Clear cell sarcoma of the right lumbar region: A case report and review of the literature

Yang,Xue-Li; Lu,San-Jun; Xue,Jie; Wu,Yan-Fen; Shi,Jun-Ling

doi:10.3892/ol.2014.2372

Clear cell sarcoma of the right lumbar region: A case report and review of the literature

Authors:
- Xue-Li Yang
- San-Jun Lu
- Jie Xue
- Yan-Fen Wu
- Jun-Ling Shi
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Affiliations: Department of Pathology, The First Hospital of Handan City, Handan, Hebei 056002, P.R. China
Published online on: July 22, 2014 https://doi.org/10.3892/ol.2014.2372
Pages: 1625-1627

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Abstract

Clear cell sarcoma of soft tissues is a very rare, malignant soft tissue tumor that usually arises in the extremities, with a predilection for the lower limbs. This report presents a 45‑year‑old male with a painless mass in the right lumbar region for one year. Magnetic resonance imaging showed a 3.6x3.2x1.5‑cm soft tissue mass of the right lumbar region. The tumoral cells had pleomorphic nuclei and large amounts of clear cytoplasm, and a proportion of the cells contained melanin. Immunohistochemical analysis was performed, which identified that the cells were positive for S‑100, MITF and HMB‑45 tumor markers. The patient underwent a postoperative chemotherapy protocol and had no local recurrences at one year post‑surgery.

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