Metastatic tumors to the pancreas are a rare subtype of pancreatic malignant tumor, particularly those that have spread from the esophagus. The diagnosis and treatment process can be complex when managing patients with tumors that have metastasized to the pancreas. Accurate differentiation between primary pancreatic and metastatic tumors is key in the use of precision therapy for these patients. The present study reports the case of a 53‑year‑old female patient that presented with symptoms of dysphagia and epigastric pain that had persisted for 3 months. Gastroscopy indicated the presence of a tumor in the lower esophagus, with pathology results demonstrating squamous cell carcinoma. Prior to radical esophageal cancer surgery, computed tomography (CT) scans demonstrated the presence of a tumor in the body of the pancreas. Due to the notable size of the tumor and potential involvement of the large abdominal vessels, esophageal surgery was postponed and endoscopic ultrasound‑guided fine‑needle aspiration (EUS‑FNA) was performed to confirm the pathological diagnosis. EUS‑FNA pathological diagnosis demonstrated that the pancreatic tumor was a result of esophageal tumor metastasis. The patient opted for radiotherapy and chemotherapy for both the esophageal and pancreatic tumors instead of undergoing surgery. The present study reports the clinical and pathological characteristics, and treatment strategies of rare metastatic tumors to the pancreas of esophageal origin.

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