Open Access

Associations of recurrent lumbar disc herniation after percutaneous endoscopic lumbar discectomy with age, body mass index, modic change, disc degeneration and sacral slope: A quantitative review

  • Authors:
    • Jinlong Zhao
    • Lingfeng Zeng
    • Shuai Zhao
    • Guihong Liang
    • Bangxin Sha
    • Haoyang Fu
    • Weiyi Yang
    • Jun Liu
    • Yuping Zeng
  • View Affiliations

  • Published online on: March 11, 2024     https://doi.org/10.3892/etm.2024.12483
  • Article Number: 195
  • Copyright: © Zhao et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Recurrent lumbar disc herniation (rLDH) seriously affects the quality of life of patients and increases the medical burden. The purpose of the present study was to determine the risk factors for rLDH after percutaneous endoscopic lumbar discectomy (PELD). The PubMed, Cochrane Library and Embase databases were searched for studies on the factors associated with rLDH after PELD. The databases were searched from inception to March 30, 2023. The combined effects of categorical variables and continuous variables were measured using odds ratios (ORs) and weighted mean differences (WMDs), respectively, and their corresponding 95% confidence intervals (CIs) were calculated. RevMan 5.3 software was used for data analysis. A total of 9 case‑control studies were included in this meta‑analysis, comprising 5,446 patients. This study explored a total of 18 potential risk factors for rLDH after PELD; ultimately, 5 factors were associated with the risk of rLDH. Meta‑analysis showed that older age (WMD=6.49, 95% CI: 2.52 to 10.46), greater body mass index (WMD=1.16, 95% CI: 0.69 to 1.62), modic change (OR=2.48, 95% CI: 1.54 to 3.99), Pfirrmann grade ≥4 (OR=2.84, 95% CI: 1.3 to 6.16) and greater sacral slope angle (WMD=3.48, 95% CI: 0.53 to 6.42) were risk factors for rLDH after PELD. The risk factors identified in the present study may enable clinicians to identify high‑risk populations early and to select appropriate surgical procedures to reduce the risk of rLDH. Perioperative interventions targeting the modifiable factors identified in this study may be beneficial for reducing the risk of rLDH.
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May-2024
Volume 27 Issue 5

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Zhao J, Zeng L, Zhao S, Liang G, Sha B, Fu H, Yang W, Liu J and Zeng Y: Associations of recurrent lumbar disc herniation after percutaneous endoscopic lumbar discectomy with age, body mass index, modic change, disc degeneration and sacral slope: A quantitative review. Exp Ther Med 27: 195, 2024.
APA
Zhao, J., Zeng, L., Zhao, S., Liang, G., Sha, B., Fu, H. ... Zeng, Y. (2024). Associations of recurrent lumbar disc herniation after percutaneous endoscopic lumbar discectomy with age, body mass index, modic change, disc degeneration and sacral slope: A quantitative review. Experimental and Therapeutic Medicine, 27, 195. https://doi.org/10.3892/etm.2024.12483
MLA
Zhao, J., Zeng, L., Zhao, S., Liang, G., Sha, B., Fu, H., Yang, W., Liu, J., Zeng, Y."Associations of recurrent lumbar disc herniation after percutaneous endoscopic lumbar discectomy with age, body mass index, modic change, disc degeneration and sacral slope: A quantitative review". Experimental and Therapeutic Medicine 27.5 (2024): 195.
Chicago
Zhao, J., Zeng, L., Zhao, S., Liang, G., Sha, B., Fu, H., Yang, W., Liu, J., Zeng, Y."Associations of recurrent lumbar disc herniation after percutaneous endoscopic lumbar discectomy with age, body mass index, modic change, disc degeneration and sacral slope: A quantitative review". Experimental and Therapeutic Medicine 27, no. 5 (2024): 195. https://doi.org/10.3892/etm.2024.12483