Undifferentiated embryonal sarcoma of the liver mistaken for hepatic abscess in an adult

Xie,Zi‑Ying; Li,Li‑Ping; Wu,Wei‑Jing; Sun,Da‑Yong; Zhou,Mei‑Hua; Zhao,Ya‑Gang

doi:10.3892/ol.2014.2235

Undifferentiated embryonal sarcoma of the liver mistaken for hepatic abscess in an adult

Authors:
- Zi‑Ying Xie
- Li‑Ping Li
- Wei‑Jing Wu
- Da‑Yong Sun
- Mei‑Hua Zhou
- Ya‑Gang Zhao
View Affiliations

Affiliations: Department of Gastroenterology, Guangzhou General Hospital of Guangzhou Military Command, Guangzhou, Guangdong 510010, P.R. China, Department of Respiratory, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian 362000, P.R. China
Published online on: June 11, 2014 https://doi.org/10.3892/ol.2014.2235
Pages: 1184-1186

Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )

Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )

Cited By (CrossRef): 0 citations Loading Articles...

Abstract

Undifferentiated embryonal sarcoma of the liver (UESL) predominantly occurs in children under the age of 10 years, and ~90% of cases occur in children <15 years old. Patients may complain of abdominal pain, fever or other symptoms. No significant decrease has been identified in the hepatic function or elevation of α-fetoprotein, which differentiates UESL from primary carcinomas of the liver. In the present study, a rare and misdiagnosed case of an UESL arising in a male, which was mistaken for a hepatic abscess and retrospectively re‑diagnosed, is reported. This case was misdiagnosed as a hepatic abscess initially, and it was diagnosed as UESL subsequent to performing tests, including a type‑B ultrasonic scan and computed tomography (CT), and evaluating pathological findings. The rapid recurrence of the tumor in this patient was identified by CT, and this is associated with the malignancy of the disease. Currently, patients with UESL have a poor prognosis as there is not a successful treatment strategy. The present study analyzes the course of diagnosis and potential treatment for the disease.

View Figures

View References

1	Lenze F, Birkfellner T, Lenz P, et al: Undifferentiated embryonal sarcoma of the liver in adults. Cancer. 112:2274–2282. 2008.
2	Stocker JT and Ishak KG: Undifferentiated (embryonal) sarcoma of the liver: report of 31 cases. Cancer. 42:336–348. 1978.
3	Nishio J, Iwasaki H, Sakashita N, et al: Undifferentiated (embryonal) sarcoma of the liver in middle-aged adults: smooth muscle differentiation determined by immunohistochemistry and electron microscopy. Hum Pathol. 34:246–252. 2003.
4	Jia C, Zhao W, Dai C, et al: Undifferentiated embryonal sarcoma of the liver in a middle-aged adult with systemic lupus erythematosus. World J Surg Oncol. 11:2442013.
5	Lyu S, Shi X, Liang Y, et al: Diagnosis and therapy of primary undifferentiated embryonal sarcoma of the liver. Chin Med J (Engl). 127:1585–1587. 2014.
6	Kim M, Tireno B and Slanetz P: Undifferentiated embryonal sarcoma of the liver. Am J Roentgenol. 190:W261–W262. 2008.
7	Li XW, Gong SJ, Song WH, et al: Undifferentiated liver embryonal sarcoma in adults: a report of four cases and literature review. World J Gastroenterol. 16:4725–4732. 2010.
8	Stocker JT and Ishak KG: Undifferentiated (embryonal) sarcoma of the liver: report of 31 cases. Cancer. 42:336–348. 1978.
9	Lack EE, Schloo BL, Azumi N, et al: Undifferentiated (embryonal) sarcoma of the liver. Clinical and pathologic study of 16 cases with emphasis on immunohistochemical features. Am J Surg Pathol. 15:1–16. 1991.
10	Vick DJ, Goodman ZD, Deavers MT, et al: Ciliated hepatic foregut cyst: a study of six cases and review of the literature. Am J Surg Pathol. 23:671–677. 1999.
11	Faraj W, Mukherji D, El Majzoub N, et al: Primary undifferentiated embryonal sarcoma of the liver mistaken for hydatid disease. World J Surg Oncol. 8:582010.
12	Kelly MJ, Martin L, Alonso M and Altura RA: Liver transplant for relapsed undifferentiated embryonal sarcoma in a young child. J Pediatr Surg. 44:e1–e3. 2009.
13	Dower NA, Smith LJ, Lees G, et al: Experience with aggressive therapy in three children with unresectable malignant liver tumors. Med Pediatr Oncol. 34:132–135. 2000.
14	Li XW, Gong SJ, Song WH, et al: Undifferentiated liver embryonal sarcoma in adults: a report of four cases and literature review. World J Gastroenterol. 16:4725–4732. 2010.
15	Dai CL, Xu F, Shu H, et al: Undifferentiated (embryonal) sarcoma of liver in adult: a case report. World J Gastroenterol. 11:926–929. 2005.
16	Yang L, Chen LB, Xiao J and Han P: Clinical features and spiral computed tomography analysis of undifferentiated embryonic liver sarcoma in adults. J Dig Dis. 10:305–309. 2009.
17	Kalra N, Vyas S, Jyoti Das P, et al: Undifferentiated embryonal sarcoma of liver in an adult masquerading as complicated hydatid cyst. Ann Hepatol. 10:81–83. 2011.
18	Charfi S, Ayadi L, Toumi N, et al: Cystic undifferentiated sarcoma of liver in children: a pitfall diagnosis in endemic hydatidosis areas. J Pediatr Surg. 43:E1–E4. 2008.
19	Aggarwal S, Guleria S, Dinda AK, et al: Embryonal sarcoma of the liver mimicking a hydatid cyst in an adult. Trop Gastroenterol. 22:141–142. 2001.