Journal Articles
Review
Epimutation and cancer: a new carcinogenic mechanism of Lynch syndrome (Review)
Kouji Banno, Iori Kisu, Megumi Yanokura, Kosuke Tsuji, Kenta Masuda, Arisa Ueki, Yusuke Kobayashi, Wataru Yamagami, Hiroyuki Nomura, Eiichiro Tominaga, Nobuyuki Susumu, Daisuke Aoki
Pages: 793-797 Published online on: 25 June 2012
Review
Therapeutic potential of stem cells expressing suicide genes that selectively target human breast cancer cells: Evidence that they exert tumoricidal effects via tumor tropism (Review)
Bo-Rim Yi, Kelvin J. Choi, Seung U. Kim, Kyung-Chul Choi
Pages: 798-804 Published online on: 20 June 2012
Article
Tumor suppressive microRNA‑138 contributes to cell migration and invasion through its targeting of vimentin in renal cell carcinoma
Takeshi Yamasaki, Naohiko Seki, Yasutoshi Yamada, Hirofumi Yoshino, Hideo Hidaka, Takeshi Chiyomaru, Nijiro Nohata, Takashi Kinoshita, Masayuki Nakagawa, Hideki Enokida
Pages: 805-817 Published online on: 03 July 2012
Article
Artepillin C (3,5-diprenyl-4-hydroxycinnamic acid) sensitizes LNCaP prostate cancer cells to TRAIL-induced apoptosis
Ewelina Szliszka, Grzegorz Zydowicz, Elzbieta Mizgala, Wojciech Krol
Pages: 818-828 Published online on: 25 June 2012
Article
Expression of TMPRSS4 in non-small cell lung cancer and its modulation by hypoxia
Tri-Hung Nguyen, William Weber, Evis Havari, Timothy Connors, Rebecca G. Bagley, Rajashree McLaren, Prashant R. Nambiar, Stephen L. Madden, Beverly A. Teicher, Bruce Roberts, Johanne Kaplan, Srinivas Shankara
Pages: 829-838 Published online on: 12 June 2012
Article
Tob1 induces apoptosis and inhibits proliferation, migration and invasion of gastric cancer cells by activating Smad4 and inhibiting β‑catenin signaling
Juthika Kundu, S. M. Riajul Wahab, Joydeb Kumar Kundu, Yoon-La Choi, Ozgur Cem Erkin, Hun Seok Lee, Sang Gyu Park, Young Kee Shin
Pages: 839-848 Published online on: 12 June 2012
Article
Silibinin, a natural flavonoid, modulates the early expression of chemoprevention biomarkers in a preclinical model of colon carcinogenesis
Henriette Kauntz, Souad Bousserouel, Francine Gosse, Jacques Marescaux, Francis Raul
Pages: 849-854 Published online on: 25 June 2012
Article
Aldehyde dehydrogenase 1A1 confers intrinsic and acquired resistance to gemcitabine in human pancreatic adenocarcinoma MIA PaCa-2 cells
Hong-Quan Duong, Jae Seok Hwang, Hee Jeong Kim, Hyo Jin Kang, Yeon-Sun Seong, Insoo Bae
Pages: 855-861 Published online on: 12 June 2012
Article
Characterization of cells resistant to the potent histone deacetylase inhibitor spiruchostatin B (SP-B) and effect of overexpressed p21waf1/cip1 on the SP-B resistance or susceptibility of human leukemia cells
Syu-Ichi Kanno, Naoyuki Maeda, Ayako Tomizawa, Shin Yomogida, Tadashi Katoh, Masaaki Ishikawa
Pages: 862-868 Published online on: 06 June 2012
Article
MiR-23a regulates TGF-β-induced epithelial-mesenchymal transition by targeting E-cadherin in lung cancer cells
Mengru Cao, Masahiro Seike, Chie Soeno, Hideaki Mizutani, Kazuhiro Kitamura, Yuji Minegishi, Rintaro Noro, Akinobu Yoshimura, Li Cai, Akihiko Gemma
Pages: 869-875 Published online on: 28 June 2012
Article
Multiple myeloma cells expressing low levels of CD138 have an immature phenotype and reduced sensitivity to lenalidomide
Yawara Kawano, Shiho Fujiwara, Naoko Wada, Mikiko Izaki, Hiromichi Yuki, Yutaka Okuno, Kenichi Iyama, Hiroshi Yamasaki, Akira Sakai, Hiroaki Mitsuya, Hiroyuki Hata
Pages: 876-884 Published online on: 04 July 2012
Article
Cyclooxygenase-2 promotes tumor lymphangiogenesis and lymph node metastasis in oral squamous cell carcinoma
Yoshihiro Morita, Kenji Hata, Masako Nakanishi, Toshihiko Nishisho, Yoshiaki Yura, Toshiyuki Yoneda
Pages: 885-892 Published online on: 25 June 2012
Article
Oncolytic virotherapy for human bone and soft tissue sarcomas using live attenuated poliovirus
Satoru Atsumi, Akihiko Matsumine, Hidemi Toyoda, Rui Niimi, Takahiro Iino, Tomoki Nakamura, Takao Matsubara, Kunihiro Asanuma, Yoshihiro Komada, Atsumasa Uchida, Akihiro Sudo
Pages: 893-902 Published online on: 12 June 2012
Article
Transcatheter arterial infusion chemotherapy prior to radiofrequency thermal ablation for single hepatocellular carcinoma reduces the risk of intrahepatic distant recurrence
Hiroki Nishikawa, Yukio Osaki, Ryuichi Kita, Toru Kimura, Tadashi Inuzuka, Haruhiko Takeda, Jun Nakajima, Fumihiro Matsuda, Azusa Sakamoto, Shinichiro Henmi, Keiichi Hatamaru, Sumio Saito, Akihiro Nasu
Pages: 903-909 Published online on: 11 June 2012
Article
Decitabine, a DNA methyltransferase inhibitor, induces apoptosis in human leukemia cells through intracellular reactive oxygen species generation
Dong Yeok Shin, You-Soo Park, Kwangmo Yang, Gi-Young Kim, Wun-Jae Kim, Min Ho Han, Ho Sung Kang, Yung Hyun Choi
Pages: 910-918 Published online on: 05 July 2012
Article
Expression profiling of dipeptidyl peptidase 8 and 9 in breast and ovarian carcinoma cell lines
Claire H. Wilson, Catherine A. Abbott
Pages: 919-932 Published online on: 19 June 2012
Article
Frondoside A has an anti-invasive effect by inhibiting TPA-induced MMP-9 activation via NF-κB and AP-1 signaling in human breast cancer cells
Sun Young Park, Young Hun Kim, YoungHee Kim, Sang-Joon Lee
Pages: 933-940 Published online on: 14 June 2012
Article
Connexin 43 interacts with Bax to regulate apoptosis of pancreatic cancer through a gap junction-independent pathway
Yan Sun, Xiaoping Zhao, Yuting Yao, Xinyi Qi, Yaozong Yuan, Yu Hu
Pages: 941-948 Published online on: 20 June 2012
Article
Oridonin enhances antitumor activity of gemcitabine in pancreatic cancer through MAPK-p38 signaling pathway
He-Qi Bu, Jiang Luo, Hui Chen, Jian-Hong Zhang, Hong-Hai Li, Hong-Chun Guo, Zhao-Hong Wang, Sheng-Zhang Lin
Pages: 949-958 Published online on: 14 June 2012
Article
Mesenchymal stem cells play a potential role in regulating the establishment and maintenance of epithelial-mesenchymal transition in MCF7 human breast cancer cells by paracrine and induced autocrine TGF-β
Qilin Xu, Liang Wang, Hongling Li, Qin Han, Jing Li, Xuebin Qu, Shan Huang, Robert Chunhua Zhao
Pages: 959-968 Published online on: 03 July 2012
Article
Preferential inhibition of hepatocellular carcinoma by the flavonoid Baicalein through blocking MEK-ERK signaling
Rong-Rui Liang, Shu Zhang, Jun-An Qi, Zhi-Dong Wang, Jun Li, Pei-Jun Liu, Chen Huang, Xiao-Feng Le, Jun Yang, Zong-Fang Li
Pages: 969-978 Published online on: 06 June 2012
Article
Transcriptomic study of dormant gastrointestinal cancer stem cells
Shimpei Nishikawa, Dyah Laksmi Dewi, Hideshi Ishii, Masamitsu Konno, Naotsugu Haraguchi, Yoshihiro Kano, Takahito Fukusumi, Katsuya Ohta, Yuko Noguchi, Miyuki Ozaki, Daisuke Sakai, Taroh Satoh, Yuichiro Doki, Masaki Mori
Pages: 979-984 Published online on: 25 June 2012
Article
Identification of novel molecular targets regulated by tumor suppressive miR-375 induced by histone acetylation in esophageal squamous cell carcinoma
Yuka Isozaki, Isamu Hoshino, Nijiro Nohata, Takashi Kinoshita, Yasunori Akutsu, Naoyuki Hanari, Mikito Mori, Yasuo Yoneyama, Naoki Akanuma, Nobuyoshi Takeshita, Tetsuro Maruyama, Naohiko Seki, Norikazu Nishino, Minoru Yoshida, Hisahiro Matsubara
Pages: 985-994 Published online on: 28 June 2012
Article
RasGRF1 regulates proliferation and metastatic behavior of human alveolar rhabdomyosarcomas
Maciej Tarnowski, Gabriela Schneider, Gabriele Amann, Geoffrey Clark, Peter Houghton, Frederic G. Barr, Lukas Kenner, Mariusz Z. Ratajczak, Magda Kucia
Pages: 995-1004 Published online on: 28 June 2012
Article
Co-inhibition of microRNA-10b and microRNA-21 exerts synergistic inhibition on the proliferation and invasion of human glioma cells
Chang G. Dong, William K.K. Wu, Su Y. Feng, Xiao J. Wang, Jun F. Shao, Jian Qiao
Pages: 1005-1012 Published online on: 03 July 2012
Article
Systemic delivery of lentivirus-mediated secretable TAT-apoptin eradicates hepatocellular carcinoma xenografts in nude mice
Jin-Lu Ma, Su-Xia Han, Jing Zhao, Dan Zhang, Li Wang, Yao-Dong Li, Qing Zhu
Pages: 1013-1020 Published online on: 05 July 2012
Article
Expression and role of the inhibitor of apoptosis protein livin in chemotherapy sensitivity of ovarian carcinoma
Xiaomei Liu, Aiyuan Wang, Hong Gao, Zhengwei Yuan, Yisheng Jiao
Pages: 1021-1028 Published online on: 03 July 2012
Article
Correlation of EGFR, IDH1 and PTEN status with the outcome of patients with recurrent glioblastoma treated in a phase II clinical trial with the EGFR-blocking monoclonal antibody cetuximab
Shasha Lv, Erik Teugels, Jan Sadones, Sylvia De Brakeleer, Johnny Duerinck, Stephanie Du Four, Alex Michotte, Jacques De Grève, Bart Neyns
Pages: 1029-1035 Published online on: 29 June 2012
Article
Prospective impact of 5-FU in the induction of endoplasmic reticulum stress, modulation of GRP78 expression and autophagy in Sk-Hep1 cells
Anandam Kasin Yadunandam, Jin-Soo Yoon, Yeong‑Ae Seong, Chul-Woong Oh, Gun-Do Kim
Pages: 1036-1042 Published online on: 06 June 2012
Article
Expression of ADAMTS-1, ADAMTS-4, ADAMTS-5 and TIMP3 by hepatocellular carcinoma cell lines
Sharon L. Turner, David Mangnall, Nigel C. Bird, Rowena A.D. Bunning, Maria E. Blair-Zajdel
Pages: 1043-1049 Published online on: 20 June 2012
Article
Norcantharidin triggers cell death and DNA damage through S-phase arrest and ROS-modulated apoptotic pathways in TSGH 8301 human urinary bladder carcinoma cells
Chien-Chih Yu, Fang-Yu Ko, Chun-Shu Yu, Chin-Chung Lin, Yi‑Ping Huang, Jai-Sing Yang, Jing-Pin Lin, Jing-Gung Chung
Pages: 1050-1060 Published online on: 07 June 2012
Article
Autoantibodies against glucose-regulated protein 78 as serological diagnostic biomarkers in hepatocellular carcinoma
Qing Shao, Pengfei Ren, Yang Li, Bo Peng, Liping Dai, Ningjing Lei, Wu Yao, Gang Zhao, Linggen Li, Jianying Zhang
Pages: 1061-1067 Published online on: 12 June 2012
Article
Putative tumor metastasis-associated genes in human gastric cancer
Tsung-Fan Tuan, Cheng-Ta Chung, Hsiao-Hui Tsou, Fong-Wen Chen, Heng-Liang Lin, Yiu-Kay Lai, Wen-Sen Lee, Yu-Sheng Chao, Ling-Ling Hwang, Chiung-Tong Chen
Pages: 1068-1084 Published online on: 31 May 2012
Article
Evaluation of MAGE-A expression and grade of dysplasia for predicting malignant progression of oral leukoplakia
Jutta Ries, Abbas Agaimy, Elefterios Vairaktaris, Yeeun Kwon, Friedrich W. Neukam, Lei H. Strassburg, Emeka Nkenke
Pages: 1085-1093 Published online on: 26 June 2012
Article
Cytokine gene expression signature in ovarian clear cell carcinoma
Nozomu Yanaihara, Michael S. Anglesio, Kazunori Ochiai, Yukihiro Hirata, Misato Saito, Chie Nagata, Yasushi Iida, Satoshi Takakura, Kyosuke Yamada, Tadao Tanaka, Aikou Okamoto
Pages: 1094-1100 Published online on: 26 June 2012
Article
Sirtinol, a class III HDAC inhibitor, induces apoptotic and autophagic cell death in MCF-7 human breast cancer cells
Jing Wang, Tae Hyung Kim, Mee Young Ahn, Jaewon Lee, Jee H. Jung, Wahn Soo Choi, Byung Mu Lee, Kyuing Sil Yoon, Sungpil Yoon, Hyung Sik Kim
Pages: 1101-1109 Published online on: 26 June 2012
Article
Periostin activates integrin α5β1 through a PI3K/AKT‑dependent pathway in invasion of cholangiocarcinoma
Kusumawadee Utispan, Jumaporn Sonongbua, Peti Thuwajit, Siri Chau-In, Chawalit Pairojkul, Sopit Wongkham, Chanitra Thuwajit
Pages: 1110-1118 Published online on: 25 June 2012
Article
RL71, a second-generation curcumin analog, induces apoptosis and downregulates Akt in ER-negative breast cancer cells
Babasaheb Yadav, Sebastien Taurin, Lesley Larsen, Rhonda J. Rosengren
Pages: 1119-1127 Published online on: 15 June 2012
Article
Androgen-independent prostate cancer cells circumvent EGFR inhibition by overexpression of alternative HER receptors and ligands
Dolors Carrión-Salip, Clara Panosa, Javier A. Menendez, Teresa Puig, Glòria Oliveras, Atanasio Pandiella, Rafael De Llorens, Anna Massaguer
Pages: 1128-1138 Published online on: 06 June 2012
Article
A novel cancer/testis antigen KP-OVA-52 identified by SEREX in human ovarian cancer is regulated by DNA methylation
Kang-Mi Kim, Myung-Ha Song, Min-Ju Kim, Sayeema Daudi, Anthony Miliotto, Lloyd Old, Kunle Odunsi, Sang-Yull Lee
Pages: 1139-1147 Published online on: 06 June 2012
Article
Antitumor efficacy of sequential treatment with docetaxel and 5-fluorouracil against human oral cancer cells
Tetsuya Tamatani, Tarannum Ferdous, Natsumi Takamaru, Kanae Hara, Makoto Kinouchi, Nobuyuki Kuribayashi, Go Ohe, Daisuke Uchida, Hirokazu Nagai, Kenji Fujisawa, Youji Miyamoto
Pages: 1148-1156 Published online on: 04 July 2012
Article
Transactivation and reactivation capabilities of temperature-dependent p53 mutants in yeast and human cells
Jana Jagosova, Lenka Pitrova, Jana Slovackova, Barbora Ravcukova, Jan Smarda, Jana Smardova
Pages: 1157-1163 Published online on: 15 June 2012
Article
