Journal Articles

Open Access

Molecular mechanisms and clinical applications of miR-22 in regulating malignant progression in human cancer (Review)

Jingyu Wang, Yuan Li, Meiman Ding, Honghe Zhang, Xiaoming Xu, Jinlong Tang

Pages: 345-355 Published online on: 19 December 2016
Open Access

miR‑223‑3p regulates cell growth and apoptosis via FBXW7 suggesting an oncogenic role in human testicular germ cell tumors

Jikai Liu, Hao Shi, Xidan Li, Gang Chen, Catharina Larsson, Weng-Onn Lui

Pages: 356-364 Published online on: 15 December 2016
Open Access

AURKA, DLGAP5, TPX2, KIF11 and CKAP5: Five specific mitosis-associated genes correlate with poor prognosis for non-small cell lung cancer patients

Marc A. Schneider, Petros Christopoulos, Thomas Muley, Arne Warth, Ursula Klingmueller, Michael Thomas, Felix J.F. Herth, Hendrik Dienemann, Nikola S. Mueller, Fabian Theis, Michael Meister

Pages: 365-372 Published online on: 02 January 2017
Open Access

Nek2A/SuFu feedback loop regulates Gli-mediated Hedgehog signaling pathway

Fen Zhou, Dengliang Huang, Yong Li, Guanghui Hu, Hai Rao, Quqin Lu, Shiwen Luo, Yao Wang

Pages: 373-380 Published online on: 23 December 2016
Open Access

The protein arginine methyltransferase 5 promotes malignant phenotype of hepatocellular carcinoma cells and is associated with adverse patient outcomes after curative hepatectomy

Dai Shimizu, Mitsuro Kanda, Hiroyuki Sugimoto, Masahiro Shibata, Haruyoshi Tanaka, Hideki Takami, Naoki Iwata, Masamichi Hayashi, Chie Tanaka, Daisuke Kobayashi, Suguru Yamada, Goro Nakayama, Masahiko Koike, Michitaka Fujiwara, Tsutomu Fujii, Yasuhiro Kodera

Pages: 381-386 Published online on: 02 January 2017
Open Access

High Rab11-FIP4 expression predicts poor prognosis and exhibits tumor promotion in pancreatic cancer

Yun He, Mengsi Ye, Lingling Zhou, Yunfeng Shan, Guangrong Lu, Yuhui Zhou, Jinwei Zhong, Jihang Zheng, Zhanxiong Xue, Zhenzhai Cai

Pages: 396-404 Published online on: 30 December 2016
Open Access

NEK2 serves as a prognostic biomarker for hepatocellular carcinoma

Gang Li, Yanping Zhong, Qingrong Shen, Yi Zhou, Xiaofang Deng, Cuiping Li, Jiagui Chen, Ying Zhou, Min He

Pages: 405-413 Published online on: 03 January 2017
Open Access

Crude extract and solvent fractions of Calystegia soldanella induce G1 and S phase arrest of the cell cycle in HepG2 cells

Jung Im Lee, In-Hye Kim, Taek-Jeong Nam

Pages: 414-420 Published online on: 02 January 2017
Open Access

Upregulation of miR-146a by YY1 depletion correlates with delayed progression of prostate cancer

Yeqing Huang, Tao Tao, Chunhui Liu, Han Guan, Guangyuan Zhang, Zhixin Ling, Lei Zhang, Kai Lu, Shuqiu Chen, Bin Xu, Ming Chen

Pages: 421-431 Published online on: 05 January 2017
Open Access

A 22q11.2 amplification in the region encoding microRNA-650 correlates with the epithelial to mesenchymal transition in breast cancer primary cultures of Mexican patients

M. Lango-Chavarría, G. K. Chimal-Ramírez, M. E. Ruiz-Tachiquín, N. A. Espinoza-Sánchez, M. C. Suárez-Arriaga, E. M. Fuentes-Pananá

Pages: 432-440 Published online on: 05 January 2017

Downregulation of ST6GALNAC1 is associated with esophageal squamous cell carcinoma development

Takeshi Iwaya, Genta Sawada, Suburu Amano, Kohei Kume, Chie Ito, Fumitaka Endo, Masafumi Konosu, Yoshihiro Shioi, Yuji Akiyama, Takeshi Takahara, Koki Otsuka, Hiroyuki Nitta, Keisuke Koeda, Masaru Mizuno, Satoshi Nishizuka, Akira Sasaki, Koshi Mimori

Pages: 441-447 Published online on: 22 December 2016

Expression of ribophorine II is a promising prognostic factor in human gastric adenocarcinoma

Daisuke Fujimoto, Takanori Goi, Yasuo Hirono

Pages: 448-456 Published online on: 28 December 2016

Cancer-associated peritoneal mesothelial cells lead the formation of pancreatic cancer peritoneal dissemination

Toshiya Abe, Kenoki Ohuchida, Kazuhiro Koikawa, Sho Endo, Takashi Okumura, Masafumi Sada, Kohei Horioka, Biao Zheng, Taiki Moriyama, Kohei Nakata, Yoshihiro Miyasaka, Tatsuya Manabe, Takao Ohtsuka, Eishi Nagai, Kazuhiro Mizumoto, Makoto Hashizume, Masafumi Nakamura

Pages: 457-467 Published online on: 30 December 2016

Combining doxorubicin with a phenolic extract from flaxseed oil: Evaluation of the effect on two breast cancer cell lines

Eliana Guerriero, Angela Sorice, Francesca Capone, Gabriella Storti, Giovanni Colonna, Gennaro Ciliberto, Susan Costantini

Pages: 468-476 Published online on: 02 January 2017

Bortezomib induces apoptosis and suppresses cell growth and metastasis by inactivation of Stat3 signaling in chondrosarcoma

Xing Bao, Tingting Ren, Yi Huang, Chongmin Ren, Kang Yang, Hongliang Zhang, Wei Guo

Pages: 477-486 Published online on: 14 December 2016

Identification of microRNA-487b as a negative regulator of liver metastasis by regulation of KRAS in colorectal cancer

Tsuyoshi Hata, Yukako Mokutani, Hidekazu Takahashi, Akira Inoue, Koji Munakata, Kazuya Nagata, Naotsugu Haraguchi, Junichi Nishimura, Taishi Hata, Chu Matsuda, Kohei Murata, Tsunekazu Mizushima, Yuichiro Doki, Masaki Mori, Hirofumi Yamamoto

Pages: 487-496 Published online on: 20 December 2016

Comparative analysis of gene regulatory networks of highly metastatic breast cancer cells established by orthotopic transplantation and intra-circulation injection

Jun Nakayama, Emi Ito, Jiro Fujimoto, Shinya Watanabe, Kentaro Semba

Pages: 497-504 Published online on: 16 December 2016

CXCR4 is involved in CD133-induced EMT in non-small cell lung cancer

Zhenbo Tu, Songping Xie, Meng Xiong, Yinchu Liu, Xiangyong Yang, Kingsley Miyanda Tembo, Jie Huang, Weidong Hu, Xiaoxing Huang, Shan Pan, Pan Liu, Ehtisham Altaf, Ganjun Kang, Jie Xiong, Qiuping Zhang

Pages: 505-514 Published online on: 19 December 2016

The anti-angiogenic role of soluble-form VEGF receptor in malignant gliomas

Shingo Takano, Eiichi Ishikawa, Masahide Matsuda, Noriaki Sakamoto, Hiroyoshi Akutsu, Tetsuya Yamamoto, Akira Matsumura

Pages: 515-524 Published online on: 19 December 2016

Fructose-bisphosphate aldolase A is a key regulator of hypoxic adaptation in colorectal cancer cells and involved in treatment resistance and poor prognosis

Kenji Kawai, Mamoru Uemura, Koji Munakata, Hidekazu Takahashi, Naotsugu Haraguchi, Junichi Nishimura, Taishi Hata, Chu Matsuda, Masakazu Ikenaga, Kohei Murata, Tsunekazu Mizushima, Hirofumi Yamamoto, Yuichiro Doki, Masaki Mori

Pages: 525-534 Published online on: 20 December 2016

Silencing LPAATβ inhibits tumor growth of cisplatin-resistant human osteosarcoma in vivo and in vitro

Lei Song, Ping Duan, Yibo Gan, Pei Li, Chen Zhao, Jianzhong Xu, Zehua Zhang, Qiang Zhou

Pages: 535-544 Published online on: 28 December 2016

Puerarin inhibits M2 polarization and metastasis of tumor-associated macrophages from NSCLC xenograft model via inactivating MEK/ERK 1/2 pathway

Honggang Kang, Jing Zhang, Baozhong Wang, Meirong Liu, Jun Zhao, Mengxiang Yang, Yingxue Li

Pages: 545-554 Published online on: 05 January 2017

Activation of oncogenic pathways in classical Hodgkin lymphoma by decitabine: A rationale for combination with small molecular weight inhibitors

Tatjana Maria Swerev, Thomas Wirth, Alexey Ushmorov

Pages: 555-566 Published online on: 30 December 2016

Surgery management for sporadic small (≤2 cm), non-functioning pancreatic neuroendocrine tumors: a consensus statement by the Chinese Study Group for Neuroendocrine Tumors (CSNET)

Guang Yang, Meng Ji, Jie Chen, Rufu Chen, Ye Chen, Deliang Fu, Baohua Hou, Heguang Huang, Liming Jiang, Kaizhou Jin, Nengwen Ke, Ying Li, Yong Li, Houjie Liang, An'an Liu, Jie Luo, Quanxing Ni, Chengwei Shao, Boyong Shen, Weiqi Sheng, Bin Song, Jian Sun, Chunlu Tan, Huangying Tan, Qiyun Tang, Yingmei Tang, Xiaodong Tian, Jian Wang, Jie Wang, Wei Wang, Zheng Wu, Jin Xu, Qiang Yan, Ning Yang, Yinmo Yang, Xiaoyu Yin, Xianjun Yu, Chunhui Yuan, Shan Zeng, Guochao Zhang, Renchao Zhang, Zhiwei Zhou, Zhaohui Zhu, Chenghao Shao

Pages: 567-574 Published online on: 29 December 2016

Korean Byungkyul - Citrus platymamma Hort.et Tanaka flavonoids induces cell cycle arrest and apoptosis, regulating MMP protein expression in Hep3B hepatocellular carcinoma cells

Gyeong Eun Hong, Ho Jeong Lee, Jin A. Kim, Silvia Yumnam, Suchismita Raha, Venu Venkatarame Gowda Saralamma, Jeong Doo Heo, Sang Joon Lee, Eun Hee Kim, Chun Kil Won, Gon Sup Kim

Pages: 575-586 Published online on: 22 December 2016

Monoclonal antibodies targeting non-small cell lung cancer stem-like cells by multipotent cancer stem cell monoclonal antibody library

Kaiyue Cao, Yunzhi Pan, Long Yu, Xiong Shu, Jing Yang, Linxin Sun, Lichao Sun, Zhihua Yang, Yuliang Ran

Pages: 587-596 Published online on: 22 December 2016

Suicide gene therapy of rhabdomyosarcoma

Paweł Konieczny, Maciej Sułkowski, Bogna Badyra, Jacek Kijowski, Marcin Majka

Pages: 597-605 Published online on: 29 December 2016

PI3K inhibitor LY294002, as opposed to wortmannin, enhances AKT phosphorylation in gemcitabine-resistant pancreatic cancer cells

Yufeng Wang, Yasuhiro Kuramitsu, Byron Baron, Takao Kitagawa, Kazuhiro Tokuda, Junko Akada, Shin-Ichiro Maehara, Yoshihiko Maehara, Kazuyuki Nakamura

Pages: 606-612 Published online on: 14 December 2016

Multiple effects of ellagic acid on human colorectal carcinoma cells identified by gene expression profile analysis

Jinlu Zhao, Guodong Li, Wanlan Bo, Yuhui Zhou, Shuwei Dang, Jiufeng Wei, Xinglong Li, Ming Liu

Pages: 613-621 Published online on: 05 January 2017

ADAR2 functions as a tumor suppressor via editing IGFBP7 in esophageal squamous cell carcinoma

Yuan-Bin Chen, Xiao-Yu Liao, Jiang-Bo Zhang, Fang Wang, Hai-De Qin, Lanjun Zhang, Yin Yao Shugart, Yi-Xin Zeng, Wei-Hua Jia

Pages: 622-630 Published online on: 29 December 2016

CYR61/CCN1 stimulates proliferation and differentiation of osteoblasts in vitro and contributes to bone remodeling in vivo in myeloma bone disease

Hui Liu, Fengping Peng, Zhaoyun Liu, Fengjuan Jiang, Lijuan Li, Shan Gao, Guojin Wang, Jia Song, Erbao Ruan, Zonghong Shao, Rong Fu

Pages: 631-639 Published online on: 22 December 2016

Matrine suppresses invasion of castration-resistant prostate cancer cells by downregulating MMP-2/9 via NF-κB signaling pathway

Hai Huang, Tao Du, Guibin Xu, Yiming Lai, Xinxing Fan, Xianju Chen, Wenjiao Li, Fei Yue, Qi Li, Leyuan Liu, Kaiwen Li

Pages: 640-648 Published online on: 14 December 2016

131I-labeled monoclonal antibody targeting neuropilin receptor type-2 for tumor SPECT imaging

Lichun Chen, Liangliang Wang, Jianghua Yan, Chao Ma, Jing Lu, Guoqiang Chen, Shengyou Chen, Fu Su, Weixing Wang, Xinhui Su

Pages: 649-659 Published online on: 16 December 2016

Realgar transforming solution displays anticancer potential against human hepatocellular carcinoma HepG2 cells by inducing ROS

Peng Song, Peng Chen, Dong Wang, Zhengrong Wu, Qiyu Gao, Aixia Wang, Ruilan Zhu, Yajun Wang, Xin Wang, Longhe Zhao, Ziyun Duan, Shuqian Zhu, Peng Cui, Yang Li, Hongyu Li

Pages: 660-670 Published online on: 30 December 2016

Integrated analysis of microRNA and transcription factor reveals important regulators and regulatory motifs in adult B-cell acute lymphoblastic leukemia

Xiao-Cong Lin, Xin-Guang Liu, Yu-Ming Zhang, Ning Li, Zhi-Gang Yang, Wei-Yu Fu, Liu-Bo Lan, Hai-Tao Zhang, Yong Dai

Pages: 671-683 Published online on: 30 December 2016

Viscumins functionally modulate cell motility-associated gene expression

Sonja Schötterl, Miriam Hübner, Angela Armento, Vivien Veninga, Naita Maren Wirsik, Simon Bernatz, Hans Lentzen, Michel Mittelbronn, Ulrike Naumann

Pages: 684-696 Published online on: 03 January 2017

Identification of potential targets for differentiation in human leukemia cells induced by diallyl disulfide

Hui Ling, Jie He, Hui Tan, Lan Yi, Fang Liu, Xiaoxia Ji, Youhua Wu, Haobin Hu, Xi Zeng, Xiaohong Ai, Hao Jiang, Qi Su

Pages: 697-707 Published online on: 05 January 2017

Long non-coding RNA NEAT1 promotes malignant progression of thyroid carcinoma by regulating miRNA-214

Jian-Hua Li, Su-Qin Zhang, Xing-Guang Qiu, Shui-Jun Zhang, Shou-Hua Zheng, Dan-Hua Zhang

Pages: 708-716 Published online on: 14 December 2016

Histone deacetylases meet microRNA-associated MMP-9 expression regulation in glucocorticoid-sensitive and -resistant cell lines

Marwa Hentati-Kallel, Sébastien Le Jan, Philippe Bernard, Frank Antonicelli, Aurélie Trussardi-Régnier

Pages: 717-726 Published online on: 30 December 2016

The anti-metastatic effects of the phytoestrogen arctigenin on human breast cancer cell lines regardless of the status of ER expression

Thressi Maxwell, So-Young Chun, Kyu-Shik Lee, Soyoung Kim, Kyung-Soo Nam

Pages: 727-735 Published online on: 29 December 2016

Insulin induction instigates cell proliferation and metastasis in human colorectal cancer cells

Chi-Cheng Lu, Pei-Yi Chu, Shih-Min Hsia, Chi-Hao Wu, Yu-Tang Tung, Gow-Chin Yen

Pages: 736-744 Published online on: 05 January 2017
Open Access

[Corrigendum] Neutrophils in cancer development and progression: Roles, mechanisms, and implications (Review)

Xu Zhang, Wen Zhang, Xiao Yuan, Min Fu, Hui Qian, Wenrong Xu

Pages: 745-745 Published online on: 09 November 2016
Open Access

[Corrigendum] Increased expression levels of ppGalNAc-T13 in lung cancers: Significance in the prognostic diagnosis

Kenichi Nogimori, Tomoko Hori, Koji Kawaguchi, Takayuki Fukui, Shinji Mii, Hiroshi Nakada, Yasuyuki Matsumoto, Yoshio Yamauchi, Masahide Takahashi, Keiko Furukawa, Okajima Tetsuya, Kohei Yokoi, Yoshinori Hasegawa, Koichi Furukawa

Pages: 746-746 Published online on: 07 December 2016
Journal Cover

Cover Legend PDF

February 2017
Volume 50 Issue 2

Print ISSN: 1019-6439
Online ISSN: 1791-2423

2015 Impact Factor: 3.018
Ranked #30/211 Oncology
(total number of cites)

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