1
|
Lindemann A, Takahashi H, Patel AA, Osman
AA and Myers JN: Targeting the DNA damage response in OSCC with
TP53 mutations. J Dent Res. 97:635–644. 2018. View Article : Google Scholar
|
2
|
Jiang Y, Li T, Wu Y, Xu H, Xie C, Dong Y,
Zhong L, Wang Z, Zhao H, Zhou Y, et al: GPR39 overexpression in
OSCC promotes YAP-sustained malignant progression. J Dent Res.
99:949–958. 2020. View Article : Google Scholar
|
3
|
Chen Y, Shao Z, Jiang E, Zhou X, Wang L,
Wang H, Luo X, Chen Q, Liu K and Shang Z: CCL21/CCR7 interaction
promotes EMT and enhances the stemness of OSCC via a JAK2/STAT3
signaling pathway. J Cell Physiol. 235:5995–6009. 2020. View Article : Google Scholar
|
4
|
Yang Z, Liang X, Fu Y, Liu Y, Zheng L, Liu
F, Li T, Yin X, Qiao X and Xu X: Identification of AUNIP as a
candidate diagnostic and prognostic biomarker for oral squamous
cell carcinoma. EBioMedicine. 47:44–57. 2019. View Article : Google Scholar
|
5
|
Quail DF and Joyce JA: Microenvironmental
regulation of tumor progression and metastasis. Nat Med.
19:1423–1437. 2013. View
Article : Google Scholar
|
6
|
Li Z, Liu FY and Kirkwood KL: The
p38/MKP-1 signaling axis in oral cancer: Impact of tumor-associated
macrophages. Oral Oncol. 103:1045912020. View Article : Google Scholar
|
7
|
Yoshihara K, Shahmoradgoli M, Martínez E,
Vegesna R, Kim H, Torres-Garcia W, Treviño V, Shen H, Laird PW,
Levine DA, et al: Inferring tumour purity and stromal and immune
cell admixture from expression data. Nat Commun. 4:26122013.
View Article : Google Scholar
|
8
|
Peddareddigari VG, Wang D and Dubois RN:
The tumor microenvironment in colorectal carcinogenesis. Cancer
Microenviron. 3:149–166. 2010. View Article : Google Scholar
|
9
|
Bhome R, Mellone M, Emo K, Thomas GJ,
Sayan AE and Mirnezami AH: The colorectal cancer microenvironment:
Strategies for studying the role of cancer-associated fibroblasts.
Methods Mol Biol. 1765:87–98. 2018. View Article : Google Scholar
|
10
|
Udagawa T and Wood M: Tumor-stromal cell
interactions and opportunities for therapeutic intervention. Curr
Opin Pharmacol. 10:369–374. 2010. View Article : Google Scholar
|
11
|
Potter SM, Dwyer RM, Hartmann MC, Khan S,
Boyle MP, Curran CE and Kerin MJ: Influence of stromal-epithelial
interactions on breast cancer in vitro and in vivo. Breast Cancer
Res Treat. 131:401–411. 2012. View Article : Google Scholar
|
12
|
O'Malley G, Treacy O, Lynch K, Naicker SD,
Leonard NA, Lohan P, Dunne PD, Ritter T, Egan LJ and Ryan AE:
Stromal cell PD-L1 inhibits CD8+ T-cell antitumor immune
responses and promotes colon cancer. Cancer Immunol Res.
6:1426–1441. 2018. View Article : Google Scholar
|
13
|
Trivanović D, Krstić J, Jauković A,
Bugarski D and Santibanez JF: Mesenchymal stromal cell engagement
in cancer cell epithelial to mesenchymal transition. Dev Dyn.
247:359–367. 2018. View Article : Google Scholar
|
14
|
Patel SG and Shah JP: TNM staging of
cancers of the head and neck: Striving for uniformity among
diversity. CA Cancer J Clin. 55:242–258. 2005. View Article : Google Scholar
|
15
|
Spiro RH, Guillamondegui O Jr, Paulino AF
and Huvos AG: Pattern of invasion and margin assessment in patients
with oral tongue cancer. Head Neck. 21:408–413. 1999. View Article : Google Scholar
|
16
|
Hussein MR and Cullen K: Molecular
biomarkers in HNSCC: Prognostic and therapeutic implications.
Expert Rev Anticancer Ther. 1:116–24. 2001. View Article : Google Scholar
|
17
|
Takabatake K, Kawai H, Omori H, Qiusheng
S, Oo MW, Sukegawa S, Nakano K, Tsujigiwa H and Nagatsuka H: Impact
of the stroma on the biological characteristics of the parenchyma
in oral squamous cell carcinoma. Int J Mol Sci. 21:77142020.
View Article : Google Scholar
|
18
|
Zhang X, Junior CR, Liu M, Li F, D'Silva
NJ and Kirkwood KL: Oral squamous carcinoma cells secrete RANKL
directly supporting osteolytic bone loss. Oral Oncol. 49:119–128.
2013. View Article : Google Scholar
|
19
|
An YZ, Cho E, Ling J and Zhang X: The
Axin2-snail axis promotes bone invasion by activating
cancer-associated fibroblasts in oral squamous cell carcinoma. BMC
Cancer. 20:9872020. View Article : Google Scholar
|
20
|
Jögi A, Vaapil M, Johansson M and Påhlman
S: Cancer cell differentiation heterogeneity and aggressive
behavior in solid tumors. Ups J Med Sci. 117:217–224. 2012.
View Article : Google Scholar
|
21
|
Watanabe M, Ohnishi Y, Wato M, Tanaka A
and Kakudo K: SOX4 expression is closely associated with
differentiation and lymph node metastasis in oral squamous cell
carcinoma. Med Mol Morphol. 47:150–155. 2014. View Article : Google Scholar
|
22
|
Sun Z, Hu S, Luo Q, Ye D, Hu D and Chen F:
Overexpression of SENP3 in oral squamous cell carcinoma and its
association with differentiation. Oncol Rep. 29:1701–1706. 2013.
View Article : Google Scholar
|
23
|
Kang MK, Chen W and Park NH: Regulation of
epithelial cell proliferation, differentiation, and plasticity by
grainyhead-like 2 during oral carcinogenesis. Crit Rev Oncog.
23:201–217. 2018. View Article : Google Scholar
|
24
|
Feng X, Zheng Z, Wang Y, Song G, Wang L,
Zhang Z, Zhao J, Wang Q and Lun L: Elevated RUNX1 is a prognostic
biomarker for human head and neck squamous cell carcinoma. Exp Biol
Med (Maywood). 246:538–546. 2021. View Article : Google Scholar
|
25
|
Gkouveris I, Nikitakis N, Avgoustidis D,
Karanikou M, Rassidakis G and Sklavounou A: ERK1/2, JNK and STAT3
activation and correlation with tumor differentiation in oral SCC.
Histol Histopathol. 32:1065–1076. 2017.
|
26
|
Sapkota D, Bruland O, Parajuli H, Osman
TA, The MT, Johannessen AC and Costea DE: S100A16 promotes
differentiation and contributes to a less aggressive tumor
phenotype in oral squamous cell carcinoma. BMC Cancer. 15:6312015.
View Article : Google Scholar
|
27
|
Kim B, Nam S, Lim JH and Lim JS: NDRG2
expression decreases tumor-induced osteoclast differentiation by
down-regulating ICAM1 in breast cancer cells. Biomol Ther (Seoul).
24:9–18. 2016. View Article : Google Scholar
|
28
|
Astarci E, Sade A, Cimen I, Savaş B and
Banerjee S: The NF-κB target genes ICAM-1 and VCAM-1 are
differentially regulated during spontaneous differentiation of
Caco-2 cells. FEBS J. 279:2966–2986. 2012. View Article : Google Scholar
|
29
|
Wang QL, Li BH, Liu B, Liu YB, Liu YP,
Miao SB, Han Y, Wen JK and Han M: Polymorphisms of the ICAM-1 exon
6 (E469K) are associated with differentiation of colorectal cancer.
J Exp Clin Cancer Res. 28:1392009. View Article : Google Scholar
|
30
|
Revu S, Wu J, Henkel M, Rittenhouse N,
Menk A, Delgoffe GM, Poholek AC and McGeachy MJ: IL-23 and IL-1β
drive human Th17 cell differentiation and metabolic reprogramming
in absence of CD28 costimulation. Cell Rep. 22:2642–2653. 2018.
View Article : Google Scholar
|
31
|
Xue G, Jin G, Fang J and Lu Y: IL-4
together with IL-1β induces antitumor Th9 cell differentiation in
the absence of TGF-β signaling. Nat Commun. 10:13762019. View Article : Google Scholar
|
32
|
Albrecht M, Doroszewicz J, Gillen S, Gomes
I, Wilhelm B, Stief T and Aumüller G: Proliferation of prostate
cancer cells and activity of neutral endopeptidase is regulated by
bombesin and IL-1beta with IL-1beta acting as a modulator of
cellular differentiation. Prostate. 58:82–94. 2004. View Article : Google Scholar
|
33
|
Szemes M, Melegh Z, Bellamy J, Greenhough
A, Kollareddy M, Catchpoole D and Malik K: A wnt-BMP4 signaling
axis induces MSX and NOTCH proteins and promotes growth suppression
and differentiation in neuroblastoma. Cells. 9:7832020. View Article : Google Scholar
|
34
|
Catalano V, Dentice M, Ambrosio R, Luongo
C, Carollo R, Benfante A, Todaro M, Stassi G and Salvatore D:
Activated thyroid hormone promotes differentiation and
chemotherapeutic sensitization of colorectal cancer stem cells by
regulating wnt and BMP4 signaling. Cancer Res. 76:1237–1244. 2016.
View Article : Google Scholar
|
35
|
Zhang L, Sun H, Zhao F, Lu P, Ge C, Li H,
Hou H, Yan M, Chen T, Jiang G, et al: BMP4 administration induces
differentiation of CD133+ hepatic cancer stem cells,
blocking their contributions to hepatocellular carcinoma. Cancer
Res. 72:4276–4285. 2012. View Article : Google Scholar
|
36
|
Fell SM, Li S, Wallis K, Kock A, Surova O,
Rraklli V, Höfig CS, Li W, Mittag J, Henriksson MA, et al:
Neuroblast differentiation during development and in neuroblastoma
requires KIF1Bβ-mediated transport of TRKA. Genes Dev.
31:1036–1053. 2017. View Article : Google Scholar
|
37
|
Condello S, Caccamo D, Currò M, Ferlazzo
N, Parisi G and Ientile R: Transglutaminase 2 and NF-kappaB
interplay during NGF-induced differentiation of neuroblastoma
cells. Brain Res. 1207:1–8. 2008. View Article : Google Scholar
|
38
|
Louhichi T, Saad H, Dhiab MB, Ziadi S and
Trimeche M: Stromal CD10 expression in breast cancer correlates
with tumor invasion and cancer stem cell phenotype. BMC Cancer.
18:492018. View Article : Google Scholar
|
39
|
Moriyama T, Ohuchida K, Mizumoto K, Cui L,
Ikenaga N, Sato N and Tanaka M: Enhanced cell migration and
invasion of CD133+ pancreatic cancer cells cocultured with
pancreatic stromal cells. Cancer. 116:3357–3368. 2010. View Article : Google Scholar
|
40
|
Liu Y, Pan J, Pan X, Wu L, Bian J, Lin Z,
Xue M, Su T, Lai S, Chen F, et al: Klotho-mediated targeting of
CCL2 suppresses the induction of colorectal cancer progression by
stromal cell senescent microenvironments. Mol Oncol. 13:2460–2475.
2019. View Article : Google Scholar
|
41
|
Kadaba R, Birke H, Wang J, Hooper S, Andl
CD, Di Maggio F, Soylu E, Ghallab M, Bor D, Froeling FE, et al:
Imbalance of desmoplastic stromal cell numbers drives aggressive
cancer processes. J Pathol. 230:107–117. 2013. View Article : Google Scholar
|
42
|
Sun LP, Xu K, Cui J, Yuan DY, Zou B, Li J,
Liu JL, Li KY, Meng Z and Zhang B: Cancer-associated
fibroblast-derived exosomal miR-382-5p promotes the migration and
invasion of oral squamous cell carcinoma. Oncol Rep. 42:1319–1328.
2019.
|
43
|
Ding L, Ren J, Zhang D, Li Y, Huang X, Hu
Q, Wang H, Song Y, Ni Y and Hou Y: A novel stromal lncRNA signature
reprograms fibroblasts to promote the growth of oral squamous cell
carcinoma via LncRNA-CAF/interleukin-33. Carcinogenesis.
39:397–406. 2018. View Article : Google Scholar
|
44
|
Wang Y, Jing Y, Ding L, Zhang X, Song Y,
Chen S, Zhao X, Huang X, Pu Y, Wang Z, et al: Epiregulin reprograms
cancer-associated fibroblasts and facilitates oral squamous cell
carcinoma invasion via JAK2-STAT3 pathway. J Exp Clin Cancer Res.
38:2742019. View Article : Google Scholar
|
45
|
Herrero AB, García-Gómez A, Garayoa M,
Corchete LA, Hernández JM, San Miguel J and Gutierrez NC: Effects
of IL-8 up-regulation on cell survival and osteoclastogenesis in
multiple myeloma. Am J Pathol. 186:2171–2182. 2016. View Article : Google Scholar
|
46
|
Cioni B, Nevedomskaya E, Melis MH, van
Burgsteden J, Stelloo S, Hodel E, Spinozzi D, de Jong J, van der
Poel H, de Boer JP, et al: Loss of androgen receptor signaling in
prostate cancer-associated fibroblasts (CAFs) promotes CCL2- and
CXCL8-mediated cancer cell migration. Mol Oncol. 12:1308–1323.
2018. View Article : Google Scholar
|
47
|
New J, Arnold L, Ananth M, Alvi S,
Thornton M, Werner L, Tawfik O, Dai H, Shnayder Y, Kakarala K, et
al: Secretory autophagy in cancer-associated fibroblasts promotes
head and neck cancer progression and offers a novel therapeutic
target. Cancer Res. 77:6679–6691. 2017. View Article : Google Scholar
|
48
|
Giri J, Das R, Nylen E, Chinnadurai R and
Galipeau J: CCL2 and CXCL12 derived from mesenchymal stromal cells
cooperatively polarize IL-10+ tissue macrophages to mitigate gut
injury. Cell Rep. 30:1923–1934.e4. 2020. View Article : Google Scholar
|
49
|
Yao M, Fang W, Smart C, Hu Q, Huang S,
Alvarez N, Fields P and Cheng N: CCR2 chemokine receptors enhance
growth and cell-cycle progression of breast cancer cells through
SRC and PKC activation. Mol Cancer Res. 17:604–617. 2019.
View Article : Google Scholar
|
50
|
Sun X, Glynn DJ, Hodson LJ, Huo C, Britt
K, Thompson EW, Woolford L, Evdokiou A, Pollard JW, Robertson SA
and Ingman WV: CCL2-driven inflammation increases mammary gland
stromal density and cancer susceptibility in a transgenic mouse
model. Breast Cancer Res. 19:42017. View Article : Google Scholar
|
51
|
Tsuyada A, Chow A, Wu J, Somlo G, Chu P,
Loera S, Luu T, Li AX, Wu X, Ye W, et al: CCL2 mediates cross-talk
between cancer cells and stromal fibroblasts that regulates breast
cancer stem cells. Cancer Res. 72:2768–2779. 2012. View Article : Google Scholar
|
52
|
Acharyya S, Oskarsson T, Vanharanta S,
Malladi S, Kim J, Morris PG, Manova-Todorova K, Leversha M, Hogg N,
Seshan VE, et al: A CXCL1 paracrine network links cancer
chemoresistance and metastasis. Cell. 150:165–178. 2012. View Article : Google Scholar
|
53
|
Miyake M, Hori S, Morizawa Y, Tatsumi Y,
Nakai Y, Anai S, Torimoto K, Aoki K, Tanaka N, Shimada K, et al:
CXCL1-mediated interaction of cancer cells with tumor-associated
macrophages and cancer-associated fibroblasts promotes tumor
progression in human bladder cancer. Neoplasia. 18:636–646. 2016.
View Article : Google Scholar
|
54
|
Park GY, Pathak HB, Godwin AK and Kwon Y:
Epithelial-stromal communication via CXCL1-CXCR2 interaction
stimulates growth of ovarian cancer cells through p38 activation.
Cell Oncol (Dordr). 44:77–92. 2021. View Article : Google Scholar
|
55
|
Zou A, Lambert D, Yeh H, Yasukawa K,
Behbod F, Fan F and Cheng N: Elevated CXCL1 expression in breast
cancer stroma predicts poor prognosis and is inversely associated
with expression of TGF-β signaling proteins. BMC Cancer.
14:7812014. View Article : Google Scholar
|
56
|
Wei LY, Lee JJ, Yeh CY, Yang CJ, Kok SH,
Ko JY, Tsai FC and Chia JS: Reciprocal activation of
cancer-associated fibroblasts and oral squamous carcinoma cells
through CXCL1. Oral Oncol. 88:115–123. 2019. View Article : Google Scholar
|
57
|
Baba Y, Nosho K, Shima K, Meyerhardt JA,
Chan AT, Engelman JA, Cantley LC, Loda M, Giovannucci E, Fuchs CS
and Ogino S: Prognostic significance of AMP-activated protein
kinase expression and modifying effect of MAPK3/1 in colorectal
cancer. Br J Cancer. 103:1025–1033. 2010. View Article : Google Scholar
|
58
|
Lin J, Cao S, Wang Y, Hu Y, Liu H, Li J,
Chen J, Li P, Liu J, Wang Q and Zheng L: Long non-coding RNA
UBE2CP3 enhances HCC cell secretion of VEGFA and promotes
angiogenesis by activating ERK1/2/HIF-1α/VEGFA signaling in
hepatocellular carcinoma. J Exp Clin Cancer Res. 37:1132018.
View Article : Google Scholar
|
59
|
Yan Z, Ohuchida K, Fei S, Zheng B, Guan W,
Feng H, Kibe S, Ando Y, Koikawa K, Abe T, et al: Inhibition of
ERK1/2 in cancer-associated pancreatic stellate cells suppresses
cancer-stromal interaction and metastasis. J Exp Clin Cancer Res.
38:2212019. View Article : Google Scholar
|
60
|
García-Carracedo D, Cai Y, Qiu W, Saeki K,
Friedman RA, Lee A, Li Y, Goldberg EM, Stratikopoulos EE, Parsons
R, et al: PIK3CA and p53 mutations promote 4NQO-initated head and
neck tumor progression and metastasis in mice. Mol Cancer Res.
18:822–834. 2020. View Article : Google Scholar
|
61
|
Cohen Y, Goldenberg-Cohen N, Shalmon B,
Shani T, Oren S, Amariglio N, Dratviman-Storobinsky O,
Shnaiderman-Shapiro A, Yahalom R, Kaplan I and Hirshberg A:
Mutational analysis of PTEN/PIK3CA/AKT pathway in oral squamous
cell carcinoma. Oral Oncol. 47:946–950. 2011. View Article : Google Scholar
|