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Oncology Reports
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Print ISSN: 1021-335X Online ISSN: 1791-2431
Journal Cover
March 1997 Volume 4 Issue 2

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
March 1997 Volume 4 Issue 2

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Article

Increased polysomy 3 and 17 detected by fluorescence in situ hybridization (FISH) in oral squamous cell carcinoma

  • Authors:
    • T Tsuji
    • Y Mimura
    • A Kanekawa
    • M Okafuji
    • T Kamata
    • T Murakami
    • K Sasaki
    • F Shinozaki

  • View Affiliations / Copyright

    Affiliations: YAMAGUCHI UNIV,SCH MED,DEPT PATHOL,UBE,YAMAGUCHI 755,JAPAN. YAMAGUCHI UNIV,SCH MED,DEPT OTOLARYNGOL,UBE,YAMAGUCHI 755,JAPAN. YAMAGUCHI PREFECTURAL CENT HOSP,DIV ORAL & MAXILLOFACIAL SURG,HOFU,JAPAN.
  • Pages: 277-280
    |
    Published online on: March 1, 1997
       https://doi.org/10.3892/or.4.2.277
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Abstract

Numerical chromosome aberrations were studied by fluorescence in situ hybridization (FISH) using pericentromeric DNA probes specific for chromosomes 3 and 17 in 18 oral squamous cell carcinomas (SCCs) and 3 lymph nodes as control. Disomy 3 and 17 was detected in approximately 90% of control cells, and in 60.9 +/- 4.0% and 62.7 +/- 3.6% of SCCs, respectively. Polysomy 3 and 17 significantly increased in SCCs when compared to controls. The pattern of chromosome aberrations varied considerably between cases. There was no obvious relationship between the degree of polysomies and clinicopathological factors such as tumor-differentiation, stage of the disease and clinical outcome. Chromosome aberrations by FISH did not correlate with DNA aneuploidy by flow cytometry. Our results indicate that oral SCCs are more frequently associated with the increased copy number of chromosomes 3 and 17 than previously thought, and that a correlation between chromosome aberrations by FISH and DNA aneuploidy by flow cytometry is not obvious.

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Copy and paste a formatted citation
Spandidos Publications style
Tsuji T, Mimura Y, Kanekawa A, Okafuji M, Kamata T, Murakami T, Sasaki K and Shinozaki F: Increased polysomy 3 and 17 detected by fluorescence in situ hybridization (FISH) in oral squamous cell carcinoma. Oncol Rep 4: 277-280, 1997.
APA
Tsuji, T., Mimura, Y., Kanekawa, A., Okafuji, M., Kamata, T., Murakami, T. ... Shinozaki, F. (1997). Increased polysomy 3 and 17 detected by fluorescence in situ hybridization (FISH) in oral squamous cell carcinoma. Oncology Reports, 4, 277-280. https://doi.org/10.3892/or.4.2.277
MLA
Tsuji, T., Mimura, Y., Kanekawa, A., Okafuji, M., Kamata, T., Murakami, T., Sasaki, K., Shinozaki, F."Increased polysomy 3 and 17 detected by fluorescence in situ hybridization (FISH) in oral squamous cell carcinoma". Oncology Reports 4.2 (1997): 277-280.
Chicago
Tsuji, T., Mimura, Y., Kanekawa, A., Okafuji, M., Kamata, T., Murakami, T., Sasaki, K., Shinozaki, F."Increased polysomy 3 and 17 detected by fluorescence in situ hybridization (FISH) in oral squamous cell carcinoma". Oncology Reports 4, no. 2 (1997): 277-280. https://doi.org/10.3892/or.4.2.277
Copy and paste a formatted citation
x
Spandidos Publications style
Tsuji T, Mimura Y, Kanekawa A, Okafuji M, Kamata T, Murakami T, Sasaki K and Shinozaki F: Increased polysomy 3 and 17 detected by fluorescence in situ hybridization (FISH) in oral squamous cell carcinoma. Oncol Rep 4: 277-280, 1997.
APA
Tsuji, T., Mimura, Y., Kanekawa, A., Okafuji, M., Kamata, T., Murakami, T. ... Shinozaki, F. (1997). Increased polysomy 3 and 17 detected by fluorescence in situ hybridization (FISH) in oral squamous cell carcinoma. Oncology Reports, 4, 277-280. https://doi.org/10.3892/or.4.2.277
MLA
Tsuji, T., Mimura, Y., Kanekawa, A., Okafuji, M., Kamata, T., Murakami, T., Sasaki, K., Shinozaki, F."Increased polysomy 3 and 17 detected by fluorescence in situ hybridization (FISH) in oral squamous cell carcinoma". Oncology Reports 4.2 (1997): 277-280.
Chicago
Tsuji, T., Mimura, Y., Kanekawa, A., Okafuji, M., Kamata, T., Murakami, T., Sasaki, K., Shinozaki, F."Increased polysomy 3 and 17 detected by fluorescence in situ hybridization (FISH) in oral squamous cell carcinoma". Oncology Reports 4, no. 2 (1997): 277-280. https://doi.org/10.3892/or.4.2.277
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