Endoscopic discrimination of sessile serrated adenomas from other serrated lesions

  • Authors:
    • Shin Hasegawa
    • Keiichi Mitsuyama
    • Hiroshi Kawano
    • Keiko Arita
    • Yasuhiko Maeyama
    • Yoshito Akagi
    • Yasutomo Watanabe
    • Yoshinobu Okabe
    • Osamu Tsuruta
    • Michio Sata
  • View Affiliations

  • Published online on: July 5, 2011     https://doi.org/10.3892/ol.2011.341
  • Pages: 785-789
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Abstract

Sessile serrated adenoma (SSA) is a proposed precursor of colorectal carcinogenesis. This study aimed to analyze the potential of endoscopy to discriminate SSA from other serrated lesions, specifically traditional serrated adenoma (TSA) and hyperplastic polyp (HP). Of 145 serrated lesions, 111 sessile serrated lesions including 32 TSAs, 25 SSAs and 54 HPs were analyzed for size, color, location and morphologic features using conventional endoscopy and magnifying chromoendoscopy. SSA was preferentially located in the right colon, whereas TSA and HP were located in the left colon. The sizes of SSA and TSA were larger than those of HP. The lesion color was indistinguishable among TSA, SSA and HP. Macroscopically, a pinecone-like or two-tier raised appearance were found more frequently in TSA than in SAA and HP. Under magnified chromoendoscopic observation, the stellar IIIL pit pattern and fern-like appearance were observed more frequently in TSA than in SAA and HP. In conclusion, endoscopic discrimination between SSA and other sessile serrated lesions based on morphological features was difficult. However, size and location of the lesions facilitated diagnosis.

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September-October 2011
Volume 2 Issue 5

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Spandidos Publications style
Hasegawa S, Mitsuyama K, Kawano H, Arita K, Maeyama Y, Akagi Y, Watanabe Y, Okabe Y, Tsuruta O, Sata M, Sata M, et al: Endoscopic discrimination of sessile serrated adenomas from other serrated lesions. Oncol Lett 2: 785-789, 2011.
APA
Hasegawa, S., Mitsuyama, K., Kawano, H., Arita, K., Maeyama, Y., Akagi, Y. ... Sata, M. (2011). Endoscopic discrimination of sessile serrated adenomas from other serrated lesions. Oncology Letters, 2, 785-789. https://doi.org/10.3892/ol.2011.341
MLA
Hasegawa, S., Mitsuyama, K., Kawano, H., Arita, K., Maeyama, Y., Akagi, Y., Watanabe, Y., Okabe, Y., Tsuruta, O., Sata, M."Endoscopic discrimination of sessile serrated adenomas from other serrated lesions". Oncology Letters 2.5 (2011): 785-789.
Chicago
Hasegawa, S., Mitsuyama, K., Kawano, H., Arita, K., Maeyama, Y., Akagi, Y., Watanabe, Y., Okabe, Y., Tsuruta, O., Sata, M."Endoscopic discrimination of sessile serrated adenomas from other serrated lesions". Oncology Letters 2, no. 5 (2011): 785-789. https://doi.org/10.3892/ol.2011.341