Circular RNA is a popular molecule in tumors of the digestive system (Review)
- Authors:
- Hao‑Ying Wang
- Yu‑Ping Wang
- Xi Zeng
- Ya Zheng
- Qing‑Hong Guo
- Rui Ji
- Yong‑Ning Zhou
-
Affiliations: Department of Gastroenterology, The First Hospital of Lanzhou University, Lanzhou, Gansu 730000, P.R. China - Published online on: April 27, 2020 https://doi.org/10.3892/ijo.2020.5054
- Pages: 21-42
-
Copyright: © Wang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
This article is mentioned in:
Abstract
 |
 |
|
Liu CX, Li X, Nan F, Jiang S, Gao X, Guo SK, Xue W, Cui Y, Dong K, Ding H, et al: Structure and degradation of circular RNAs regulate PKR activation in innate immunity. Cell. 177:865–880.e21. 2019. View Article : Google Scholar : PubMed/NCBI | |
|
Sanger HL, Klotz G, Riesner D, Gross HJ and Kleinschmidt AK: Viroids are single-stranded covalently closed circular RNA molecules existing as highly base-paired rod-like structures. Proc Natl Acad Sci USA. 73:3852–3856. 1976. View Article : Google Scholar : PubMed/NCBI | |
|
Hansen TB, Kjems J and Damgaard CK: Circular RNA and miR-7 in cancer. Cancer Res. 73:5609–5612. 2013. View Article : Google Scholar : PubMed/NCBI | |
|
Memczak S, Jens M, Elefsinioti A, Torti F, Krueger J, Rybak A, Maier L, Mackowiak SD, Gregersen LH, Munschauer M, et al: Circular RNAs are a large class of animal RNAs with regulatory potency. Nature. 495:333–338. 2013. View Article : Google Scholar : PubMed/NCBI | |
|
Zhu K, Hu X, Chen H, Li F, Yin N, Liu AL, Shan K, Qin YW, Huang X, Chang Q, et al: Downregulation of circRNA DMNT3B contributes to diabetic retinal vascular dysfunction through targeting miR-20b-5p and BAMBI. EbioMedicine. 49:341–353. 2019. View Article : Google Scholar : PubMed/NCBI | |
|
Chen Y, Li Z, Zhang M, Wang B, Ye J, Zhang Y, Tang D, Ma D, Jin W, Li X and Wang S: Circ-ASH2L promotes tumor progression by sponging miR-34a to regulate Notch1 in pancreatic ductal adenocarcinoma. J Exp Clin Cancer Res. 38:4662019. View Article : Google Scholar : PubMed/NCBI | |
|
Zuo L, Zhang L, Zu J, Wang Z, Han B, Chen B, Cheng M, Ju M, Li M, Shu G, et al: Circulating circular RNAs as biomarkers for the diagnosis and prediction of outcomes in acute ischemic stroke. Stroke. 51:319–323. 2020. View Article : Google Scholar | |
|
Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA and Jemal A: Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 68:394–424. 2018. View Article : Google Scholar : PubMed/NCBI | |
|
Jeck WR, Sorrentino JA, Wang K, Slevin MK, Burd CE, Liu J, Marzluff WF and Sharpless NE: Circular RNAs are abundant, conserved, and associated with ALU repeats. RNA. 19:141–157. 2013. View Article : Google Scholar : | |
|
Zhang Y, Zhang XO, Chen T, Xiang JF, Yin QF, Xing YH, Zhu S, Yang L and Chen LL: Circular intronic long noncoding RNAs. Mol Cell. 51:792–806. 2013. View Article : Google Scholar : PubMed/NCBI | |
|
Zhang XO, Wang HB, Zhang Y, Lu X, Chen LL and Yang L: Complementary sequence-mediated exon circularization. Cell. 159:134–147. 2014. View Article : Google Scholar : PubMed/NCBI | |
|
Zhang Y, Xue W, Li X, Zhang J, Chen S, Zhang JL, Yang L and Chen LL: The biogenesis of nascent circular RNAs. Cell Rep. 15:611–624. 2016. View Article : Google Scholar : PubMed/NCBI | |
|
Liang D and Wilusz JE: Short intronic repeat sequences facilitate circular RNA production. Genes Dev. 28:2233–2247. 2014. View Article : Google Scholar : PubMed/NCBI | |
|
Conn SJ, Pillman KA, Toubia J, Conn VM, Salmanidis M, Phillips CA, Roslan S, Schreiber AW, Gregory PA and Goodall GJ: The RNA binding protein quaking regulates formation of circRNAs. Cell. 160:1125–34. 2015. View Article : Google Scholar : PubMed/NCBI | |
|
Aktaş T, Avşar Ilık İ, Maticzka D, Bhardwaj V, Pessoa Rodrigues C, Mittler G, Manke T, Backofen R and Akhtar A: DHX9 suppresses RNA processing defects originating from the Alu invasion of the human genome. Nature. 544:115–119. 2017. View Article : Google Scholar | |
|
Ashwal-Fluss R, Meyer M, Pamudurti NR, Ivanov A, Bartok O, Hanan M, Evantal N, Memczak S, Rajewsky N and Kadener S: circRNA biogenesis competes with pre-mRNA splicing. Mol Cell. 56:55–66. 2014. View Article : Google Scholar : PubMed/NCBI | |
|
Tang C, Xie Y, Yu T, Liu N, Wang Z, Woolsey RJ, Tang Y, Zhang X, Qin W, Zhang Y, et al: m6A-dependent biogenesis of circular RNAs in male germ cells. Cell Res. 30:211–228. 2020. View Article : Google Scholar : PubMed/NCBI | |
|
Panda AC, Grammatikakis I, Munk R, Gorospe M and Abdelmohsen K: Emerging roles and context of circular RNAs. Wiley Interdiscip Rev RNA. 8: View Article : Google Scholar : 2017. | |
|
Aufiero S, van den Hoogenhof MMG, Reckman YJ, Beqqali A, van der Made I, Kluin J, Khan MAF, Pinto YM and Creemers EE: Cardiac circRNAs arise mainly from constitutive exons rather than alternatively spliced exons. RNA. 24:815–827. 2018. View Article : Google Scholar : PubMed/NCBI | |
|
Li Z, Huang C, Bao C, Chen L, Lin M, Wang X, Zhong G, Yu B, Hu W, Dai L, et al: Exon-intron circular RNAs regulate transcription in the nucleus. Nat Struct Mol Biol. 22:256–264. 2015. View Article : Google Scholar : PubMed/NCBI | |
|
Abulizi R, Li B and Zhang CG: Circ_0071662, a novel tumor biomarker, suppresses bladder cancer cell proliferation and invasion by sponging miR-146b-3p. Oncol Res. Nov 18–2019.Epub ahead of print. View Article : Google Scholar : PubMed/NCBI | |
|
Zhang XO, Dong R, Zhang Y, Zhang JL, Luo Z, Zhang J, Chen LL and Yang L: Diverse alternative back-splicing and alternative splicing landscape of circular RNAs. Genome Res. 26:1277–1287. 2016. View Article : Google Scholar : PubMed/NCBI | |
|
Ye T, Yang M, Huang D, Wang X, Xue B, Tian N, Xu X, Bao L, Hu H, Lv T and Huang Y: MicroRNA-7 as a potential therapeutic target for aberrant NF-κB-driven distant metastasis of gastric cancer. J Exp Clin Cancer Res. 38:552019. View Article : Google Scholar | |
|
Pan M, Li M, You C, Zhao F, Guo M, Xu H, Li L, Wang L and Dou J: Inhibition of breast cancer growth via miR-7 suppressing ALDH1A3 activity concomitant with decreasing breast cancer stem cell subpopulation. J Cell Physiol. 235:1405–1416. 2020. View Article : Google Scholar | |
|
Liu X, Fu Q, Li S, Liang N, Li F, Li C, Sui C, Dionigi G and Sun H: LncRNA FOXD2-AS1 functions as a competing endogenous RNA to regulate TERT expression by sponging miR-7-5p in thyroid cancer. Front Endocrinol (Lausanne). 10:2072019. View Article : Google Scholar | |
|
Hollensen AK, Andersen S, Hjorth K, Bak RO, Hansen TB, Kjems J, Aagaard L, Damgaard CK and Mikkelsen JG: Enhanced tailored MicroRNA sponge activity of RNA Pol II-transcribed TuD hairpins relative to ectopically expressed ciRS7-derived circRNAs. Mol Ther Nucleic Acids. 13:365–375. 2018. View Article : Google Scholar : PubMed/NCBI | |
|
Zhang Z, Yang T and Xiao J: Circular RNAs: Promising biomarkers for human diseases. EBioMedicine. 34:267–274. 2018. View Article : Google Scholar : PubMed/NCBI | |
|
Du WW, Yang W, Liu E, Yang Z, Dhaliwal P and Yang BB: Foxo3 circular RNA retards cell cycle progression via forming ternary complexes with p21 and CDK2. Nucleic Acids Res. 44:2846–2858. 2016. View Article : Google Scholar : PubMed/NCBI | |
|
Li X, Liu CX, Xue W, Zhang Y, Jiang S, Yin QF, Wei J, Yao RW, Yang L and Chen LL: Coordinated circRNA biogenesis and function with NF90/NF110 in viral infection. Mol Cell. 67:214–227.e7. 2017. View Article : Google Scholar : PubMed/NCBI | |
|
Yang Y, Fan X, Mao M, Song X, Wu P, Zhang Y, Jin Y, Yang Y, Chen LL, Wang Y, et al: Extensive translation of circular RNAs driven by N6-methyladenosine. Cell Res. 27:626–641. 2017. View Article : Google Scholar : PubMed/NCBI | |
|
Legnini I, Di Timoteo G, Rossi F, Morlando M, Briganti F, Sthandier O, Fatica A, Santini T, Andronache A, Wade M, et al: Circ-ZNF609 is a circular RNA that can be translated and functions in myogenesis. Mol Cell. 66:22–37.e9. 2017. View Article : Google Scholar : PubMed/NCBI | |
|
Erratum: Circ-DLG 1 promotes the proliferation of esophageal squamous cell carcinoma [Erratum]. Onco Targets Ther. 12:2552018. View Article : Google Scholar | |
|
Cao S, Chen G, Yan L, Li L and Huang X: Contribution of dysregulated circRNA_100876 to proliferation and metastasis of esophageal squamous cell carcinoma. Onco Targets Ther. 11:7385–7394. 2018. View Article : Google Scholar : PubMed/NCBI | |
|
Xia W, Qiu M, Chen R, Wang S, Leng X, Wang J, Xu Y, Hu J, Dong G, Xu PL and Yin R: Circular RNA has_circ_0067934 is upregulated in esophageal squamous cell carcinoma and promoted proliferation. Sci Rep. 6:355762016. View Article : Google Scholar : PubMed/NCBI | |
|
Zhong R, Chen Z, Mo T, Li Z and Zhang P: Potential role of circPVT1 as a proliferative factor and treatment target in esophageal carcinoma. Cancer Cell Int. 19:2672019. View Article : Google Scholar : PubMed/NCBI | |
|
Wang Q, Zhang Q, Sun H, Tang W, Yang L, Xu Z, Liu Z, Jin H and Cao X: Circ-TTC17 promotes proliferation and migration of esophageal squamous cell carcinoma. Dig Dis Sci. 64:751–758. 2019. View Article : Google Scholar : | |
|
Luo G, Li R and Li Z: CircRNA circFNDC3B promotes esophageal cancer progression via cell proliferation, apoptosis, and migration regulation. Int J Clin Exp Pathol. 11:4188–4196. 2018. | |
|
Song H, Xu D, Shi P, He B, Li Z, Ji Y, Agbeko CK and Wang J: Upregulated circ RNA hsa_circ_0000337 promotes cell proliferation, migration, and invasion of esophageal squamous cell carcinoma. Cancer Manag Res. 11:1997–2006. 2019. View Article : Google Scholar : PubMed/NCBI | |
|
Shi Y, Guo Z, Fang N, Jiang W, Fan Y, He Y, Ma Z and Chen Y: hsa_circ_0006168 sponges miR-100 and regulates mTOR to promote the proliferation, migration and invasion of esophageal squamous cell carcinoma. Biomed Pharmacother. 117:1091512019. View Article : Google Scholar : PubMed/NCBI | |
|
Shi N, Shan B, Gu B, Song Y, Chu H and Qian L: Circular RNA circ-PRKCI functions as a competitive endogenous RNA to regulate AKT3 expression by sponging miR-3680-3p in esophageal squamous cell carcinoma. J Cell Biochem. 120:10021–10030. 2019. View Article : Google Scholar : PubMed/NCBI | |
|
Liu Z, Hu G, Zhao Y, Xiao Z, Yan M and Ren M: Silence of cZNF292 suppresses the growth, migration, and invasion of human esophageal cancer Eca-109 cells via upregulating miR-206. J Cell Biochem. 121:2354–2362. 2020. View Article : Google Scholar | |
|
Wu Y, Zhi L, Zhao Y, Yang L and Cai F: Knockdown of circular RNA UBAP2 inhibits the malignant behaviours of esophageal squamous cell carcinoma by microRNA-422a/Rab10 axis. Clin Exp Pharmacol Physiol. Feb 3–2020.Epub ahead of print. View Article : Google Scholar | |
|
Lan X, Liu X, Sun J, Yuan Q and Li J: CircRAD23B facilitates proliferation and invasion of esophageal cancer cells by sponging miR-5095. Biochem Biophys Res Commun. 516:357–364. 2019. View Article : Google Scholar : PubMed/NCBI | |
|
Zhang Z, Lin W, Gao L, Chen K, Yang C, Zhuang L, Peng S, Kang M and Lin J: Hsa_circ_0004370 promotes esophageal cancer progression through miR-1294/LASP1 pathway. Biosci Rep. 39:pii: BSR20182377. 2019. | |
|
Huang H, Wei L, Qin T, Yang N, Li Z and Xu Z: Circular RNA ciRS-7 triggers the migration and invasion of esophageal squamous cell carcinoma via miR-7/KLF4 and NF-κB signals. Cancer Biol Ther. 20:73–80. 2019. View Article : Google Scholar | |
|
He Y, Mingyan E, Wang C, Liu G, Shi M and Liu S: CircVRK1 regulates tumor progression and radioresistance in esophageal squamous cell carcinoma by regulating miR-624-3p/PTEN/PI3K/AKT signaling pathway. Int J Biol Macromol. 125:116–123. 2019. View Article : Google Scholar | |
|
Zhang Y, Liu H, Li W, Yu J, Li J, Shen Z, Ye G, Qi X and Li G: CircRNA_100269 is downregulated in gastric cancer and suppresses tumor cell growth by targeting miR-630. Aging (Albany NY). 9:1585–1594. 2017. View Article : Google Scholar | |
|
Zhang J, Liu H, Hou L, Wang G, Zhang R, Huang Y, Chen X and Zhu J: Circular RNA_LARP4 inhibits cell proliferation and invasion of gastric cancer by sponging miR-424-5p and regulating LATS1 expression. Mol Cancer. 16:1512017. View Article : Google Scholar : PubMed/NCBI | |
|
Shao Y, Yang Y, Lu R, Xiao B, Ye G and Guo J: Identification of tissue-specific circRNA hsa_circ_0000705 as an indicator for human gastric cancer. Int J Clin Exp Pathol. 10:3151–3156. 2017. | |
|
Shao Y, Chen L, Lu R, Zhang X, Xiao B, Ye G and Guo J: Decreased expression of hsa_circ_0001895 in human gastric cancer and its clinical significances. Tumor Biol. 39:10104283176991252017. View Article : Google Scholar | |
|
Li WH, Song YC, Zhang H, Zhou ZJ, Xie X, Zeng QN, Guo K, Wang T, Xia P and Chang DM: Decreased expression of Hsa_ circ_00001649 in gastric cancer and its clinical significance. Dis Markers. 2017:45876982017. View Article : Google Scholar | |
|
Huang M, He YR, Liang LC, Huang Q and Zhu ZQ: Circular RNA hsa_circ_0000745 may serve as a diagnostic marker for gastric cancer. World J Gastroenterol. 23:6330–6338. 2017. View Article : Google Scholar : PubMed/NCBI | |
|
Chen S, Li T, Zhao Q, Xiao B and Guo J: Using circular RNA hsa_circ_0000190 as a new biomarker in the diagnosis of gastric cancer. Clin Chim Acta. 466:167–171. 2017. View Article : Google Scholar : PubMed/NCBI | |
|
Chen J, Li Y, Zheng Q, Bao C, He J, Chen B, Lyu D, Zheng B, Xu Y, Long Z, et al: Circular RNA profile identifies circPVT1 as a proliferative factor and prognostic marker in gastric cancer. Cancer Lett. 388:208–219. 2017. View Article : Google Scholar | |
|
Zhu Z, Yu Z, Rong Z, Luo Z, Zhang J, Qiu Z and Huang C: The novel GINS4 axis promotes gastric cancer growth and progression by activating Rac1 and CDC42. Theranostics. 9:8294–8311. 2019. View Article : Google Scholar : PubMed/NCBI | |
|
Zhang X, Wang S, Wang H, Cao J, Huang X, Chen Z, Xu P, Sun G, Xu J, Lv J and Xu Z: Circular RNA circNRIP1 acts as a microRNA-149-5p sponge to promote gastric cancer progression via the AKT1/mTOR pathway. Mol Cancer. 18:202019. View Article : Google Scholar : PubMed/NCBI | |
|
Zhang L, Song X, Chen X, Wang Q, Zheng X, Wu C and Jiang J: Circular RNA CircCACTIN promotes gastric cancer progression by sponging MiR-331-3p and regulating TGFBR1 expression. Int J Biol Sci. 15:1091–1103. 2019. View Article : Google Scholar : PubMed/NCBI | |
|
Wang Z, Ma K, Pitts S, Cheng Y, Liu X, Ke X, Kovaka S, Ashktorab H, Smoot DT, Schatz M, et al: Novel circular RNA circNF1 acts as a molecular sponge, promoting gastric cancer by absorbing miR-16. Endocr Relat Cancer. 26:265–277. 2019. View Article : Google Scholar | |
|
Shen F, Liu P, Xu Z, Li N, Yi Z, Tie X, Zhang Y and Gao L: CircRNA_001569 promotes cell proliferation through absorbing miR-145 in gastric cancer. J Biochem. 165:27–36. 2019. View Article : Google Scholar | |
|
Zhang H, Wang X, Huang H, Wang Y, Zhang F and Wang S: Hsa_circ_0067997 promotes the progression of gastric cancer by inhibition of miR-515-5p and activation of X chromosome-linked inhibitor of apoptosis (XIAP). Artif Cells Nanomed Biotechnol. 47:308–318. 2019. View Article : Google Scholar : PubMed/NCBI | |
|
Wei J, Wang J, Gao X and Qi F: Identification of differentially expressed circRNAs and a novel hsa_circ_0000144 that promote tumor growth in gastric cancer. Cancer Cell Int. 19:2682019. View Article : Google Scholar : PubMed/NCBI | |
|
Ouyang Y, Li Y, Huang Y, Li X, Zhu Y, Long Y, Wang Y, Guo X and Gong K: CircRNA circPDSS1 promotes the gastric cancer progression by sponging miR-186-5p and modulating NEK2. J Cell Physiol. 234:10458–10469. 2019. View Article : Google Scholar | |
|
Liang M, Liu Z, Lin H, Shi B, Li M, Chen T, Qin L, Niu Q, Yu G, Jiang H and Zhou X: High-throughput sequencing reveals circular RNA hsa_circ_0000592 as a novel player in the carcinogenesis of gastric carcinoma. Biosci Rep. 39:pii: BSR20181900. 2019. View Article : Google Scholar | |
|
Liang M, Huang G, Liu Z, Wang Q, Yu Z, Liu Z, Lin H, Li M, Zhou X and Zheng Y: Elevated levels of hsa_circ_006100 in gastric cancer promote cell growth and metastasis via miR-195/GPRC5A signalling. Cell Prolif. 52:e126612019. View Article : Google Scholar : PubMed/NCBI | |
|
Huang S, Zhang X, Guan B, Sun P, Hong CT, Peng J, Tang S and Yang J: A novel circular RNA hsa_circ_0008035 contributes to gastric cancer tumorigenesis through targeting the miR-375/YBX1 axis. Am J Transl Res. 11:2455–2462. 2019.PubMed/NCBI | |
|
Wei J, Xu H, Wei W, Wang Z, Zhang Q, De W and Shu Y: circHIPK3 promotes cell proliferation and migration of gastric cancer by sponging miR-107 and regulating BDNF expression. Onco Targets Ther. 13:1613–1624. 2020. View Article : Google Scholar : PubMed/NCBI | |
|
Wang N, Lu K, Qu H, Wang H, Chen Y, Shan T, Ge X, Wei Y, Zhou P and Xia J: CircRBM33 regulates IL-6 to promote gastric cancer progression through targeting miR-149. Biomed Pharmacother. 125:1098762020. View Article : Google Scholar : PubMed/NCBI | |
|
He Y, Wang Y, Liu L, Liu S, Liang L, Chen Y and Zhu Z: Circular RNA circ_0006282 contributes to the progression of gastric cancer by sponging miR-155 to upregulate the expression of FBXO22. Onco Targets Ther. 13:1001–1010. 2020. View Article : Google Scholar : PubMed/NCBI | |
|
Pan H, Pan J, Chen P, Gao J, Guo D, Yang Z, Ji L, Lv H, Guo Y and Xu D: WITHDRAWN: Circular RNA circUBA1 promotes gastric cancer proliferation and metastasis by acting as a competitive endogenous RNA through sponging miR-375 and regulating TEAD4. Cancer Lett. Feb 19–2020.Epub ahead of print. View Article : Google Scholar | |
|
Mo WL, Jiang JT, Zhang L, Lu QC, Li J, Gu WD, Cheng Y and Wang HT: Circular RNA hsa_circ_0000467 promotes the development of gastric cancer by competitively binding to MicroRNA miR-326-3p. Biomed Res Int. 2020:40308262020. View Article : Google Scholar : PubMed/NCBI | |
|
Peng YK, Pu K, Su HX, Zhang J, Zheng Y, Ji R, Guo QH, Wang YP, Guan QL and Zhou YN: Circular RNA hsa_ circ_0010882 promotes the progression of gastric cancer via regulation of the PI3K/Akt/mTOR signaling pathway. Eur Rev Med Pharmacol Sci. 24:1142–1151. 2020.PubMed/NCBI | |
|
Sun B, Sun H, Wang Q, Wang X, Quan J, Dong D and Lun Y: Circular RNA circMAN2B2 promotes growth and migration of gastric cancer cells by down-regulation of miR-145. J Clin Lab Anal. Feb 5–2020.Epub ahead of print. View Article : Google Scholar | |
|
Wei W, Mo X, Yan L, Huang M, Yang Y, Jin Q, Zhong H, Cao W, Wu K, Wu L, et al: Circular RNA profiling reveals that circRNA_104433 regulates cell growth by targeting miR-497-5p in gastric cancer. Cancer Manag Res. 12:15–30. 2020. View Article : Google Scholar : PubMed/NCBI | |
|
Zhao X, Zhong Q, Cheng X, Wang S, Wu R, Leng X and Shao L: miR-449c-5p availability is antagonized by circ-NOTCH1 for MYC-induced NOTCH1 upregulation as well as tumor metastasis and stemness in gastric cancer. J Cell Biochem. Jan;–14. 2020.Epub ahead of print. | |
|
Lu J, Zhang PY, Xie JW, Wang JB, Lin JX, Chen QY, Cao LL, Li P, Zheng CH and Huang CM: Circular RNA hsa_circ_0006848 Related to ribosomal protein L6 Acts as a novel biomarker for early gastric cancer. Dis Markers. 2019:38634582019. View Article : Google Scholar : PubMed/NCBI | |
|
Lu J, Zhang PY, Li P, Xie JW, Wang JB, Lin JX, Chen QY, Cao LL, Huang CM and Zheng CH: Circular RNA hsa_ circ_0001368 suppresses the progression of gastric cancer by regulating miR-6506-5p/FOXO3 axis. Biochem Biophys Res Commun. 512:29–33. 2019. View Article : Google Scholar : PubMed/NCBI | |
|
Liu H, Liu Y, Bian Z, Zhang J, Zhang R, Chen X, Huang Y, Wang Y and Zhu J: Circular RNA YAP1 inhibits the proliferation and invasion of gastric cancer cells by regulating the miR-367-5p/p27 Kip1 axis. Mol Cancer. 17:1512018. View Article : Google Scholar : | |
|
Li Q, Tang H, Hu F and Qin C: Circular RNA SMARCA5 inhibits gastric cancer progression through targeting the miR-346/FBXL2 axis. RSC Adv. 9:18277–18284. 2019. View Article : Google Scholar | |
|
Fang J, Hong H, Xue X, Zhu X, Jiang L, Qin M, Liang H and Gao L: A novel circular RNA, circFAT1(e2), inhibits gastric cancer progression by targeting miR-548g in the cytoplasm and interacting with YBX1 in the nucleus. Cancer Lett. 442:222–232. 2019. View Article : Google Scholar | |
|
Wu L, Liu D and Yang Y: Enhanced expression of circular RNA circ-DCAF6 predicts adverse prognosis and promotes cell progression via sponging miR-1231 and miR-1256 in gastric cancer. Exp Mol Pathol. 110:1042732019. View Article : Google Scholar : PubMed/NCBI | |
|
Ding L, Zhao Y, Dang S, Wang Y, Li X, Yu X, Li Z, Wei J, Liu M and Li G: Circular RNA circ-DONSON facilitates gastric cancer growth and invasion via NURF complex dependent activation o transcription factor SOX4. Mol Cancer. 18:452019. View Article : Google Scholar | |
|
He J, Chen J, Ma B, Jiang L and Zhao G: CircLMTK2 acts as a novel tumor suppressor in gastric cancer. Biosci Rep. 39:pii: BSR20190363. 2019. View Article : Google Scholar | |
|
Lu J, Wang YH, Huang XY, Xie JW, Wang JB, Lin JX, Chen QY, Cao LL, Huang CM, Zheng CH and Li P: circ-CEP85L suppresses the proliferation and invasion of gastric cancer by regulating NFKBIA expression via miR-942-5p. J Cell Physiol. Feb 5–2020.Epub ahead of print. | |
|
Zhang Z, Wu H, Chen Z, Li G and Liu B: Circular RNA ATXN7 promotes the development of gastric cancer through sponging miR-4319 and regulating ENTPD4. Cancer Cell Int. 20:252020. View Article : Google Scholar : PubMed/NCBI | |
|
Deng G, Mou T, He J, Chen D, Lv D, Liu H, Yu J, Wang S and Li G: Circular RNA circRHOBTB3 acts as a sponge for miR-654-3p inhibiting gastric cancer growth. J Exp Clin Cancer Res. 39:12020. View Article : Google Scholar : PubMed/NCBI | |
|
Cai J, Chen Z, Wang J, Wang J, Chen X, Liang L, Huang M, Zhang Z and Zuo X: circHECTD1 facilitates glutaminolysis to promote gastric cancer progression by targeting miR-1256 and activating β-catenin/c-Myc signaling. Cell Death Dis. 10:5762019. View Article : Google Scholar | |
|
Rong D, Lu C, Zhang B, Fu K, Zhao S, Tang W and Cao H: CircPSMC3 suppresses the proliferation and metastasis of gastric cancer by acting as a competitive endogenous RNA through sponging miR-296-5p. Mol Cancer. 18:252019. View Article : Google Scholar : PubMed/NCBI | |
|
Zhou LH, Yang YC, Zhang RY, Wang P, Pang MH and Liang LQ: CircRNA_0023642 promotes migration and invasion of gastric cancer cells by regulating EMT. Eur Rev Med Pharmacol Sci. 22:2297–2303. 2018.PubMed/NCBI | |
|
Xie Y, Shao Y, Sun W, Ye G, Zhang X, Xiao B and Guo J: Downregulated expression of hsa_circ_0074362 in gastric cancer and its potential diagnostic values. Biomark Med. 12:11–20. 2018. View Article : Google Scholar | |
|
Wang L, Shen J and Jiang Y: Circ_0027599/PHDLA1 suppresses gastric cancer progression by sponging miR-101-3p.1. Cell Biosci. 8:582018. View Article : Google Scholar : PubMed/NCBI | |
|
Tian M, Chen R, Li T and Xiao B: Reduced expression of circRNA hsa_circ_0003159 in gastric cancer and its clinical significance. J Clin Lab Anal. 32:2018. View Article : Google Scholar | |
|
Sun HD, Xu ZP, Sun ZQ, Zhu B, Wang Q, Zhou J, Jin H, Zhao A, Tang WW and Cao XF: Down-regulation of circPVRL3 promotes the proliferation and migration of gastric cancer cells. Sci Rep. 8:101112018. View Article : Google Scholar : PubMed/NCBI | |
|
Sun H, Xi P, Sun Z, Wang Q, Zhu B, Zhou J, Jin H, Zheng W, Tang W, Cao H and Cao X: Circ-SFMBT2 promotes the proliferation of gastric cancer cells through sponging miR-182-5p to enhance CREB1 expression. Cancer Manag Res. 10:5725–5734. 2018. View Article : Google Scholar : PubMed/NCBI | |
|
Rong D, Dong C, Fu K, Wang H, Tang W and Cao H: Upregulation of circ_0066444 promotes the proliferation, invasion, and migration of gastric cancer cells. Onco Targets Ther. 11:2753–2761. 2018. View Article : Google Scholar : PubMed/NCBI | |
|
Liu M, Liu KD, Zhang L, Cai J, Yao HW, Bai YK and Zhang ZT: Circ_0009910 regulates growth and metastasis and is associated with poor prognosis in gastric cancer. Eur Rev Med Pharmacol Sci. 22:8248–8256. 2018.PubMed/NCBI | |
|
Zhang H, Zhu L, Bai M, Liu Y, Zhan Y, Deng T, Yang H, Sun W, Wang X, Zhu K, et al: Exosomal circRNA derived from gastric tumor promotes white adipose browning by targeting the miR-133/PRDM16 pathway. Int J Cancer. 144:2501–2515. 2019. View Article : Google Scholar | |
|
Hong Y, Qin H, Li Y, Zhang Y, Zhuang X, Liu L, Lu K, Li L, Deng X, Liu F, et al: FNDC3B circular RNA promotes the migration and invasion of gastric cancer cells via the regulation of E-cadherin and CD44 expression. J Cell Physiol. 234:19895–19910. 2019. View Article : Google Scholar : PubMed/NCBI | |
|
Zhang XY, Xu YY and Chen WY: Upregulation of circular SMAD7 inhibits tumorigenesis of gastric cancer by reversing epithelial-to-mesenchymal transition. Eur Rev Med Pharmacol Sci. 24:1152–1157. 2020.PubMed/NCBI | |
|
Quan J, Dong D, Lun Y, Sun B, Sun H, Wang Q and Yuan G: Circular RNA circHIAT1 inhibits proliferation and epithelial-mesenchymal transition of gastric cancer cell lines through downregulation of miR-21. J Biochem Mol Toxicol. 34:e224582020. View Article : Google Scholar : PubMed/NCBI | |
|
Xue M, Li G, Fang X, Wang L, Jin Y and Zhou Q: hsa_ circ_0081143 promotes cisplatin resistance in gastric cancer by targeting miR-646/CDK6 pathway. Cancer Cell Int. 19:252019. View Article : Google Scholar | |
|
Huang X, Li Z, Zhang Q, Wang W, Li B, Wang L, Xu Z, Zeng A, Zhang X, Zhang X, et al: Circular RNA AKT3 upregulates PIK3R1 to enhance cisplatin resistance in gastric cancer via miR-198 suppression. Mol Cancer. 18:712019. View Article : Google Scholar : PubMed/NCBI | |
|
Huang XX, Zhang Q, Hu H, Jin Y, Zeng AL, Xia YB and Xu L: A novel circular RNA circFN1 enhances cisplatin resistance in gastric cancer via sponging miR-182-5p. J Cell Biochem. Jan 2–2020.Epub ahead of print. View Article : Google Scholar | |
|
Fang Y, Pu N, Zhang L, Wu W and Lou W: Chemoradiotherapy is associated with improved survival for resected pancreatic adenosquamous carcinoma: A retrospective cohort study from the SEER database. Ann Transl Med. 7:5222019. View Article : Google Scholar : PubMed/NCBI | |
|
Yang J, Cong X, Ren M, Sun H, Liu T, Chen G, Wang Q, Li Z, Yu S and Yang Q: Circular RNA hsa_circRNA_0007334 is predicted to promote MMP7 and COL1A1 expression by functioning as a miRNA sponge in pancreatic ductal adenocarcinoma. J Oncol. 2019:76308942019. View Article : Google Scholar : PubMed/NCBI | |
|
Qu S, Hao X, Song W, Niu K, Yang X, Zhang X, Shang R, Wang Q, Li H and Liu Z: Circular RNA circRHOT1 is upregulated and promotes cell proliferation and invasion in pancreatic cancer. Epigenomics. 11:53–63. 2019. View Article : Google Scholar | |
|
Zhu P, Ge N, Liu D, Yang F, Zhang K, Guo J, Liu X, Wang S, Wang G and Sun S: Preliminary investigation of the function of hsa_circ_0006215 in pancreatic cancer. Oncol Lett. 16:603–611. 2018.PubMed/NCBI | |
|
An Y, Cai H, Zhang Y, Liu S, Duan Y, Sun D, Chen X and He X: circZMYM2 competed endogenously with miR-335-5p to regulate JMJD2C in pancreatic cancer. Cell Physiol Biochem. 51:2224–2236. 2018. View Article : Google Scholar : PubMed/NCBI | |
|
Xing C, Ye H, Wang W, Sun M, Zhang J, Zhao Z and Jiang G: Circular RNA ADAM9 facilitates the malignant behaviours of pancreatic cancer by sponging miR-217 and upregulating PRSS3 expression. Artif Cells Nanomed Biotechnol. 47:3920–3928. 2019. View Article : Google Scholar : PubMed/NCBI | |
|
Liu L, Liu FB, Huang M, Xie K, Xie QS, Liu CH, Shen MJ and Huang Q: Circular RNA ciRS-7 promotes the proliferation and metastasis of pancreatic cancer by regulating miR-7-mediated EGFR/STAT3 signaling pathway. Hepatobiliary Pancreat Dis Int. 18:580–586. 2019. View Article : Google Scholar : PubMed/NCBI | |
|
Yang F, Liu DY, Guo JT, Ge N, Zhu P, Liu X, Wang S, Wang GX and Sun SY: Circular RNA circ-LDLRAD3 as a biomarker in diagnosis of pancreatic cancer. World J Gastroenterol. 23:8345–8354. 2017. View Article : Google Scholar | |
|
Li J, Li Z, Jiang P, Peng M, Zhang X, Chen K, Liu H, Bi H, Liu X and Li X: Circular RNA IARS (circ-IARS) secreted by pancreatic cancer cells and located within exosomes regulates endothelial monolayer permeability to promote tumor metastasis. J Exp Clin Cancer Res. 37:1772018. View Article : Google Scholar : PubMed/NCBI | |
|
Ou ZL, Luo Z, Wei W, Liang S, Gao TL and Lu YB: Hypoxia-induced shedding of MICA and HIF1A-mediated immune escape of pancreatic cancer cells from NK cells: Role of circ_0000977/miR-153 axis. RNA Biol. 16:1592–1603. 2019. View Article : Google Scholar : PubMed/NCBI | |
|
Liu Y, Xia L, Dong L, Wang J, Xiao Q, Yu X and Zhu H: CircHIPK3 promotes gemcitabine (GEM) resistance in pancreatic cancer cells by sponging miR-330-5p and targets RASSF1. Cancer Manag Res. 12:921–929. 2020. View Article : Google Scholar : PubMed/NCBI | |
|
Zongyi Y and Xiaowu L: Immunotherapy for hepatocellular carcinoma. Cancer Lett. 470:8–17. 2020. View Article : Google Scholar | |
|
Busato D, Mossenta M, Baboci L, Di Cintio F, Toffoli G and Dal Bo M: Novel immunotherapeutic approaches for hepato-cellular carcinoma treatment. Expert Rev Clin Pharmacol. 12:453–470. 2019. View Article : Google Scholar : PubMed/NCBI | |
|
Yu L, Gong X, Sun L, Zhou Q, Lu B and Zhu L: The circular RNA Cdr1as act as an oncogene in hepatocellular carcinoma through targeting miR-7 expression. PLoS One. 11:e01583472016. View Article : Google Scholar : PubMed/NCBI | |
|
Yao Z, Luo J, Hu K, Lin J, Huang H, Wang Q, Zhang P, Xiong Z, He C, Huang Z, et al: ZKSCAN1 gene and its related circular RNA (circZKSCAN1) both inhibit hepatocellular carcinoma cell growth, migration, and invasion but through different signaling pathways. Mol Oncol. 11:422–437. 2017. View Article : Google Scholar : PubMed/NCBI | |
|
Wang BB, Li JS, Liu YF and Xu Q: MicroRNA-200b suppresses the invasion and migration of hepatocellular carcinoma by downregulating RhoA and circRNA_000839. Tumour Biol. 39:10104283177195772017. View Article : Google Scholar : PubMed/NCBI | |
|
Huang XY, Huang ZL, Xu YH, Zheng Q, Chen Z, Song W, Zhou J, Tang ZY and Huang XY: Comprehensive circular RNA profiling reveals the regulatory role of the circRNA-100338/miR-141-3p pathway in hepatitis B-related hepatocellular carcinoma. Sci Rep. 7:54282017. View Article : Google Scholar : PubMed/NCBI | |
|
Fu L, Yao T, Chen Q, Mo X, Hu Y and Guo J: Screening differential circular RNA expression profiles reveals hsa_circ_0004018 is associated with hepatocellular carcinoma. Oncotarget. 8:58405–58416. 2017. View Article : Google Scholar : PubMed/NCBI | |
|
Zhu Q, Lu G, Luo Z, Gui F, Wu J, Zhang D and Ni Y: CircRNA circ_0067934 promotes tumor growth and metastasis in hepatocellular carcinoma through regulation of miR-1324/FZD5/Wnt/β-catenin axis. Biochem Biophys Res Commun. 497:626–632. 2018. View Article : Google Scholar : PubMed/NCBI | |
|
Zhong L, Wang Y, Cheng Y, Wang W, Lu B, Zhu L and Ma Y: Circular RNA circC3P1 suppresses hepatocellular carcinoma growth and metastasis through miR-4641/PCK1 pathway. Biochem Biophys Res Commun. 499:1044–1049. 2018. View Article : Google Scholar : PubMed/NCBI | |
|
Zhang X, Zhou H, Jing W, Luo P, Qiu S, Liu X, Zhu M, Liang C, Yu M and Tu J: The circular RNA hsa_circ_0001445 regulates the proliferation and migration of hepatocellular carcinoma and may serve as a diagnostic biomarker. Dis Markers. 2018:30734672018. View Article : Google Scholar : PubMed/NCBI | |
|
Zhang X, Xu Y, Qian Z, Zheng W, Wu Q, Chen Y, Zhu G, Liu Y, Bian Z, Xu W, et al: circRNA_104075 stimulates YAP-dependent tumorigenesis through the regulation of HNF4a and may serve as a diagnostic marker in hepatocellular carcinoma. Cell Death Dis. 9:10912018. View Article : Google Scholar : PubMed/NCBI | |
|
Zhang X, Luo P, Jing W, Zhou H, Liang C and Tu J: circSMAD2 inhibits the epithelial-mesenchymal transition by targeting miR-629 in hepatocellular carcinoma. Onco Targets Ther. 11:2853–2863. 2018. View Article : Google Scholar : PubMed/NCBI | |
|
Zhang J, Liu H, Zhang R and Zhu J: Circular RNA SLC3A2 promotes hepatocellular carcinoma growth and invasion by sponging MIR-490-3P and upregulating PPM1F/AKT/GSK3/β-catenin signaling pathway. Gastroenterology. 154(Suppl 1): S11542018. View Article : Google Scholar | |
|
Zhang C, Zhang C, Lin J and Wang H: Circular RNA Hsa_ Circ_0091579 serves as a diagnostic and prognostic marker for hepatocellular carcinoma. Cell Physiol Biochem. 51:290–300. 2018. View Article : Google Scholar | |
|
Yu J, Xu QG, Wang ZG, Yang Y, Zhang L, Ma JZ, Sun SH, Yang F and Zhou WP: Circular RNA cSMARCA5 inhibits growth and metastasis in hepatocellular carcinoma. J Hepatol. 68:1214–1227. 2018. View Article : Google Scholar : PubMed/NCBI | |
|
Wang B, Chen H, Zhang C, Yang T, Zhao Q, Yan Y, Zhang Y and Xu F: Effects of hsa_circRBM23 on hepatocellular carcinoma cell viability and migration as produced by regulating miR-138 expression. Cancer Biother Radiopharm. 33:194–202. 2018. View Article : Google Scholar : PubMed/NCBI | |
|
Meng J, Chen S, Han JX, Qian B, Wang XR, Zhong WL, Qin Y, Zhang H, Gao WF, Lei YY, et al: Twist1 regulates vimentin through Cul2 Circular RNA to promote EMT in hepatocellular carcinoma. Cancer Res. 78:4150–4162. 2018. View Article : Google Scholar : PubMed/NCBI | |
|
Luo Z, Mao X and Cui W: Circular RNA expression and circPTPRM promotes proliferation and migration in hepatocellular carcinoma. Med Oncol. 36:862019. View Article : Google Scholar : PubMed/NCBI | |
|
Li S, Gu H, Huang Y, Peng Q, Zhou R, Yi P, Chen R, Huang Z, Hu X, Huang Y and Tang D: Circular RNA 101368/miR-200a axis modulates the migration of hepatocellular carcinoma through HMGB1/RAGE signaling. Cell Cycle. 17:2349–2359. 2018. View Article : Google Scholar : PubMed/NCBI | |
|
Li MF, Li YH, He YH, Wang Q, Zhang Y, Li XF, Meng XM, Huang C and Li J: Emerging roles of hsa_circ_0005075 targeting miR-431 in the progress of HCC. Biomed Pharmacother. 99:848–858. 2018. View Article : Google Scholar : PubMed/NCBI | |
|
Gong Y, Mao J, Wu D, Wang X, Li L, Zhu L and Song R: Circ-ZEB1.33 promotes the proliferation of human HCC by sponging miR-200a-3p and upregulating CDK6. Cancer Cell Int. 18:1162018. View Article : Google Scholar : PubMed/NCBI | |
|
Chen D, Zhang C, Lin J, Song X and Wang H: Screening differential circular RNA expression profiles reveal that hsa_circ_0128298 is a biomarker in the diagnosis and prognosis of hepatocellular carcinoma. Cancer Manag Res. 10:1275–1283. 2018. View Article : Google Scholar : PubMed/NCBI | |
|
Cai H, Hu B, Ji L, Ruan X and Zheng Z: Hsa_circ_0103809 promotes cell proliferation and inhibits apoptosis in hepatocellular carcinoma by targeting miR-490-5p/SOX2 signaling pathway. Am J Transl Res. 10:1690–1702. 2018.PubMed/NCBI | |
|
Zou H, Xu X, Luo L, Zhang Y, Luo L, Yao Y, Xiang G, Huang X and Wang G: Hsa_circ_0101432 promotes the development of hepatocellular carcinoma (HCC) by adsorbing miR-1258 and miR-622. Cell Cycle. 18:2398–2413. 2019. View Article : Google Scholar : PubMed/NCBI | |
|
Zhu Y, Liu Y, Xiao B, Cai H, Liu M, Ma L, Yin H and Wang F: The circular RNA PVT1/miR-203/HOXD3 pathway promotes the progression of human hepatocellular carcinoma. Biol Open. 8:pii: bio043687. 2019. View Article : Google Scholar : PubMed/NCBI | |
|
Zheng H, Chen T, Li C, Xu C, Ding C, Chen J, Ju S, Zhang Z, Liang Z, Cui Z and Zhao J: A circular RNA hsa_circ_0079929 inhibits tumor growth in hepatocellular carcinoma. Cancer Manag Res. 11:443–454. 2019. View Article : Google Scholar : PubMed/NCBI | |
|
Zhang PF, Wei CY, Huang XY, Peng R, Yang X, Lu JC, Zhang C, Gao C, Cai JB, Gao PT, et al: Circular RNA circTRIM33-12 acts as the sponge of MicroRNA-191 to suppress hepatocellular carcinoma progression. Mol Cancer. 18:1052019. View Article : Google Scholar : PubMed/NCBI | |
|
Zhang J, Chang Y, Xu L and Qin L: Elevated expression of circular RNA circ_0008450 predicts dismal prognosis in hepatocellular carcinoma and regulates cell proliferation, apoptosis, and invasion via sponging miR-548p. J Cell Biochem. 120:9487–9494. 2019. View Article : Google Scholar | |
|
Zhang H, Deng T, Ge S, Liu Y, Bai M, Zhu K, Fan Q, Li J, Ning T, Tian F, et al: Exosome circRNA secreted from adipocytes promotes the growth of hepatocellular carcinoma by targeting deubiquitination-related USP7. Oncogene. 38:2844–2859. 2019. View Article : Google Scholar : | |
|
Zhan W, Liao X, Chen Z, Li L, Tian T, Yu L, Wang W and Hu Q: Circular RNA hsa_circRNA_103809 promoted hepatocellular carcinoma development by regulating miR-377-3p/FGFR1/ERK axis. J Cell Physiol. 235:1733–1745. 2020. View Article : Google Scholar | |
|
Zhai Z, Fu Q, Liu C, Zhang X, Jia P, Xia P, Liu P, Liao S, Qin T and Zhang H: Emerging roles of hsa-circ-0046600 targeting the miR-640/HIF-1α signalling pathway in the progression Of HCC. Onco Targets Ther. 12:9291–9302. 2019. View Article : Google Scholar : | |
|
Yu J, Yang M, Zhou B, Luo J, Zhang Z, Zhang W and Yan Z: CircRNA-104718 acts as competing endogenous RNA and promotes hepatocellular carcinoma progression through microRNA-218-5p/TXNDC5 signaling pathway. Clin Sci (Lond). 133:1487–1503. 2019. View Article : Google Scholar | |
|
Yang W, Liu Y, Gao R, Xiu Z and Sun T: Knockdown of cZNF292 suppressed hypoxic human hepatoma SMMC7721 cell proliferation, vasculogenic mimicry, and radioresistance. Cell Signal. 60:122–135. 2019. View Article : Google Scholar : PubMed/NCBI | |
|
Xu L, Feng X, Hao X, Wang P, Zhang Y, Zheng X, Li L, Ren S, Zhang M and Xu M: CircSETD3 (Hsa_circ_0000567) acts as a sponge for microRNA-421 inhibiting hepatocellular carcinoma growth. J Exp Clin Cancer Res. 38:982019. View Article : Google Scholar : PubMed/NCBI | |
|
Xie B, Zhao Z, Liu Q, Wang X, Ma Z and Li H: CircRNA has_circ_0078710 acts as the sponge of microRNA-31 involved in hepatocellular carcinoma progression. Gene. 683:253–261. 2019. View Article : Google Scholar | |
|
Weng Q, Chen M, Li M, Zheng YF, Shao G, Fan W, Xu XM and Ji J: Global microarray profiling identified hsa_circ_0064428 as a potential immune-associated prognosis biomarker for hepatocellular carcinoma. J Med Genet. 56:32–38. 2019. View Article : Google Scholar | |
|
Wang Z, Zhao Y, Wang Y and Jin C: Circular RNA circHIAT1 inhibits cell growth in hepatocellular carcinoma by regulating miR-3171/PTEN axis. Biomed Pharmacother. 116:1089322019. View Article : Google Scholar : PubMed/NCBI | |
|
Wang X, Wang X, Li W, Zhang Q, Chen J and Chen T: Up-regulation of hsa_circ_0000517 predicts adverse prognosis of hepatocellular carcinoma. Front Oncol. 9:11052019. View Article : Google Scholar : PubMed/NCBI | |
|
Wang L, Long H, Zheng Q, Bo X, Xiao X and Li B: Circular RNA circRHOT1 promotes hepatocellular carcinoma progression by initiation of NR2F6 expression. Mol Cancer. 18:1192019. View Article : Google Scholar : PubMed/NCBI | |
|
Wang G, Liu W, Zou Y, Wang G, Deng Y, Luo J, Zhang Y, Li H, Zhang Q, Yang Y and Chen G: Three isoforms of exosomal circPTGR1 promote hepatocellular carcinoma metastasis via the miR449a-MET pathway. EBioMedicine. 40:432–445. 2019. View Article : Google Scholar : PubMed/NCBI | |
|
Tan A, Li Q and Chen L: CircZFR promotes hepatocellular carcinoma progression through regulating miR-3619-5p/CTNNB1 axis and activating Wnt/β-catenin pathway. Arch Biochem Biophys. 661:196–202. 2019. View Article : Google Scholar | |
|
Sun S, Wang W, Luo X, Li Y, Liu B and Li X, Zhang B, Han S and Li X: Circular RNA circ-ADD3 inhibits hepatocellular carcinoma metastasis through facilitating EZH2 degradation via CDK1-mediated ubiquitination. Am J Cancer Res. 9:1695–1707. 2019.PubMed/NCBI | |
|
Su Y, Xu C, Liu Y, Hu Y and Wu H: Circular RNA hsa_ circ_0001649 inhibits hepatocellular carcinoma progression via multiple miRNAs sponge. Aging (Albany NY). 11:3362–3375. 2019. | |
|
Song C, Li D, Liu H, Sun H, Liu Z, Zhang L and Hu Y: The competing endogenous circular RNA ADAMTS14 suppressed hepatocellular carcinoma progression through regulating microRNA-572/regulator of calcineurin 1. J Cell Physiol. 234:2460–2470. 2019. View Article : Google Scholar | |
|
Qiu L, Huang Y, Li Z, Dong X, Chen G, Xu H, Zeng Y, Cai Z, Liu X and Liu J: Circular RNA profiling identifies circADAMTS13 as a miR-484 sponge which suppresses cell proliferation in hepatocellular carcinoma. Mol Oncol. 13:441–455. 2019. | |
|
Pan H, Tang L, Jiang H, Li X, Wang R, Gao J and Li Q: Enhanced expression of circ_0000267 in hepatocellular carcinoma indicates poor prognosis and facilitates cell progression by sponging miR-646. J Cell Biochem. 120:11350–11357. 2019. View Article : Google Scholar | |
|
Navarro A: Twist1 activated circRNA-10720 is a new player in hepatocellular carcinoma metastasis. Transl Cancer Res. 8(S2): S135–S140. 2019. View Article : Google Scholar | |
|
Ma Y, Zhang C, Zhang B, Yu H and Yu Q: circRNA of AR-suppressed PABPC1 91 bp enhances the cytotoxicity of natural killer cells against hepatocellular carcinoma via upregulating UL16 binding protein 1. Oncol Lett. 17:388–397. 2019.PubMed/NCBI | |
|
Luo Y, Fu Y, Huang R, Gao M, Liu F, Gui R and Nie X: CircRNA_101505 sensitizes hepatocellular carcinoma cells to cisplatin by sponging miR-103 and promotes oxidored-nitro domain-containing protein 1 expression. Cell Death Discov. 5:1212019. View Article : Google Scholar : PubMed/NCBI | |
|
Lin T, Dai Y, Guo X, Chen W, Zhao J, Cao L and Wu Z: Silencing of hsa_circ_0008450 represses hepatocellular carcinoma progression through regulation of microRNA-214-3p/EZH2 axis. Cancer Manag Res. 11:9133–9143. 2019. View Article : Google Scholar : PubMed/NCBI | |
|
Liang WC, Wong CW, Liang PP, Shi M, Cao Y, Rao ST, Tsui SK, Waye MM, Zhang Q, Fu WM and Zhang JF: Translation of the circular RNA circβ-catenin promotes liver cancer cell growth through activation of the Wnt pathway. Genome Biol. 20:842019. View Article : Google Scholar | |
|
Li Z, Hu Y, Zeng Q, Wang H, Yan J, Li H and Yu Z: Circular RNA MYLK promotes hepatocellular carcinoma progression by increasing Rab23 expression by sponging miR-362-3p. Cancer Cell Int. 19:2112019. View Article : Google Scholar : PubMed/NCBI | |
|
Li X and Shen M: Circular RNA hsa_circ_103809 suppresses hepatocellular carcinoma proliferation and invasion by sponging miR-620. Eur Rev Med Pharmacol Sci. 23:555–566. 2019.PubMed/NCBI | |
|
Kou P, Zhang C, Lin J and Wang H: Circular RNA hsa_ circ_0078602 may have potential as a prognostic biomarker for patients with hepatocellular carcinoma. Oncol Lett. 17:2091–2098. 2019.PubMed/NCBI | |
|
Ji L, Xu J, Lin Z, Mao Q, Zhang B and Cai X: Stabilization of UBQLN1 by circRNA_104797 mediates acquired sorafenib resistance in hepatocellular carcinoma. J Hepatol. 70:E71–E73. 2019. View Article : Google Scholar | |
|
Guan Z, Tan J, Gao W, Li X, Yang Y, Li X, Li Y and Wang Q: Circular RNA hsa_circ_0016788 regulates hepatocellular carcinoma tumorigenesis through miR-486/CDK4 pathway. J Cell Physiol. 234:500–508. 2018. View Article : Google Scholar : PubMed/NCBI | |
|
Fu HW, Lin X, Zhu YX, Lan X, Kuang Y, Wang YZ, Ke ZG, Yuan T and Chen P: Circ-IGF1R has pro-proliferative and anti-apoptotic effects in HCC by activating the PI3K/AKT pathway. Gene. 716:1440312019. View Article : Google Scholar : PubMed/NCBI | |
|
Fang Z, Fan R, Lu Y, Sun Y, Zhao C, Liu L and Liu X: Circular RNA hsa_circ_0002124 promotes hepatocellular carcinoma cell proliferation through the MAPK pathway. Transl Cancer Res. 8:367–378. 2019. View Article : Google Scholar | |
|
Chen Z, Zuo X, Pu L, Zhang Y, Han G, Zhang L, Wu J and Wang X: circLARP4 induces cellular senescence through regulating miR-761/RUNX3/p53/p21 signaling in hepatocellular carcinoma. Cancer Sci. 110:568–581. 2019. View Article : Google Scholar : | |
|
Chen Q, Chen Z, Cao S, Guo B, Chen Y, Feng Z, Wang J, Guo G, Chen X and Huang X: Role of CircRNAs_100395 in proliferation and metastases of liver cancer. Med Sci Monit. 25:6181–6192. 2019. View Article : Google Scholar : PubMed/NCBI | |
|
Chen H, Liu S, Li M, Huang P and Li X: circ_0003418 inhibits tumorigenesis and cisplatin chemoresistance through Wnt/β-catenin pathway in hepatocellular carcinoma. Onco Targets Ther. 12:9539–9549. 2019. View Article : Google Scholar : | |
|
Cao S, Wang G, Wang J, Li C and Zhang L: Hsa_circ_101280 promotes hepatocellular carcinoma by regulating miR-375/JAK2. Immunol Cell Biol. 97:218–228. 2019. View Article : Google Scholar | |
|
Zhao M, Dong G, Meng Q, Lin S and Li X: Circ-HOMER1 enhances the inhibition of miR-1322 on CXCL6 to regulate the growth and aggressiveness of hepatocellular carcinoma cells. J Cell Biochem. Feb 9–2020.Epub ahead of print. View Article : Google Scholar | |
|
Yu Q, Dai J and Shu M: Hsa_circ_0003645 shows an oncogenic role by sponging microRNA-1299 in hepatocellular carcinoma cells. J Clin Lab Anal. Feb 28–2020.Epub ahead of print. View Article : Google Scholar | |
|
Xiao Y, Liu G, Sun Y, Gao Y, Ouyang X, Chang C, Gong L and Yeh S: Targeting the estrogen receptor alpha (ERα)-mediated circ-SMG1.72/miR-141-3p/Gelsolin signaling to better suppress the HCC cell invasion. Oncogene. 39:2493–2508. 2020. View Article : Google Scholar : PubMed/NCBI | |
|
Wei X, Zheng W, Tian P, He Y, Liu H, Peng M, Li X and Liu X: Oncogenic hsa_circ_0091581 promotes the malignancy of HCC cell through blocking miR-526b from degrading c-MYC mRNA. Cell Cycle. 19:817–824. 2020. View Article : Google Scholar : PubMed/NCBI | |
|
Pu J, Wang J, Li W, Lu Y, Wu X, Long X, Luo C and Wei H: hsa_circ_0000092 promotes hepatocellular carcinoma progression through up-regulating HN1 expression by binding to microRNA-338-3p. J Cell Mol Med. Feb 20–2020.Epub ahead of print. View Article : Google Scholar | |
|
Liu D, Kang H, Gao M, Jin L, Zhang F, Chen D, Li M and Xiao L: Exosome-transmitted circ_MMP2 promotes hepatocellular carcinoma metastasis by upregulating MMP2. Mol Oncol. Jan 14–2020.Epub ahead of print. View Article : Google Scholar | |
|
Liu B, Yang G, Wang X, Liu J, Lu Z, Wang Q, Xu B, Liu Z and Li J: CircBACH1 (hsa_circ_0061395) promotes hepatocellular carcinoma growth by regulating p27 repression via HuR. J Cell Physiol. Jan 31–2020.Epub ahead of print. | |
|
Li Z, Liu Y, Yan J, Zeng Q, Hu Y, Wang H, Li H, Li J and Yu Z: Circular RNA hsa_circ_0056836 functions an oncogenic gene in hepatocellular carcinoma through modulating miR-766-3p/FOSL2 axis. Aging (Albany NY). 12:2485–2497. 2020. View Article : Google Scholar | |
|
Gao J, Dai C, Yu X, Yin X-B and Zhou F: Circ-TCF4.85 silencing inhibits cancer progression through microRNA-486-5p-targeted inhibition of ABCF2 in hepatocellular carcinoma. Mol Oncol. 14:447–461. 2020. View Article : Google Scholar : | |
|
Ding Z, Guo L, Deng Z and Li P: Circ-PRMT5 enhances the proliferation, migration and glycolysis of hepatoma cells by targeting miR-188-5p/HK2 axis. Ann Hepatol. Jan 27–2020.Epub ahead of print. View Article : Google Scholar : PubMed/NCBI | |
|
Chen W, Quan Y, Fan S, Wang H, Liang J, Huang L, Chen L, Liu Q, He P and Ye Y: Exosome-transmitted circular RNA hsa_ circ_0051443 suppresses hepatocellular carcinoma progression. Cancer Lett. 475:119–128. 2020. View Article : Google Scholar : PubMed/NCBI | |
|
Yao Z, Xu R, Yuan L, Xu M, Zhuang H, Li Y, Zhang Y and Lin N: Circ_0001955 facilitates hepatocellular carcinoma (HCC) tumorigenesis by sponging miR-516a-5p to release TRAF6 and MAPK11. Cell Death Dis. 10:945. 2019. View Article : Google Scholar : PubMed/NCBI | |
|
Chen L, Kong R, Wu C, Wang S, Liu Z and Liu S, Li S, Chen T, Mao C and Liu S: Circ-MALAT1 functions as Both an mRNA translation brake and a microRNA sponge to promote self-renewal of hepatocellular cancer stem cells. Adv Sci (Weinh). 7:19009492019. View Article : Google Scholar | |
|
Sun P, Fan X, Hu X, Fu X, Wei Q and Zang Y: circPCNX and pecanex promote hepatocellular carcinoma cell viability by inhibiting miR-506. Cancer Manag Res. 11:10957–10967. 2019. View Article : Google Scholar | |
|
Liu Z, Yu Y, Huang Z, Kong Y, Hu X, Xiao W, Quan J and Fan X: CircRNA-5692 inhibits the progression of hepatocellular carcinoma by sponging miR-328-5p to enhance DAB2IP expression. Cell Death Dis. 10:9002019. View Article : Google Scholar : PubMed/NCBI | |
|
Fu Y, Cai L, Lei X and Wang D: Circular RNA ABCB10 promotes hepatocellular carcinoma progression by increasing HMG20A expression by sponging miR-670-3p. Cancer Cell Int. 19:3382019. View Article : Google Scholar : | |
|
Hu ZQ, Zhou SL, Li J, Zhou ZJ, Wang PC, Xin HY, Mao L, Luo CB, Yu SY, Huang XW, et al: Circular RNA sequencing identifies CircASAP1 as a key regulator in hepatocellular carcinoma metastasis. Hepatology. Dec 15–2019.Epub ahead of print. View Article : Google Scholar : PubMed/NCBI | |
|
Xu S, Zhan M, Jiang C, He M, Yang L, Shen H, Huang S, Huang X, Lin R, Shi Y, et al: Genome-wide CRISPR screen identifies ELP5 as a determinant of gemcitabine sensitivity in gallbladder cancer. Nat Commun. 10:54922019. View Article : Google Scholar : PubMed/NCBI | |
|
Wang S, Zhang Y, Cai Q, Ma M, Jin LY, Weng M, Zhou D, Tang Z, Wang JD and Quan Z: Circular RNA FOXP1 promotes tumor progression and Warburg effect in gallbladder cancer by regulating PKLR expression. Mol Cancer. 18:1452019. View Article : Google Scholar : PubMed/NCBI | |
|
Kai D, Yannian L, Yitian C, Dinghao G, Xin Z and Wu J: Circular RNA HIPK3 promotes gallbladder cancer cell growth by sponging microRNA-124. Biochem Biophys Res Commun. 503:863–869. 2018. View Article : Google Scholar : PubMed/NCBI | |
|
Huang X, He M, Huang S, Lin R, Zhan M, Yang D, Shen H, Xu S, Cheng W, Yu J, et al: Circular RNA circERBB2 promotes gallbladder cancer progression by regulating PA2G4-dependent rDNA transcription. Mol Cancer. 18:1662019. View Article : Google Scholar : PubMed/NCBI | |
|
Ahnen DJ and Patel SG: Cost-effectiveness and national effects of initiating colorectal cancer screening for average-risk persons at age 45 years instead of 50 years. Gastroenterology. 157:1691–1692. 2019. View Article : Google Scholar : PubMed/NCBI | |
|
Wang X, Zhang Y, Huang L, Zhang J, Pan F, Li B, Yan Y, Jia B, Liu H, Li S and Zheng W: Decreased expression of hsa_ circ_001988 in colorectal cancer and its clinical significances. Int J Clin Exp Pathol. 8:16020–16025. 2015. | |
|
Xie H, Ren X, Xin S, Lan X, Lu G, Lin Y, Yang SS, Zeng ZC, Liao WT, Ding YQ and Liang L: Emerging roles of circRNA_001569 targeting miR-145 in the proliferation and invasion of colorectal cancer. Oncotarget. 7:26680–26691. 2016. View Article : Google Scholar : PubMed/NCBI | |
|
Guo JN, Li J, Zhu CL, Feng WT, Shao JX, Wan L, Huang MD and He JD: Comprehensive profile of differentially expressed circular RNAs reveals that hsa_circ_0000069 is upregulated and promotes cell proliferation, migration, and invasion in colorectal cancer. Onco Targets Ther. 9:7451–7458. 2016. View Article : Google Scholar : PubMed/NCBI | |
|
Zhuo F, Lin H, Chen Z, Huang Z and Hu J: The expression profile and clinical significance of circRNA0003906 in colorectal cancer. Onco Targets Ther. 10:5187–5193. 2017. View Article : Google Scholar : PubMed/NCBI | |
|
Zhu M, Xu Y, Chen Y and Yan F: Circular BANP, an upregulated circular RNA that modulates cell proliferation in colorectal cancer. Biomed Pharmacother. 88:138–144. 2017. View Article : Google Scholar : PubMed/NCBI | |
|
Zhang XL, Xu LL and Wang F: Hsa_circ_0020397 regulates colorectal cancer cell viability, apoptosis and invasion by promoting the expression of the miR-138 targets TERT and PD-L1. Cell Biol Int. 41:1056–1064. 2017. View Article : Google Scholar : PubMed/NCBI | |
|
Zhang R, Xu J, Zhao J and Wang X: Silencing of hsa_ circ_0007534 suppresses proliferation and induces apoptosis in colorectal cancer cells. Eur Rev Med Pharmacol Sci. 22:118–126. 2018.PubMed/NCBI | |
|
Zeng K, Chen X, Xu M, Liu X, Hu X, Xu T, Sun H, Pan Y, He B and Wang S: CircHIPK3 promotes colorectal cancer growth and metastasis by sponging miR-7. Cell Death Dis. 9:4172018. View Article : Google Scholar : PubMed/NCBI | |
|
Yuan Y, Liu W, Zhang Y, Zhang Y and Sun S: CircRNA circ_0026344 as a prognostic biomarker suppresses colorectal cancer progression via microRNA-21 and microRNA-31. Biochem Biophys Res Commun. 503:870–875. 2018. View Article : Google Scholar : PubMed/NCBI | |
|
Wu L, Xia J, Yang J, Shi Y, Xia H, Xiang X and Yu X: Circ-ZNF609 promotes migration of colorectal cancer by inhibiting Gli1 expression via microRNA-150. J BUON. 23:1343–1349. 2018.PubMed/NCBI | |
|
Li XN, Wang ZJ, Ye CX, Zhao BC, Li ZL and Yang Y: RNA sequencing reveals the expression profiles of circRNA and indicates that circDDX17 acts as a tumor suppressor in colorectal cancer. J Exp Clin Cancer Res. 37:3252018. View Article : Google Scholar : PubMed/NCBI | |
|
Li X, Wang J, Zhang C, Lin C, Zhang J, Zhang W, Zhang W, Lu Y, Zheng L and Li X: Circular RNA circITGA7 inhibits colorectal cancer growth and metastasis by modulating the Ras pathway and upregulating transcription of its host gene ITGA7. J Pathol. 246:166–179. 2018. View Article : Google Scholar : PubMed/NCBI | |
|
Jin Y, Yu LL, Zhang B, Liu CF and Chen Y: Circular RNA hsa_circ_0000523 regulates the proliferation and apoptosis of colorectal cancer cells as miRNA sponge. Braz J Med Biol Res. 51:e78112018. View Article : Google Scholar : PubMed/NCBI | |
|
He JH, Li YG, Han ZP, Zhou JB, Chen WM, Lv YB, He ML, Zuo JD and Zheng L: The CircRNA-ACAP2/Hsa-miR-21-5p/Tiam1 regulatory feedback circuit affects the proliferation, migration, and invasion of colon cancer SW480 cells. Cell Physiol Biochem. 49:1539–1550. 2018. View Article : Google Scholar | |
|
Fang G, Ye BL, Hu BR, Ruan XJ and Shi YX: CircRNA_100290 promotes colorectal cancer progression through miR-516b-induced downregulation of FZD4 expression and Wnt/β-catenin signaling. Biochem Biophys Res Commun. 504:184–189. 2018. View Article : Google Scholar : PubMed/NCBI | |
|
Bian L, Zhi X, Ma L, Zhang J, Chen P, Sun S, Li J, Sun Y and Qin J: Hsa_circRNA_103809 regulated the cell proliferation and migration in colorectal cancer via miR-532-3p/FOXO4 axis. Biochem Biophys Res Commun. 505:346–352. 2018. View Article : Google Scholar : PubMed/NCBI | |
|
Geng Y, Zheng X, Hu W, Wang Q, Xu Y, He W, Wu C, Zhu D, Wu C and Jiang J: Hsa_circ_0009361 acts as the sponge of miR-582 to suppress colorectal cancer progression by regulating APC2 expression. Clin Sci (Lond). 133:1197–1213. 2019. View Article : Google Scholar | |
|
Jin C, Wang A, Liu L, Wang G and Li G: Hsa_circ_0136666 promotes the proliferation and invasion of colorectal cancer through miR-136/SH2B1 axis. J Cell Physiol. 234:7247–7256. 2019. View Article : Google Scholar | |
|
Li H, Jin X, Liu B, Zhang P, Chen W and Li Q: CircRNA CBL.11 suppresses cell proliferation by sponging miR-6778-5p in colorectal cancer. BMC Cancer. 19:8262019. View Article : Google Scholar : PubMed/NCBI | |
|
Li R, Wu B, Xia J, Ye L and Yang X: Circular RNA hsa_ circRNA_102958 promotes tumorigenesis of colorectal cancer via miR-585/CDC25B axis. Cancer Manag Res. 11:6887–6893. 2019. View Article : Google Scholar : | |
|
Li XN, Wang ZJ, Ye CX, Zhao BC, Huang XX and Yang L: Circular RNA circVAPA is up-regulated and exerts oncogenic properties by sponging miR-101 in colorectal cancer. Biomed Pharmacother. 112:1086112019. View Article : Google Scholar : PubMed/NCBI | |
|
Li Y, Li C, Xu R, Wang Y, Li D and Zhang B: A novel circFMN2 promotes tumor proliferation in CRC by regulating the miR-1182/hTERT signaling pathways. Clin Sci (Lond). 133:2463–2479. 2019. View Article : Google Scholar | |
|
Lu C, Jiang W, Hui B, Rong D, Fu K, Dong C, Tang W and Cao H: The circ_0021977/miR-10b-5p/P21 and P53 regulatory axis suppresses proliferation, migration, and invasion in colorectal cancer. J Cell Physiol. 235:2273–2285. 2020. View Article : Google Scholar | |
|
Min L, Wang H and Zeng Y: CircRNA_104916 regulates migration, apoptosis and epithelial-mesenchymal transition in colon cancer cells. Front Biosci (Landmark Ed). 24:819–832. 2019. View Article : Google Scholar | |
|
Pan B, Qin J, Liu X, He B, Wang X, Pan Y, Sun H, Xu T, Xu M, Chen X, et al: Identification of serum exosomal hsa-circ-0004771 as a novel diagnostic biomarker of colorectal cancer. Front Genet. 10:10362019. View Article : Google Scholar | |
|
Shen T, Cheng X, Liu X, Xia C, Zhang H, Pan D, Zhang X and Li Y: Circ_0026344 restrains metastasis of human colorectal cancer cells via miR-183. Artif Cells Nanomed Biotechnol. 47:4038–4045. 2019. View Article : Google Scholar : PubMed/NCBI | |
|
Tian J, Xi X, Wang J, Yu J, Huang Q, Ma R, Zhang X, Li H and Wang L: CircRNA hsa_circ_0004585 as a potential biomarker for colorectal cancer. Cancer Manag Res. 11:5413–5423. 2019. View Article : Google Scholar : PubMed/NCBI | |
|
Yang F, Fang E, Mei H, Chen Y, Li H, Li D, Song H, Wang J, Hong M, Xiao W, et al: Cis-acting circ-CTNNB1 promotes β-catenin signaling and cancer progression via DDX3-mediated transactivation of YY1. Cancer Res. 79:557–571. 2019. View Article : Google Scholar | |
|
Yang G, Zhang T, Ye J, Yang J, Chen C, Cai S and Ma J: Circ-ITGA7 sponges miR-3187-3p to upregulate ASXL1, suppressing colorectal cancer proliferation. Cancer Manag Res. 11:6499–6509. 2019. View Article : Google Scholar : PubMed/NCBI | |
|
Zhang J, Liu H, Zhao P, Zhou H and Mao T: Has_circ_0055625 from circRNA profile increases colon cancer cell growth by sponging miR-106b-5p. J Cell Biochem. 120:3027–3037. 2019. View Article : Google Scholar | |
|
Zhang X, Zhao Y, Kong P, Han M and Li B: Expression of circZNF609 is down-regulated in colorectal cancer tissue and promotes apoptosis in colorectal cancer cells by upregulating p53. Med Sci Monit. 25:5977–5985. 2019. View Article : Google Scholar : PubMed/NCBI | |
|
Zhou C, Liu HS, Wang FW, Hu T, Liang ZX, Lan N, He XW, Zheng XB, Wu XJ, Xie D, et al: circCAMSAP1 promotes tumor growth in colorectal cancer via the miR-328-5p/E2F1 axis. Mol Ther. 28:914–928. 2020. View Article : Google Scholar : PubMed/NCBI | |
|
Zhu CL, Sha X, Wang Y, Li J, Zhang MY, Guo ZY, Sun SA and He JD: Circular RNA hsa_circ_0007142 Is upregulated and targets miR-103a-2-5p in colorectal cancer. J Oncol. 2019:98368192019. View Article : Google Scholar : PubMed/NCBI | |
|
Chen HY, Li XN, Ye CX, Chen ZL and Wang ZJ: Circular RNA circHUWE1 is upregulated and promotes cell proliferation, migration and invasion in colorectal cancer by sponging miR-486. Onco Targets Ther. 13:423–434. 2020. View Article : Google Scholar : PubMed/NCBI | |
|
Li W, Xu Y, Wang X, Cao G, Bu W, Wang X, Fang Z, Xu Y, Dong M and Tao Q: circCCT3 modulates vascular endothelial growth factor A and Wnt signaling to enhance colorectal cancer metastasis through sponging miR-613. DNA Cell Biol. 39:118–125. 2020. View Article : Google Scholar | |
|
Pei FL, Cao MZ and Li YF: Circ_0000218 plays a carcinogenic role in colorectal cancer progression by regulating miR-139-3p/RAB1A axis. J Biochem. 167:55–65. 2020. View Article : Google Scholar : PubMed/NCBI | |
|
Ren C, Zhang Z, Wang S, Zhu W, Zheng P and Wang W: Circular RNA hsa_circ_0001178 facilitates the invasion and metastasis of colorectal cancer through upregulating ZEB1 via sponging multiple miRNAs. Biol Chem. 401:487–496. 2020. View Article : Google Scholar | |
|
Wang X, Zhang H, Yang H, Bai M, Ning T, Deng T, Liu R, Fan Q, Zhu K, Li J, et al: Exosome-delivered circRNA promotes glycolysis to induce chemoresistance through the miR-122-PKM2 axis in colorectal cancer. Mol Oncol. 14:539–555. 2020. View Article : Google Scholar : PubMed/NCBI | |
|
Yang B, Du K, Yang C, Xiang L, Xu Y, Cao C, Zhang J and Liu W: CircPRMT5 circular RNA promotes proliferation of colorectal cancer through sponging miR-377 to induce E2F3 expression. J Cell Mol Med. 24:3431–3437. 2020. View Article : Google Scholar : PubMed/NCBI | |
|
Yang H, Li X, Meng Q, Sun H, Wu S, Hu W, Liu G, Li X, Yang Y and Chen R: CircPTK2 (hsa_circ_0005273) as a novel therapeutic target for metastatic colorectal cancer. Mol Cancer. 19:132020. View Article : Google Scholar : PubMed/NCBI | |
|
Yang L, Sun H, Liu X, Chen J, Tian Z, Xu J, Xiang B and Qin B: Circular RNA hsa_circ_0004277 contributes to malignant phenotype of colorectal cancer by sponging miR-512-5p to upregulate the expression of PTMA. J Cell Physiol. Jan 21–2020.Epub ahead of print. View Article : Google Scholar | |
|
Zhao H, Chen S and Fu Q: Exosomes from CD133+ cells carrying circ-ABCC1 mediate cell stemness and metastasis in colorectal cancer. J Cell Biochem. 121:3286–3297. 2020. View Article : Google Scholar : PubMed/NCBI | |
|
Joensuu H, Vehtari A, Riihimäki J, Nishida T, Steigen SE, Brabec P, Plank L, Nilsson B, Cirilli C, Braconi C, et al: Risk of recurrence of gastrointestinal stromal tumour after surgery: An analysis of pooled population-based cohorts. Lancet Oncol. 13:265–274. 2012. View Article : Google Scholar | |
|
Jia N, Tong H, Zhang Y, Katayama H, Wang Y, Lu W, Zhang S and Wang J: CeRNA expression profiling identifies KIT-Related circRNA-miRNA-mRNA networks in gastrointestinal stromal tumour. Front Genet. 10:8252019. View Article : Google Scholar : PubMed/NCBI | |
|
Anastasiadou E, Jacob LS and Slack FJ: Non-coding RNA networks in cancer. Nat Rev Cancer. 18:5–18. 2018. View Article : Google Scholar | |
|
Lewis BP, Burge CB and Bartel DP: Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell. 120:15–20. 2005. View Article : Google Scholar : PubMed/NCBI | |
|
Xu B, Yang T, Wang Z, Zhang Y, Liu S and Shen M: CircRNA CDR1as/miR-7 signals promote tumor growth of osteosarcoma with a potential therapeutic and diagnostic value. Cancer Manag Res. 10:4871–4880. 2018. View Article : Google Scholar : PubMed/NCBI | |
|
Pan H, Li T, Jiang Y, Pan C, Ding Y, Huang Z, Yu H and Kong D: Overexpression of circular RNA ciRS-7 abrogates the tumor suppressive effect of miR-7 on gastric cancer via PTEN/PI3K/AKT signaling pathway. J Cell Biochem. 119:440–446. 2018. View Article : Google Scholar | |
|
Kabir TD, Ganda C, Brown RM, Beveridge DJ, Richardson KL, Chaturvedi V, Candy P, Epis M, Wintle L, Kalinowski F, et al: A microRNA-7/growth arrest specific 6/TYRO3 axis regulates the growth and invasiveness of sorafenib-resistant cells in human hepatocellular carcinoma. Hepatology. 67:216–231. 2018. View Article : Google Scholar | |
|
Li H, Fan J, Zhao Y, Zhang X, Dai B, Zhan J, Yin Z, Nie X, Fu XD, Chen C and Wang DW: Nuclear miR-320 mediates diabetes-induced cardiac dysfunction by activating transcription of fatty acid metabolic genes to cause lipotoxicity in the heart. Circ Res. 125:1106–1120. 2019. View Article : Google Scholar : PubMed/NCBI | |
|
Yuan H, Chen Z, Bai S, Wei H, Wang Y, Ji R, Guo Q, Li Q, Ye Y, Wu J, et al: Molecular mechanisms of lncRNA SMARCC2/miR-551b-3p/TMPRSS4 axis in gastric cancer. Cancer Lett. 418:84–96. 2018. View Article : Google Scholar : PubMed/NCBI | |
|
Ding J, Zhao J, Huan L, Liu Y, Qiao Y, Wang Z, Chen Z, Huang S, Zhao Y and He X: Inflammation-induced LINC00665 increases the malignancy through activating PKR/NF-κB pathway in hepatocellular carcinoma. Hepatology. Feb 21–2020.Epub ahead of print. View Article : Google Scholar |
