Limb graft occlusion following endovascular aortic repair: Incidence, causes, treatment and prevention in a study cohort

Wang,Guoquan; Zhai,Shuiting; Li,Tianxiao; Li,Xuan; Lu,Danghui; Wang,Bo; Zhang,Dongbin; Shi,Shuaitao; Zhang,Zhidong; Liang,Kai; Zhang,Kewei; Fu,Xiaoyang; Li,Kun; Li,Weixiao

doi:10.3892/etm.2017.4658

Limb graft occlusion following endovascular aortic repair: Incidence, causes, treatment and prevention in a study cohort

Authors:
- Guoquan Wang
- Shuiting Zhai
- Tianxiao Li
- Xuan Li
- Danghui Lu
- Bo Wang
- Dongbin Zhang
- Shuaitao Shi
- Zhidong Zhang
- Kai Liang
- Kewei Zhang
- Xiaoyang Fu
- Kun Li
- Weixiao Li
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Affiliations: Department of Vascular and Endovascular Surgery, Henan Provincial Peoples' Hospital, Zhengzhou University, Zhengzhou, Henan 450003, P.R. China, Department of Vascular and Endovascular Surgery, Peking University Third Hospital, Beijing 100191, P.R. China
Published online on: June 23, 2017 https://doi.org/10.3892/etm.2017.4658
Pages: 1763-1768

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Abstract

The present study investigated the incidence, causes, treatment and prevention of limb graft occlusion following endovascular aortic repair (EVAR). A total of 66 cases of abdominal aortic aneurysm receiving EVAR at our department from January 2005 to December 2013 were enrolled. After EVAR, patients received routine antiplatelet therapy of 75 mg PLAVIX for 6 months and then 100 mg Aspirin for another 6 months by oral administration. According to previous clinical experiences, antiplatelet therapy is able to effectively reduce the incidence of iliac occlusion after EVAR. A total of 61 bifurcated grafts and 5 aortauniilac grafts (127 limbs in total) were used. Physical examination, ankle-brachial-index and computer tomographic angiography were performed at 10 days, at 3, 6 and 12 months and annually thereafter. It was found that 7 limbs in 7 patients (10.6% of patients, 5.5% of limbs) were occluded between 20 days and 12 months (average, 7.8±5.3 months) after EVAR. Acute and severe ischemia was found in 2 cases, claudication was in found 3 cases, asthenia in both legs was found in 1 case and 1 case was asymptomatic. Femoral‑femoral bypass, femoral‑femoral bypass and stenting, aorto‑iliac/femoral bypass, thrombectomy and conservative treatment were performed in 1 patient each and thrombectomy together with stenting was performed in 2 cases. Limb graft occlusion was not rare after EVAR. Treatment of this complication included surgery and endovascular therapy such as bypass, thrombectomy and thrombolysis. In conclusion, aggressive pre‑emptive treatment including angioplasty and stenting prevented occlusion in certain cases.

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