Perspectives of gold nanoparticles and their applications in pancreatic cancer (Review)

  • Authors:
    • Anamaria Magdalena Tomşa
    • Andreea Liana Răchişan
    • Andreea Alexandra Aldea
    • Lorena Ciumărnean
  • View Affiliations

  • Published online on: January 25, 2021     https://doi.org/10.3892/etm.2021.9689
  • Article Number: 258
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Abstract

Nanoparticles (NPs) represent a major point of interest in the scientific field, with an increasing number of studies revealing promising results. Nano‑oncology is a relatively new area of research that continues to expand, revealing new perspectives in both diagnosing and treating cancer. Treating pancreatic cancer (PC) remains a major challenge, with modest positive results, thus an increasing number of studies have focused on this disease. Out of all the NPs that have been used in experimental studies, gold NPs (GNPs) appear to be the most efficient, with little systemic toxicity. This review aims to summarize the latest studies that reveal the effects that GNPs have on PC cells, focusing on different ways in which they can be used to diagnose this disease, to induce apoptosis or cause cytotoxicity in cancer cells. Although literature has limited data concerning this specific topic, the results are promising. However more studies are required until GNPs can be used in clinical practice.
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March-2021
Volume 21 Issue 3

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Tomşa AM, Răchişan AL, Aldea AA and Ciumărnean L: Perspectives of gold nanoparticles and their applications in pancreatic cancer (Review). Exp Ther Med 21: 258, 2021
APA
Tomşa, A.M., Răchişan, A.L., Aldea, A.A., & Ciumărnean, L. (2021). Perspectives of gold nanoparticles and their applications in pancreatic cancer (Review). Experimental and Therapeutic Medicine, 21, 258. https://doi.org/10.3892/etm.2021.9689
MLA
Tomşa, A. M., Răchişan, A. L., Aldea, A. A., Ciumărnean, L."Perspectives of gold nanoparticles and their applications in pancreatic cancer (Review)". Experimental and Therapeutic Medicine 21.3 (2021): 258.
Chicago
Tomşa, A. M., Răchişan, A. L., Aldea, A. A., Ciumărnean, L."Perspectives of gold nanoparticles and their applications in pancreatic cancer (Review)". Experimental and Therapeutic Medicine 21, no. 3 (2021): 258. https://doi.org/10.3892/etm.2021.9689