Open Access

In vitro biocompatibility and bioactivity of calcium silicate‑based bioceramics in endodontics (Review)

  • Authors:
    • Wencheng Song
    • Shue Li
    • Qingming Tang
    • Lili Chen
    • Zhenglin Yuan
  • View Affiliations

  • Published online on: May 14, 2021     https://doi.org/10.3892/ijmm.2021.4961
  • Article Number: 128
  • Copyright: © Song et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Calcium silicate‑based bioceramics have been applied in endodontics as advantageous materials for years. In addition to excellent physical and chemical properties, the biocompatibility and bioactivity of calcium silicate‑based bioceramics also serve an important role in endodontics according to previous research reports. Firstly, bioceramics affect cellular behavior of cells such as stem cells, osteoblasts, osteoclasts, fibroblasts and immune cells. On the other hand, cell reaction to bioceramics determines the effect of wound healing and tissue repair following bioceramics implantation. The aim of the present review was to provide an overview of calcium silicate‑based bioceramics currently applied in endodontics, including mineral trioxide aggregate, Bioaggregate, Biodentine and iRoot, focusing on their in vitro biocompatibility and bioactivity. Understanding their underlying mechanism may help to ensure these materials are applied appropriately in endodontics.
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July-2021
Volume 48 Issue 1

Print ISSN: 1107-3756
Online ISSN:1791-244X

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Spandidos Publications style
Song W, Li S, Tang Q, Chen L and Yuan Z: <em>In vitro</em> biocompatibility and bioactivity of calcium silicate‑based bioceramics in endodontics (Review). Int J Mol Med 48: 128, 2021.
APA
Song, W., Li, S., Tang, Q., Chen, L., & Yuan, Z. (2021). <em>In vitro</em> biocompatibility and bioactivity of calcium silicate‑based bioceramics in endodontics (Review). International Journal of Molecular Medicine, 48, 128. https://doi.org/10.3892/ijmm.2021.4961
MLA
Song, W., Li, S., Tang, Q., Chen, L., Yuan, Z."<em>In vitro</em> biocompatibility and bioactivity of calcium silicate‑based bioceramics in endodontics (Review)". International Journal of Molecular Medicine 48.1 (2021): 128.
Chicago
Song, W., Li, S., Tang, Q., Chen, L., Yuan, Z."<em>In vitro</em> biocompatibility and bioactivity of calcium silicate‑based bioceramics in endodontics (Review)". International Journal of Molecular Medicine 48, no. 1 (2021): 128. https://doi.org/10.3892/ijmm.2021.4961