CD99-positive soft tissue sarcoma with chromosomal translocation between 1 and 16 and inversion of chromosome 5
- Authors:
- Masahiko Kanamori
- Kayo Suzuki
- Taketoshi Yasuda
- Takeshi Hori
View Affiliations
Affiliations: Department of Human Science 1, University of Toyama, Toyama City, Toyama 930-0194, Japan, Department of Orthopaedics, University of Toyama, Toyama City, Toyama 930-0194, Japan
- Published online on: March 9, 2012 https://doi.org/10.3892/ol.2012.641
-
Pages:
1213-1215
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Abstract
In this study, we report the cytogenetic analysis of a 31-year‑old male with a rare translocation between chromosomes 1 and 16 and inversion of chromosome 5 in CD99-positive soft tissue sarcoma of the thigh, which metastasized to the lung. Histologically, the tumor showed ovoid or short-spindle atypical cells with positivities of CD99, vimentin and bcl-2. Cytogenetically, all 20 analyzed cells showed the clonal aberrations add(1)(q23), t(1;16)(p21;p11.2), inv(5)(q11.2;q15). This finding adds to the new karyotype spectrum of CD99‑positive soft tissue sarcomas.
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