Management of a patient with colon cancer and rotor syndrome: A case report

  • Authors:
    • Deniz Arslan
    • Fatma Avcı
    • Alparslan Merdin
    • Seyda Gunduz
    • Haslan Senol Coskun
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  • Published online on: December 19, 2013     https://doi.org/10.3892/ol.2013.1766
  • Pages: 797-798
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Abstract

Rotor Syndrome (RS) is a rare disease that is autosomal recessive and characterized by asymptomatic jaundice, conjugated hyperbilirubinemia and coproporphyria. RS occurs as a result of a complete lack or partial defect of organic anion transporter polypeptides (OATPs) on the basolateral surface of hepatocytes. OATPs facilitate the excretion of bilirubin and organic anions from the liver to the bile. To the best of our knowledge, there is no information in the literature relating to the treatment of a patient with colon cancer and RS. The present study aimed to discuss the systematic chemotherapy that is used and the effects on a 45‑year‑old patient who had RS with asymptomatic jaundice and was diagnosed with colon adenocarcinoma following surgery. The patient was administered oxaliplatin in combination with capecitabine. The patient's biluribin level increased after one week. Capecitabine treatment was interrupted and the patient was administered oxaliplatin monotherapy. No significant toxicity was observed during that period. At the latest follow-up the patient did not exhibit any progression.
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2014-March
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Spandidos Publications style
Arslan D, Avcı F, Merdin A, Gunduz S and Coskun HS: Management of a patient with colon cancer and rotor syndrome: A case report. Oncol Lett 7: 797-798, 2014.
APA
Arslan, D., Avcı, F., Merdin, A., Gunduz, S., & Coskun, H.S. (2014). Management of a patient with colon cancer and rotor syndrome: A case report. Oncology Letters, 7, 797-798. https://doi.org/10.3892/ol.2013.1766
MLA
Arslan, D., Avcı, F., Merdin, A., Gunduz, S., Coskun, H. S."Management of a patient with colon cancer and rotor syndrome: A case report". Oncology Letters 7.3 (2014): 797-798.
Chicago
Arslan, D., Avcı, F., Merdin, A., Gunduz, S., Coskun, H. S."Management of a patient with colon cancer and rotor syndrome: A case report". Oncology Letters 7, no. 3 (2014): 797-798. https://doi.org/10.3892/ol.2013.1766