Dietary vitamin intake and risk of metabolic syndrome among centenarians in China

Peng,Zhiqing; Wang,Yanyan; Huang,Xianyong; Zhu,Qiao; Zhao,Yali; Xie,Hengge; Wu,Jianjun

doi:10.3892/etm.2020.9537

Dietary vitamin intake and risk of metabolic syndrome among centenarians in China

Authors:
- Zhiqing Peng
- Yanyan Wang
- Xianyong Huang
- Qiao Zhu
- Yali Zhao
- Hengge Xie
- Jianjun Wu
View Affiliations

Affiliations: Department of Clinical Nutrition, Hainan Hospital of Chinese PLA General Hospital, Sanya, Hainan 572000, P.R. China, Department of Healthcare, Hainan Hospital of Chinese PLA General Hospital, Sanya, Hainan 572000, P.R. China, Department of Central Laboratory, Hainan Hospital of Chinese PLA General Hospital, Sanya, Hainan 572000, P.R. China, Department of Geriatric Neurology, The Second Medical Center, Chinese PLA General Hospital/National Clinical Research Center for Geriatric Diseases, Beijing 100853, P.R. China
Published online on: November 27, 2020 https://doi.org/10.3892/etm.2020.9537
Article Number: 105

Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )

Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )

Cited By (CrossRef): 0 citations Loading Articles...

Abstract

The present study aimed to investigate dietary vitamin intake levels and their association with the prevalence of obesity, hypertension, dyslipidemia and hyperglycemia in centenarians in China. From June 2014 to December 2016, a total of 992 centenarians aged >99 years (177 males and 815 females; age range, 100‑115 years) were enrolled through household visits in the cities and rural areas of Hainan province. Details regarding food intake were recorded by continuous collection of 7‑day food frequency and 24‑h dietary review, and dietary vitamin intake levels were calculated according to the Chinese Food Composition Table. The deficiency rates of vitamin A (VA), VE, VB1, VB2, niacin and VC among the centenarians were relatively high and the prevalence of metabolic syndrome (MS) was 53.67% (519/967). The dietary intake levels of VA, VE and PP were significantly higher among the healthy centenarians than among the centenarians with MS (P<0.05). Compared with the lowest quartiles (Q1) of dietary vitamin intake, higher dietary intake levels of VA (Q4) [odds ratio (OR)=0.72; 95% CI: 0.38, 0.99], VE (Q3) (OR=0.61; 95% CI=0.36, 0.88) and VB2 (Q4) (OR=0.51; 95% CI: 0.32, 0.81) were associated with a reduced risk of hypertension (P<0.05). However, higher dietary intake levels of VA, VE, VB2 and PP were associated with increased risks of central obesity, hyperglycemia and low high‑density lipoprotein cholesterol levels. A high prevalence of MS and vitamin deficiency were detected among the centenarians and these two items were associated with each other. It was indicated that specific vitamins are necessary for certain centenarians.

View Figures

View References

1	Sun CH: Nutrients and foods Hygienics. People's Medical Publishing House Co. Ltd., Beijing, 2012.
2	Fletcher RH and Fairfield KM: Vitamins for chronic disease prevention in adults: Clinical applications. JAMA. 287:3127–3129. 2002.PubMed/NCBI View Article : Google Scholar
3	He Y, Zhao Y, Yao Y, Yang S, Li J, Liu M, Chen X, Wang J, Zhu Q, Li X, et al: Cohort profile: The China Hainan Centenarian Cohort Study (CHCCS). Int J Epidemiol. 47:694–695. 2018.PubMed/NCBI View Article : Google Scholar
4	He Y, Luan FX, Yao Y, Yang SS, Xie HG, Li J, Liu M, Wang JH, Wu L, Zhu Q, et al: China Hainan Centenarian Cohort Study: Study design and preliminary results. Zhonghua Liu Xing Bing Xue Za Zhi. 38:1292–1298. 2017.PubMed/NCBI View Article : Google Scholar : (In Chinese).
5	Vitezova A, Zillikens MC, van Herpt TT, Sijbrands EJ, Hofman A, Uitterlinden AG, Franco OH and Kiefte-de Jong JC: Vitamin D status and metabolic syndrome in the elderly: The Rotterdam Study. Eur J Endocrinol. 172:327–335. 2015.PubMed/NCBI View Article : Google Scholar
6	Ford ES, Ajani UA, McGuire LC and Liu S: Concentrations of serum vitamin D and the metabolic syndrome among U.S. Adults. Diabetes Care. 28:1228–1230. 2005.PubMed/NCBI View Article : Google Scholar
7	Thomas-Valdés S, Tostes MDGV, Anunciação PC, da Silva BP and Sant'Ana HMP: Association between vitamin deficiency and metabolic disorders related to obesity. Crit Rev Food Sci Nutr. 57:3332–3343. 2017.PubMed/NCBI View Article : Google Scholar
8	Hausman DB, Fischer JG and Johnson MA: Nutrition in centenarians. Maturitas. 68:203–209. 2011.PubMed/NCBI View Article : Google Scholar
9	D'Ambrosio DN, Clugston RD and Blaner WS: Vitamin A metabolism: An update. Nutrients. 3:63–103. 2011.PubMed/NCBI View Article : Google Scholar
10	Rozing MP, Westendorp RG, de Craen AJ, Frölich M, de Goeij MC, Heijmans BT, Beekman M, Wijsman CA, Mooijaart SP, Blauw GJ, et al: Favorable glucose tolerance and lower prevalence of metabolic syndrome in offspring without diabetes mellitus of nonagenarian siblings: The Leiden longevity study. J Am Geriatr Soc. 58:564–569. 2010.PubMed/NCBI View Article : Google Scholar
11	Ostan R, Bucci L, Cevenini E, Palmas MG, Pini E, Scurti M, Vescovini R, Caruso C, Mari D, Vitale G, et al: Metabolic syndrome in the offspring of centenarians: Focus on prevalence, components, and adipokines. Age (Dordr). 35:1995–2007. 2013.PubMed/NCBI View Article : Google Scholar
12	Hao Z, Liu Y, Li Y, Song W, Yu J, Li H and Wang W: Association between Longevity and element levels in food and drinking water of typical Chinese Longevity Area. J Nutr Health Aging. 20:897–903. 2016.PubMed/NCBI View Article : Google Scholar
13	Yang YX, Wang GY and Pan XC: China Food Composition. Peking University Medical Press, Beijing, 2002.
14	Grundy SM, Cleeman JI, Daniels SR, Donato KA, Eckel RH, Franklin BA, Gordon DJ, Krauss RM, Savage PJ, Smith SC Jr, et al: Diagnosis and management of the metabolic syndrome: An American Heart Association/National Heart, Lung, and blood institute scientific statement. Circulation. 112:2735–2752. 2005.PubMed/NCBI View Article : Google Scholar
15	Chen CM and Kong LZ: Guidelines for the Prevention and Control of Overweight and Obesity in Chinese Adults. People's Medical Publishing House Co. Ltd., Beijing, 2006.
16	Wang W: Guidelines for primary management of hypertension in China (2014 revision). Zhonghua Gao Xue Ya Za Zhi. 23:24–43. 2015.(In Chinese).
17	Han QX, Zhang D, Zhao YL, Liu L, Li J, Zhang F, Luan FX, Liu DW, Liu ZS, Cai GY, et al: Risk factors for hyperuricemia in Chinese Centenarians and Near-Centenarians. Clin Interv Aging. 14:2239–2247. 2019.PubMed/NCBI View Article : Google Scholar
18	Society CN: Reference intake of dietary nutrients for Chinese residents. China Science Publishing & Media Ltd., Beijing, 2014.
19	Zhou HT, Wang SK, Yin X, et al: Nutrition and health status of elderly population in Lishui district of Nanjing in China. Chong Qing Yi Xue Chongqing Med. 43:3333–3335. 2014.
20	Zhang RH, Zhou B, Zhu XH, Huang LC, Zhu YB and Ding GQ: The relationship between vitamin intake and metabolic syndrome in the elderly in Zhejiang Province in China. Acta Nutrimenta Sinica. 38:299–301. 2016.
21	Ter Borg S, Verlaan S, Hemsworth J, Mijnarends DM, Schols JM, Luiking YC and de Groot LC: Micronutrient intakes and potential inadequacies of community-dwelling older adults: A systematic review. Br J Nutr. 113:1195–1206. 2015.PubMed/NCBI View Article : Google Scholar
22	Wang SS, Lay S, Yu HN and Shen SR: Dietary guidelines for chinese residents (2016): Comments and comparisons. J Zhejiang Univ Sci B. 17:649–656. 2016.PubMed/NCBI View Article : Google Scholar
23	Raszewski G, Chwedorowicz R, Chwedorowicz A and Gustaw Rothenberg K: Homocysteine, antioxidant vitamins and lipids as biomarkers of neurodegeneration in Alzheimer's disease versus non-Alzheimer's dementia. Ann Agric Environ Med. 23:193–196. 2016.PubMed/NCBI View Article : Google Scholar
24	Heart Outcomes Prevention Evaluation Study Investigators. Yusuf S, Dagenais G, Pogue J, Bosch J and Sleight P: Vitamin E supplementation and cardiovascular events in high-risk patients. N Engl J Med. 342:154–160. 2000.PubMed/NCBI View Article : Google Scholar
25	Population Census Office under the State Council of China, National Bureau of Statistics and Department of Population and Employment Statistics: Tabulation On the 2010 Population Census of the People's Republic of China by County. China Statistics Press, 2012.
26	Population Census Office under the State Council of China, National Bureau of Statistics and Department of Population S, Science and Technology Statistics: Tabulation On the 2010 Population Census of the People's Republic of China. China Statistics Press, 2002.