pan

Published online on: October 2, 2017

Chlorogenic acid suppresses lipopolysaccharide‑induced nitric oxide and interleukin‑1β expression by inhibiting JAK2/STAT3 activation in RAW264.7 cells

Sang‑Hun Kim, Sun‑Young Park, Young‑Lan Park, Dae‑Seong Myung, Jong‑Sun Rew, Young‑Eun Joo

Published online on: October 2, 2017
Open Access

Global transcriptome‑wide analysis of the function of GDDR in acute gastric lesions

Ziqiang Zhang, Jie Zhu, Yuanqiang Dong, Hongyuan Xu, Tao Jiang, Wenshuai Li, Diannan Xu, Liubin Shi, Jianghong Yu, Jun Zhang, Jianjun Du

Published online on: October 2, 2017

Diagnostic and prognostic value of serum interleukin‑16 in patients with gastric cancer

Hongyun Yang, Yanyan Han, Lele Wu, Chaojun Wu

Published online on: October 2, 2017
Open Access

P38/ERK MAPK signaling pathways are involved in the regulation of filaggrin and involucrin by IL‑17

Qi Tan, Huan Yang, Enmei Liu, Hua Wang

Published online on: October 2, 2017

A novel compound heterozygous mutation of SLC26A4 in two Chinese families with nonsyndromic hearing loss and enlarged vestibular aqueducts

Guang‑Jie Zhu, Lu‑Sen Shi, Han Zhou, Ye Yang, Jie Chen, Xia Gao

Published online on: October 2, 2017

NOD receptor and TLR9 modulation in severe acute pancreatitis‑induced intestinal injury

Yupeng Yan, Bin Lu, Pengyang Li, Ji Wang

Published online on: September 29, 2017

RhoA regulates lipopolysaccharide‑induced lung cell injury via the Wnt/β‑catenin pathway

Guanhua Chen, Xuedong Sun, Chunxiao Dong

Published online on: September 29, 2017

High incidence of coding gene mutations in mitochondrial DNA in esophageal cancer

Zong‑Wen Liu, Zhen‑Jiang Guo, A‑Lan Chu, Yan Zhang, Bing Liang, Xing Guo, Ting Chai, Rui Song, Ge Hou, Jin‑Jin Yuan

Published online on: September 29, 2017

MicroRNA‑320 targets mitogen‑activated protein kinase 1 to inhibit cell proliferation and invasion in epithelial ovarian cancer

Yongqian Xu, Jian Hu, Chunxia Zhang, Yuanyuan Liu

Published online on: September 29, 2017

Fructose‑1,6‑bisphosphatase‑1 decrease may promote carcinogenesis and chemoresistance in cervical cancer

Haoran Li, Mengjiao Li, Yangyang Pang, Fei Liu, Dong Sheng, Xi Cheng

Published online on: September 29, 2017
Open Access

Identification of key genes for diabetic kidney disease using biological informatics methods

Fuzhe Ma, Tao Sun, Meiyan Wu, Wanning Wang, Zhonggao Xu

Published online on: September 29, 2017
Open Access

The effect of anagliptin on intimal hyperplasia of rat carotid artery after balloon injury

Qi Li, Xiayang Wu, Yanli Liu, Mingyu Zhang, Xue Bai, Chang Chen

Published online on: September 29, 2017
Open Access

Brain iron deposition analysis using susceptibility weighted imaging and its association with body iron level in patients with mild cognitive impairment

Lili Gao, Zhihong Jiang, Zhaocheng Cai, Ming Cai, Qing Zhang, Yingying Ma, Guoliang Li, Fengzhu Zhao, Qiang Ma

Published online on: September 29, 2017
Open Access

Knockdown of Indian hedgehog protein induces an inhibition of cell growth and differentiation in osteoblast MC3T3‑E1 cells

Ang Deng, Hongqi Zhang, Minyu Hu, Shaohua Liu, Qile Gao, Yuxiang Wang, Chaofeng Guo

Published online on: September 29, 2017

Calcineurin/NFAT signaling pathway mediates titanium particle‑induced inflammation and osteoclast formation by inhibiting RANKL and M‑CSF in vitro

Yunge Zhang, Peng Jiang, Wenbo Li, Xiangjie Liu, Yang Lu, Zhipeng Huang, Keguan Song

Published online on: September 29, 2017
Open Access

Genome‑wide analysis and prediction of functional long noncoding RNAs in osteoblast differentiation under simulated microgravity

Zebing Hu, Han Wang, Yixuan Wang, Hua Zhou, Fei Shi, Jiangdong Zhao, Shu Zhang, Xinsheng Cao

Published online on: September 29, 2017
Open Access

Exogenous peripheral blood mononuclear cells affect the healing process of deep‑degree burns

Guanying Yu, Yaonan Li, Lan Ye, Xinglei Wang, Jixun Zhang, Zhengxue Dong, Duyin Jiang

Published online on: September 29, 2017

Dietary n‑3 polyunsaturated fatty acids ameliorate Crohn's disease in rats by modulating the expression of PPAR‑γ/NFAT

Jiayin Yao, Yi Lu, Min Zhi, Pinjin Hu, Wei Wu, Xiang Gao

Published online on: September 29, 2017

Expression of NR1 and apoptosis levels in the hippocampal cells of mice treated with MK‑801

Juan Ding, Hui‑Hui Zhou, Quan‑Rui Ma, Zhong‑Yi He, Jiang‑Bo Ma, Yin‑Ming Liu, Yi‑Wei Zhang, Yu‑Qing He, Juan Liu

Published online on: September 29, 2017
Open Access

miR‑647 and miR‑1914 promote cancer progression equivalently by downregulating nuclear factor IX in colorectal cancer

Shaoqing Liu, Dingding Qu, Weiping Li, Chenxiang He, Shisen Li, Guosheng Wu, Qingchuan Zhao, Liangliang Shen, Jian Zhang, Jianyong Zheng

Published online on: September 29, 2017

Inhibition of cardiotrophin‑1 overexpression is involved in the anti‑fibrotic effect of Astrogaloside IV

Guizhi Jia, Bin Leng, Hongxin Wang, Hongliang Dai

Published online on: September 29, 2017

miRNA‑34a‑5p downregulation of VEGFA in endometrial stem cells contributes to the pathogenesis of endometriosis

Ying Ma, Yu‑Xin Huang, Yan‑Ying Chen

Published online on: September 29, 2017
Open Access

Defective insulin signaling and the protective effects of dimethyldiguanide during follicular development in the ovaries of polycystic ovary syndrome

Fan Wang, Shaobing Wang, Zhenghong Zhang, Qingqiang Lin, Yiping Liu, Yijun Xiao, Kaizhuan Xiao, Zhengchao Wang

Published online on: September 29, 2017

Rebamipide upregulates mucin secretion of intestinal goblet cells via Akt phosphorylation

Yuriko Yasuda‑Onozawa, Osamu Handa, Yuji Naito, Chihiro Ushiroda, Yosuke Suyama, Yuki Toyokawa, Takaaki Murakami, Tomoyo Yasuda, Tomohiro Ueda, Atsushi Majima, Yuma Hotta, Toshifumi Doi, Makoto Tanaka, Yusuke Horii, Yasuki Higashimura, Katsura Mizushima, Mayuko Morita, Yukiko Uehara, Hideki Horie, Akifumi Fukui, Osamu Dohi, Tetsuya Okayama, Naohisa Yoshida, Kazuhiro Kamada, Kazuhiro Katada, Kazuhiko Uchiyama, Takeshi Ishikawa, Tomohisa Takagi, Hideyuki Konishi, Yoshito Itoh

Published online on: September 28, 2017
Open Access

Iguratimod prevents ovariectomy‑induced bone loss and suppresses osteoclastogenesis via inhibition of peroxisome proliferator‑activated receptor‑γ

Ying‑Xing Wu, Yue Sun, Ya‑Ping Ye, Peng Zhang, Jia‑Chao Guo, Jun‑Ming Huang, Xing‑Zhi Jing, Wei Xiang, Shi‑Ying Yu, Feng‑Jing Guo

Published online on: September 28, 2017
Open Access

Systematic module approach identifies altered genes and pathways in four types of ovarian cancer

Jing Liu, Hui‑Ling Wang, Feng‑Mei Ma, Hong‑Ping Guo, Ning‑Ning Fang, Shan‑Shan Wang, Xin‑Hong Li

Published online on: September 28, 2017
Open Access

[Retracted] Atorvastatin protects cardiomyocytes against OGD/R‑induced apoptosis by inhibiting miR‑199a‑5p

Yong Li, Ting Jiang, Xingli Fu, Hao Xu, Jianguo Ji

Published online on: September 28, 2017
Open Access

Bufalin induced apoptosis in SCC‑4 human tongue cancer cells by decreasing Bcl‑2 and increasing Bax expression via the mitochondria‑dependent pathway

Han‑Yu Chou, Fu‑Shin Chueh, Yi‑Shih Ma, Rick Sai‑Chuen Wu, Ching‑Lung Liao, Yung‑Lin Chu, Ming‑Jen Fan, Wen‑Wen Huang, Jing‑Gung Chung

Published online on: September 28, 2017
Open Access

Directed transdifferentiation of Müller glial cells to photoreceptors using the sonic hedgehog signaling pathway agonist purmorphamine

Dandan Gu, Songtao Wang, Shuai Zhang, Peng Zhang, Guomin Zhou

Published online on: September 28, 2017
Open Access

Interaction network of coexpressed mRNA, miRNA, and lncRNA activated by TGF‑β1 regulates EMT in human pulmonary epithelial cell

Huizhu Liu, Xueying Zhao, Jing Xiang, Jie Zhang, Chao Meng, Jinjin Zhang, Minge Li, Xiaodong Song, Changjun Lv

Published online on: September 28, 2017

CREB1 and Smad3 mediate TGF‑β3‑induced Smad7 expression in rat hepatic stellate cells

Liang Deng, Lu Huang, Qiongya Guo, Xiaoyu Shi, Keshu Xu

Published online on: September 28, 2017

Dipterocarpus obtusifolius attenuates the effects of lipopolysaccharide‑induced inflammatory response in RAW264.7 macrophages

Ji‑Won Park, Ok‑Kyoung Kwon, Sei‑Ryang Oh, Joongku Lee, Sangmi Eum, Samnang Nguon, Sang Ho Choi, Piseth Khiev, Kyung‑Seop Ahn

Published online on: September 28, 2017

Integrated analysis reveals candidate genes and transcription factors in lung adenocarcinoma

Baiwang Chen, Shuhong Gao, Changwei Ji, Ge Song

Published online on: September 28, 2017

MicroRNA‑378b regulates α‑1‑type 1 collagen expression via sirtuin 6 interference

Dahye Joo, Sungkwan An, Byung Gon Choi, Karam Kim, Young Min Choi, Kyu Joong Ahn, In‑Sook An, Hwa Jun Cha

Published online on: September 28, 2017

Abnormal expression levels of BMP15/Smad1 are associated with granulosa cell apoptosis in patients with polycystic ovary syndrome

Xiangrong Cui, Xuan Jing, Xueqing Wu, Xingyu Bi, Junfen Liu, Zhijing Long, Xiuping Zhang, Dongdong Zhang, Hongxiang Jia, Dan Su, Kai Huo

Published online on: September 28, 2017

Novel insights into the effect of paroxetine administration in pilocarpine‑induced chronic epileptic rats

Wan‑Hui Lin, Xiao‑Feng Li, Ming‑Xing Lin, Ying Zhou, Hua‑Pin Huang

Published online on: September 28, 2017
Open Access

Bmi‑1‑targeting suppresses osteosarcoma aggressiveness through the NF‑κB signaling pathway

Jiaguo Liu, Bin Luo, Meng Zhao

Published online on: September 28, 2017

LDHA promotes tumor metastasis by facilitating epithelial‑mesenchymal transition in renal cell carcinoma

Juping Zhao, Xin Huang, Zhaoping Xu, Jun Dai, Hongchao He, Yu Zhu, Haofei Wang

Published online on: September 27, 2017
Open Access

Circular RNA expression profiles of peripheral blood mononuclear cells in rheumatoid arthritis patients, based on microarray chip technology

Fengping Zheng, Xiangqi Yu, Jiahuang Huang, Yong Dai

Published online on: September 27, 2017

Suppression by HSP90 inhibitors of BMP‑4‑stimulated osteoprotegerin synthesis in osteoblasts: Attenuation of p70 S6 kinase

Tetsu Kawabata, Takanobu Otsuka, Kazuhiko Fujita, Shingo Kainuma, Naohiro Yamamoto, Gen Kuroyanagi, Go Sakai, Rie Matsushima‑Nishiwaki, Osamu Kozawa, Haruhiko Tokuda

Published online on: September 27, 2017
Open Access

Simvastatin attenuated rat thoracic aorta remodeling by decreasing ROCK2‑mediated CyPA secretion and CD147‑ERK1/2‑cyclin pathway

Fu‑Cai Tang, Hong‑Yan Wang, Ming‑Ming Ma, Tian‑Wang Guan, Long Pan, Dun‑Chen Yao, Ya‑Lan Chen, Sheng‑Jie Li, Hang Yang, Xiao‑Qin Zhu, Yong‑Sheng Tu

Published online on: September 27, 2017
Open Access

PDGF signaling pathway in hepatic fibrosis pathogenesis and therapeutics (Review)

Hua‑Zhong Ying, Qin Chen, Wen‑You Zhang, Huan‑Huan Zhang, Yue Ma, Song‑Zhao Zhang, Jie Fang, Chen‑Huan Yu

Published online on: September 27, 2017
Open Access

CISD2 promotes the proliferation of glioma cells via suppressing beclin‑1‑mediated autophagy and is targeted by microRNA‑449a

Ai‑Gang Sun, Fan‑Guo Meng, Ming‑Guang Wang

Published online on: September 27, 2017
Open Access

PARP‑1 may be involved in hydroquinone‑induced apoptosis by poly ADP‑ribosylation of ZO‑2

Jiaxian Liu, Qian Yuan, Xiaoxuan Ling, Qiang Tan, Hairong Liang, Jialong Chen, Lianzai Lin, Yongmei Xiao, Wen Chen, Linhua Liu, Huanwen Tang

Published online on: September 27, 2017

Expression of carbonic anhydrase III and skeletal muscle remodeling following selective denervation

He Huang, Yanling Zhao, Xiliang Shang, Xueyuan Liu, Huimin Ren

Published online on: September 27, 2017

Molecular mechanisms of the inhibitory effects of jiangu granule‑containing serum on RANKL‑induced osteoclastogenesis

Yunmei Huang, Yu Lin, Yinsheng Wu, Jianwei Zeng, Meiya Huang, Shiming Guo, Wenjuan Luo, Haiming Lin, Yanping Lin

Published online on: September 27, 2017
Open Access

Sanggenon C protects against cardiomyocyte hypoxia injury by increasing autophagy

Yang Gu, Lu Gao, Yu Chen, Zhuo Xu, Kun Yu, Dongying Zhang, Gang Zhang, Xiwen Zhang

Published online on: September 27, 2017

Mediating macrophage immunity with wogonin in mice with vascular inflammation

Jingwei Wang, Kunxia Li, Yupeng Li, Yulin Wang

Published online on: September 26, 2017
Open Access

Resveratrol inhibits proliferation and migration through SIRT1 mediated post‑translational modification of PI3K/AKT signaling in hepatocellular carcinoma cells

Rongfei Chai, Huiling Fu, Zhaodi Zheng, Tingting Liu, Shuhua Ji, Guorong Li

Published online on: September 26, 2017

Alterations in cyclin D1 and cyclin‑dependent kinase 4 expression in the amygdalae of post‑traumatic stress disorder rats

Ming Cong, Lili Wen, Fang Han, Yanhao Xu, Yuxiu Shi

Published online on: September 26, 2017

MicroRNA‑24‑1‑5p promotes malignant melanoma cell autophagy and apoptosis via regulating ubiquitin D

Yujuan Xiao, Qingchun Diao, Yanhua Liang, Yusheng Peng, Kang Zeng

Published online on: September 26, 2017

GRP78 positively regulates estrogen‑stimulated cell growth mediated by ER‑α36 in gastric cancer cells

Zhengqi Fu, Xuming Wang, Hongyan Zhou, Yan Li, Ying Chen, Zhaoyi Wang, Lijiang Liu

Published online on: September 26, 2017
Open Access

CD146+ skeletal stem cells from growth plate exhibit specific chondrogenic differentiation capacity in vitro

Ying‑Xing Wu, Xing‑Zhi Jing, Yue Sun, Ya‑Ping Ye, Jia‑Chao Guo, Jun‑Ming Huang, Wei Xiang, Jia‑Ming Zhang, Feng‑Jing Guo

Published online on: September 26, 2017

Complex role of connexin 43 in astrocytic tumors and possible promotion of glioma‑associated epileptic discharge (Review)

Hui Dong, Xing‑Wang Zhou, Xiang Wang, Yuan Yang, Jie‑Wen Luo, Yan‑Hui Liu, Qing Mao

Published online on: September 26, 2017
Open Access

Bioinformatics analysis of fibroblasts exposed to TGF‑β at the early proliferation phase of wound repair

Bobin Mi, Guohui Liu, Wu Zhou, Huijuan Lv, Kun Zha, Yi Liu, Qipeng Wu, Jing Liu

Published online on: September 26, 2017

Screening and validation of serum protein biomarkers for early postmenopausal osteoporosis diagnosis

Long Wang, Ya‑Qian Hu, Zhuo‑Jie Zhao, Hong‑Yang Zhang, Bo Gao, Wei‑Guang Lu, Xiao‑Long Xu, Xi‑Sheng Lin, Jin‑Peng Wang, Qiang Jie, Zhuo‑Jing Luo, Liu Yang

Published online on: September 26, 2017
Open Access

Identification of differentially expressed genes in Budd‑Chiari syndrome by RNA‑sequencing

Bin Yang, Dong Qu, An‑Li Zhao, Yu Li, Ran‑Ran Meng, Ji‑Xiang Yu, Peng Gao, Hua Peng Lin

Published online on: September 26, 2017
Open Access

Na+/K+‑ATPase DR region‑specific antibody protects U251 cells against hypoxia reperfusion‑induced injury via the PI3K/AKT and ERK pathways

Huilin Gong, Pengbiao Lü, Jiangwei Zhang, Dandong Li, Jin Zheng, Jinning Song

Published online on: September 26, 2017

Direct binding of RNF8 to SUMO2/3 promotes cell survival following DNA damage

Lili Liang, Zhenzhu Zhang, Jiandong Li, Jiaoxiang Wu, Likui Wang, Wenlin Huang, Shijuan Gao

Published online on: September 26, 2017

High-dose PMA with RANKL and MCSF induces THP‑1 cell differentiation into human functional osteoclasts in vitro

Zhuo Hao Li, Yu Si, Guo Xu, Xi Ming Chen, Hao Xiong, Lan Lai, Yi Qing Zheng, Zhi Gang Zhang

Published online on: September 26, 2017

Implantation of bone mesenchymal stem cells overexpressing miRNA‑705 mitigated ischemic brain injury

Meng Ji, Wei Wang, Shujuan Li, Wenli Hu

Published online on: September 26, 2017

Effects of Tripterygium glycoside treatment on experimental autoimmune encephalomyelitis

Jianmin Qiu, Xuelian You, Gang Wu

Published online on: September 26, 2017

Honokiol triggers receptor‑interacting protein kinase 3‑mediated cell death of neuroblastoma cells by upregulating reactive oxygen species

Jiao Zhang, Qiuliang Liu, Longyan Shi, Pan Qin, Qi Wang

Published online on: September 26, 2017

Chondromodulin‑I suppresses tumorigenesis of human osteosarcoma cells

Xiangbo Lin, Lijun Wang, Faming Wang

Published online on: September 26, 2017

Aberrant production of soluble inducible T cell co‑stimulator and soluble programmed cell death protein 1 in patients with chronic hepatitis B

Dongsheng Wang, Qin Du, Guangcheng Luo, Qiang Wang, Guangrong Wang, Guoyuan Zhang, Zhengwei Leng, Xiaolan Guo

Published online on: September 26, 2017

I‑BET151 inhibits osteoclastogenesis via the RANKL signaling pathway in RAW264.7 macrophages

Jing Cheng, Jifu Zheng, Ninghong Guo, Fuming Zi

Published online on: September 26, 2017

Baicalin potentiates TRAIL‑induced apoptosis through p38 MAPK activation and intracellular reactive oxygen species production

Lei Zhang, Xia Wang, Ruixue Wang, Xuelian Zheng, Na Li, Huannan Li, Xiaoren Cao, Bin Zhou, Yong Lin, Lan Yang

Published online on: September 26, 2017

PKCζ, MMP‑2 and MMP‑9 expression in lung adenocarcinoma and association with a metastatic phenotype

Xiaoshan Cai, Hongguang Zhu, Ying Li

Published online on: September 26, 2017

Network centrality in patients with acute unilateral open globe injury: A voxel‑wise degree centrality study

Hua Wang, Ting Chen, Lei Ye, Qi‑Chen Yang, Rong Wei, Ying Zhang, Nan Jiang, Yi Shao

Published online on: September 26, 2017
Open Access

The role of TGFβ‑HGF‑Smad4 axis in regulating the proliferation of mouse airway progenitor cells

Xue Li, Li Yang, Xin Sun, Junping Wu, Yu Li, Qiuyang Zhang, Yingchao Zhang, Kuan Li, Qi Wu, Huaiyong Chen

Published online on: September 26, 2017
Open Access

[Corrigendum] Nonsense-mediated mRNA decay factor Upf2 exists in both the nucleoplasm and the cytoplasm

Takanori Tatsuno, Yuka Nakamura, Shaofu Ma, Naohisa Tomosugi, Yasuhito Ishigaki

Published online on: September 25, 2017

Oleanolic acid alleviates diabetic rat carotid artery injury through the inhibition of NLRP3 inflammasome signaling pathways

Qian An, Qian Hu, Bing Wang, Wenjun Cui, Fei Wu, Yu Ding

Published online on: September 25, 2017
Open Access

Circadian gene hCLOCK contributes to progression of colorectal carcinoma and is directly regulated by tumor‑suppressive microRNA‑124

Jia‑Zi Yu, Ning Sun, Yi‑Bing Bei, Xiao‑Bo Li, Chao Lu, Lu‑Chun Hua

Published online on: September 25, 2017

SH003‑induced G1 phase cell cycle arrest induces apoptosis in HeLa cervical cancer cells

Kang Min Lee, Kangwook Lee, Youn Kyung Choi, Yu‑Jeong Choi, Hye‑Sook Seo, Seong‑Gyu Ko

Published online on: September 25, 2017

Total glucosides of paeony ameliorates TNBS‑induced colitis by modulating differentiation of Th17/Treg cells and the secretion of cytokines

Haihua Lin, Wenyou Zhang, Xuepei Jiang, Renpin Chen, Xielin Huang, Zhiming Huang

Published online on: September 25, 2017

Autophagy is activated to protect renal tubular epithelial cells against iodinated contrast media‑induced cytotoxicity

Na Liu, Rong Lei, Mi‑Mi Tang, Wei Cheng, Min Luo, Qian Xu, Shao‑Bin Duan

Published online on: September 25, 2017
Open Access

α7 nicotinic acetylcholine receptor agonist attenuates the cerebral injury in a rat model of cardiopulmonary bypass by activating the Akt/GSK3β pathway

Yingjie Sun, Dandan Song, Mei Wang, Keyan Chen, Tiezheng Zhang

Published online on: September 25, 2017

Hydrogen inhibits isoproterenol‑induced autophagy in cardiomyocytes in vitro and in vivo

Yaxing Zhang, Zhiyuan Long, Jingting Xu, Sihua Tan, Nan Zhang, Anfei Li, Ling Wang, Tinghuai Wang

Published online on: September 25, 2017

Effects of IQP, VEP and Spirulina platensis hydrolysates on the local kidney renin angiotensin system in spontaneously hypertensive rats

Jiahui Zheng, Jingyue Wang, Huanglei Pan, Hongli Wu, Difeng Ren, Jun Lu

Published online on: September 25, 2017

MicroRNA‑3666 inhibits breast cancer cell proliferation by targeting sirtuin 7

Di Li, Lifei Li

Published online on: September 25, 2017
Open Access

Placenta‑derived mesenchymal stem cells improve airway hyperresponsiveness and inflammation in asthmatic rats by modulating the Th17/Treg balance

Yingying Li, Hongbo Li, Yinyin Cao, Fuling Wu, Wenbin Ma, Yuesi Wang, Shuzhen Sun

Published online on: September 25, 2017
Open Access

Upregulation of long noncoding RNA AP003419.16 predicts high risk of aging‑associated idiopathic pulmonary fibrosis

Xiaoyan Hao, Yufeng Du, Li Qian, Dan Li, Xuejun Liu

Published online on: September 25, 2017
Open Access

Amygdalin ameliorates the progression of atherosclerosis in LDL receptor‑deficient mice

Jianzhen Lv, Wen Xiong, Tiantian Lei, Hailian Wang, Minghan Sun, Erwei Hao, Zhiping Wang, Xiaoqi Huang, Shaoping Deng, Jiagang Deng, Yi Wang

Published online on: September 25, 2017

Anti‑osteoporotic effects of tetramethylpyrazine via promoting osteogenic differentiation and inhibiting osteoclast formation

Long Wang, Wei‑Guang Lu, Jun Shi, Hong‑Yang Zhang, Xiao‑Long Xu, Bo Gao, Qiang Huang, Xiao‑Jie Li, Ya‑Qian Hu, Qiang Jie, Zhuo‑Jing Luo, Liu Yang

Published online on: September 25, 2017
Open Access

Periodic acid‑Schiff staining method for function detection of liver cells is affected by 2% horse serum in induction medium

Hui Hui, Wenjun Ma, Jiejie Cui, Mengjia Gong, Yi Wang, Yuanyuan Zhang, Tongchuan He, Yang Bi, Yun He

Published online on: September 22, 2017
Open Access

Cyclic helix B peptide protects HK‑2 cells from oxidative stress by inhibiting ER stress and activating Nrf2 signalling and autophagy

Long Li, Miao Lin, Lexi Zhang, Shang Huang, Chao Hu, Long Zheng, Liping Li, Chao Zhang, Cheng Yang, Yaqiu Long, Ruiming Rong, Tongyu Zhu

Published online on: September 22, 2017
Open Access

Evaluation of apoptosis induced by exposure to antineoplastic drugs in peripheral blood lymphocytes of nurses

Heng Liao, Lijie Bi, Jun Wei, Xin Song

Published online on: September 22, 2017
Open Access

Gene screening facilitates diagnosis of complicated symptoms: A case report

Hong Duan, Di Zhang, Jing Cheng, Yu Lu, Huijun Yuan

Published online on: September 22, 2017
Open Access

microRNA‑372 inhibits proliferation and induces apoptosis in human breast cancer cells by directly targeting E2F1

Ya‑Xin Zhao, Hua‑Cheng Liu, Wei‑Yang Ying, Cheng‑Yu Wang, Yao‑Jun Yu, Wei‑Jian Sun, Jie‑Fan Liu

Published online on: September 22, 2017

Baicalein protects tert‑butyl hydroperoxide‑induced hepatotoxicity dependent of reactive oxygen species removal

Ya‑Fang Wang, Zheng‑Hai Tang, Ting Li, Xiao‑Huang Xu, Xiuping Chen, Ying Wang, Yi‑Tao Wang, Jin‑Jian Lu

Published online on: September 22, 2017
Open Access

Quantum dot/pMHC multimers vs. phycoerythrin/pMHC tetramers for identification of HLA-A*0201-restricted pHBV core antigen18-27-specific T cells

Jianmeng Zhu, Yong Huang, Jing Su, Jian He, Yating Yu, Yongxiang Zhao, Xiaoling Lu

Published online on: August 1, 2017
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Print ISSN: 1791-2997
Online ISSN: 1791-3004

2016 Impact Factor: 1.692
Ranked #19/128 Medicine Research and Experimental
(total number of cites)

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