Solitary plasmacytoma of the skull: Two case reports
- Authors:
- Lun Dong
- Xian Zhang
- Hengzhu Zhang
- Ruihong Song
- Xuewen Gu
- Liang He
View Affiliations
Affiliations: Department of Neurosurgery, Clinical Medical College, Yangzhou University, Yangzhou 225001, Jiangsu, P.R. China, Department of Pathology, Clinical Medical College, Yangzhou University, Yangzhou 225001, Jiangsu, P.R. China
- Published online on: November 26, 2012 https://doi.org/10.3892/ol.2012.1046
-
Pages:
479-482
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Abstract
Solitary plasmacytoma of the skull is rare and few cases have been reported in the English literature.Plasmacytoma of the skull has a wide spectrum of pathology, including a quite benign, solitary plasmacytoma (SPC), and an extremely malignant, multiple myeloma (MM) at the two ends of the spectrum. The prognosis for solitary plasmacytoma of the skull appears to be good when it can be diagnosed on strict criteria. The clinical features of solitary plasmacytoma of the skull are complex and not easily identified, resulting in a high misdiagnosis rate. A comprehensive examination and analysis which includes radiological examination, immunoglobulin, biochemistry, test for Bence Jones protein in the urine and bone marrow is needed for correct diagnosis. If the skull lesion is isolated, with accompanying marked swelling in the area and tenderness, plasmacytoma must be considered as a possibility for the cause of solitary skull masses. Two cases of solitary plasmacytoma of the skull lesions were retrospectively reviewed, in which a comprehensive examination was used in order to predict the clinical course of solitary plasmacytoma of the skull. The patients received postoperative radiation and/or chemotherapy. Survival following surgery was longer than 2 years for patient 1, and patient 2 is alive at the 18-month follow-up.
View References
|
1.
|
Joshi A, Jiang D, Singh P and Moffat D:
Skull base presentation of multiple myeloma. Ear Nose Throat J.
90:E6–E9. 2011.PubMed/NCBI
|
|
2.
|
George ED and Sadovsky R: Multiple
myeloma: recognition and management. Am Fam Physician.
59:1885–1894. 1999.PubMed/NCBI
|
|
3.
|
Wein RO, Popat SR, Doerr TD and Dutcher
PO: Plasma cell tumors of the skull base: four case reports and
literature review. Skull Base. 12:77–86. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
4.
|
Tanaka M, Shibui S, Nomura K and Nakanishi
Y: Solitary plasmacytoma of the skull: a case report. Jpn J Clin
Oncol. 28:626–30. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
5.
|
Naganuma H, Sakatsume S, Sugita M, Satoh
E, Asahara T and Nukui H: Solitary plasmacytoma of the skull:
immunohistochemical study of angiogenic factors and syndecan-1 -
two case reports. Neurol Med Chir (Tokyo). 44:195–200. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
6.
|
Hotta T: Classification, staging and
prognostic indices for multiple myeloma. Nihon Rinsho.
65:2161–2166. 2007.(In Japanese).
|
|
7.
|
International Myeloma Working Group:
Criteria for the classification of monoclonal gammopathies,
multiple myeloma and related disorders: a report of the
International Myeloma Working Group. Br J Haematol. 121:749–757.
2003. View Article : Google Scholar : PubMed/NCBI
|
|
8.
|
Lorsbach RB, Hsi ED, Dogan A and Fend F:
Plasma cell myeloma and related neoplasms. Am J Clin Pathol.
136:168–182. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
9.
|
Kyle RA, Therneau TM, Rajkumar SV, et al:
Incidence of multiple myeloma in Olmsted County, Minnesota: Trend
over 6 decades. Cancer. 101:2667–2674. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
10.
|
Shaheen SP, Talwalkar SS and Medeiros LJ:
Multiple myeloma and immunosecretory disorders: an update. Adv Anat
Pathol. 15:196–210. 2008. View Article : Google Scholar : PubMed/NCBI
|
