Stem cell‑mediated modulation of pyroptosis contributes to tissue repair in noninfective inflammatory‑related diseases (Review)

  • Authors:
    • Yi Wei
    • Li Li
    • Yiping Wang
    • Yan Chen
    • Zhengyang Li
    • Chufei Huang
    • Yangchen Wei
    • Chiyu Jia
    • Zuo Wang
    • Junlin Liao
  • View Affiliations

  • Published online on: March 29, 2024     https://doi.org/10.3892/ijmm.2024.5370
  • Article Number: 46
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Abstract

Pyroptosis, a programmed cell death marked by lytic and inflammatory characteristics, plays a crucial role in non‑infectious inflammation‑related diseases but can lead to detrimental outcomes when dysregulated. Stem cells have emerged as key players in modulating pyroptosis through paracrine signaling, offering a novel avenue for tissue repair and regeneration. The present review delved into previous studies elucidating the intricate interplay between stem cells and pyroptosis, emphasizing the potential of stem cell‑based therapies in regulating pyroptotic pathways. The exploration of this dynamic interaction holds promise for developing strategies to harness stem cells for effective tissue repair and regeneration in the context of inflammation‑related diseases.
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May-2024
Volume 53 Issue 5

Print ISSN: 1107-3756
Online ISSN:1791-244X

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Copy and paste a formatted citation
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Spandidos Publications style
Wei Y, Li L, Wang Y, Chen Y, Li Z, Huang C, Wei Y, Jia C, Wang Z, Liao J, Liao J, et al: Stem cell‑mediated modulation of pyroptosis contributes to tissue repair in noninfective inflammatory‑related diseases (Review). Int J Mol Med 53: 46, 2024
APA
Wei, Y., Li, L., Wang, Y., Chen, Y., Li, Z., Huang, C. ... Liao, J. (2024). Stem cell‑mediated modulation of pyroptosis contributes to tissue repair in noninfective inflammatory‑related diseases (Review). International Journal of Molecular Medicine, 53, 46. https://doi.org/10.3892/ijmm.2024.5370
MLA
Wei, Y., Li, L., Wang, Y., Chen, Y., Li, Z., Huang, C., Wei, Y., Jia, C., Wang, Z., Liao, J."Stem cell‑mediated modulation of pyroptosis contributes to tissue repair in noninfective inflammatory‑related diseases (Review)". International Journal of Molecular Medicine 53.5 (2024): 46.
Chicago
Wei, Y., Li, L., Wang, Y., Chen, Y., Li, Z., Huang, C., Wei, Y., Jia, C., Wang, Z., Liao, J."Stem cell‑mediated modulation of pyroptosis contributes to tissue repair in noninfective inflammatory‑related diseases (Review)". International Journal of Molecular Medicine 53, no. 5 (2024): 46. https://doi.org/10.3892/ijmm.2024.5370