Journal Articles
Article
Hereditary breast and ovarian cancer susceptibility genes (Review)
Hiroshi Kobayashi, Sumire Ohno, Yoshikazu Sasaki, Miyuki Matsuura
Pages: 1019-1029 Published online on: 19 June 2013
Article
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Perspective: Opportunities in recalcitrant, rare and neglected tumors
Beverly A. Teicher
Pages: 1030-1034 Published online on: 02 July 2013
Article
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Induction of apoptosis in MCF-7 cells by the hemagglutinin-neuraminidase glycoprotein of Newcastle disease virus Malaysian strain AF2240
Mohamed Ghrici, Mohamed El Zowalaty, Abdul Rahman Omar, Aini Ideris
Pages: 1035-1044 Published online on: 27 June 2013
Article
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Application of PCR methods to evaluate EGFR, KRAS and BRAF mutations in a small number of tumor cells in cytological material from lung cancer patients
Marzena Anna Lewandowska, Wojciech Jóźwicki, Cezary Jochymski, Janusz Kowalewski
Pages: 1045-1052 Published online on: 01 July 2013
Article
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Three missense mutations of DNA topoisomerase I in highly camptothecin-resistant colon cancer cell sublines
Yasuhiro Arakawa, Koji Ozaki, Yutaka Okawa, Hisashi Yamada
Pages: 1053-1058 Published online on: 05 July 2013
Article
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Cantharidin and norcantharidin inhibit the ability of MCF-7 cells to adhere to platelets via protein kinase C pathway-dependent downregulation of α2 integrin
Liu-Mei Shou, Qiong-Yan Zhang, Wei Li, Xin Xie, Kai Chen, Lian Lian, Zhen-Yu Li, Fei-Ran Gong, Ke-Sheng Dai, Yi-Xiang Mao, Min Tao
Pages: 1059-1066 Published online on: 08 July 2013
Article
Advantages of the rapid double-staining method for intraoperative detection of micrometastasis in sentinel lymph nodes
Toshihiko Ojima, Shinichi Kinami, Keishi Nakamura, Katsunobu Oyama, Masashi Inokuchi, Hideto Fujita, Itasu Ninomiya, Sachio Fushida, Takashi Fujimura, Seiko Kitamura, Shinichi Harada, Tetsuo Ohta
Pages: 1067-1072 Published online on: 04 July 2013
Article
Increased expression of α-actinin-4 is associated with unfavorable pathological features and invasiveness of bladder cancer
Hidehiko Yoshii, Keiichi Ito, Takako Asano, Akio Horiguchi, Masamichi Hayakawa, Tomohiko Asano
Pages: 1073-1080 Published online on: 01 July 2013
Article
Cetuximab promotes anticancer drug toxicity in rhabdomyosarcomas with EGFR amplification in vitro
Yuki Yamamoto, Kazumasa Fukuda, Yasushi Fuchimoto, Yumi Matsuzaki, Yoshiro Saikawa, Yuko Kitagawa, Yasuhide Morikawa, Tatsuo Kuroda
Pages: 1081-1086 Published online on: 04 July 2013
Article
Enhanced antitumor activity of trastuzumab emtansine (T-DM1) in combination with pertuzumab in a HER2-positive gastric cancer model
Yoriko Yamashita-Kashima, Sei Shu, Naoki Harada, Kaori Fujimoto-Ouchi
Pages: 1087-1093 Published online on: 19 June 2013
Article
A phase II study of a personalized peptide vaccination for chemotherapy-resistant advanced pancreatic cancer patients
Shigeru Yutani, Nobukazu Komatsu, Munehiro Yoshitomi, Satoko Matsueda, Koji Yonemoto, Takashi Mine, Masanori Noguchi, Yuki Ishihara, Akira Yamada, Kyogo Itoh, Tetsuro Sasada
Pages: 1094-1100 Published online on: 20 June 2013
Article
Adenosine potentiates the therapeutic effects of neural stem cells expressing cytosine deaminase against metastatic brain tumors
Wonyoung Kang, Ho Jun Seol, Dong-Ho Seong, Jandi Kim, Yonghyun Kim, Seung U. Kim, Do-Hyun Nam, Kyeung Min Joo
Pages: 1101-1106 Published online on: 03 July 2013
Article
Berberine induces apoptosis via the mitochondrial pathway in liver cancer cells
Novia K.Y. Yip, W. S. Ho
Pages: 1107-1112 Published online on: 19 June 2013
Article
Acquisition of paclitaxel resistance via PI3K‑dependent epithelial‑mesenchymal transition in A2780 human ovarian cancer cells
Fangfang Du, Xiaohong Wu, Yanjun Liu, Teng Wang, Xiaowei Qi, Yong Mao, Li Jiang, Yifei Zhu, Yun Chen, Ruiyu Zhu, Xiaofeng Han, Jian Jin, Xin Ma, Dong Hua
Pages: 1113-1118 Published online on: 26 June 2013
Article
Glutathione and glutathione peroxidase expression in breast cancer: An immunohistochemical and molecular study
Bruna Victorasso Jardim, Marina Gobbe Moschetta, Camila Leonel, Gabriela Bottaro Gelaleti, Vitor Rafael Regiani, Lívia Carvalho Ferreira, Juliana Ramos Lopes, Debora Ap. Pires de Campos Zuccari
Pages: 1119-1128 Published online on: 13 June 2013
Article
Pancreatic tumor mass in a xenograft mouse model is decreased by treatment with therapeutic stem cells following introduction of therapeutic genes
Doo-Jin Kim, Bo-Rim Yi, Hye-Rim Lee, Seung U. Kim, Kyung-Chul Choi
Pages: 1129-1136 Published online on: 25 June 2013
Article
CHD8 is an independent prognostic indicator that regulates Wnt/β-catenin signaling and the cell cycle in gastric cancer
Genta Sawada, Hiroki Ueo, Tae Matsumura, Ryutaro Uchi, Masahisa Ishibashi, Kosuke Mima, Junji Kurashige, Yusuke Takahashi, Sayori Akiyoshi, Tomoya Sudo, Keishi Sugimachi, Yuichiro Doki, Masaki Mori, Koshi Mimori
Pages: 1137-1142 Published online on: 08 July 2013
Article
Isolation and characterization of biliary epithelial and stromal cells from resected human cholangiocarcinoma: a novel in vitro model to study tumor-stroma interactions
Marco Massani, Tommaso Stecca, Luca Fabris, Ezio Caratozzolo, Cesare Ruffolo, Alberto Furlanetto, Stuart Morton, Massimiliano Cadamuro, Mario Strazzabosco, Nicolò Bassi
Pages: 1143-1148 Published online on: 26 June 2013
Article
The relevance of EGFR overexpression for the prediction of the malignant transformation of oral leukoplakia
Jutta Ries, Eleftherios Vairaktaris, Abbas Agaimy, Moritz Bechtold, Patricia Gorecki, Friedrich W. Neukam, Emeka Nkenke
Pages: 1149-1156 Published online on: 19 June 2013
Article
Overexpression of human telomerase reverse transcriptase promotes the motility and invasiveness of HepG2 cells in vitro
Peng-Cheng Chen, Ji-Run Peng, Lei Huang, Wen-Xia Li, Wen-Zhen Wang, Zhu-Qing-Qing Cui, Hui Han, Lei Gong, Da-Peng Xiang, Shi-Shi Qiao, Xin Yu, Yu-Hua Wei, Li-Ping Ma, Na Li, Ji-Ye Zhu, Xi-Sheng Leng
Pages: 1157-1164 Published online on: 25 June 2013
Article
Enhanced therapeutic efficacy of adenovirus-mediated interleukin-24 gene therapy combined with ionizing radiotherapy for nasopharyngeal carcinoma
Jisheng Liu, Yujuan Zhang, Peng Sun, Yufeng Xie, Jim Xiang, Jicheng Yang
Pages: 1165-1174 Published online on: 19 June 2013
Article
T-cell apoptosis induced by intratumoral activated hepatic stellate cells is associated with lung metastasis in hepatocellular carcinoma
Yun-Hong Xia, Zhi-Ming Wang, Rong-Xin Chen, Sheng-Long Ye, Rui-Xia Sun, Qiong Xue, Yong Huang
Pages: 1175-1184 Published online on: 27 June 2013
Article
Identification of molecular candidates and interaction networks via integrative toxicogenomic analysis in a human cell line following low-dose exposure to the carcinogenic metals cadmium and nickel
Jee Young Kwon, Jong-Il Weon, Preeyaporn Koedrith, Kang-Sik Park, Im Soon Kim, Young Rok Seo
Pages: 1185-1194 Published online on: 04 July 2013
Article
Ammonium chloride enhances cisplatin cytotoxicity through DNA double-strand breaks in human cervical cancer cells
Ye Xu, Ning Wang, Yan Ding, Chunyan Wang, Yang Yu, Shibing Liu, Xiaojun Wang, Zhixin Li
Pages: 1195-1200 Published online on: 20 June 2013
Article
EtBr-induced selective degradation of mitochondria occurs via autophagy
Yan Luo, Yide Hu, Minghui Zhang, Yu Xiao, Zongchang Song, Yu Xu
Pages: 1201-1208 Published online on: 04 July 2013
Article
Thymidine kinase/ganciclovir and cytosine deaminase/5-fluorocytosine suicide gene therapy-induced cell apoptosis in breast cancer cells
H. Kong, L. Tao, K. Qi, Y. Wang, Q. Li, J. Du, Z. Huang
Pages: 1209-1214 Published online on: 21 June 2013
Article
Prevalence of Th17 and Treg cells in gastric cancer patients and its correlation with clinical parameters
Qiaoxia Li, Qingjing Li, Jinxia Chen, Yu Liu, Xuefeng Zhao, Bibo Tan, Jun Ai, Zhiping Zhang, Jingjing Song, Baoen Shan
Pages: 1215-1222 Published online on: 27 June 2013
Article
Regulation of miR-155 affects pancreatic cancer cell invasiveness and migration by modulating the STAT3 signaling pathway through SOCS1
Chen Huang, Haidong Li, Weidong Wu, Tao Jiang, Zhengjun Qiu
Pages: 1223-1230 Published online on: 28 June 2013
Article
Induction of human leukemia U937 cell apoptosis by an ethanol extract of Dendropanax morbifera Lev. through the caspase-dependent pathway
Joon Wοο Lee, Cheol Park, Min Hο Han, Su Hyun Hong, Tae Kyung Lee, Shin Hwa Lee, Gi-Young Kim, Yung Hyun Choi
Pages: 1231-1238 Published online on: 19 June 2013
Article
MicroRNA-128 promotes cell-cell adhesion in U87 glioma cells via regulation of EphB2
Lina Lin, Xulin Chen, Xuelin Peng, Jianwen Zhou, Hsiang-Fu Kung, Marie C. Lin, Songshan Jiang
Pages: 1239-1248 Published online on: 05 July 2013
Article
Invasion potential of H22 hepatocarcinoma cells is increased by HMGB1-induced tumor NF-κB signaling via initiation of HSP70
Wei Gong, Zhi-Yong Wang, Guo-Xi Chen, Yu-Qiao Liu, Xiao-Yan Gu, Wen-Wei Liu
Pages: 1249-1256 Published online on: 05 July 2013
Article
Cordycepin increases sensitivity of Hep3B human hepatocellular carcinoma cells to TRAIL-mediated apoptosis by inactivating the JNK signaling pathway
Hye Hyeon Lee, Jin-Woo Jeong, Jun Hyuk Lee, Gi-Young Kim, Jaehun Cheong, Yong Kee Jeong, Young Hyun Yoo, Yung Hyun Choi
Pages: 1257-1264 Published online on: 04 July 2013
Article
Profiling of the calcitonin-calcitonin receptor axis in primary prostate cancer: clinical implications and molecular correlates
Arvind Thakkar, Irene V. Bijnsdorp, Albert A. Geldof, Girish V. Shah
Pages: 1265-1274 Published online on: 02 July 2013
Article
FAM9C plays an anti-apoptotic role through activation of the PI3K/Akt pathway in human hepatocellular carcinoma
Jun-Dong Zhou, Fei Shen, Jian-Song Ji, Kai Zheng, Min Huang, Jin-Chang Wu
Pages: 1275-1284 Published online on: 05 July 2013
Article
miR-21 and its target gene CCL20 are both highly overexpressed in the microenvironment of colorectal tumors: Significance of their regulation
Benjamin Vicinus, Claudia Rubie, Nathalie Stegmaier, Vilma Oliveira Frick, Kathrin Kölsch, Anne Kauffels, Pirus Ghadjar, Mathias Wagner, Matthias Glanemann
Pages: 1285-1292 Published online on: 01 July 2013
Article
Histone deacetylase 4 mediates SMAD family member 4 deacetylation and induces 5-fluorouracil resistance in breast cancer cells
Seong-Lan Yu, Dong Chul Lee, Ji Woong Son, Chang Gyo Park, Hoi Young Lee, Jaeku Kang
Pages: 1293-1300 Published online on: 01 July 2013
Article
Dual role of TGFBR3 in bladder cancer
Xiao-Long Liu, Kebing Xiao, Boxin Xue, Dongrong Yang, Zhe Lei, Yuxi Shan, Hong-Tao Zhang
Pages: 1301-1308 Published online on: 08 July 2013
Article
Total alkaloids of Rubus aleaefolius Poir. inhibit the STAT3 signaling pathway leading to suppression of proliferation and cell cycle arrest in a mouse model of hepatocellular carcinoma
Jinyan Zhao, Wei Lin, Zhiyun Cao, Liya Liu, Qunchuan Zhuang, Xiaoyong Zhong, Zhenfeng Hong, Jun Peng
Pages: 1309-1314 Published online on: 03 July 2013
Article
The overexpression of BAMBI and its involvement in the growth and invasion of human osteosarcoma cells
Lu Zhou, Jin Park, Kyu Yun Jang, Ho Sung Park, Sajeev Wagle, Kyu Hyun Yang, Kwang-Bok Lee, Byung-Hyun Park, Jung Ryul Kim
Pages: 1315-1322 Published online on: 26 June 2013
Article
Sirt3 is a tumor suppressor in lung adenocarcinoma cells
Kui Xiao, Jiehan Jiang, Wei Wang, Shan Cao, Liming Zhu, Huihui Zeng, Ruoyun Ouyang, Rui Zhou, Ping Chen
Pages: 1323-1328 Published online on: 08 July 2013
Article
Porphyromonas gingivalis lipopolysaccharide increases lipid accumulation by affecting CD36 and ATP-binding cassette transporter A1 in macrophages
Xiu-Ying Li, Chun Wang, Xue-Rong Xiang, Fang-Chun Chen, Cong-Ming Yang, Jing Wu
Pages: 1329-1336 Published online on: 08 July 2013
Article
The insulin-like growth factor-1 and expression of its binding protein‑3 in chronic hepatitis C and hepatocellular carcinoma
Agnieszka Adamek, Aldona Kasprzak, Hanna Mikoś, Wiesława Przybyszewska, Agnieszka Seraszek-Jaros, Arkadiusz Czajka, Karolina Sterzyńska, Iwona Mozer-Lisewska
Pages: 1337-1345 Published online on: 19 June 2013
Article
Sterol regulatory element-binding protein 1 is required for ovarian tumor growth
Long-Yun Nie, Qing-Tao Lu, Wei-Hua Li, Ning Yang, Samina Dongol, Xin Zhang, Jie Jiang
Pages: 1346-1354 Published online on: 28 June 2013
Article
GATA6 predicts prognosis and hepatic metastasis of colorectal cancer
Fei Shen, Jianglin Li, Wensong Cai, Guanghui Zhu, Weili Gu, Lin Jia, Bo Xu
Pages: 1355-1361 Published online on: 19 June 2013
Article
Ginsenoside Rg3 induces apoptosis in the U87MG human glioblastoma cell line through the MEK signaling pathway and reactive oxygen species
Yoon Ji Choi, Hyun Joo Lee, Dong Wan Kang, In Ho Han, Byung Kwan Choi, Won Ho Cho
Pages: 1362-1370 Published online on: 20 June 2013
Article
Reduced expression of mutS homolog 2 and mutL homolog 1 affects overall survival in laryngeal squamous cell carcinoma patients: Investigation into a potential cause
Hong-Li Gong, Yong Shi, Yi Shi, Chun-Ping Wu, Peng-Yu Cao, Liang Zhou, Chen Xu
Pages: 1371-1379 Published online on: 20 June 2013
Article
High CCR6/CCR7 expression and Foxp3+ Treg cell number are positively related to the progression of laryngeal squamous cell carcinoma
Bin Chen, Duo Zhang, Jian Zhou, Qing Li, Lin Zhou, Shi-Min Li, Li Zhu, Kuang-Yen Chou, Liang Zhou, Lei Tao, Li-Ming Lu
Pages: 1380-1390 Published online on: 08 July 2013
Article
Key genes and pathways in thyroid cancer based on gene set enrichment analysis
Wenwu He, Bin Qi, Qiuxi Zhou, Chuansen Lu, Qi Huang, Lei Xian, Mingwu Chen
Pages: 1391-1397 Published online on: 20 June 2013
Article
miR‑133a suppresses cell proliferation, migration and invasion in human lung cancer by targeting MMP‑14
Meng Xu, Yu‑Zhou Wang
Pages: 1398-1404 Published online on: 19 June 2013
Article
Antitumour effects of Yangzheng Xiaoji in human osteosarcoma: The pivotal role of focal adhesion kinase signalling
Wen G. Jiang, Lin Ye, Ke Ji, Fiona Ruge, Yiling Wu, Yong Gao, Jiafu Ji, Malcolm D. Mason
Pages: 1405-1413 Published online on: 03 July 2013
Article
Overexpression of astrocyte-elevated gene-1 is associated with cervical carcinoma progression and angiogenesis
Min Long, Ke Dong, Ping Gao, Xi Wang, Li Liu, Shuhui Yang, Fang Lin, Junxia Wei, Huizhong Zhang
Pages: 1414-1422 Published online on: 08 July 2013
Article
Notch1 destabilizes the adherens junction complex through upregulation of the Snail family of E-cadherin repressors in non-small cell lung cancer
Arum Kim, Eun Young Kim, Eun Na Cho, Hyung Jung Kim, Se Kyu Kim, Joon Chang, Chul Min Ahn, Yoon Soo Chang
Pages: 1423-1429 Published online on: 26 June 2013
Article
Inhibition of Wnt signaling induces cell apoptosis and suppresses cell proliferation in cholangiocarcinoma cells
Kun-Song Zhang, Qi Zhou, Ya-Feng Wang, Li-Jian Liang
Pages: 1430-1438 Published online on: 21 June 2013
Article
Patrinia scabiosaefolia inhibits colorectal cancer growth through suppression of tumor angiogenesis
Liwu Chen, Liya Liu, Ling Ye, Aling Shen, Youqin Chen, Thomas J. Sferra, Jun Peng
Pages: 1439-1443 Published online on: 02 July 2013
Article
Molecular basis for the regulation of hypoxia-inducible factor-1α levels by 2-deoxy-D-ribose
Ryuji Ikeda, Sho Tabata, Yusuke Tajitsu, Yukihiko Nishizawa, Kentaro Minami, Tatsuhiko Furukawa, Masatatsu Yamamoto, Yoshinari Shinsato, Shin-Ichi Akiyama, Katsushi Yamada, Yasuo Takeda
Pages: 1444-1448 Published online on: 27 June 2013
Article
Loss of the metastasis suppressor gene KiSS1 is associated with lymph node metastasis and poor prognosis in human colorectal cancer
Yoshinaga Okugawa, Yasuhiro Inoue, Koji Tanaka, Yuji Toiyama, Tadanobu Shimura, Masato Okigami, Aya Kawamoto, Junichiro Hiro, Susumu Saigusa, Yasuhiko Mohri, Keiichi Uchida, Masato Kusunoki
Pages: 1449-1454 Published online on: 20 June 2013
Article
Human erythropoietin increases the pro-angiogenic potential of A2780 ovarian adenocarcinoma cells under hypoxic conditions
Ján Kriška, Peter Solár, Lenka Varinská, Zuzana Solárová, Patrícia Kimáková, Ján Mojžiš, Peter Fedoročko, Arthur J. Sytkowski
Pages: 1455-1462 Published online on: 26 June 2013
Article
Predictive and prognostic factors in second- and third-line erlotinib treatment in NSCLC patients with known status of the EGFR gene
Paweł Krawczyk, Dariusz M. Kowalski, Kamila Wojas Krawczyk, Michał Szczyrek, Radosław Mlak, Andrzej Rolski, Aneta Szudy, Robert Kieszko, Kinga Winiarczyk, Janusz Milanowski, Maciej Krzakowski
Pages: 1463-1472 Published online on: 19 June 2013
Article
Artesunate exerts specific cytotoxicity in retinoblastoma cells via CD71
Fei Zhao, Han Wang, Patricilia Kunda, Xuemei Chen, Qiu-Ling Liu, Tao Liu
Pages: 1473-1482 Published online on: 28 June 2013
Article
Lentivirus-delivered short hairpin RNA targeting SNAIL inhibits HepG2 cell growth
Jing Liu, Gang Jiang, Shihai Liu, Zimin Liu, Huazheng Pan, Ruyong Yao, Jun Liang
Pages: 1483-1487 Published online on: 19 June 2013
Article
Microarray analysis reveals that high mobility group A1 is involved in colorectal cancer metastasis
Yusuke Takahashi, Genta Sawada, Tetsuya Sato, Junji Kurashige, Kosuke Mima, Tae Matsumura, Ryutaro Uchi, Hiroki Ueo, Masahisa Ishibashi, Yuki Takano, Sayuri Akiyoshi, Hidetoshi Eguchi, Tomoya Sudo, Keishi Sugimachi, Jun‑Ichi Tanaka, Shin-Ei Kudo, Yuichiro Doki, Masaki Mori, Koshi Mimori
Pages: 1488-1496 Published online on: 08 July 2013
Article
Aspirin antagonizes the cytotoxic effect of methotrexate in lung cancer cells
Kun-Huang Yan, Liang-Ming Lee, Mao-Chih Hsieh, Ming-De Yan, Chih-Jung Yao, Pey-Yi Chang, Tsung-Li Chen, Hwan-You Chang, Ann-Lii Cheng, Gi-Ming Lai, Shuang-En Chuang
Pages: 1497-1505 Published online on: 21 June 2013
Article
Cyclooxygenase-2 utilizes Jun N-terminal kinases to induce invasion, but not tamoxifen resistance, in MCF-7 breast cancer cells
Vianey Gonzalez-Villasana, Yolanda Gutiérrez-Puente, Ana M. Tari
Pages: 1506-1510 Published online on: 19 June 2013
Article
Promoter methylation of the DLC‑1 gene and its inhibitory effect on human colon cancer
Zhensheng Dai, Yueling Jin
Pages: 1511-1517 Published online on: 19 June 2013
Article