Thymoma, thymic hyperplasia, thymectomy and autoimmune diseases (Review)

  • Authors:
    • Y Sherer
    • Y BarDayan
    • Y Shoenfeld
  • View Affiliations

  • Published online on: May 1, 1997     https://doi.org/10.3892/ijo.10.5.939
  • Pages: 939-943
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Abstract

There is a bidirectional relationship between autoimmunity and cancer: on the one hand, patients with autoimmune conditions develop neoplastic diseases, and on the other hand, malignant conditions are associated with paraneoplastic autoimmune syndromes. Thymoma is an epithelial tumor which is often accompanied by autoimmune diseases: about a third of the patients with thymoma have myasthenia gravis. Pure red cell aplasia, pemphigus and systemic lupus erythematosus, might also coexist with this tumor. Thymectomy is an optional treatment in some autoimmune diseases (i.e. myasthenia gravis, multiple sclerosis, autoimmune hemolytic anemia, ulcerative colitis, and systemic lupus erythematosus). In this communication we review and discuss the coexistence of autoimmune diseases, thymoma or thymic hyperplasia, and the dual effects of thymectomy on their course.

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May 1997
Volume 10 Issue 5

Print ISSN: 1019-6439
Online ISSN:1791-2423

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Copy and paste a formatted citation
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Spandidos Publications style
Sherer Y, BarDayan Y and Shoenfeld Y: Thymoma, thymic hyperplasia, thymectomy and autoimmune diseases (Review). Int J Oncol 10: 939-943, 1997.
APA
Sherer, Y., BarDayan, Y., & Shoenfeld, Y. (1997). Thymoma, thymic hyperplasia, thymectomy and autoimmune diseases (Review). International Journal of Oncology, 10, 939-943. https://doi.org/10.3892/ijo.10.5.939
MLA
Sherer, Y., BarDayan, Y., Shoenfeld, Y."Thymoma, thymic hyperplasia, thymectomy and autoimmune diseases (Review)". International Journal of Oncology 10.5 (1997): 939-943.
Chicago
Sherer, Y., BarDayan, Y., Shoenfeld, Y."Thymoma, thymic hyperplasia, thymectomy and autoimmune diseases (Review)". International Journal of Oncology 10, no. 5 (1997): 939-943. https://doi.org/10.3892/ijo.10.5.939