Open Access

Mechanism of exosomes in the tumor microenvironment in the abscopal effect (Review)

  • Authors:
    • Guicheng Kuang
    • Zirui Wang
    • Chengyu Luo
    • Jingyan Luo
    • Jing Wang
  • View Affiliations

  • Published online on: November 7, 2022     https://doi.org/10.3892/ijo.2022.5450
  • Article Number: 2
  • Copyright: © Kuang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Previously, the abscopal effect, which is an antitumor therapeutic effect on untreated tumor locations elsewhere in the body as a result of treatment of the targeted region, was rarely reported, and its mechanism remains unknown. Increasing evidence has shown that the immune system is implicated in the abscopal effect, and that combining immunotherapy and radiation can assist to improve its frequency. Understanding how different types of cells and cell‑derived exosomes cause the abscopal effect in the tumor microenvironment (TME) is crucial to increasing the clinical occurrence of the abscopal effect in the TME.
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January-2023
Volume 62 Issue 1

Print ISSN: 1019-6439
Online ISSN:1791-2423

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Copy and paste a formatted citation
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Spandidos Publications style
Kuang G, Wang Z, Luo C, Luo J and Wang J: Mechanism of exosomes in the tumor microenvironment in the abscopal effect (Review). Int J Oncol 62: 2, 2023.
APA
Kuang, G., Wang, Z., Luo, C., Luo, J., & Wang, J. (2023). Mechanism of exosomes in the tumor microenvironment in the abscopal effect (Review). International Journal of Oncology, 62, 2. https://doi.org/10.3892/ijo.2022.5450
MLA
Kuang, G., Wang, Z., Luo, C., Luo, J., Wang, J."Mechanism of exosomes in the tumor microenvironment in the abscopal effect (Review)". International Journal of Oncology 62.1 (2023): 2.
Chicago
Kuang, G., Wang, Z., Luo, C., Luo, J., Wang, J."Mechanism of exosomes in the tumor microenvironment in the abscopal effect (Review)". International Journal of Oncology 62, no. 1 (2023): 2. https://doi.org/10.3892/ijo.2022.5450