Open Access

Arthritis caused by Cryptococcus neoformans infection: A case report

  • Authors:
    • Juan Min
    • Ying Zhao
    • Jie Du
    • Yongzhong Ning
    • Zhiqiang Wu
  • View Affiliations

  • Published online on: November 20, 2023     https://doi.org/10.3892/br.2023.1694
  • Article Number: 6
  • Copyright: © Min et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Cryptococcal infections are uncommon in individuals with normal immune functions. These infections commonly affect the lungs and central nervous system; however, there are a few reports of infection in the bone and joint areas. The current study reported a case of knee joint infection caused by Cryptococcus neoformans in China. A 56‑year‑old man presented to The China Academy of Chinese Medical Sciences Guang'anmen Hospital Baoding Hospital (Baoding, China) with severe anemia and lung inflammation. Initially, there was no obvious cause of swelling or pain in the knee joints. However, after the patient presented with new swollen and painful knee joint symptoms, pus culture and cryptococcal antigen detection tests confirmed C. neoformans infection. After pus drainage and fluconazole treatment, the patient's condition substantially improved. Clinical awareness of C. neoformans infections should be promoted. In suspected cases, puncture fluid or tissue pathogen testing should be performed as early as possible to avoid misdiagnosis and serious consequences of delayed treatment.
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Copy and paste a formatted citation
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Spandidos Publications style
Min J, Zhao Y, Du J, Ning Y and Wu Z: Arthritis caused by <em>Cryptococcus neoformans</em> infection: A case report. Biomed Rep 20: 6, 2024
APA
Min, J., Zhao, Y., Du, J., Ning, Y., & Wu, Z. (2024). Arthritis caused by <em>Cryptococcus neoformans</em> infection: A case report. Biomedical Reports, 20, 6. https://doi.org/10.3892/br.2023.1694
MLA
Min, J., Zhao, Y., Du, J., Ning, Y., Wu, Z."Arthritis caused by <em>Cryptococcus neoformans</em> infection: A case report". Biomedical Reports 20.1 (2024): 6.
Chicago
Min, J., Zhao, Y., Du, J., Ning, Y., Wu, Z."Arthritis caused by <em>Cryptococcus neoformans</em> infection: A case report". Biomedical Reports 20, no. 1 (2024): 6. https://doi.org/10.3892/br.2023.1694